The epimastigote stage-specific gene expression of CESP is tightly regulated by its 3′ UTR

Molecular and Biochemical Parasitology

Volumn 186, Issue 1, 2012, Pages 77-80

  Suganuma, Keisuke ^a   Yamasaki, Shino ^a   Asada, Masahito ^a   Kawazu, Shin Ichiro ^a   Inoue, Noboru ^a  

^a OBIHIRO UNIVERSITY OF AGRICULTURE AND VETERINARY MEDICINE   (Japan)

Author keywords

3 Untranslated region; Epimastigote form; Post transcriptional regulation; Stage specific gene expression; Trypanosoma congolense

Indexed keywords

ACTIN; CONGOLENSE EPIMASTIGOTE SPECIFIC PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; EPIMASTIGOTE; GENE CASSETTE; GENE EXPRESSION REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; TRYPANOSOMA CONGOLENSE;

3' UNTRANSLATED REGIONS; ARTIFICIAL GENE FUSION; GENE EXPRESSION REGULATION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; PROTOZOAN PROTEINS; RNA STABILITY; TRYPANOSOMA CONGOLENSE;

KINETOPLASTIDA; TRYPANOSOMA CONGOLENSE;

EID: 84868476529     PISSN: 01666851     EISSN: 18729428     Source Type: Journal    
DOI: 10.1016/j.molbiopara.2012.09.010     Document Type: Article

References (20)

1. I. Roditi, and M.J. Lehane Interactions between trypanosomes and tsetse flies Current Opinion in Microbiology 11 4 2008 345 351
2. L. Peacock, S. Cook, V. Ferris, M. Bailey, and W. Gibson The life cycle of Trypanosoma (Nannomonas) congolense in the tsetse fly Parasites & Vectors 5 2012 109
3. D.A. Evans, D.S. Ellis, and S. Stamford Ultrastructural studies of certain aspects of the development of Trypanosoma congolense in Glossina morsitans Journal of Protozoology 26 4 1979 557 563
4. J.R. Helm, C. Hertz-Fowler, M. Aslett, M. Berriman, M. Sanders, and M.A. Quail Analysis of expressed sequence tags from the four main developmental stages of Trypanosoma congolense Molecular and Biochemical Parasitology 168 1 2009 34 42
5. T. Sakurai, C. Sugimoto, and N. Inoue Identification and molecular characterization of a novel stage-specific surface protein of Trypanosoma congolense epimastigotes Molecular and Biochemical Parasitology 161 1 2008 1 11
6. J.G. De Gaudenzi, G. Noe, V.A. Campo, A.C. Frasch, and A. Cassola Gene expression regulation in trypanosomatids R. Docampo, Essays in Biochemistry 2011 Portland Press Ltd London 31 46
7. S. Kramer Developmental regulation of gene expression in the absence of transcriptional control: the case of kinetoplastids Molecular and Biochemical Parasitology 181 2 2012 61 72
8. S. Kramer, and M. Carrington Trans-acting proteins regulating mRNA maturation: stability and translation in trypanosomatids Trends in Parasitology 27 1 2011 23 30
9. A. Furger, N. Schurch, U. Kurath, and I. Roditi Elements in the 3′ untranslated region of procyclin mRNA regulate expression in insect forms of Trypanosoma brucei by modulating RNA stability and translation Molecular and Cellular Biology 17 8 1997 4372 4380
10. J. Mani, A. Guettinger, B. Schimanski, M. Heller, A. Acosta-Serrano, and P. Pescher Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery PLoS ONE 6 7 2011 e22463
11. P. Walrad, A. Paterou, A. Acosta-Serrano, and K.R. Matthews Differential trypanosome surface coat regulation by a CCCH protein that co-associates with procyclin mRNA cis-elements Plos Pathogens 5 2 2009 e1000317
12. Y. Mao, H.S. Najafabadi, and R. Salavati Genome-wide computational identification of functional RNA elements in Trypanosoma brucei BMC Genomics 10 2009 355
13. I. D'Orso, and A.C. Frasch Functionally different AU- and G-rich cis-elements confer developmentally regulated mRNA stability in Trypanosoma cruzi by interaction with specific RNA-binding proteins Journal of Biological Chemistry 276 19 2001 15783 15793
14. H. Ngo, C. Tschudi, K. Gull, and E. Ullu Double-stranded RNA induces mRNA degradation in Trypanosoma brucei Proceedings of the National Academy of Sciences of the United States of America 95 25 1998 14687 14692
15. V. Coustou, F. Guegan, N. Plazolles, and T. Baltz Complete in vitro life cycle of Trypanosoma congolense: development of genetic tools PLOS Neglected Tropical Diseases 4 3 2010 e618
16. T. Sakurai, M. Tanaka, S. Kawazu, and N. Inoue Establishment of an in vitro transgene expression system in epimastigotes of Trypanosoma congolense Parasitology International 58 1 2009 110 113
17. K. Fenn, and K.R. Matthews The cell biology of Trypanosoma brucei differentiation Current Opinion in Microbiology 10 6 2007 539 546
18. F. Bringaud, D. Baltz, and T. Baltz Functional and molecular characterization of a glycosomal PPi-dependent enzyme in trypanosomatids: pyruvate, phosphate dikinase Proceedings of the National Academy of Sciences of the United States of America 95 14 1998 7963 7968
19. S.M. Lanham, and D.G. Godfrey Isolation of salivarian trypanosomes from man and other mammals using DEAE-cellulose Experimental Parasitology 28 3 1970 521 534
20. M. Brenndorfer, and M. Boshart Selection of reference genes for mRNA quantification in Trypanosoma brucei Molecular and Biochemical Parasitology 172 1 2010 52 55