A novel microphysiometer based on high sensitivity LAPS and microfluidic system for cellular metabolism study and rapid drug screening

Biosensors and Bioelectronics

Volumn 40, Issue 1, 2013, Pages 167-173

  Hu, Ning ^a   Wu, Chengxiong ^a   Ha, Da ^a   Wang, Tianxing ^b   Liu, Qingjun ^a   Wang, Ping ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b West Lake Technology and Economy Park   (China)

Author keywords

Cellular metabolism; Drug screening; Microfluidic system; Microphysiometer

Indexed keywords

CELLULAR METABOLISM; CHARACTERISTIC TEST; CONCENTRATION CHANGE; CONSTANT CURRENT MODE; CONSTANT VOLTAGE; DETECTION SENSITIVITY; DRUG EFFECTS; DRUG SCREENING; EXTRACELLULAR; FABRICATION PROCESS; FEEDBACK RATES; HIGH SENSITIVITY; LIGHT ADDRESSABLE POTENTIOMETRIC SENSORS; LIVING CELL; MICRO FLUIDIC SYSTEM; MICROENVIRONMENTS; MICROPHYSIOMETER; PHOTOCURRENT AMPLIFICATION; PHYSIOLOGICAL CONDITION; RAPID DRUG-SCREENING; REAL-TIME DETECTION; SENSOR STRUCTURES; SENSOR UNITS;

AMPLIFICATION; AUTOMOBILE MANUFACTURE; ENZYME ACTIVITY; EXPERIMENTS; FLUIDIC DEVICES;

POTENTIOMETRIC SENSORS;

ARTICLE; BIOSENSOR; CELL METABOLISM; CELL PH; CELL STRAIN MCF 7; DRUG SCREENING; HUMAN; HUMAN CELL; LABORATORY DEVICE; MICROFLUIDIC ANALYSIS; MICROPHYSIOMETER; SENSITIVITY AND SPECIFICITY;

BIOSENSING TECHNIQUES; CONDUCTOMETRY; DRUG EVALUATION, PRECLINICAL; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; HUMANS; MCF-7 CELLS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MINIATURIZATION; NEOPLASMS, EXPERIMENTAL; PHOTOMETRY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 84868633149     PISSN: 09565663     EISSN: 18734235     Source Type: Journal    
DOI: 10.1016/j.bios.2012.07.010     Document Type: Article

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