-
1
-
-
42649145667
-
Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol. 2008;26(10):1626-1634.
-
(2008)
J Clin Oncol
, vol.26
, Issue.10
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
2
-
-
79956298812
-
Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status
-
Van Cutsem E, Bajetta E, Valle J, et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J Clin Oncol. 2011;29(15):2011-2019.
-
(2011)
J Clin Oncol
, vol.29
, Issue.15
, pp. 2011-2019
-
-
Van Cutsem, E.1
Bajetta, E.2
Valle, J.3
-
3
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med. 2008;359(17): 1757-1765.
-
(2008)
N Engl J Med
, vol.359
, Issue.17
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
-
4
-
-
78149250536
-
Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
-
Douillard JY, Siena S, Cassidy J, et al. Randomized, phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: the PRIME study. J Clin Oncol. 2010; 28(31):4697-4705.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
-
5
-
-
78149239651
-
Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer
-
Peeters M, Price TJ, Cervantes A, et al. Randomized phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. J Clin Oncol. 2010;28(31):4706-4713.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4706-4713
-
-
Peeters, M.1
Price, T.J.2
Cervantes, A.3
-
6
-
-
0013297123
-
-
Erbitux. Princeton, NJ: Bristol-Myers Squibb Co, 7. Vectibix
-
Erbitux [package insert]. Princeton, NJ: Bristol-Myers Squibb Co; 2011. 7. Vectibix.
-
(2011)
Package Insert
-
-
-
7
-
-
0013297123
-
-
Thousand Oaks, CA: Amgen Inc
-
[package insert]. Thousand Oaks, CA: Amgen Inc; 2011.
-
(2011)
Package Insert
-
-
-
9
-
-
0003536740
-
-
US Preventive Services Task Force. 2nd ed. Baltimore, MD: Lippincott, Williams & Wilkins
-
US Preventive Services Task Force. Guide to Clinical Preventive Services. 2nd ed. Baltimore, MD: Lippincott, Williams & Wilkins; 1996.
-
(1996)
Guide to Clinical Preventive Services
-
-
-
10
-
-
38649099966
-
KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab
-
Lièvre A, Bachet J, Boige V, et al. KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. J Clin Oncol. 2008;26(3):374-379.
-
(2008)
J Clin Oncol
, vol.26
, Issue.3
, pp. 374-379
-
-
Lièvre, A.1
Bachet, J.2
Boige, V.3
-
11
-
-
40149088765
-
KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab
-
De Roock W, Piessevaux H, De Schutter J, et al. KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab. Ann Oncol. 2008;19(3):508-515.
-
(2008)
Ann Oncol
, vol.19
, Issue.3
, pp. 508-515
-
-
De Roock, W.1
Piessevaux, H.2
De Schutter, J.3
-
12
-
-
34548238762
-
Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab
-
Khambata-Ford S, Garrett C, Meropol NJ, et al. Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab. J Clin Oncol. 2007;25(22): 3230-3237.
-
(2007)
J Clin Oncol
, vol.25
, Issue.22
, pp. 3230-3237
-
-
Khambata-Ford, S.1
Garrett, C.2
Meropol, N.J.3
-
13
-
-
34247278727
-
Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by cetuximab plus chemotherapy
-
Di Fiore F, Blanchard F, Charbonnier F, et al. Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by cetuximab plus chemotherapy. Br J Cancer. 2007;96(8):1166-1169.
-
(2007)
Br J Cancer
, vol.96
, Issue.8
, pp. 1166-1169
-
-
Di, F.F.1
Blanchard, F.2
Charbonnier, F.3
-
14
-
-
34047248571
-
Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
-
Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res. 2007;67(6):2643-2648.
-
(2007)
Cancer Res
, vol.67
, Issue.6
, pp. 2643-2648
-
-
Benvenuti, S.1
Sartore-Bianchi, A.2
Di, N.F.3
-
15
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Köhne CH, Hitre E, et al. Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer. N Engl J Med. 2009;360(14): 1408-1417.
