Relationship of circulating tumor cells to the effectiveness of cytotoxic chemotherapy in patients with metastatic non-small-cell lung cancer

Oncology Research

Volumn 20, Issue 2-3, 2012, Pages 131-137

  Hirose, Takashi ^a   Murata, Yasunori ^a   Oki, Yasunari ^a   Sugiyama, Tomohide ^a   Kusumoto, Sojiro ^a   Ishida, Hiroo ^a   Shirai, Takao ^a   Nakashima, Masano ^a   Yamaoka, Toshimitsu ^a   Okuda, Kentaro ^a   Ohnishi, Tsukasa ^a   Ohmori, Tohru ^a  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Chemotherapy; Circulating tumor cells (CTCs); Non small cell lung cancer (NSCLC); Predictive factor

Indexed keywords

CARBOPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; EPITHELIAL CELL ADHESION MOLECULE; GEMCITABINE;

ADULT; AGED; ARTICLE; CIRCULATING TUMOR CELL; CLINICAL ARTICLE; COMBINATION CHEMOTHERAPY; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; LIFE EXPECTANCY; LUNG NON SMALL CELL CANCER; MALE; METASTASIS; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; TREATMENT RESPONSE;

EID: 84869003422     PISSN: 09650407     EISSN: 15553906     Source Type: Journal    
DOI: 10.3727/096504012X13473664562583     Document Type: Article

References (19)

