The investigation of cushing syndrome: Essentials in optimizing appropriate diagnosis and management

Annals of Saudi Medicine

Volumn 32, Issue 5, 2012, Pages 455-461

  Juszczak, Agata ^a   Grossman, Ashley ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CHURCHILL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE; DEXAMETHASONE; DIAGNOSTIC AGENT; GLUCOCORTICOID;

ANAMNESIS; CLINICAL EXAMINATION; COMPUTER ASSISTED TOMOGRAPHY; CUSHING SYNDROME; DEXAMETHASONE SUPPRESSION TEST; HUMAN; HYDROCORTISONE URINE LEVEL; HYPERCORTISOLISM; INFERIOR PETROSAL SINUS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REVIEW; SALIVA LEVEL;

CUSHING SYNDROME; DEXAMETHASONE; GLUCOCORTICOIDS; HUMANS;

EID: 84868668274     PISSN: 02564947     EISSN: 09754466     Source Type: Journal    
DOI: 10.5144/0256-4947.2012.455     Document Type: Review

References (37)

1. Lindholm J, Juul S, Jorgensen JO, Astrup J, Bjerre P, Feldt-Rasmussen U, et al. Incidence and late prognosis of cushing's syndrome: a population- based study. J Clin Endocrinol Metab 2001; 86: 117-123.
2. Ross EJ, Linch DC. Cushing's syndrome-killing disease: discriminatory value of signs and symptoms aiding early diagnosis. Lancet 1982; 2: 646-649.
3. Nieman LK, Biller BM, Findling JW, Newell-Price J, Savage MO, Stewart PM, et al. The diagnosis of Cushing's syndrome: an Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab 2008; 93: 1526-1540.
4. Newell-Price J, Morris DG, Drake WM, Korbonits M, Monson JP, Besser GM, et al. Optimal response criteria for the human CRH test in the differential diagnosis of ACTH-dependent Cushing's syndrome. J Clin Endocrinol Metab 2002; 87: 1640-1645.
5. Alexandraki KI, Grossman AB. Is urinary free cortisol of value in the diagnosis of Cushing's syndrome? Curr Opin Endocrinol Diabetes Obes 2011;18: 259-263.
6. Kyriazopoulou V, Vagenakis AG. Abnormal overnight dexamethasone suppression test in subjects receiving rifampicin therapy. J Clin Endocrinol Metab 1992; 75: 315-317.
7. Meikle AW. Dexamethasone suppression tests: usefulness of simultaneous measurement of plasma cortisol and dexamethasone. Clin Endocrinol (Oxf) 1982;16:401-408.
8. Atkinson AB, McAteer EJ, Hadden DR, Kennedy L, Sheridan B, Traub AI. A weight-related intravenous dexamethasone suppression test distinguishes obese controls from patients with Cushing's syndrome. Acta Endocrinol (Copenh) 1989;120:753-759.
9. Newell-Price J, Trainer P, Besser M, Grossman A. The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states. Endocr Rev 1998;19:647-672.
10. Kahn JP, Rubinow DR, Davis CL, Kling M, Post RM. Salivary cortisol: a practical method for evaluation of adrenal function. Biol Psychiatry 1988;23:335-349.
11. Viardot A, Huber P, Puder JJ, Zulewski H, Keller U, Muller B. Reproducibility of nighttime salivary cortisol and its use in the diagnosis of hypercortisolism compared with urinary free cortisol and overnight dexamethasone suppression test. J Clin Endocrinol Metab 2005;90:5730-5736.
12. Alexandraki KI & Grossman AB. Novel insights in the diagnosis of Cushing's syndrome. Neuroendocrinology 2010; 92: Suppl 1 35-43.
13. Cardoso EM, Arregger AL, Tumilasci OR, Contreras LN. Diagnostic value of salivary cortisol in Cushing's syndrome (CS). Clin Endocrinol (Oxf) 2009;70:516-521.
14. Carroll T, Raff H, Findling JW. Late-Night Salivary Cortisol for the Diagnosis of Cushing's Syndrome: A Meta-Analysis. Endocr Pract 2009;1-17.
15. Martinelli CE Jr., Sader SL, Oliveira EB, Daneluzzi JC, Moreira AC. Salivary cortisol for screening of Cushing's syndrome in children. Clin Endocrinol (Oxf) 1999;51: 67-71.
16. Contreras LN, Hane S, Tyrrell JB. Urinary cortisol in the assessment of pituitary-adrenal function: utility of 24-hour and spot determinations. J Clin Endocrinol Metab 1986;62:965-969.
17. Mericq MV, Cutler GB Jr. High fluid intake increases urine free cortisol excretion in normal subjects. J Clin Endocrinol Metab 1998;83:682-684.