-
(2009)
N Engl J Med
, vol.360
, Issue.14
, pp. 1408-1417
-
-
Van Cutsem, E.1
Köhne, C.H.2
Hitre, E.3
-
16
-
-
49149109102
-
Randomized phase III study of capecitabine, oxaliplatin, and bevacizumab with or without cetuximab in advanced colorectal cancer (ACC), the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG) [abstract]
-
Punt C, Tol J, Rodenburg CJ, et al. Randomized phase III study of capecitabine, oxaliplatin, and bevacizumab with or without cetuximab in advanced colorectal cancer (ACC), the CAIRO2 study of the Dutch Colorectal Cancer Group (DCCG) [abstract]. J Clin Oncol. 2008;26(15 suppl): LBA4011.
-
(2008)
J Clin Oncol
, vol.26
, Issue.15 SUPPL..
-
-
Punt, C.1
Tol, J.2
Rodenburg, C.J.3
-
17
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
-
Bokemeyer C, Bondarenko I, Makhson A, et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J Clin Oncol. 2009;27(5):663-671.
-
(2009)
J Clin Oncol
, vol.27
, Issue.5
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
-
18
-
-
65349189958
-
American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti- epidermal growth factor receptor monoclonal antibody therapy
-
Allegra C, Jessup M, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to anti- epidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol. 2009;27(12):2091-2096.
-
(2009)
J Clin Oncol
, vol.27
, Issue.12
, pp. 2091-2096
-
-
Allegra, C.1
Jessup, M.2
Somerfield, M.R.3
-
19
-
-
81355161586
-
Uptake of KRAS mutation testing in patients with metastatic colorectal cancer in Europe, Latin America and Asia
-
Ciardiello F, Tejpar S, Normanno N, et al. 2011. Uptake of KRAS mutation testing in patients with metastatic colorectal cancer in Europe, Latin America and Asia. Target Oncol. 2011;6(3):133-145.
-
(2011)
Target Oncol, 2011
, vol.6
, Issue.3
, pp. 133-145
-
-
Ciardiello, F.1
Tejpar, S.2
Normanno, N.3
-
21
-
-
54249098184
-
KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: Proposal for an European quality assurance program
-
van Krieken J, Jung A, Kirchner T, et al. KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program. Virchows Arch. 2008;453(5):417-431.
-
(2008)
Virchows Arch
, vol.453
, Issue.5
, pp. 417-431
-
-
Van Krieken, J.1
Jung, A.2
Kirchner, T.3
-
22
-
-
51649084560
-
Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer
-
Artale S, Sartore-Bianchi A, Veronese SM, et al. Mutations of KRAS and BRAF in primary and matched metastatic sites of colorectal cancer. J Clin Oncol. 2008;26(25):4217-4219.
-
(2008)
J Clin Oncol
, vol.26
, Issue.25
, pp. 4217-4219
-
-
Artale, S.1
Sartore-Bianchi, A.2
Veronese, S.M.3
-
23
-
-
70449377167
-
Targeted KRAS mutation assessment on patient tumor histologic material in real time diagnostics
-
Kotoula V, Charalambous E, Biesmans B, et al. Targeted KRAS mutation assessment on patient tumor histologic material in real time diagnostics. PLoS One. 2009;4(11):e7746.
-
(2009)
PLoS One
, vol.4
, Issue.11
-
-
Kotoula, V.1
Charalambous, E.2
Biesmans, B.3
-
24
-
-
77950846704
-
A comparability study of 5 commercial KRAS tests
-
Oliner K, Juan T, Suggs S, et al. A comparability study of 5 commercial KRAS tests. Diagn Pathol. 2010;5:23.
-
(2010)
Diagn Pathol
, vol.5
, pp. 23
-
-
Oliner, K.1
Juan, T.2
Suggs, S.3
-
26
-
-
79955017287
-
KRAS mutation testing in the treatment of metastatic colorectal cancer with anti-EGFR therapies
-
Soulieres D, Greer W, Magliocco AM, et al. 2010. KRAS mutation testing in the treatment of metastatic colorectal cancer with anti-EGFR therapies. Curr Oncol. 2010;17(suppl 1):S31-S40.
