Phase-specific brain change of spatial working memory processing in genetic and ultra-high risk groups of schizophrenia

Schizophrenia Bulletin

Volumn 38, Issue 6, 2012, Pages 1189-1199

  Choi, Jung Seok ^a,b   Park, Ji Young ^c   Jung, Myung Hun ^a   Jang, Joon Hwan ^a   Kang, Do Hyung ^a   Jung, Wi Hoon ^c   Han, Ji Yeon ^c   Choi, Chi Hoon ^d   Hong, Kyung Sue ^e   Kwon, Jun Soo ^a,c  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University Boramae Hospital   (South Korea)

^c Seoul National University   (South Korea)

^d National Medical Center   (South Korea)

^e Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

first degree relative; functional MRI; schizophrenia; spatial working memory; ultra high risk

Indexed keywords

ADULT; ARTICLE; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENETIC RISK; HIGH RISK POPULATION; HUMAN; MALE; NEUROIMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA; SPATIAL MEMORY; SPATIAL WORKING MEMORY; SUPERIOR TEMPORAL GYRUS; TASK PERFORMANCE; WORKING MEMORY;

ADOLESCENT; ADULT; BRAIN; BRAIN MAPPING; CASE-CONTROL STUDIES; FAMILY; FEMALE; FRONTAL LOBE; FUNCTIONAL NEUROIMAGING; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; PARIETAL LOBE; PRODROMAL SYMPTOMS; REACTION TIME; RISK; SCHIZOPHRENIA; TEMPORAL LOBE; THALAMUS;

EID: 84869007921     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbr038     Document Type: Article

References (48)

