Transcription factor ATF5 is required for terminal differentiation and survival of olfactory sensory neurons

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 45, 2012, Pages 18589-18594

  Wang, Shu Zong ^a   Ou, Jianhong ^a   Zhu, Lihua J ^a   Green, Michael R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Hyposmia; Neonatal death; Olfaction; Olfactory marker protein; TUJ1

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ATF5; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL MATURATION; CELL SURVIVAL; CONTROLLED STUDY; GENE EXPRESSION; HOMOZYGOTE; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL DIFFERENTIATION; NEURAL STEM CELL; NONHUMAN; OLFACTORY NERVOUS SYSTEM; PRIORITY JOURNAL; SENSORY NERVE CELL; SUCKLING; TRANSCRIPTION INITIATION;

ACTIVATING TRANSCRIPTION FACTORS; ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; CELL SURVIVAL; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLFACTORY MUCOSA; ORGAN SPECIFICITY; SENSORY RECEPTOR CELLS;

MUS;

EID: 84868527256     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210479109     Document Type: Article

References (35)

1. Persengiev SP, Green MR (2003) The role of ATF/CREB family members in cell growth, survival and apoptosis. Apoptosis 8(3):225-228. (Pubitemid 36749607)
2. Devireddy LR, Teodoro JG, Richard FA, Green MR (2001) Induction of apoptosis by a secreted lipocalin that is transcriptionally regulated by IL-3 deprivation. Science 293 (5531):829-834. (Pubitemid 32743967)
3. Persengiev SP, Devireddy LR, Green MR (2002) Inhibition of apoptosis by ATFx: A novel role for a member of the ATF/CREB family of mammalian bZIP transcription factors. Genes Dev 16(14):1806-1814. (Pubitemid 34803896)
4. Monaco SE, Angelastro JM, Szabolcs M, Greene LA (2007) The transcription factor ATF5 is widely expressed in carcinomas, and interference with its function selectively kills neoplastic, but not nontransformed, breast cell lines. Int J Cancer 120(9):1883-1890. (Pubitemid 46418363)
5. Sheng Z, et al. (2010) A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications. Nat Med 16(6):671-677.
6. Angelastro JM, et al. (2005) Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes. J Neurosci 25 (15):3889-3899. (Pubitemid 40570422)
7. Mason JL, et al. (2005) ATF5 regulates the proliferation and differentiation of oligodendrocytes. Mol Cell Neurosci 29(3):372-380. (Pubitemid 40799210)
8. Treloar HB, Miller AM, Ray A, Greer CA (2010) Development of the Olfactory System: The Neurobiology of Olfaction, ed Menini A (CRC Press, Boca Raton, FL).
9. Carter LA, MacDonald JL, Roskams AJ (2004) Olfactory horizontal basal cells demonstrate a conserved multipotent progenitor phenotype. J Neurosci 24(25):5670-5683. (Pubitemid 38857221)
10. Cheng LE, Reed RR (2007) Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis. Neuron 54(4):547-557. (Pubitemid 46756140)
11. Munger SD, Leinders-Zufall T, Zufall F (2009) Subsystem organization of the mammalian sense of smell. Annu Rev Physiol 71:115-140.
12. Belluscio L, Gold GH, Nemes A, Axel R (1998) Mice deficient in G(olf) are anosmic. Neuron 20(1):69-81. (Pubitemid 28078350)
13. Brunet LJ, Gold GH, Ngai J (1996) General anosmia caused by a targeted disruption of the mouse olfactory cyclic nucleotide-gated cation channel. Neuron 17(4):681-693. (Pubitemid 26365347)
14. Wong ST, et al. (2000) Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice. Neuron 27(3):487-497.
15. Voyron S, et al. (1999) Apoptosis in the development of the mouse olfactory epithelium. Brain Res Dev Brain Res 115(1):49-55. (Pubitemid 29288632)
16. Cowan CM, Roskams AJ (2002) Apoptosis in the mature and developing olfactory neuroepithelium. Microsc Res Tech 58(3):204-215. (Pubitemid 34832826)
17. Murrell JR, Hunter DD (1999) An olfactory sensory neuron line, odora, properly targets olfactory proteins and responds to odorants. J Neurosci 19(19):8260-8270. (Pubitemid 30226745)
18. Rawson NE, LaMantia AS (2006) Once and again: retinoic acid signaling in the developing and regenerating olfactory pathway. J Neurobiol 66(7):653-676. (Pubitemid 43941650)
19. Guillemot F, et al. (1993) Mammalian achaete-scute homolog 1 is required for the early development of olfactory and autonomic neurons. Cell 75(3):463-476. (Pubitemid 23335072)
20. Saito H, Kubota M, Roberts RW, Chi Q, Matsunami H (2004) RTP family members induce functional expression of mammalian odorant receptors. Cell 119(5):679-691. (Pubitemid 39535755)
21. Serizawa S, et al. (2006) A neuronal identity code for the odorant receptor-specific and activity-dependent axon sorting. Cell 127(5):1057-1069. (Pubitemid 44792252)
22. Dluzen D, Li G, Tacelosky D, Moreau M, Liu DX (2011) BCL-2 is a downstream target of ATF5 that mediates the prosurvival function of ATF5 in a cell type-dependent manner. J Biol Chem 286(9):7705-7713.
23. Reich A, et al. (2011) Fas/CD95 regulatory protein Faim2 is neuroprotective after transient brain ischemia. J Neurosci 31(1):225-233.
24. Duggan CD, DeMaria S, Baudhuin A, Stafford D, Ngai J (2008) Foxg1 is required for development of the vertebrate olfactory system. J Neurosci 28(20):5229-5239.
25. Murray RC, Navi D, Fesenko J, Lander AD, Calof AL (2003) Widespread defects in the primary olfactory pathway caused by loss of Mash1 function. J Neurosci 23(5):1769-1780. (Pubitemid 36314732)
26. Hirota J, Mombaerts P (2004) The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons. Proc Natl Acad Sci USA 101(23):8751-8755. (Pubitemid 38745843)
27. Gogos JA, Osborne J, Nemes A, Mendelsohn M, Axel R (2000) Genetic ablation and restoration of the olfactory topographic map. Cell 103(4):609-620.
28. Wang SZ, et al. (2006) An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation. Development 133 (17):3389-3398.
29. Irizarry RA, et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4(2):249-264.
30. Irizarry RA, et al. (2003) Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 31(4):e15.
31. Smyth GK (2004) Linear models and empirical bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3:Article3.
32. Edgar R, Domrachev M, Lash AE (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res 30(1):207-210. (Pubitemid 34679544)
33. Roth MB, Zahler AM, Stolk JA (1991) A conserved family of nuclear phosphoproteins localized to sites of polymerase II transcription. J Cell Biol 115(3):587-596. (Pubitemid 21909914)
34. Sheng Z, Wang SZ, Green MR (2009) Transcription and signalling pathways involved in BCR-ABL-mediated misregulation of 24p3 and 24p3R. EMBO J 28(7):866-876.
35. Ihaka R, Gentleman R (1996) R: A language for data analysis and graphics. J Comput Graph Statist 5(3):299-314.