-
(2010)
Curr Oncol 2010
, vol.17
, Issue.SUPPL.. 1
-
-
Soulieres, D.1
Greer, W.2
Magliocco, A.M.3
-
27
-
-
70350462904
-
A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting
-
Whitehall V, Tran K, Umapathy A, et al. A multicenter blinded study to evaluate KRAS mutation testing methodologies in the clinical setting. J Mol Diagn. 2009;11(6):543-552.
-
(2009)
J Mol Diagn
, vol.11
, Issue.6
, pp. 543-552
-
-
Whitehall, V.1
Tran, K.2
Umapathy, A.3
-
28
-
-
79960435101
-
Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer
-
Molinari F, Felicioni L, Buscarino M, et al. Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer. Clin Cancer Res. 2011;17(14):4901- 4914.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.14
, pp. 4901-4914
-
-
Molinari, F.1
Felicioni, L.2
Buscarino, M.3
-
29
-
-
84870926109
-
Comprehensive next-generation sequencing for clinically actionable mutations from formalin-fixed cancer tissues [abstract]
-
Ross J, Lipson R, Yelensky R, et al. Comprehensive next-generation sequencing for clinically actionable mutations from formalin-fixed cancer tissues [abstract]. J Clin Oncol. 2011;29(15 suppl):10564.
-
(2011)
J Clin Oncol
, vol.29
, Issue.15 SUPPL..
, pp. 10564
-
-
Ross, J.1
Lipson, R.2
Yelensky, R.3
-
30
-
-
0034082024
-
Detection of mutated KRAS2 sequences as tumor markers in plasma/serum of patients with gastrointestinal cancer
-
Sorenson GD. Detection of mutated KRAS2 sequences as tumor markers in plasma/serum of patients with gastrointestinal cancer. Clin Cancer Res. 2000; 6(6):2129-2137.
-
(2000)
Clin Cancer Res
, vol.6
, Issue.6
, pp. 2129-2137
-
-
Sorenson, G.D.1
-
31
-
-
33846228264
-
Correlation of K-RAS codon 12 mutations in human feces and ages of patients with colorectal cancer (CRC)
-
Chien CC, Chen SH, Liu CC, et al. Correlation of K-RAS codon 12 mutations in human feces and ages of patients with colorectal cancer (CRC). Transl Res. 2007;149(2):96-102.
-
(2007)
Transl Res
, vol.149
, Issue.2
, pp. 96-102
-
-
Chien, C.C.1
Chen, S.H.2
Liu, C.C.3
-
32
-
-
34147222554
-
Mutant-enriched PCR and allelespecific hybridization reaction to detect K-ras mutations in stool DNA: High prevalence in a large sample of older adults
-
Haug U, Hillebrand T, Bendzko P, et al. Mutant-enriched PCR and allelespecific hybridization reaction to detect K-ras mutations in stool DNA: high prevalence in a large sample of older adults. Clin Chem. 2007;53(4):787-790.
-
(2007)
Clin Chem
, vol.53
, Issue.4
, pp. 787-790
-
-
Haug, U.1
Hillebrand, T.2
Bendzko, P.3
-
33
-
-
0035815919
-
Detecting colorectal cancer in stool with the use of multiple genetic targets
-
Dong SM, Traverso G, Johnson C, et al. Detecting colorectal cancer in stool with the use of multiple genetic targets. J Natl Cancer Inst. 2001;93(11): 858-865.
-
(2001)
J Natl Cancer Inst
, vol.93
, Issue.11
, pp. 858-865
-
-
Dong, S.M.1
Traverso, G.2
Johnson, C.3
-
34
-
-
82455221643
-
Cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer treated with third-line cetuximab and irinotecan [abstract]
-
Pallisgaard N, Spindler K, Vogelius IS, and Jakobsen AKM. Cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer treated with third-line cetuximab and irinotecan [abstract]. J Clin Oncol. 2011;29(15 suppl):3599.
-
(2011)
J Clin Oncol
, vol.29
, Issue.15 SUPPL..
, pp. 3599
-
-
Pallisgaard, N.1
Spindler, K.2
Vogelius, I.S.3
Jakobsen, A.K.M.4
-
35
-
-
77958557955
-
Molecular biomarker analyses using circulating tumor cells
-
Punnoose E, Atwal S, Spoerke JM, et al. Molecular biomarker analyses using circulating tumor cells. PLoS One. 2010;5(9):e12517.
