-
1
-
-
77952773418
-
VHL and HIF signalling in renal cell carcinogenesis
-
Baldewijns MM, van Vlodrop IJ, Vermeulen PB, Soetekouw PM, van Engeland M, de Bruïne AP: VHL and HIF signalling in renal cell carcinogenesis. J Pathol 2010; 221:125-138.
-
(2010)
J Pathol
, vol.221
, pp. 125-138
-
-
Baldewijns, M.M.1
Van Vlodrop, I.J.2
Vermeulen, P.B.3
Soetekouw, P.M.4
Van Engeland, M.5
De Bruïne, A.P.6
-
2
-
-
79959692399
-
Vascular Endothelial Growth Factor-targeted Therapy for the Treatment of Renal Cell Carcinoma
-
Escudier B, Albiges L: Vascular endothelial growth factor-targeted therapy for the treatment of renal cell carcinoma. Drugs 2011; 71: 1179-1191.
-
(2011)
Drugs
, vol.71
, pp. 1179-1191
-
-
Escudier, B.1
Albiges, L.2
-
3
-
-
70349385645
-
Resistance to targeted therapy in renal-cell carcinoma
-
Rini BI, Atkins MB: Resistance to targeted therapy in renal-cell carcinoma. Lancet Oncol 2009; 10: 992-1000.
-
(2009)
Lancet Oncol
, vol.10
, pp. 992-1000
-
-
Rini, B.I.1
Atkins, M.B.2
-
4
-
-
22244470409
-
Stromal cell derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: Von Hip-pel-Lindau loss-of-function induces expression of a ligand and its receptor
-
Zagzag D, Krishnamachary B, Yee H, et al: Stromal cell derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hip-pel-Lindau loss-of-function induces expression of a ligand and its receptor. Cancer Res 2005; 65:6178-6188.
-
(2005)
Cancer Res
, vol.65
, pp. 6178-6188
-
-
Zagzag, D.1
Krishnamachary, B.2
Yee, H.3
-
5
-
-
79958052123
-
MDSC As A Mechanism of Tumor Escape from Sunitinib Mediated Anti-angio-genic Therapy
-
Finke J, Ko J, Rini B, Rayman P, Ireland J, Cohen P: MDSC as a mechanism of tumor escape from sunitinib mediated anti-angio-genic therapy. Int Immunopharmacol 2011; 11: 856-861.
-
(2011)
Int Immunopharmacol
, vol.11
, pp. 856-861
-
-
Finke, J.1
Ko, J.2
Rini, B.3
Rayman, P.4
Ireland, J.5
Cohen, P.6
-
6
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash J, Maisonpierre PC, Compton D, et al: Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 1999; 284: 1994-1998.
-
(1999)
Science
, vol.284
, pp. 1994-1998
-
-
Holash, J.1
Maisonpierre, P.C.2
Compton, D.3
-
7
-
-
33847048710
-
Alternative vascularization mechanisms in cancer: Pathology and therapeutic implications
-
Döme B, Hendrix MJ, Paku S, Tóvári J, Tímár J: Alternative vascularization mechanisms in cancer: pathology and therapeutic implications. Am J Pathol 2007; 170: 1-15.
-
(2007)
Am J Pathol
, vol.170
, pp. 1-15
-
-
Döme, B.1
Hendrix, M.J.2
Paku, S.3
Tóvári, J.4
Tímár, J.5
-
8
-
-
77953467629
-
Reversible Epithelial to Mesenchymal Transition and Acquired Resistance to Suni-tinib in Patients with Renal Cell Carcinoma: Evidence from A Xenograft Study
-
Hammers HJ, Verheul HM, Salumbides B, et al: Reversible epithelial to mesenchymal transition and acquired resistance to suni-tinib in patients with renal cell carcinoma: evidence from a xenograft study. Mol Cancer Ther 2010; 9: 1525-1535.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 1525-1535
-
-
Hammers, H.J.1
Verheul, H.M.2
Salumbides, B.3
-
9
-
-
76249133170
-
Interleu-kin-8 Mediates Resistance to Antiangiogenic Agent Sunitinib in Renal Cell Carcinoma
-
Huang D, Ding Y, Zhou M, et al: Interleu-kin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. Cancer Res 2010; 70:1063-1071.
-
(2010)
Cancer Res
, vol.70
, pp. 1063-1071
-
-
Huang, D.1
Ding, Y.2
Zhou, M.3
-
10
-
-
80053493427
-
Beyond v EGF: Inhibition of the Fi-broblast Growth Factor Pathway and Antian-giogenesis
-
Lieu C, Heymach J, Overman M, Tran H, Kopet z S: Beyond V EGF: inhibition of the fi-broblast growth factor pathway and antian-giogenesis. Clin Cancer Res 2011; 17:6130-6139.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6130-6139
-
-
Lieu, C.1
Heymach, J.2
Overman, M.3
Tran Kopet H, Z.S.4
-
11
-
-
79952538238
-
Fi-broblast Growth Factor 2 Regulates Endothe-lial Cell Sensitivity to Sunitinib
-
Welti JC, Gourlaouen M, Powles T, et al: Fi-broblast growth factor 2 regulates endothe-lial cell sensitivity to sunitinib. Oncogene 2011; 30:1183-1193.
