Mitochondrial base excision repair assays

Methods in Molecular Biology

Volumn 920, Issue , 2012, Pages 289-304

  Gredilla, Ricardo ^b   Stevnsner, Tinna ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^b AARHUS UNIVERSITY   (Denmark)

Author keywords

Base excision repair; DNA repair; Mitochondria; MtDNA

Indexed keywords

EID: 84868591177     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-998-3_20     Document Type: Article

References (21)

1. Grollman AP, Moriya M (1993) Mutagenesis by 8-oxoguanine: an enemy within. Trends Genet 9: 246-249 (Pubitemid 23188487)
2. Kavli B, Otterlei M, Slupphaug G, Krokan HE (2007) Uracil in DNA\general mutagen, but normal intermediate in acquired immunity. DNA Repair (Amst) 6: 505-516 (Pubitemid 46357053)
3. Croteau DL, Bohr VA (1997) Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells. J Biol Chem 272: 25409-25412 (Pubitemid 27438839)
4. Hamilton ML, Guo Z, Fuller CD, Van Remmen H, Ward WF, Austad SN, Troyer DA, Thompson I, Richardson A (2001) A reliable assessment of 8-oxo-2-deoxyguanosine levels in nuclear and mitochondrial DNA using the sodium iodide method to isolate DNA. Nucleic Acids Res 29: 2117-2126 (Pubitemid 32472082)
5. Barja G, Herrero A (2000) Oxidative damage to mitochondrial DNA is inversely related to maximum life span in the heart and brain of mammals. FASEB J 14: 312-318 (Pubitemid 30086068)
6. Schon EA (2000) Mitochondrial genetics and disease. Trends Biochem Sci 25: 555-560
7. Beal MF (2005) Mitochondria take center stage in aging and neurodegeneration. Ann Neurol 58: 495-505 (Pubitemid 41377212)
8. Melov S (2004) Modeling mitochondrial function in aging neurons. Trends Neurosci 27: 601-606 (Pubitemid 39221396)
9. Krishnan KJ, Reeve AK, Samuels DC, Chinnery PF, Blackwood JK, Taylor RW, Wanrooij S, Spelbrink JN, Lightowlers RN, Turnbull DM (2008) What causes mitochondrial DNA deletions in human cells? Nat Genet 40: 275-279 (Pubitemid 351311775)
10. Weissman L, de Souza-Pinto NC, Stevnsner T, Bohr VA (2007) DNA repair, mitochondria, and neurodegeneration. Neuroscience 145: 1318-1329 (Pubitemid 46602727)
11. Gredilla R, Bohr VA, Stevnsner T (2010) Mitochondrial DNA repair and association with aging\an update. Exp Gerontol 45: 478-488
12. Seeberg E, Eide L, Bjoras M (1995) The base excision repair pathway. Trends Biochem Sci 20: 391-397
13. Bohr VA (2002) DNA damage and its processing. Relation to human disease. J Inherit Metab Dis 25: 215-222 (Pubitemid 34700312)
14. Bohr VA (2002) Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells. Free Radic Biol Med 32: 804-812 (Pubitemid 34439251)
15. Stuart JA, Karahalil B, Hogue BA, Souza-Pinto NC, Bohr VA (2004) Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction. FASEB J 18: 595-597
16. Karahalil B, Hogue BA, de Souza-Pinto NC, Bohr VA (2002) Base excision repair capacity in mitochondria and nuclei: tissue-specific variations. FASEB J 16: 1895-1902 (Pubitemid 35462609)
17. Lai JC, Clark JB (1979) Preparation of synaptic and nonsynaptic mitochondria from mammalian brain. Methods Enzymol 55: 51-60
18. Kristian T, Hopkins IB, McKenna MC, Fiskum G (2006) Isolation of mitochondria with high respiratory control from primary cultures of neurons and astrocytes using nitrogen cavita-tion. J Neurosci Methods 152: 136-143 (Pubitemid 43343484)
19. 2+ overload than nonsynaptic mitochondria. J Biol Chem 281: 11658-11668 (Pubitemid 43855423)
20. Schrimpf SP, Meskenaite V, Brunner E, Rutishauser D, Walther P, Eng J, Aebersold R, Sonderegger P (2005) Proteomic analysis of synaptosomes using isotope-coded affinity tags and mass spectrometry. Proteomics 5: 2531-2541 (Pubitemid 40966480)
21. Gredilla R, Weissman L, Yang JL, Bohr VA, Stevnsner T (2010) Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease. Neurobiol Aging 33(4): 694-707