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Volumn 900, Issue , 2012, Pages 25-60

Methods and protocols to study T cell signaling abnormalities in human systemic lupus erythematosus

Author keywords

Autoimmune disease; Calcium response; CD3 ; Cell proliferation; Cell signaling; Cytokines; Immunoblotting; Systemic lupus erythematosus; T cell isolation; T cell receptor; Tyrosine phosphorylation

Indexed keywords


EID: 84868581258     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60761-720-4_3     Document Type: Article
Times cited : (2)

References (24)
  • 1
    • 0027399703 scopus 로고
    • Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain
    • Irving BA, Chan AC, Weiss A (1993) Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. J Exp Med 177:1093-1103
    • (1993) J Exp Med , vol.177 , pp. 1093-1103
    • Irving, B.A.1    Chan, A.C.2    Weiss, A.3
  • 2
    • 0029776828 scopus 로고    scopus 로고
    • Differential and multiple binding of signal transducing molecules to the ITAMs of the TCR-zeta chain
    • Zenner G, Vorherr T, Mustelin T, Burn P (1996) Differential and multiple binding of signal transducing molecules to the ITAMs of the TCR-zeta chain. J Cell Biochem 63:94-103
    • (1996) J Cell Biochem , vol.63 , pp. 94-103
    • Zenner, G.1    Vorherr, T.2    Mustelin, T.3    Burn, P.4
  • 3
    • 0032563231 scopus 로고    scopus 로고
    • Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation
    • Kersh EN, Shaw AS, Allen PM (1998) Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation. Science (N Y) 281:572-575
    • (1998) Science (N Y , vol.281 , pp. 572-575
    • Kersh, E.N.1    Shaw, A.S.2    Allen, P.M.3
  • 4
    • 0033404953 scopus 로고    scopus 로고
    • Partially phosphorylated T cell receptor zeta molecules can inhibit T cell activation
    • Kersh EN, Kersh GJ, Allen PM (1999) Partially phosphorylated T cell receptor zeta molecules can inhibit T cell activation. J Exp Med 190:1627-1636
    • (1999) J Exp Med , vol.190 , pp. 1627-1636
    • Kersh, E.N.1    Kersh, G.J.2    Allen, P.M.3
  • 5
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss A, Littman DR (1994) Signal transduction by lymphocyte antigen receptors. Cell 76:263-274
    • (1994) Cell , vol.76 , pp. 263-274
    • Weiss, A.1    Littman, D.R.2
  • 6
    • 0030250114 scopus 로고    scopus 로고
    • Complex complexes: Signaling at the TCR
    • Wange RL, Samelson LE (1996) Complex complexes: Signaling at the TCR. Immunity 5:197-205
    • (1996) Immunity , vol.5 , pp. 197-205
    • Wange, R.L.1    Samelson, L.E.2
  • 8
    • 0031840785 scopus 로고    scopus 로고
    • TCR zeta chain lacking exon 7 in two patients with systemic lupus erythematosus
    • Takeuchi T, Tsuzaka K, Pang M, Amano K, Koide J, Abe T (1998) TCR zeta chain lacking exon 7 in two patients with systemic lupus erythematosus. Int Immunol 10:911-921
    • (1998) Int Immunol , vol.10 , pp. 911-921
    • Takeuchi, T.1    Tsuzaka, K.2    Pang, M.3    Amano, K.4    Koide, J.5    Abe, T.6
  • 9
    • 77951234994 scopus 로고    scopus 로고
    • Alternative splicing factor/splicing factor 2 regulates the expression of the zeta subunit of the human T cell receptor-Associated CD3 complex
    • Moulton VR, Tsokos GC (2010) Alternative splicing factor/splicing factor 2 regulates the expression of the zeta subunit of the human T cell receptor-Associated CD3 complex. J Biol Chem 285:12490-12496
    • (2010) J Biol Chem , vol.285 , pp. 12490-12496
    • Moulton, V.R.1    Tsokos, G.C.2
  • 10
    • 50649124254 scopus 로고    scopus 로고
    • The RNAstabilizing protein HuR regulates the expression of zeta chain of the human T cell receptor-Associated CD3 complex
    • Moulton VR, Kyttaris VC, Juang YT, Chowdhury B, Tsokos GC (2008) The RNAstabilizing protein HuR regulates the expression of zeta chain of the human T cell receptor-Associated CD3 complex. J Biol Chem 283:20037-20044
    • (2008) J Biol Chem , vol.283 , pp. 20037-20044
    • Moulton, V.R.1    Kyttaris, V.C.2    Juang, Y.T.3    Chowdhury, B.4    Tsokos, G.C.5
  • 11
    • 0032036481 scopus 로고    scopus 로고
    • Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. De fi cient expression of the T cell receptor zeta chain
    • Liossis SN, Ding XZ, Dennis GJ, Tsokos GC (1998) Altered pattern of TCR/CD3-mediated protein-tyrosyl phosphorylation in T cells from patients with systemic lupus erythematosus. De fi cient expression of the T cell receptor zeta chain. J Clin Invest 101:1448-1457
