메뉴 건너뛰기




Volumn 64, Issue 10, 2012, Pages 3111-3118

Rituximab mediates loss of CD19 on B cells in the absence of cell death

Author keywords

[No Author keywords available]

Indexed keywords

CD19 ANTIGEN; CD20 ANTIGEN; CELL SURFACE PROTEIN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C5; MESSENGER RNA; RITUXIMAB;

EID: 84869017339     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.34560     Document Type: Article
Times cited : (47)

References (23)
  • 1
    • 34548221347 scopus 로고    scopus 로고
    • Mechanisms of killing by anti-CD20 monoclonal antibodies
    • DOI 10.1016/j.molimm.2007.06.151, PII S0161589007002623, XIth European meeting on Complement in Human Disease
    • Glennie MJ, French RR, Cragg MS, Taylor RP. Mechanisms of killing by anti-CD20 monoclonal antibodies [review]. Mol Immunol 2007; 44: 3823-37. (Pubitemid 47332625)
    • (2007) Molecular Immunology , vol.44 , Issue.16 , pp. 3823-3837
    • Glennie, M.J.1    French, R.R.2    Cragg, M.S.3    Taylor, R.P.4
  • 3
    • 33746961890 scopus 로고    scopus 로고
    • Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy
    • for the REFLEX Trial Group
    • Cohen SB, Emery P, Greenwald MW, Dougados M, Furie RA, Genovese MC, et al, for the REFLEX Trial Group. Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy. Arthritis Rheum 2006; 54: 2793-806.
    • (2006) Arthritis Rheum , vol.54 , pp. 2793-2806
    • Cohen, S.B.1    Emery, P.2    Greenwald, M.W.3    Dougados, M.4    Furie, R.A.5    Genovese, M.C.6
  • 4
    • 33646483031 scopus 로고    scopus 로고
    • The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: Results of a phase IIb randomized, double-blind, placebo-controlled, doseranging trial
    • for the DANCER Study Group
    • Emery P, Fleischmann R, Filipowicz-Sosnowska A, Schechtman J, Szczepanski L, Kavanaugh A, et al, for the DANCER Study Group. The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase IIb randomized, double-blind, placebo-controlled, doseranging trial. Arthritis Rheum 2006; 54: 1390-400.
    • (2006) Arthritis Rheum , vol.54 , pp. 1390-1400
    • Emery, P.1    Fleischmann, R.2    Filipowicz-Sosnowska, A.3    Schechtman, J.4    Szczepanski, L.5    Kavanaugh, A.6
  • 6
    • 0023751336 scopus 로고
    • Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells
    • Gough NM. Rapid and quantitative preparation of cytoplasmic RNA from small numbers of cells. Anal Biochem 1988;173: 93-95.
    • (1988) Anal Biochem , vol.173 , pp. 93-95
    • Gough, N.M.1
  • 7
    • 32044464340 scopus 로고    scopus 로고
    • The shaving reaction: Rituximab/CD20 complexes are removed from mantle cell lymphoma and chronic lymphocytic leukemia cells by THP-1 monocytes
    • Beum PV, Kennedy AD, Williams ME, Lindofer MA, Taylor RP. The shaving reaction: rituximab/CD20 complexes are removed from mantle cell lymphoma and chronic lymphocytic leukemia cells by THP-1 monocytes. J Immunol 2006; 176: 2600-9. (Pubitemid 43201712)
    • (2006) Journal of Immunology , vol.176 , Issue.4 , pp. 2600-2609
    • Beum, P.V.1    Kennedy, A.D.2    Williams, M.E.3    Lindorfer, M.A.4    Taylor, R.P.5
  • 8
    • 79955020374 scopus 로고    scopus 로고
    • Monocytes mediate shaving of B-cell-bound anti-CD20 antibodies
    • Pedersen AE, Jungersen MB, Pedersen CD. Monocytes mediate shaving of B-cell-bound anti-CD20 antibodies. Immunology 2011; 133:239-45.
    • (2011) Immunology , vol.133 , pp. 239-245
    • Pedersen, A.E.1    Jungersen, M.B.2    Pedersen, C.D.3
  • 10
    • 51049120495 scopus 로고    scopus 로고
    • Differential cellular internalization of anti-CD19 and -CD22 immunotoxins results in different cytotoxic activity
    • Du X, Beers R, Fitzgerald DJ, Pastan I. Differential cellular internalization of anti-CD19 and -CD22 immunotoxins results in different cytotoxic activity. Cancer Res 2008; 68: 6300-5.
    • (2008) Cancer Res , vol.68 , pp. 6300-6305
    • Du, X.1    Beers, R.2    Fitzgerald, D.J.3    Pastan, I.4
  • 11
    • 36849080318 scopus 로고    scopus 로고
    • High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate
    • DOI 10.1111/j.1365-2141.2007.06883.x
    • Ingle GS, Chan P, Elliott JM, Chang WS, Koeppen H, Stephan JP, et al. High CD21 expression inhibits internalization of anti-CD19 antibodies and cytotoxicity of an anti-CD19-drug conjugate. Br J Haematol 2008; 140: 46-58. (Pubitemid 350233252)
    • (2008) British Journal of Haematology , vol.140 , Issue.1 , pp. 46-58
    • Ingle, G.S.1    Chan, P.2    Elliott, J.M.3    Chang, W.S.4    Koeppen, H.5    Stephan, J.-P.6    Scales, S.J.7
  • 12
    • 80053080677 scopus 로고    scopus 로고