1. Baddeley A. Working memory. Science. 1992;255:556-559.
2. Goldman-Rakic PS. Working memory dysfunction in schizophrenia. J Neuropsychiatry Clin Neurosci. 1994;6:348-357.
3. Cannon TD, Huttunen MO, Lonnqvist J, et al. The inheritance of neuropsychological dysfunction in twins discordant for schizophrenia. Am J Hum Genet. 2000;67:369-382.
4. Park S, Holzman PS. Schizophrenics show spatial working memory deficits. Arch Gen Psychiatry. 1992;49:975-982.
5. Pirkola T, Tuulio-Henriksson A, Glahn D, et al. Spatial working memory function in twins with schizophrenia and bipolar disorder. Biol Psychiatry. 2005;58:930-936.
6. Smith CW, Park S, Cornblatt B. Spatial working memory deficits in adolescents at clinical high risk for schizophrenia. Schizophr Res. 2006;81:211-215.
7. Kim JJ, Kwon JS, Park HJ, et al. Functional disconnection between the prefrontal and parietal cortices during working memory processing in schizophrenia: a [15O]H2O PET study. Am J Psychiatry. 2003;160:919-923.
8. Broome MR, Matthiasson P, Fusar-Poli P, et al. Neural correlates of executive function and working memory in the 'atrisk mental state'. Br J Psychiatry. 2009;194:25-33.
9. Callicott JH, Egan MF, Mattay VS, et al. Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia. Am J Psychiatry. 2003;160:709-719.
10. Seidman LJ, Thermenos HW, Poldrack RA, et al. Altered brain activation in dorsolateral prefrontal cortex in adolescents and young adults at genetic risk for schizophrenia: an fMRI study of working memory. Schizophr Res. 2006;85:58-72.
11. Thermenos HW, Seidman LJ, Breiter H, et al. Functional magnetic resonance imaging during auditory verbal working memory in nonpsychotic relatives of persons with schizophrenia: a pilot study. Biol Psychiatry. 2004;55:490-500.
12. Cairo TA, Liddle PF, Woodward TS, Ngan ET. The influence of working memory load on phase specific patterns of cortical acticity. Brain Res Cogn Brain Res. 2004;21:377-387.
13. Manoach DS. Prefrontal cortex dysfunction during working memory performance in schizophrenia: reconciling discrepant findings. Schizophr Res. 2003;60:285-298.
14. Woodward TS, Cairo TA, Ruff CC, Takane Y, Hunter MA, Ngan ET. Functional connectivity reveals load dependent neural systems underlying encoding and maintenance in verbal working memory. Neuroscience. 2006;139:317-325.
15. Tek C, Gold J, Blaxton T, Wilk C, McMahon RP, Buchanan RW. Visual perceptual and working memory impairments in schizophrenia. Arch Gen Psychiatry. 2002;59:146-153.
16. Schlo sser RG, Koch K, Wagner G, et al. Inefficient executive cognitive control in schizophrenia is preceded by altered functional activation during information encoding: an fMRI study. Neuropsychologia. 2008;46:336-347.
17. Cannon TD, Glahn DC, Kim J, et al. Dorsolateral prefrontal cortex activity during maintenance and manipulation of information in working memory in patients with schizophrenia. Arch Gen Psychiatry. 2005;62:1071-1080.
18. First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview For DSM-IV Axis I Disorder. New York: New York State Psychiatric Institute; 1996.
19. Choi JS, Kang DH, Park JY, et al. Cavum septum pellucidum in subjects at ultra-high risk for psychosis: compared with first-degree relatives of patients with schizophrenia and healthy volunteers. Prog Neuropsychopharmacol Biol Psychiatry. 2008;32:1326-1330.
20. Jung MH, Jang JH, Kang DH, et al. The reliability and validity of the Korean version of the structured interview for prodromal syndrome. Psychiatry Investig. 2010;7:257-263.
21. Yung AR, Yuen HP, McGorry PD, et al. Mapping the onset of psychosis: the comprehensive assessment of at-risk mental states. Aust N Z J Psychiatry. 2005;39:964-971.
22. Nurnberger JI, Jr, Blehar MC, Kaufmann CA, et al. Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. Arch Gen Psychiatry. 1994;51:849-859.
23. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13:261-276.
24. Pessoa L, Gutierrez E, Bandettini P, Ungerleider L. Neural correlates of visual working memory: fMRI amplitude predicts task performance. Neuron. 2002;35:975-987.
25. Postle BR, Druzgal TJ, D'Esposito M. Seeking the neural substrates of visual working memory storage. Cortex. 2003;39:927-946.
26. Zarahn E, Aguirre G, D'Esposito M. A trial-based experimental design for fMRI. Neuroimage. 1997;6:122-138.
27. Ollinger JM, Corbetta M, Shulman GL. Separating processes within a trial in event-related functional MRI. Neuroimage. 2001;13:218-229.
28. Haier RJ, Siegel BV, Jr, MacLachlan A, Soderling E, Lottenberg S, Buchsbaum MS. Regional glucose metabolic changes after learning a complex visuospatial/motor task: a positron emission tomographic study. Brain Res. 1992;570:134-143.
29. Ragland JD, Glahn DC, Gur RC, et al. PET regional cerebral blood flow change during working and declarative memory: relationship with task performance. Neuropsychology. 1997; 11:222-231.
30. Jansma JM, Ramsey NF, Slagter HA, Kahn RS. Functional anatomical correlates of controlled and automatic processing. J Cogn Neurosci. 2001;13:730-743.
31. Lee J, Folley BS, Gore J, Park S. Origins of spatial working memory deficits in schizophrenia: an event-related fMRI and near-infrared spectroscopy study. PLoS One. 2008; 3:e1760.
32. McAvoy MP, Ollinger JM, Buckner RL. Cluster size thresholds for assessment of significant activation in fMRI. Neuroimage. 2001;13:S198.
33. Park S, Holzman PS, Goldman-Rakic PS. Spatial working memory deficits in the relatives of schizophrenic patients. Arch Gen Psychiatry. 1995;52:821-828.
34. Myles-Worsley M, Park S. Spatial working memory deficits in schizophrenia patients and their first degree relatives from Palau, Micronesia. Am J Med Genet. 2002;114:609-615.
35. Meda SA, Stevens MC, Folley BS, Calhoun VD, Pearlson GD. Evidence for anomalous network connectivity during working memory encoding in schizophrenia: an ICA based analysis. PLoS One. 2009;4:e7911.
36. Johnson MR, Morris NA, Astur RS, et al. A functional magnetic resonance imaging study of working memory abnormalities in schizophrenia. Biol Psychiatry. 2006; 60:11-21.
37. Manoach DS, Gollub RL, Benson ES, et al. Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance. Biol Psychiatry. 2000;48:99-109.
38. Cairo TA, Woodward TS, Ngan ET. Decreased encoding efficiency in schizophrenia. Biol Psychiatry. 2006;59:740-746.
39. Popken GJ, BunneyWE, Jr, Potkin SG, Jones EG. Subnucleusspecific loss of neurons in medial thalamus of schizophrenics. Proc Natl Acad Sci U S A. 2000;97:9276-9280.
40. Yoo SY, Yeon S, Choi CH, et al. Proton magnetic resonance spectroscopy in subjects with high genetic risk of schizophrenia: investigation of anterior cingulate, dorsolateral prefrontal cortex and thalamus. Schizophr Res. 2009;111:86-93.
41. Tanibuchi I, Goldman-Rakic PS. Dissociation of spatial-, object-, and sound-coding neurons in the mediodorsal nucleus of the primate thalamus. J Neurophysiol. 2003;89:1067-1077.
42. Watanabe Y, Funahashi S. Neuronal activity throughout the primate mediodorsal nucleus of the thalamus during oculomotor delayed-responses. II. Activity encoding visual versus motor signal. J Neurophysiol. 2004;92:1756-1769.
43. Yassa MA, Verduzco G, Cristinzio C, Bassett SS. Altered fMRI activation during mental rotation in those at genetic risk for Alzheimer disease. Neurology. 2008;70:1898-1904.
44. Fletcher PC, Frith CD, Grasby PM, Friston KJ, Dolan RJ. Local and distributed effects of apomorphine on frontotemporal function in acute unmedicated schizophrenia. J Neurosci. 1996;16:7055-7062.
45. Gur RE, Turetsky BI, Loughead J, et al. Visual attention circuitry in schizophrenia investigated with oddball eventrelatedfunctionalmagnetic resonanceimaging.AmJPsychiatry. 2007;164:442-449.
46. Crottaz-Herbette S, Anagnoson RT, Menon V. Modality effects in verbal working memory: differential prefrontal and parietal responses to auditory and visual stimuli. Neuroimage. 2004;21:340-351.
47. Walter H, Vasic N, Ho se A, Spitzer M, Wolf RC. Working memory dysfunction in schizophrenia compared to healthy controls and patients with depression: evidence from eventrelated fMRI. Neuroimage. 2007;35:1551-1561.
48. Crossley NA, Mechelli A, Fusar-Poli P, et al. Superior temporal lobe dysfunction and frontotemporal dysconnectivity in subjects at risk of psychosis and in first-episode psychosis. Hum Brain Mapp. 2009;30:4129-4137.