    • (1998) J Clin Invest , vol.101 , pp. 1448-1457
    • Liossis, S.N.1    Ding, X.Z.2    Dennis, G.J.3    Tsokos, G.C.4
  • 12
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 13
    • 0020055601 scopus 로고
    • Mitogenic responses to lipopolysaccharide by B lymphocytes from patients with systemic lupus erythematosus
    • Abe T, Toguchi T, Takeuchi T, Kiyotaki M, Homma M (1981) Mitogenic responses to lipopolysaccharide by B lymphocytes from patients with systemic lupus erythematosus. Scand J Immunol 15:475-482
    • (1981) Scand J Immunol , vol.15 , pp. 475-482
    • Abe, T.1    Toguchi, T.2    Takeuchi, T.3    Kiyotaki, M.4    Homma, M.5
  • 14
    • 0037141091 scopus 로고    scopus 로고
    • Surface cytotoxic T lymphocyte-Associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition of T cell activation
    • Darlington PJ, Baroja ML, Chau TA, Siu E, Ling V, Carreno BM, Madrenas J (2002) Surface cytotoxic T lymphocyte-Associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition of T cell activation. J Exp Med 195:1337-1347
    • (2002) J Exp Med , vol.195 , pp. 1337-1347
    • Darlington, P.J.1    Baroja, M.L.2    Chau, T.A.3    Siu, E.4    Ling, V.5    Carreno, B.M.6    Madrenas, J.7
  • 15
    • 0032101348 scopus 로고    scopus 로고
    • Membrane compartmentation is required for ef fi cient T cell activation
    • Xavier R, Brennan T, Li Q, McCormack C, Seed B (1998) Membrane compartmentation is required for ef fi cient T cell activation. Immunity 8:723-732
    • (1998) Immunity , vol.8 , pp. 723-732
    • Xavier, R.1    Brennan, T.2    Li, Q.3    McCormack, C.4    Seed, B.5
  • 16
    • 0036264363 scopus 로고    scopus 로고
    • Direct transfer of p65 into T lymphocytes from systemic lupus erythematosus patients leads to increased levels of interleukin-2 promoter activity
    • Herndon TM, Juang YT, Solomou EE, Rothwell SW, Gourley MF, Tsokos GC (2002) Direct transfer of p65 into T lymphocytes from systemic lupus erythematosus patients leads to increased levels of interleukin-2 promoter activity. Clin Immunol 103:145-153
    • (2002) Clin Immunol , vol.103 , pp. 145-153
    • Herndon, T.M.1    Juang, Y.T.2    Solomou, E.E.3    Rothwell, S.W.4    Gourley, M.F.5    Tsokos, G.C.6
  • 17
    • 0037443553 scopus 로고    scopus 로고
    • Forced expression of the Fc receptor gamma-Chain renders human T cells hyperresponsive to TCR/CD3 stimulation
    • Nambiar MP, Fisher CU, Kumar A, Tsokos CG, Warke VG, Tsokos GC (2003) Forced expression of the Fc receptor gamma-Chain renders human T cells hyperresponsive to TCR/CD3 stimulation. J Immunol 170:2871-2876
    • (2003) J Immunol , vol.170 , pp. 2871-2876
    • Nambiar, M.P.1    Fisher, C.U.2    Kumar, A.3    Tsokos, C.G.4    Warke, V.G.5    Tsokos, G.C.6
  • 21
    • 0029809142 scopus 로고    scopus 로고
    • Normal T cells express two T cell antigen receptor populations, One of which is linked to the cytoskeleton via zeta chain and displays a unique activationdependent phosphorylation pattern
    • Caplan S, Baniyash M (1996) Normal T cells express two T cell antigen receptor populations, One of which is linked to the cytoskeleton via zeta chain and displays a unique activationdependent phosphorylation pattern. J Biol Chem 271:20705-20712
    • (1996) J Biol Chem , vol.271 , pp. 20705-20712
    • Caplan, S.1    Baniyash, M.2
  • 22
    • 0028851581 scopus 로고
    • Tyrosine-Phosphorylated T cell receptor zeta chain associates with the actin cytoskeleton upon activation of mature T lymphocytes
    • Rozdzial MM, Malissen B, Finkel TH (1995) Tyrosine-Phosphorylated T cell receptor zeta chain associates with the actin cytoskeleton upon activation of mature T lymphocytes. Immunity 3:623-633
    • (1995) Immunity , vol.3 , pp. 623-633
    • Rozdzial, M.M.1    Malissen, B.2    Finkel, T.H.3
  • 23
    • 0032532949 scopus 로고    scopus 로고
    • Pp 56Lck mediates TCR zeta-Chain binding to the micro fi lament cytoskeleton
    • Rozdzial MM, Pleiman CM, Cambier JC, Finkel TH (1998) pp 56Lck mediates TCR zeta-Chain binding to the micro fi lament cytoskeleton. J Immunol 161:5491-5499
    • (1998) J Immunol , vol.161 , pp. 5491-5499
    • Rozdzial, M.M.1    Pleiman, C.M.2    Cambier, J.C.3    Finkel, T.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.