Serum pepsinogens, gastrin-17 and Helicobacter pylori antibody in the residents of two cities in China with distinct mortality rates of gastric cancer

Tohoku Journal of Experimental Medicine

Volumn 228, Issue 4, 2012, Pages 289-294

  Zheng, Kui Cheng ^a,b   Aoki, Kazuo ^c   Li, Xiao Qing ^a   Lin, Shu Guang ^a   Bing Shan, Wu ^a   Zhong, Wen Ling ^a   Chen, Tie Hui ^a   Lin, Song ^d   You, Jian Wang ^e   Chang, Su ^a  

^a Fujian Provincial Center for Disease Control and Prevention   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c UNIVERSITY OF THE RYUKYUS   (Japan)

^d Fuan Center for Disease Control and Prevention   (China)

^e Changle Center for Disease Control and Prevention   (China)

Author keywords

Atrophic gastritis; Gastric cancer; Gastrin; Helicobacter pylori antibody; Pepsinogen

Indexed keywords

BACTERIUM ANTIBODY; GASTRIN 17; IMMUNOGLOBULIN G ANTIBODY; PEPSINOGEN; PEPSINOGEN I; PEPSINOGEN II;

ADULT; AGED; ANTIBODY BLOOD LEVEL; ANTIBODY DETECTION; ARTICLE; CANCER MORTALITY; CANCER RISK; CHINA; COMPARATIVE STUDY; DISEASE ASSOCIATION; FEMALE; GEOGRAPHIC DISTRIBUTION; HELICOBACTER PYLORI; HIGH RISK POPULATION; HUMAN; MALE; PREVALENCE; PROTEIN BLOOD LEVEL; SEROLOGY; STOMACH CANCER;

ADULT; AGED; ANTIBODIES, BACTERIAL; CHINA; CITIES; FEMALE; GASTRINS; GEOGRAPHY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; PEPSINOGEN A; PEPSINOGEN C; PEPSINOGENS; RESIDENCE CHARACTERISTICS; STOMACH NEOPLASMS;

EID: 84869025888     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.228.289     Document Type: Article

References (29)