-
(2010)
PLoS One
, vol.5
, Issue.9
-
-
Punnoose, E.1
Atwal, S.2
Spoerke, J.M.3
-
36
-
-
79952698311
-
External quality assessment for KRAS testing is needed: Setup of a European program and report of the first joined regional quality assessment rounds
-
Bellon E, Ligtenberg M, Tejpar S, et al. External quality assessment for KRAS testing is needed: setup of a European program and report of the first joined regional quality assessment rounds. Oncologist. 2011;16(4):467-478.
-
(2011)
Oncologist
, vol.16
, Issue.4
, pp. 467-478
-
-
Bellon, E.1
Ligtenberg, M.2
Tejpar, S.3
-
37
-
-
57349105253
-
Tissue handling and specimen preparation in surgical pathology: Issues concerning the recovery of nucleic acids from formalin-fixed, paraffin-embedded tissue
-
Hewitt SM, Lewis FA, Cao Y. Tissue handling and specimen preparation in surgical pathology: issues concerning the recovery of nucleic acids from formalin-fixed, paraffin-embedded tissue. Arch Pathol Lab Med. 2008;132(12): 1929-1935.
-
(2008)
Arch Pathol Lab Med
, vol.132
, Issue.12
, pp. 1929-1935
-
-
Hewitt, S.M.1
Lewis, F.A.2
Cao, Y.3
-
38
-
-
79959753442
-
-
US Department of Health and Human Services. Clinical Laboratory Improvement Amendments (CLIA). Accessed November 22, 2011
-
US Department of Health and Human Services. Centers for Medicare and Medicaid Services. Clinical Laboratory Improvement Amendments (CLIA). http://www.cms.gov/clia. Accessed November 22, 2011.
-
Centers for Medicare and Medicaid Services
-
-
-
39
-
-
84859561489
-
-
Accessed August 31, 2011
-
College of American Pathologists. Accreditation and laboratory improvement. http://www.cap.org/apps/cap.portal?-nfpb5true&- pageLabel5accreditation. Accessed August 31, 2011.
-
Accreditation and Laboratory Improvement
-
-
-
40
-
-
34250175491
-
Clinical laboratory reports in molecular pathology
-
Gulley M, Braziel R, Halling KC, et al. Clinical laboratory reports in molecular pathology. Arch Pathol Lab Med. 2007;131(6):852-863.
-
(2007)
Arch Pathol Lab Med
, vol.131
, Issue.6
, pp. 852-863
-
-
Gulley, M.1
Braziel, R.2
Halling, K.C.3
-
41
-
-
78049341541
-
Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab
-
De Roock W, Jonker DJ, Di Nicolantonio F, et al. Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. JAMA. 2010; 304(16): 1812-1820.
-
(2010)
JAMA
, vol.304
, Issue.16
, pp. 1812-1820
-
-
De Roock, W.1
Jonker, D.J.2
Di Nicolantonio, F.3
-
42
-
-
79960892233
-
Influence of KRAS G13D mutations on outcome in patients with metastatic colorectal cancer (mCRC) treated with first-line chemotherapy with or without cetuximab [abstract]
-
Tejpar S, Bokemeyer C, Celik I, et al. Influence of KRAS G13D mutations on outcome in patients with metastatic colorectal cancer (mCRC) treated with first-line chemotherapy with or without cetuximab [abstract]. J Clin Oncol. 2011; 29(15 suppl):3511.
-
(2011)
J Clin Oncol
, vol.29
, Issue.15 SUPPL..1
, pp. 3511
-
-
Tejpar, S.1
Bokemeyer, C.2
Celik, I.3
-
43
-
-
68749119351
-
KRAS codon 61, 146, and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
-
Loupakis F, Ruzzo A, Cremolini C, et al. KRAS codon 61, 146, and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. Br J Cancer. 2009;101(4):715-721.