-
(2011)
Oncogene
, vol.30
, pp. 1183-1193
-
-
Welti, J.C.1
Gourlaouen, M.2
Powles, T.3
Et Al.4
-
12
-
-
0142250392
-
Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: A review of the rationale and clinical evidence
-
Trikha M, Corringham R, Klein B, Rossi JF: Targeted anti-interleukin-6 monoclonal antibody therapy for cancer: a review of the rationale and clinical evidence. Clin Cancer Res 2003; 9: 4653-4665.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4653-4665
-
-
Trikha, M.1
Corringham, R.2
Klein, B.3
Rossi, J.F.4
-
13
-
-
77957549861
-
Signaling Pathways in Renal Cell Carcinoma
-
Banumathy G, Cairns P: Signaling pathways in renal cell carcinoma. Cancer Biol Ther 2010; 10:658-664.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 658-664
-
-
Banumathy, G.1
Cairns, P.2
-
14
-
-
67651201656
-
Safety and efficacy of sunitinib for meta-static renal cell carcinoma: An expanded-ac-cess trial
-
Gore ME, Szczylik C, Porta C, Bracarda S, et al: Safety and efficacy of sunitinib for meta-static renal cell carcinoma: an expanded-ac-cess trial. La ncet Oncol 2009; 10: 757-763.
-
(2009)
La Ncet Oncol
, vol.10
, pp. 757-763
-
-
Gore, M.E.1
Szczylik, C.2
Porta, C.3
Bracarda, S.4
-
15
-
-
42249087301
-
A phase i pharmacokinetic and pharmacodynamic study of TKI258, an oral, multitargeted receptor tyrosine kinase inhibitor in patients with advanced solid tumors
-
Sarker D, Molife R, Evans TR, et al: A phase I pharmacokinetic and pharmacodynamic study of TKI258, an oral, multitargeted receptor tyrosine kinase inhibitor in patients with advanced solid tumors. Clin Cancer Res 2008; 14:2075-2081.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2075-2081
-
-
Sarker, D.1
Molife, R.2
Evans, T.R.3
-
16
-
-
84871019676
-
Tivan-tinib (ARQ 197) versus placebo in patients (Pts) with hepatocellular carcinoma (HCC) who failed one systemic therapy: Results of a randomized controlled phase II trial (RCT)
-
(abstract)
-
Rimassa L, Porta C, Borbath I, et al: Tivan-tinib (ARQ 197) versus placebo in patients (Pts) with hepatocellular carcinoma (HCC) who failed one systemic therapy: results of a randomized controlled phase II trial (RCT) (abstract). J Clin Oncol 2012; 30:4006.
-
(2012)
J Clin Oncol
, vol.30
, pp. 4006
-
-
Rimassa, L.1
Porta, C.2
Borbath, I.3
-
17
-
-
84867827863
-
Efficacy of cabozantinib (XL184) in patients (pts) with metastatic, refractory renal cell carcinoma (RCC)
-
(abstract)
-
Choueiri TK, Kumar Pal S, McDermott D, et al: Efficacy of cabozantinib (XL184) in patients (pts) with metastatic, refractory renal cell carcinoma (RCC) (abstract). J Clin Oncol 2012; 30:4504.
-
(2012)
J Clin Oncol
, vol.30
, pp. 4504
-
-
Choueiri, T.K.1
Kumar Pal, S.2
McDermott, D.3
-
18
-
-
77957995258
-
A phase I/II study of siltuximab (CNTO 328), an anti-interleukin6 monoclonal antibody, in meta-static renal cell cancer
-
Rossi JF, Négrier S, James ND, et al: A phase I/II study of siltuximab (CNTO 328), an anti-interleukin6 monoclonal antibody, in meta-static renal cell cancer. Br J Cancer 2010; 103: 1154-1162.
-
(2010)
Br J Cancer
, vol.103
, pp. 1154-1162
-
-
Rossi, J.F.1
Négrier, S.2
James, N.D.3
-
19
-
-
79953825469
-
Isimmuno-therapy Re-entering the Kidney Cancer Arena from the Back Door? Considerations from the Phase III Study of Siltuximab
-
Porta C, Pedrazzoli P, Paglino C: Isimmuno-therapy re-entering the kidney cancer arena from the back door? Considerations from the phase I/II study of siltuximab. Immunother-apy 2011; 3:487-490.
-
(2011)
Immunother-apy
, vol.3
, pp. 487-490
-
-
Porta, C.1
Pedrazzoli, P.2
Paglino, C.3
-
20
-
-
75749096309
-
Phase II trial of infusional fluorouracil, irinotecan and bevacizumab for metastatic colorectal cancer: Efficacy and circulating angiogenic biomarkers associated with therapeutic resistance
-
Kopetz S, Hoff PM, Morris JS, et al: Phase II trial of infusional fluorouracil, irinotecan and bevacizumab for metastatic colorectal cancer: efficacy and circulating angiogenic biomarkers associated with therapeutic resistance. J Clin Oncol 2010; 28:453-459.
-
(2010)
J Clin Oncol
, vol.28
, pp. 453-459
-
-
Kopetz, S.1
Hoff, P.M.2
Morris, J.S.3
-
21
-
-
26644471951
-
Drug resistance by evasion of antian-giogenic targeting of VEGF signaling in latestage pancreatic islet tumors
-
Casanovas O, Hicklin DJ, Bergers G, Hana-han D: Drug resistance by evasion of antian-giogenic targeting of VEGF signaling in latestage pancreatic islet tumors. Cancer Cell 2005; 8:299-309.
-
(2005)
Cancer Cell
, vol.8
, pp. 299-309
-
-
Casanovas, O.1
Hicklin, D.J.2
Bergers, G.3
Hana-Han, D.4
-
22
-
-
0034671392
-
Fibroblast growth factors are required for efficient tumor angiogenesis
-
Compagni A, Wilgenbus P, Impagnatiello MA, Cotten M, Christofori G: Fibroblast growth factors are required for efficient tumor angiogenesis. Cancer Res 2000; 60: 7163-7169.
-
(2000)
Cancer Res
, vol.60
, pp. 7163-7169
-
-
Compagni, A.1
Wilgenbus, P.2
Impagnatiello, M.A.3
Cotten, M.4
Christofori, G.5
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