Anti-inflammatory effects of isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate, a novel metabolite from Danshen, on activated microglia

Chinese Journal of Physiology

Volumn 55, Issue 6, 2012, Pages 428-434

  Wang, Shaoxia ^a   Wang, Hong ^a   Jing, Haoran ^a   Wang, Shixiang ^b   Kang, Liyuan ^a   Gao, Xiumei ^a   Hu, Limin ^a   Zheng, Xiaohui ^b  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b NORTHWEST UNIVERSITY   (China)

Author keywords

4 dihydroxyphenyl) 2 hydroxypropanoate; Inflammation; Isopropyl 3 (3; Meuroprotection; Microglia

Indexed keywords

ANTIINFLAMMATORY AGENT; CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; ISOPROPYL 3 (3,4 DIHYDROXYPHENYL) 2 HYDROXYPROPANOATE; MESSENGER RNA; NITRIC OXIDE; NITRITE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; LIPOPOLYSACCHARIDE;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; DNA BINDING; DRUG EFFECT; DRUG STRUCTURE; GENE; GENE EXPRESSION REGULATION; GENE REPRESSION; INDUCIBLE NITRIC OXIDE SYNTHASE GENE; INTERLEUKIN 1BETA GENE; METABOLITE; MICROGLIA; MOUSE; NONHUMAN; PRIMARY CELL CULTURE; PROTEIN TRANSPORT; RAT; SALVIA MILTIORRHIZA; TUMOR NECROSIS FACTOR ALPHA GENE; ANIMAL; METABOLISM;

ANIMALS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MICROGLIA; NF-KAPPA B; NITRIC OXIDE; SALVIA MILTIORRHIZA;

EID: 84868665453     PISSN: 03044920     EISSN: 26660059     Source Type: Journal    
DOI: 10.4077/CJP.2012.BAA045     Document Type: Article

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