메뉴 건너뛰기




Volumn 110, Issue 2, 2012, Pages 74-83

The enhancement of stability of p53 in MTBP induced p53-MDM2 regulatory network

Author keywords

Fix point oscillation; Limit cycle; Noise parameters; Steady state solutions; Unstable and stable states

Indexed keywords


EID: 84868333883     PISSN: 03032647     EISSN: 18728324     Source Type: Journal    
DOI: 10.1016/j.biosystems.2012.09.005     Document Type: Article
Times cited : (13)

References (21)
  • 1
    • 0034644731 scopus 로고    scopus 로고
    • A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2
    • Boyd M.T., Vlatkovic N., Haines D.S. A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2. J. Biol. Chem. 2000, 275:31883-31890.
    • (2000) J. Biol. Chem. , vol.275 , pp. 31883-31890
    • Boyd, M.T.1    Vlatkovic, N.2    Haines, D.S.3
  • 2
    • 11844301301 scopus 로고    scopus 로고
    • Regulation of p53 and MDM2 activity by MTBP
    • Brady M., Vlatkovic N., Boyd M.T. Regulation of p53 and MDM2 activity by MTBP. Mol. Cell. Biol. 2005, 25:545-553.
    • (2005) Mol. Cell. Biol. , vol.25 , pp. 545-553
    • Brady, M.1    Vlatkovic, N.2    Boyd, M.T.3
  • 3
    • 0029913730 scopus 로고    scopus 로고
    • Mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein
    • Chen J., Wu X., Lin J., Levine A.J. mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol. Cell. Biol. 1996, 16:2445-2452.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2445-2452
    • Chen, J.1    Wu, X.2    Lin, J.3    Levine, A.J.4
  • 4
    • 85194544116 scopus 로고    scopus 로고
    • Elowitz,et al., Stochastic gene expression in single cell
    • Elowitz, et al. Stochastic gene expression in single cell. Science 2002, 297:1129-1131.
    • (2002) Science , vol.297 , pp. 1129-1131
  • 5
    • 0037129342 scopus 로고    scopus 로고
    • Mdm2 overexpression and p14ARF inactivation are two mutually exclusive events in primary human lung tumors
    • Eymin B., Gazzeri S., Brambilla C., Brambilla1 E. Mdm2 overexpression and p14ARF inactivation are two mutually exclusive events in primary human lung tumors. Oncogene 2002, 21:2750-2761.
    • (2002) Oncogene , vol.21 , pp. 2750-2761
    • Eymin, B.1    Gazzeri, S.2    Brambilla, C.3    Brambilla1, E.4
  • 9
    • 0029985647 scopus 로고    scopus 로고
    • Cell type-specific inhibition of p53-mediated apoptosis by mdm2
    • Haupt Y., Barak Y., Oren M. Cell type-specific inhibition of p53-mediated apoptosis by mdm2. EMBO J. 1996, 15:1596-1606.
    • (1996) EMBO J. , vol.15 , pp. 1596-1606
    • Haupt, Y.1    Barak, Y.2    Oren, M.3
  • 10
    • 0035868964 scopus 로고    scopus 로고
    • P300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
    • Ito A., Lai C.H., Zhao X., Saito S., Hamilton M.H., Appella E., Yao T.P. p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. EMBO J. 2001, 20:1331-1340.
    • (2001) EMBO J. , vol.20 , pp. 1331-1340
    • Ito, A.1    Lai, C.H.2    Zhao, X.3    Saito, S.4    Hamilton, M.H.5    Appella, E.6    Yao, T.P.7
  • 12
    • 0030965946 scopus 로고    scopus 로고
    • Regulation of p53 stability by Mdm2
    • Kubbutat M.H., Jones S.N., Vousden K.H. Regulation of p53 stability by Mdm2. Nature 1997, 387:299-303.
    • (1997) Nature , vol.387 , pp. 299-303
    • Kubbutat, M.H.1    Jones, S.N.2    Vousden, K.H.3
  • 13
    • 0032912721 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 induces Mdm2 and down regulates p53, attenuating the myocyte renin-angiotensin system and stress-mediated apoptosis
    • Leri A., Liu Y., Caudio P.P., Kajstura J., Wang X., Wang S., Kang P., Malhotra A., Anversa P. Insulin-like growth factor-1 induces Mdm2 and down regulates p53, attenuating the myocyte renin-angiotensin system and stress-mediated apoptosis. Am. J. Pathol. 1999, 154:567-580.
    • (1999) Am. J. Pathol. , vol.154 , pp. 567-580
    • Leri, A.1    Liu, Y.2    Caudio, P.P.3    Kajstura, J.4    Wang, X.5    Wang, S.6    Kang, P.7    Malhotra, A.8    Anversa, P.9
  • 15
    • 0030825813 scopus 로고    scopus 로고
    • P53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding
    • Midgley C.A., Lane D.P. p53 protein stability in tumour cells is not determined by mutation but is dependent on Mdm2 binding. Oncogene 1997, 15:1179-1189.
    • (1997) Oncogene , vol.15 , pp. 1179-1189
    • Midgley, C.A.1    Lane, D.P.2
  • 16
    • 0026740449 scopus 로고
    • Amplification of a gene encoding a p53-associated protein in human sarcomas
    • Oliner J.D., Kinzler K.W., Meltzer P.S., George D.L., Vogelstein B. Amplification of a gene encoding a p53-associated protein in human sarcomas. Nature 1992, 358:80-83.
    • (1992) Nature , vol.358 , pp. 80-83
    • Oliner, J.D.1    Kinzler, K.W.2    Meltzer, P.S.3    George, D.L.4    Vogelstein, B.5
  • 17
    • 0842285841 scopus 로고    scopus 로고
    • Summing up the noise in gene networks
    • Paulsson J. Summing up the noise in gene networks. Nature 2004, 427:415418.
    • (2004) Nature , vol.427 , pp. 415418
    • Paulsson, J.1
  • 19
    • 53149144701 scopus 로고    scopus 로고
    • Explaining oscillations and variability in p53-Mdm2 system
    • Proctor C.J., Gray D.A. Explaining oscillations and variability in p53-Mdm2 system. BMC Syst. Biol. 2008, 2:75.
    • (2008) BMC Syst. Biol. , vol.2 , pp. 75
    • Proctor, C.J.1    Gray, D.A.2
  • 21
    • 0030860911 scopus 로고    scopus 로고
    • Repression of p53-mediated transcription by MDM2: a dual mechanism
    • Thut C.J., Goodrich J.A., Tjian R. Repression of p53-mediated transcription by MDM2: a dual mechanism. Genes Dev. 1997, 11:1974-1986.
    • (1997) Genes Dev. , vol.11 , pp. 1974-1986
    • Thut, C.J.1    Goodrich, J.A.2    Tjian, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.