-
1
-
-
35448958119
-
A vision of individualized medicine in the context of global health
-
Cortese, D.A. A vision of individualized medicine in the context of global health. Clin. Pharmacol. Ther. 82, 491-493 (2007).
-
(2007)
Clin. Pharmacol. Ther
, vol.82
, pp. 491-493
-
-
Cortese, D.A.1
-
2
-
-
18344385481
-
Autoantigen microarrays for multiplex characterization of autoantibody responses
-
Robinson, W.H. et al. Autoantigen microarrays for multiplex characterization of autoantibody responses. Nat. Med. 8, 295-301 (2002).
-
(2002)
Nat. Med
, vol.8
, pp. 295-301
-
-
Robinson, W.H.1
-
3
-
-
10744231057
-
Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis
-
Robinson, W.H. et al. Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis. Nat. Biotechnol. 21, 1033-1039 (2003).
-
(2003)
Nat. Biotechnol
, vol.21
, pp. 1033-1039
-
-
Robinson, W.H.1
-
4
-
-
0141565124
-
Microarray profiling of antibody responses against simian-human immunodeficiency virus: Postchallenge convergence of reactivities independent of host histocompatibility type and vaccine regimen
-
Neuman de Vegvar, H.E. et al. Microarray profiling of antibody responses against simian-human immunodeficiency virus: postchallenge convergence of reactivities independent of host histocompatibility type and vaccine regimen. J. Virol. 77, 11125-11138 (2003).
-
(2003)
J. Virol
, vol.77
, pp. 11125-11138
-
-
Neuman De Vegvar, H.E.1
-
5
-
-
11144256544
-
Protein microarrays for multiplex analysis of signal transduction pathways
-
Chan, S.M., Ermann, J., Su, L., Fathman, C.G. & Utz, P.J. Protein microarrays for multiplex analysis of signal transduction pathways. Nat. Med. 10, 1390-1396 (2004).
-
(2004)
Nat. Med
, vol.10
, pp. 1390-1396
-
-
Chan, S.M.1
Ermann, J.2
Su, L.3
Fathman, C.G.4
Utz, P.J.5
-
6
-
-
55549099552
-
HIT a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular proteins and surface molecules
-
Kattah, M.G., Coller, J., Cheung, R.K., Oshidary, N. & Utz, P.J. HIT: a versatile proteomics platform for multianalyte phenotyping of cytokines, intracellular proteins and surface molecules. Nat. Med. 14, 1284-1289 (2008).
-
(2008)
Nat. Med
, vol.14
, pp. 1284-1289
-
-
Kattah, M.G.1
Coller, J.2
Cheung, R.K.3
Oshidary, N.4
Utz, P.J.5
-
7
-
-
17844386055
-
Antibody arrays in cancer research
-
Haab, B.B. Antibody arrays in cancer research. Mol. Cell. Proteomics 4, 377-383 (2005).
-
(2005)
Mol. Cell. Proteomics
, vol.4
, pp. 377-383
-
-
Haab, B.B.1
-
8
-
-
35948933394
-
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
-
Ray, S. et al. Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins. Nat. Med. 13, 1359-1362 (2007).
-
(2007)
Nat. Med
, vol.13
, pp. 1359-1362
-
-
Ray, S.1
-
9
-
-
67749122581
-
Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease
-
Britschgi, M. et al. Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. Proc. Natl. Acad. Sci. USA 106, 12145-12150 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12145-12150
-
-
Britschgi, M.1
-
10
-
-
77956320456
-
A protein allergen microarray detects specific IgE to pollen surface, cytoplasmic, and commercial allergen extracts
-
Vigh-Conrad, K.A., Conrad, D.F. & Preuss, D. A protein allergen microarray detects specific IgE to pollen surface, cytoplasmic, and commercial allergen extracts. PLoS ONE 5, e10174 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Vigh-Conrad, K.A.1
Conrad, D.F.2
Preuss, D.3
-
11
-
-
78649248200
-
Grand challenge commentary: Informative diagnostics for personalized medicine
-
Bailey, R.C. Grand challenge commentary: informative diagnostics for personalized medicine. Nat. Chem. Biol. 6, 857-859 (2010).
-
(2010)
Nat. Chem. Biol
, vol.6
, pp. 857-859
-
-
Bailey, R.C.1
-
12
-
-
0026108692
-
Light-directed, spatially addressable parallel chemical synthesis
-
Fodor, S.P. et al. Light-directed, spatially addressable parallel chemical synthesis. Science 251, 767-773 (1991).
-
(1991)
Science
, vol.251
, pp. 767-773
-
-
Fodor, S.P.1
-
13
-
-
0242440033
-
Light directed massively parallel on-chip synthesis of peptide arrays with t-Boc chemistry
-
Gao, X., Zhou, X. & Gulari, E. Light directed massively parallel on-chip synthesis of peptide arrays with t-Boc chemistry. Proteomics 3, 2135-2141 (2003).