1. Schiller, J. H.; Harrington, D.; Belani, C. P.; Langer, C.; Sandler, A.; Krook, J.; Zhu, J.; Johnson, D. H., for the Eastern Cooperative Oncology Group. Comparison of four chemotherapy regimens for advanced non-small-cell cancer. N. Engl. J. Med. 346:92-98; 2002.
2. Ohe, Y.; Ohashi, Y.; Kubota, K.; Tamura, T.; Nakagawa, K.; Negoro, S.; Nishiwaki, Y.; Saijo, N.; Ariyoshi, Y.; Fukuoka, M., for the FACS Cooperative Group. Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and cisplatin plus vinorelbine for advanced non-small cell lung cancer: Four-arm cooperative study in Japan. Ann. Oncol. 18:317-323; 2007.
3. Sandler, A.; Gray, R.; Perry, M.; Brahmer, J.; Schiller, J. H.; Dowlati, A.; Lilenbaum, R.; Johnson, D. H. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N. Engl. J. Med. 355:2542-2550; 2006.
4. Maemondo, M.; Inoue, A.; Kobayashi, K.; Sugawara, S.; Oizumi, S.; Isobe, H.; Gemma, A.; Harada, M.; Yoshizawa, H.; Kinoshita, I.; Fujita, Y.; Okinaga, S.; Hirano, H.; Yoshimori, K.; Harada, T.; Ogura, T.; Ando, M.; Miyazawa, H.; Tanaka, T.; Saijo, Y.; Hagiwara, K.; Morita, S.; Nukiwa, T., for the North-East Japan Study Group. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N. Engl. J. Med. 362:2380-2388; 2010.
5. Mitsudomi, T.; Morita, S.; Yatabe, Y.; Negoro, S.; Okamoto, I.; Tsurutani, J.; Seto, T.; Satouchi, M.; Tada, H.; Hirashima, T.; Asami, K.; Katakami, N.; Takada, M.; Yoshioka, H.; Shibata, K.; Kudoh, S.; Shimizu, E.; Saito, H.; Nakagawa, K.; Fukuoka, M., for the West Japan Oncology Group. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial. Lancet Oncol. 11:121-128; 2010.
6. Kwak, E. L.; Bang, Y. J.; Camidge, R.; Shaw, A. T.; Solomon, B.; Maki, R. G.; Ou, S. H. I.; Dezube, B. J.; Janne, P. A.; Costa, D. B.; Varella-Garcia, M.; Kim, W. H.; Lynch, T. J.; Fidias, P.; Stubbs, H.; Engelman, J. A.; Sequist, L. V.; Tan, W.; Gandhi, L.; Mino-Kenudson, M.; Wei, G. C.; Shreeve, S. M.; Ratain, M. J.; Settleman, J.; Christensen, J. G.; Haber, D. A.; Wilner, K.; Salgia, R.; Shapiro, G. I.; Clark, J. W.; Iafrate, A. J. N. Anaplastic lymphoma kinase inhibiton in non-small-cell lung cancer. Engl. J. Med. 363:1693-1703; 2010.
7. Allard, W. J.; Matera, J.; Miller, M. C.; Repollet, M.; Connelly, M. C.; Rao, C.; Tibbe, A. G. J.; Uhr, J. W.; Terstappen, L. W. M. M. Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant disease. Clin. Cancer Res. 10:6897-6904; 2004.
8. Fehm, T.; Sagalowsky, A.; Clifford, E.; Beitsch, P.; Saboorian, H.; Euhus, D.; Meng, S.; Morrison, L.; Tucker, T.; Lane, N.; Ghadimi, B. M.; Heselmeyer-Haddad, K.; Ried, T.; Rao, C.; Uhr, J. Cytogenetic evidenced that circulating epithelial cells in patients with carcinoma are malignant. Clin. Cancer Res. 8:2073-2084; 2002.
9. Cristofanilli, M.; Budd, T.; Ellis, M. J.; Stopeck, A.; Matera, J.; Miller, C.; Reuben, J. M.; Doyle, G. V.; Allard, W. J.; Terstappen, L. W. M. M.; Hayes, D. F. Circulating tumor cells, disease progression, and survival in metastatic breast cancer. N. Engl. J. Med. 351:781-791; 2004.
10. Bono, J. S.; Scher, H. I.; Montgomery, B.; Parker, C.; Miller, M. C.; Tissing, H.; Doyle, G. V.; Terstappen, L. W. W. M.; Pienta, K. J.; Raghavan, D. Circulating tumor cells predict survival benefit from treatment in metastatic castration-resistant prostate cancer. Clin. Cancer Res. 14:6302-6309; 2008.
11. Cohen, S. J.; Punt, C. J. A.; Iannotti, N.; Saidman, B. H.; Sabbath, K. D.; Gabrail, N. Y.; Picus, J.; Morse, M.; Mitchell, E.; Miller, M. C.; Doyle, G. V.; Tissing, H.; Terstappen, L. W. W. M.; Meropol, N. J. Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. J. Clin. Oncol. 26:3213-3221; 2008.
12. Tanaka, F.; Yoneda, K.; Kondo, N.; Hashimoto, M.; Takuwa, T.; Matsumoto, S.; Okumura, Y.; Rahman, S.; Tsubota, N.; Tsujimura, T.; Kuribayashi, K.; Fukuoka, K.; Nakano, T.; Hasegawa, S. Circulating tumor cell as a diagnostic marker in primary lung cancer. Clin. Cancer Res. 15:6980-6986; 2009.
13. Krebs, M. G.; Sloane, R.; Priest, L.; Lancashire, L.; Hou, J. M.; Greystoke, A.; Ward, T. H.; Ferraldeschi, R.; Hughes, A.; Clack, G.; Ranson, M.; Dive, C.; Blackhall, F. H. Evaluation and prognostic significance of circulating tumor cells in patients with non-small-cell lung cancer. J. Clin. Oncol. 29:1556-1563; 2011.
14. Bidard, F. C.; Mathiot, C.; Delaloge, S.; Brain, E.; Giachetti, S.; de Cremoux, P.; Marty, M.; Pierga, J. Y. Single circulating tumor cell detection and overall survival in nonmetastatic breast cancer. Ann. Oncol. 21:729-733; 2010.
15. Budd, G. T.; Cristofanilli, M.; Ellis, M. J.; Stopeck, A.; Borden, E.; Miller, M. C.; Matera, J.; Repollet, M.; Doyle, G. V.; Terstappen, L. W. M. M.; Hayes, D. Circulating tumor cell versus imaging-predicting overall survival in metastatic breast cancer. Clin. Cancer Res. 12:6403-6409; 2006.
16. Gallagher, D. J.; Milowsky, M. I.; Ishill, N.; Trout, A.; Boyle, M. G.; Riches, J.; Fleisher, M.; Bajorin, D. F. Detection of circulating tumor cells in patients with urothelical cancer. Ann. Oncol. 20:305-308; 2009.
17. Nagrath, S.; Sequist, L. V.; Maheswaran, S.; Bell, D. W.; Irimia, D.; Ulkus, L.; Smith, M. R.; Kwak, E. L.; Digumarthy, S.; Muzikansky, A.; Ryan, P.; Balis, U. J.; Tompkins, R. G.; Haber, D. A.; Toner, M. Isolation of rare circulating tumor cells in cancer patients by microchip technology. Nature 450:1235-1239; 2007.
18. Wu, C.; Hao, H.; Li, L.; Zhou, X.; Guo, Z.; Zhang, L.; Zhang, X.; Zhong, W.; Guo, H.; Bremner, R. M.; Lin, P. Preliminary investigation of the clinical significance of detecting circulating tumor cells enriched from lung cancer patients. J. Thoracic. Oncol. 4:30-36; 2009.
19. Maheswaran, S.; Sequist, L. V.; Nagrath, S.; Ulkus, L.; Brannigan, B.; Collura, C. V.; Inserra, E.; Diederichs, S.; Iafrate, A. J.; Bell, D. W.; Digumarthy, S.; Muzikansky, A.; Irimia, D.; Settleman, J.; Tompkins, R. G.; Lynch, T. J.; Toner, M.; Haber, D. A. Detection of mutations in EGFR in circulating tumor cells. N. Engl. J. Med. 359:366-377; 2008.