Synthesis, characterization and brain targeting potential of paclitaxel loaded thiamine-PPI nanoconjugates

Journal of Drug Targeting

Volumn 20, Issue 10, 2012, Pages 841-849

  Patel, Satish Kumar ^a   Gajbhiye, Virendra ^a,b   Jain, Narendra Kumar ^a  

^a DR H S GOUR UNIVERSITY   (India)

^b University of Wisconsin Madison   (United States)

Author keywords

biodistribution; brain delivery; IMR 32 human neuroblastoma; paclitaxel; PPI dendrimer; thiamine

Indexed keywords

DENDRIMER; NANOCONJUGATE; PACLITAXEL; POLYPROPYLENE; THIAMINE CONJUGATED POLY(PROPYLENE IMINE); THIAMINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN; CANCER INHIBITION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG RELEASE; DRUG SYNTHESIS; DRUG TARGETING; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLOOD-BRAIN BARRIER; BRAIN; CELL LINE, TUMOR; HUMANS; MICROSCOPY, ELECTRON, TRANSMISSION; NANOSTRUCTURES; PACLITAXEL; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THIAMINE; TISSUE DISTRIBUTION;

EID: 84868341385     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2012.719231     Document Type: Article

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