-
(2003)
Proteomics
, vol.3
, pp. 2135-2141
-
-
Gao, X.1
Zhou, X.2
Gulari, E.3
-
14
-
-
77954555140
-
Automated maskless photolithography system for peptide microarray synthesis on a chip
-
Shin, D.S. et al. Automated maskless photolithography system for peptide microarray synthesis on a chip. J. Comb. Chem. 12, 463-471 (2010).
-
(2010)
J. Comb. Chem
, vol.12
, pp. 463-471
-
-
Shin, D.S.1
-
15
-
-
0842324785
-
The nucleosome: From genomic organization to genomic regulation
-
Khorasanizadeh, S. The nucleosome: from genomic organization to genomic regulation. Cell 116, 259-272 (2004).
-
(2004)
Cell
, vol.116
, pp. 259-272
-
-
Khorasanizadeh, S.1
-
16
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides, T. Chromatin modifications and their function. Cell 128, 693-705 (2007).
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
17
-
-
0034607631
-
Molecular and structural properties of three autoimmune IgG monoclonal antibodies to histone H2B
-
Monestier, M., Decker, P., Briand, J.P., Gabriel, J.L. & Muller, S. Molecular and structural properties of three autoimmune IgG monoclonal antibodies to histone H2B. J. Biol. Chem. 275, 13558-13563 (2000).
-
(2000)
J. Biol. Chem
, vol.275
, pp. 13558-13563
-
-
Monestier, M.1
Decker, P.2
Briand, J.P.3
Gabriel, J.L.4
Muller, S.5
-
18
-
-
70450222929
-
Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies
-
van Bavel, C.C. et al. Apoptosis-associated acetylation on histone H2B is an epitope for lupus autoantibodies. Mol. Immunol. 47, 511-516 (2009).
-
(2009)
Mol. Immunol
, vol.47
, pp. 511-516
-
-
Van Bavel, C.C.1
-
19
-
-
0034839588
-
Photolithographic synthesis of high-density oligonucleotide probe arrays
-
Barone, A.D. et al. Photolithographic synthesis of high-density oligonucleotide probe arrays. Nucleosides Nucleotides Nucleic Acids 20, 525-531 (2001).
-
(2001)
Nucleosides Nucleotides Nucleic Acids
, vol.20
, pp. 525-531
-
-
Barone, A.D.1
-
20
-
-
0033128171
-
LC/MS applications in drug development
-
Lee, M.S. & Kerns, E.H. LC/MS applications in drug development. Mass Spectrom. Rev. 18, 187-279 (1999).
-
(1999)
Mass Spectrom. Rev
, vol.18
, pp. 187-279
-
-
Lee, M.S.1
Kerns, E.H.2
-
21
-
-
79251590753
-
Specificity analysis-based identification of new methylation targets of the SET7/9 protein lysine methyltransferase
-
Dhayalan, A., Kudithipudi, S., Rathert, P. & Jeltsch, A. Specificity analysis-based identification of new methylation targets of the SET7/9 protein lysine methyltransferase. Chem. Biol. 18, 111-120 (2011).
-
(2011)
Chem. Biol
, vol.18
, pp. 111-120
-
-
Dhayalan, A.1
Kudithipudi, S.2
Rathert, P.3
Jeltsch, A.4
-
22
-
-
0038293152
-
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase
-
Cheung, W.L. et al. Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell 113, 507-517 (2003).
-
(2003)
Cell
, vol.113
, pp. 507-517
-
-
Cheung, W.L.1
-
23
-
-
0028922074
-
Autoantibodies in the diagnosis of systemic rheumatic diseases
-
von Mühlen, C.A. & Tan, E.M. Autoantibodies in the diagnosis of systemic rheumatic diseases. Semin. Arthritis Rheum. 24, 323-358 (1995).
-
(1995)
Semin. Arthritis Rheum
, vol.24
, pp. 323-358
-
-
Von Mühlen, C.A.1
Tan, E.M.2
-
24
-
-
0344492212
-
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
-
Baechler, E.C. et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc. Natl. Acad. Sci. USA 100, 2610-2615 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2610-2615
-
-
Baechler, E.C.1
-
25
-
-
33845877145
-
Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus
-
Bauer, J.W. et al. Elevated serum levels of interferon-regulated chemokines are biomarkers for active human systemic lupus erythematosus. PLoS Med. 3, e491 (2006).
-
(2006)
PLoS Med
, vol.3
-
-
Bauer, J.W.1
-
26
-
-
77955545859
-
The interferon-α signature of systemic lupus erythematosus
-
Obermoser, G. & Pascual, V. The interferon-α signature of systemic lupus erythematosus. Lupus 19, 1012-1019 (2010).