1. Adamu, M.A., Weck, M.N., Rothenbacher, D. & Brenner, H. (2011) Incidence and risk factors for the development of chronic atrophic gastritis: five year follow-up of a populationbased cohort study. Int. J. Cancer, 128, 1652-1658.
2. Aromaa, A., Kosunen, T.U., Knekt, P., Maatela, J., Teppo, L., Heinonen, O.P., Härkönen, M. & Hakama, M.K. (1996) Circulating anti-Helicobacter pylori immunoglobulin A antibodies and low serum pepsinogen I level are associated with increased risk of gastric cancer. Am. J. Epidemiol., 144, 142-149.
3. Borch, K., Axelsson, C.K., Halgreen, H., Damkjaer Nielsen, M.D., Ledin, T. & Szesci, P.B. (1989) The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis. Scand. J. Gastroenterol., 24, 870-876.
4. Broutet, N., Plebani, M., Sakarovitch, C., Sipponen, P., Megraud, F.; the Eurohepygast Study Group. (2003) Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics. Br. J. Cancer., 88, 1239-1247.
5. Cao, Q., Ran, Z.H. & Xiao, S.D. (2007) Screening of atrophic gastritis and gastric cancer by serum pepsinogen, gastrin-17 and Helicobacter pylori immunoglobulin G antibodies. J. Dig. Dis., 8, 15-22.
6. Fujian Provincial Center for Disease Control and Prevention. (2009) Report on Chronic Disease Surveillance in Fujian in 2008. 14-15.
7. Fujian Provincial Center for Disease Control and Prevention. (2011) Report on Chronic Disease Surveillance in Fujian in 2010. 12-14.
8. Gatta, L., Di Mario, F., Vaira, D., Rugge, M., Franzè, A., Plebani, M., Cavestro, GM., Lucarini, P., Lera, M. & Scarpignato, C. (2011) Quantification of serum levels of pepsinogens and gastrin to assess eradication of Helicobacter pylori. Clin. Gastroenterol. Hepatol., 9, 440-442.
9. Germaná, B., Di Mario, F., Cavallaro, L.G., Moussa, A.M., Lecis, P., Liatoupolou, S., Comparato, G., Carloni, C., Bertiato, G., Battiestel, M., Papa, N., Aragona, G., Cavestro, G.M., Iori, V., Merli, R., Bertolini, S., Caruana, P. & Franzé, A. (2005) Clinical usefulness of serum pepsinogens I and II, gastrin-17 and anti-Helicobacter pylori antibodies in the management of dyspeptic patients in primary care. Dig. Liver Dis., 37, 501-508.
10. Howson, C.P., Hiyama, T. & Wynder, E.L. (1986) The decline in gastric cancer: epidemiology of an unplanned triumph. Epidemiol. Rev., 8, 1-27.
11. Kato, I., Tominaga, S., Ito, Y., Kobayashi, S., Yoshii, Y., Matsuura, A., Kameya, A., Kano, T. & Ikari, A. (1992) A prospective study of atrophic gastritis and stomach cancer risk. Jpn. J. Cancer Res., 83, 1137-1142.
12. Kikuchi, R., Abe, Y., lijima, K., Koike, T., Ara, N., Uno, K., Asanuma, K., Asano, N., Imatani, A. & Shimosegawa, T. (2011) Low serum levels of pepsinogen and gastrin 17 are predictive of extensive gastric atrophy with high-risk of early gastric cancer. Tohoku I Exp. Med., 223, 35-44.
13. Kitahara, F., Kobayashi, K., Sato, T., Kojima, Y., Araki, T. & Fujino, M.A. (1999) Accuracy of screening for gastric cancer using serum pepsinogen concentrations. Gut, 44, 693-697.
14. Maaroos, H.I., Vorobjova, T., Sipponen, P., Tammur, R., Uibo, R., Wadström, T., Keevallik, R. & Villako, K. (1999) An 18-year follow-up study of chronic gastritis and Helicobacter pylori association of CagA positivity with development of atrophy and activity of gastritis. Scand. J. Gastroenterol., 34, 864-869.
15. Malfertheiner, P., Sipponen, P., Naumann, M., Moayyedi, P., Mégraud, F., Xiao, S.D., Sugano, K. & Nyrén, O. (2005) Helicobacter pylori eradication has the potential to prevent gastric cancer: a state-of-the-art critique. Am. J. Gastroenterol., 100, 2100-2115.
16. McFarlane, G.A. & Munro, A. (1997) Helicobacter pylori and gastric cancer. Br I Surg., 84, 1190-1199.
17. Nomura, A., Yamakawa, H., Ishidate, T., Kamiyama, S., Masuda, H., Stemmermann, G.N., Heilburn, L.K. & Hankin, J.H. (1982) Intestinal metaplasia in Japan: association with diet. J. Natl. Cancer Inst., 68, 401-405.
18. Ohata, H., Kitauchi, S., Yoshimura, N., Mugitani, K., Iwane, M., Nakamura, H., Yoshikawa, A., Yanaoka, K., Arri, K., Tamai, H., Shimizu, Y., Takeshita, T., Mohara, O. & Ichinose, M. (2004) Progression of chronic atrophic gastritis associated with Helicobacter pylori infection increases risk of gastric cancer. Int. J. Cancer, 109, 138-143.
19. Oishi, Y., Kiyohara, Y., Kubo, M., Tanaka, K., Tanizaki, Y., Ninomiya, T., Doi, Y., Shikata, K., Yonemoto, K., Shirota, T., Matsumoto, T. & Iida, M. (2006) The serum pepsinogen test as a predictor of gastric cancer: the Hisayama study. Am. J. Epidemiol., 163, 629-637.
20. Rollan, A., Ferreccio, C., Gederlini, A., Serrano, C., Torres, J. & Harris, P. (2006) Non-invasive diagnosis of gastric mucosal atrophy in an asymptomatic population with high prevalence of gastric cancer. World I Gastroenterol., 12, 7172-7178.
21. Samloff, I.M. (1971) Cellular localization of group I pepsinogens in human gastric mucosa by immunofluorescence. Gastroenterology, 61, 185-188.
22. Samloff, I.M. & Liebman, W.M. (1973) Cellular localization of the group II pepsinogens in human stomach and duodenum by immunofluorescence. Gastroenterology, 65, 36-42.
23. Shiotani, A., Iishi, H., Uedo, N., Kumamoto, M., Nakae, Y., Ishiguro, S., Tatsuta, M. & Graham, D.Y. (2005) Histologic and serum risk markers for noncardia early gastric cancer. Int. I Cancer, 115, 463-469.
24. The Eurogast Study Group. (1993) An international association between Helicobacter pylori infection and gastric cancer. Lancet, 341, 1359-1362.
25. Uemura, N., Okamoto, S., Yamamoto, S., Matsumura, N., Yamaguchi, S., Yamakido, M., Taniyama, K., Sasaki, N. & Schlemper, R.J. (2001) Helicobacter pylori infection and the development of gastric cancer. N. Engl. J. Med., 345, 784-789.
26. Valle, J., Kekki, M., Sipponen, P., Ihamäki, T. & Siurala, M. (1996) Long-term course and consequences of Helicobacter pylori gastritis. Results of a 32-year follow-up study. Scand. J. Gastroenterol., 31, 546-550.
27. Varis, K., Kekki, M., Härkönen, M., Sipponen, P. & Samloff, I.M. (1991) Serum pepsinogen I and serum gastrin in the screening of atrophic pangastritis with high risk of gastric cancer. Scand. J Gastroenterol. Suppl., 186, 117-123.
28. Varis, K., Sipponen, P., Laxén, F., Samloff, I.M., Huttunen, J.K., Taylor, P.R., Heinonen, O.P., Albanes, D., Sande, N., Virtamo, J. & Härkönen, M. (2000) Implications of serum pepsinogen I in early endoscopic diagnosis of gastric cancer and dysplasia. Helsinki Gastritis Study Group. Scand. J. Gastroenterol., 35, 950-956.
29. Watabe, H., Mitsushima, T., Yamaji, Y., Okamoto, M., Wada, R., Kokubo, T., Doi, H., Yoshida, H., Kawabe, T. & Omata, M. (2005) Predicting the development of gastric cancer from combining Helicobacter pylori antibodies and serum pepsiogen status: a prospective endoscopic cohort study. Gut, 54, 764-768.