The proximal C-terminus of α1C subunits is necessary for junctional membrane targeting of cardiac L-type calcium channels

Biochemical Journal

Volumn 448, Issue 2, 2012, Pages 221-231

  Nakada, Tsutomu ^a   Flucher, Bernhard E ^b   Kashihara, Toshihide ^a   Sheng, Xiaona ^a,c,d   Shibazaki, Toshihide ^a,e   Horiuchi Hirose, Miwa ^a   Gomi, Simmon ^a   Hirose, Masamichi ^f   Yamada, Mitsuhiko ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^c SHINSHU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d HEBEI MEDICAL UNIVERSITY   (China)

^e KISSEI PHARMACEUTICAL CO LTD   (Japan)

^f IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Cav1.2; Cardiac myocyte; Couplon; Excitation contraction coupling; Junctional membrane complex

Indexed keywords

ALANINE; CALCIUM CHANNEL L TYPE; GREEN FLUORESCENT PROTEIN;

ALPHA HELIX; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CHIMERA; CONTROLLED STUDY; DELETION MUTANT; GENE MUTATION; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; JUNCTIONAL MEMBRANE; MOUSE; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SUBUNIT; PROTEIN TARGETING;

ACTION POTENTIALS; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CELL LINE; CELL MEMBRANE; MICE; MODELS, MOLECULAR; MUTAGENESIS; MYOCYTES, CARDIAC; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; RABBITS; RECOMBINANT FUSION PROTEINS;

CHIMAERIFORMES;

EID: 84869033383     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20120773     Document Type: Article

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