-
(2010)
Lupus
, vol.19
, pp. 1012-1019
-
-
Obermoser, G.1
Pascual, V.2
-
27
-
-
34447523785
-
Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus
-
Dieker, J.W. et al. Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus. Arthritis Rheum. 56, 1921-1933 (2007).
-
(2007)
Arthritis Rheum
, vol.56
, pp. 1921-1933
-
-
Dieker, J.W.1
-
28
-
-
77957942335
-
Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus
-
van Bavel, C.C. et al. Apoptosis-induced histone H3 methylation is targeted by autoantibodies in systemic lupus erythematosus. Ann. Rheum. Dis. 70, 201-207 (2011).
-
(2011)
Ann. Rheum. Dis
, vol.70
, pp. 201-207
-
-
Van Bavel, C.C.1
-
29
-
-
0034087160
-
Hopkins Lupus Cohort 1999 update Rheum
-
Petri, M. Hopkins Lupus Cohort. 1999 update. Rheum. Dis. Clin. North Am. 26, 199-213, 5 (2000).
-
(2000)
Dis. Clin. North Am
, vol.26
, Issue.5
, pp. 199-213
-
-
Petri, M.1
-
30
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher, V.G., Tibshirani, R. & Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98, 5116-5121 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
31
-
-
27144457668
-
Upping the ante on antibodies
-
Baker, M. Upping the ante on antibodies. Nat. Biotechnol. 23, 1065-1072 (2005).
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 1065-1072
-
-
Baker, M.1
-
32
-
-
78650308842
-
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling
-
Levy, D. et al. Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling. Nat. Immunol. 12, 29-36 (2011).
-
(2011)
Nat. Immunol
, vol.12
, pp. 29-36
-
-
Levy, D.1
-
33
-
-
33644856123
-
Epigenetic therapy of cancer: Past, present and future
-
Yoo, C.B. & Jones, P.A. Epigenetic therapy of cancer: past, present and future. Nat. Rev. Drug Discov. 5, 37-50 (2006).
-
(2006)
Nat. Rev. Drug Discov
, vol.5
, pp. 37-50
-
-
Yoo, C.B.1
Jones, P.A.2
-
34
-
-
77649316480
-
Deamidated gliadin peptide antibodies as a routine test for celiac disease: A prospective analysis
-
Volta, U. et al. Deamidated gliadin peptide antibodies as a routine test for celiac disease: a prospective analysis. J. Clin. Gastroenterol. 44, 186-190 (2010).
-
(2010)
J. Clin. Gastroenterol
, vol.44
, pp. 186-190
-
-
Volta, U.1
-
35
-
-
0042386360
-
Clinical utility of the anti-CCP assay in patients with rheumatic diseases
-
Lee, D.M. & Schur, P.H. Clinical utility of the anti-CCP assay in patients with rheumatic diseases. Ann. Rheum. Dis. 62, 870-874 (2003).
-
(2003)
Ann. Rheum. Dis
, vol.62
, pp. 870-874
-
-
Lee, D.M.1
Schur, P.H.2
-
36
-
-
19944366229
-
Diagnostic performance and predictive value of rheumatoid factor, anti-citrullinated peptide antibodies, and the HLA shared epitope for diagnosis of rheumatoid arthritis
-
Hoffman, I.E. et al. Diagnostic performance and predictive value of rheumatoid factor, anti-citrullinated peptide antibodies, and the HLA shared epitope for diagnosis of rheumatoid arthritis. Clin. Chem. 51, 261-263 (2005).
-
(2005)
Clin. Chem
, vol.51
, pp. 261-263
-
-
Hoffman, I.E.1
-
37
-
-
44849103664
-
Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis
-
Garren, H. et al. Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis. Ann. Neurol. 63, 611-620 (2008).
-
(2008)
Ann. Neurol
, vol.63
, pp. 611-620
-
-
Garren, H.1
-
38
-
-
79960587086
-
Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics
-
Liskamp, R.M.J., Rijkers, D.T.S., Kruijtzer, J.A.W. & Kemmink, J. Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics. ChemBioChem 12, 1626-1653 (2011).
-
(2011)
Chem Bio Chem
, vol.12
, pp. 1626-1653
-
-
Liskamp, R.M.J.1
Rijkers, D.T.S.2
Kruijtzer, J.A.W.3
Kemmink, J.4
-
39
-
-
79952265731
-
NanoLAB: An ultraportable, handheld diagnostic laboratory for global health
-
Gaster, R.S., Hall, D.A. & Wang, S.X. nanoLAB: an ultraportable, handheld diagnostic laboratory for global health. Lab Chip 11, 950-956 (2011).
-
(2011)
Lab Chip
, vol.11
, pp. 950-956
-
-
Gaster, R.S.1
Hall, D.A.2
Wang, S.X.3
|