18. Yanovski JA, Cutler GB Jr., Chrousos GP, Nieman LK. Corticotropin- releasing hormone stimulation following low-dose dexamethasone administration. A new test to distinguish Cushing's syndrome from pseudo-Cushing's states. JAMA 1993;269: 2232-2238.
19. Grossman AB, Howlett TA, Perry L, Coy DH, Savage MO, Lavender P, et al. CR F in the differential diagnosis of Cushing's syndrome: a comparison with the dexamethasone suppression test. Clin Endocrinol (Oxf) 1988;29:167-178.
20. Newell-Price J, Grossman AB. Differential diagnosis of Cushing's syndrome. Arq Bras Endocrinol Metabol 2007;51:1199-1206.
21. Buchfelder M, Nistor R, Fahlbusch R, Huk WJ. The accuracy of CT and MR evaluation of the sella turcica for detection of adrenocorticotropic hormone- secreting adenomas in Cushing disease. Am J Neuroradiol 1993;14: 1183-1190.
22. Peck WW, Dillon WP, Norman D, Newton TH, Wilson CB. High-resolution MR imaging of pituitary microadenomas at 1.5 T: experience with Cushing disease. Am J Roentgenol 1989;152:145- 151.
23. Buurman H, Saeger W. Subclinical adenomas in postmortem pituitaries: classification and correlations to clinical data. Eur J Endocrinol 2006;154: 753-758.
24. Findling JW, Doppman JL. Biochemical and radiologic diagnosis of Cushing's syndrome. Endocrinol Metab Clin North Am 1994;23: 511-537.
25. Sohaib SA, Hanson JA, Newell-Price JD, Trainer PJ, Monson JP, Grossman AB, et al. CT appearance of the adrenal glands in adrenocorticotrophic hormone-dependent Cushing's syndrome. Am J Roentgenol 1999;172: 997-1002.
26. Slattery JM, Blake MA, Kalra MK, Misdraji J, Sweeney AT, Copeland PM, et al. Adrenocortical carcinoma: contrast washout characteristics on CT. Am J Roentgenol 2006;187:W21-W24.
27. Rockall AG, Sohaib SA, Evans D, Kaltsas G, Isidori AM, Monson JP, et al. Computed tomography assessment of fat distribution in male and female patients with Cushing's syndrome. Eur J Endocrinol 2003;149:561-567.
28. Sahdev A, Reznek RH, Evanson J, Grossman AB. Imaging in Cushing's syndrome. Arq Bras Endocrinol Metabol 2007;51:1319-1328.
29. Vincent JM, Trainer PJ, Reznek RH, Marcus AJ, Dacie JE, Armstrong P, et al. The radiological investigation of occult ectopic ACTH-dependent Cushing's syndrome. Clin Radiol 1993;48:11-17.
30. Ilias I, Torpy DJ, Pacak K, Mullen N, Wesley RA, Nieman LK. Cushing's syndrome due to ectopic corticotropin secretion: twenty years' experience at the National Institutes of Health. J Clin Endocrinol Metab 2005;90:4955-4962.
31. Isidori AM, Kaltsas GA, Mohammed S, Morris DG, Jenkins P, Chew SL, et al. Discriminatory value of the low-dose dexamethasone suppression test in establishing the diagnosis and differential diagnosis of Cushing's syndrome. J Clin Endocrinol Metab 2003;88:5299-5306.
32. Howlett TA, Drury PL, Perry L, Doniach I, Rees LH, Besser GM. Diagnosis and management of ACTH-dependent Cushing's syndrome: comparison of the features in ectopic and pituitary ACTH production. Clin Endocrinol (Oxf) 1986;24:699-713.
33. Stewart PM, Whorwood CB. 11 beta-Hydroxysteroid dehydrogenase activity and corticosteroid hormone action. Steroids 1994;59:90-95.
34. Oldfield EH, Doppman JL, Nieman LK, Chrousos GP, Miller DL, Katz DA, et al. Petrosal sinus sampling with and without corticotropin-releasing hormone for the differential diagnosis of Cushing's syndrome. N Engl J Med 1991;325:897-905.
35. Kaltsas GA, Giannulis MG, Newell-Price JD, Dacie JE, Thakkar C, Afshar F, et al. A critical analysis of the value of simultaneous inferior petrosal sinus sampling in Cushing's disease and the occult ectopic adrenocorticotropin syndrome. J Clin Endocrinol Metab 1999;84:487-492.
36. Lienhardt A, Grossman AB, Dacie JE, Evanson J, Huebner A, Afshar F, et al. Relative contributions of inferior petrosal sinus sampling and pituitary imaging in the investigation of children and adolescents with ACTH-dependent Cushing's syndrome. J Clin Endocrinol Metab 2001;86:5711- 5714.
37. Mamelak AN, Dowd CF, Tyrrell JB, McDonald JF, Wilson CB. Venous angiography is needed to interpret inferior petrosal sinus and cavernous sinus sampling data for lateralizing adrenocorticotropin- secreting adenomas. J Clin Endocrinol Metab 1996;81:475-481.