    • Loss of CD20 and bound CD20 antibody from opsonized B cells occurs more rapidly because of trogocytosis mediated by Fc receptor-expressing effector cells than direct internalization by the B cells
    • Beum PV, Peek EM, Lindorfer MA, Beurskens FJ, Engelberts PJ, Parren PW, et al. Loss of CD20 and bound CD20 antibody from opsonized B cells occurs more rapidly because of trogocytosis mediated by Fc receptor-expressing effector cells than direct internalization by the B cells. J Immunol 2011;187: 3438-47.
    • (2011) J Immunol , vol.187 , pp. 3438-3447
    • Beum, P.V.1    Peek, E.M.2    Lindorfer, M.A.3    Beurskens, F.J.4    Engelberts, P.J.5    Parren, P.W.6
  • 13
    • 68949129063 scopus 로고    scopus 로고
    • Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): Considerably higher levels of CDC are induced by OFA than RTX
    • Pawluczkowycz AW, Beurskens FJ, Beum PV, Lindorfer MA, van de Winkel JG, Parren PW, et al. Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than RTX. J Immunol 2009; 183: 749-58.
    • (2009) J Immunol , vol.183 , pp. 749-758
    • Pawluczkowycz, A.W.1    Beurskens, F.J.2    Beum, P.V.3    Lindorfer, M.A.4    Van De Winkel, J.G.5    Parren, P.W.6
  • 14
    • 46949089844 scopus 로고    scopus 로고
    • Mapping of binding epitopes of a human decay-accelerating factor monoclonal antibody capable of enhancing rituximab-mediated complement-dependent cytotoxicity
    • Guo B, Ma Z, Li H, Xu G, Zheng P, Zhu B, et al. Mapping of binding epitopes of a human decay-accelerating factor monoclonal antibody capable of enhancing rituximab-mediated complement-dependent cytotoxicity. Clin Immunol 2008;128: 155-63.
    • (2008) Clin Immunol , vol.128 , pp. 155-163
    • Guo, B.1    Ma, Z.2    Li, H.3    Xu, G.4    Zheng, P.5    Zhu, B.6
  • 15
    • 33746047673 scopus 로고    scopus 로고
    • Complement-induced cell death by rituximab depends on CD20 expression level and acts complementary to antibody-dependent cellular cytotoxicity
    • DOI 10.1158/1078-0432.CCR-06-0066
    • Van Meerten T, van Rijn RS, Hol S, Hagenbeek A, Ebeling SB. Complement-induced cell death by rituximab depends on CD20 expression level and acts complementary to antibody-dependent cellular cytotoxicity. Clin Cancer Res 2006; 12: 4027-35. (Pubitemid 44078090)
    • (2006) Clinical Cancer Research , vol.12 , Issue.13 , pp. 4027-4035
    • Van Meerten, T.1    Van Rijn, R.S.2    Hol, S.3    Hagenbeek, A.4    Ebeling, S.B.5
  • 16
    • 48549100414 scopus 로고    scopus 로고
    • Immunotherapeutic mechanisms of anti-CD20 monoclonal antibodies [review]
    • Taylor RP, Lindorfer MA. Immunotherapeutic mechanisms of anti-CD20 monoclonal antibodies [review]. Curr Opin Immunol 2008; 20: 444-9.
    • (2008) Curr Opin Immunol , vol.20 , pp. 444-449
    • Taylor, R.P.1    Lindorfer, M.A.2
  • 17
    • 53149151480 scopus 로고    scopus 로고
    • Within peripheral blood mononuclear cells, antibody-dependent cellular cytotoxicity of rituximab-opsonized Daudi cells is promoted by NK cells and inhibited by monocytes due to shaving
    • Beum PV, Lindorfer MA, Taylor RP. Within peripheral blood mononuclear cells, antibody-dependent cellular cytotoxicity of rituximab-opsonized Daudi cells is promoted by NK cells and inhibited by monocytes due to shaving. J Immunol 2008;181: 2916-24.
    • (2008) J Immunol , vol.181 , pp. 2916-2924
    • Beum, P.V.1    Lindorfer, M.A.2    Taylor, R.P.3
  • 18
    • 35748962939 scopus 로고    scopus 로고
    • Rituximab-CD20 complexes are shaved from Z138 mantle cell lymphoma cells in intravenous and subcutaneous SCID mouse models
    • Li Y, Williams ME, Cousar JB, Pawluczkowycz AW, Lindorfer MA, Taylor RP. Rituximab-CD20 complexes are shaved from Z138 mantle cell lymphoma cells in intravenous and subcutaneous SCID mouse models. J Immunol 2007; 179: 4263-71.
    • (2007) J Immunol , vol.179 , pp. 4263-4271
    • Li, Y.1    Williams, M.E.2    Cousar, J.B.3    Pawluczkowycz, A.W.4    Lindorfer, M.A.5    Taylor, R.P.6
  • 20
    • 39049095216 scopus 로고    scopus 로고
    • Rituximab pharmacokinetics in patients with rheumatoid arthritis: B-cell levels do not correlate with clinical response
    • Breedveld F, Agarwal S, Yin M, Ren S, Li NF, Shaw TM, et al. Rituximab pharmacokinetics in patients with rheumatoid arthritis: B-cell levels do not correlate with clinical response. J Clin Pharmacol 2007; 47: 1119-28.
    • (2007) J Clin Pharmacol , vol.47 , pp. 1119-1128
    • Breedveld, F.1    Agarwal, S.2    Yin, M.3    Ren, S.4    Li, N.F.5    Shaw, T.M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.