Development of a rhesus monkey lung geometry model and application to particle deposition in comparison to humans

Inhalation Toxicology

Volumn 24, Issue 13, 2012, Pages 869-899

  Asgharian, Bahman ^a   Price, Owen ^a   McClellan, Gene ^a   Corley, Rick ^b   Einstein, Daniel R ^b   Jacob, Richard E ^b   Harkema, Jack ^c   Carey, Stephan A ^c   Schelegle, Edward ^d   Hyde, Dallas ^d,e   Kimbell, Julia S ^f   Miller, Frederick J ^g  

^a APPLIED RESEARCH ASSOCIATES   (United States)

^b PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^c MICHIGAN STATE UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^g Fred J Miller and Associates LLC   (United States)

Author keywords

Breathing parameters; Deposition modeling; Humans; Lung geometry; Particles; Rhesus monkeys

Indexed keywords

ALGORITHM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; BREATHING RATE; COMPARATIVE STUDY; CONTROLLED STUDY; DOSIMETRY; EXPIRATORY FLOW RATE; FUNCTIONAL RESIDUAL CAPACITY; GEOMETRY; IN VIVO STUDY; LUNG; LUNG FUNCTION; LUNG VOLUME; MALE; MAXILLARY SINUS; MORPHOMETRICS; NONHUMAN; NOSE BREATHING; PARTICLE SIZE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RHESUS MONKEY; THREE DIMENSIONAL IMAGING; TIDAL VOLUME; TOTAL LUNG CAPACITY; TOXIC INHALATION; TRACHEOBRONCHIAL TREE;

ADMINISTRATION, INHALATION; ALGORITHMS; ANIMALS; FEMALE; HUMANS; MACACA MULATTA; MALE; MODELS, ANIMAL; MODELS, BIOLOGICAL; PARTICLE SIZE; PARTICULATE MATTER; RESPIRATORY PHYSIOLOGICAL PHENOMENA; RESPIRATORY SYSTEM;

ANIMALIA; MACACA MULATTA;

EID: 84868354640     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.3109/08958378.2012.725782     Document Type: Article

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