-
(2009)
Br J Cancer
, vol.101
, Issue.4
, pp. 715-721
-
-
Loupakis, F.1
Ruzzo, A.2
Cremolini, C.3
-
45
-
-
77949435827
-
Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer
-
Bardelli A, Siena A. Molecular mechanisms of resistance to cetuximab and panitumumab in colorectal cancer. J Clin Oncol. 2010;28(7):1254-1261.
-
(2010)
J Clin Oncol
, vol.28
, Issue.7
, pp. 1254-1261
-
-
Bardelli, A.1
Siena, A.2
-
46
-
-
73349094741
-
Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer
-
Laurent-Puig P, Cayre, A, Manceau G, et al. Analysis of PTEN, BRAF, and EGFR status in determining benefit from cetuximab therapy in wild-type KRAS metastatic colon cancer. J Clin Oncol. 2009;27(35):5924-5930.
-
(2009)
J Clin Oncol
, vol.27
, Issue.35
, pp. 5924-5930
-
-
Laurent-Puig, P.1
Cayre, A.2
Manceau, G.3
-
47
-
-
70350028742
-
Multideterminants analysis of molecular alterations for predicting clinical benefit to EGFR targeted monoclonal antibodies in colorectal cancer
-
Sartore-Bianchi A, Di Nicolantonio F, Nichelatti M, et al. Multideterminants analysis of molecular alterations for predicting clinical benefit to EGFR targeted monoclonal antibodies in colorectal cancer. PLoS One. 2009; 4(10):e7287.
-
(2009)
PLoS One
, vol.4
, Issue.10
-
-
Sartore-Bianchi, A.1
Di, N.F.2
Nichelatti, M.3
-
48
-
-
77955277111
-
Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
-
De Roock W, Claes B, Bernasconi D, et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol. 2010;11(8):753-762.
-
(2010)
Lancet Oncol
, vol.11
, Issue.8
, pp. 753-762
-
-
De Roock, W.1
Claes, B.2
Bernasconi, D.3
-
49
-
-
57449095367
-
Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
-
Di Nicolantonio F, Martini M, Molinari F, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol. 2008;26(35):5705-5712.
-
(2008)
J Clin Oncol
, vol.26
, Issue.35
, pp. 5705-5712
-
-
Di, N.F.1
Martini, M.2
Molinari, F.3
-
50
-
-
77949886293
-
Analysis of potential predictive markers of cetuximab benefit in BMS099, a phase III study of cetuximab and first-line taxane/carboplatin in advanced non-small-cell lung cancer
-
Khambata-Ford S, Harbison C, Hart L, et al. Analysis of potential predictive markers of cetuximab benefit in BMS099, a phase III study of cetuximab and first-line taxane/carboplatin in advanced non-small-cell lung cancer. J Clin Oncol. 2010;28(6):918-927.
-
(2010)
J Clin Oncol
, vol.28
, Issue.6
, pp. 918-927
-
-
Khambata-Ford, S.1
Harbison, C.2
Hart, L.3
-
51
-
-
79960894047
-
Molecular biomarkers in non-small-cell lung cancer: A retrospective analysis of data from the phase 3 FLEX study
-
O'Byrne KJ, Gatzemeier U, Bondarenko I, et al. Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study. Lancet Oncol. 2011;12(8):795-805.
-
(2011)
Lancet Oncol
, vol.12
, Issue.8
, pp. 795-805
-
-
O'Byrne, K.J.1
Gatzemeier, U.2
Bondarenko, I.3
-
52
-
-
52749099497
-
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: A systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
-
Linardou H, Dahabreh IJ, Kanaloupiti D, Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer. Lancet Oncol. 2008;9(10):962-972.
-
(2008)
Lancet Oncol
, vol.9
, Issue.10
, pp. 962-972
-
-
Linardou, H.1
Dahabreh, I.J.2
Kanaloupiti, D.3
-
53
-
-
52049090365
-
Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
-
Zhu C, da Cunha Santos G, Ding K, et al. Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol. 2008;26(26):4268-4275.
-
(2008)
J Clin Oncol
, vol.26
, Issue.26
, pp. 4268-4275
-
-
Zhu, C.1
Da, C.S.G.2
Ding, K.3
-
54
-
-
80755181069
-
Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer
-
Brugger W, Triller N, Blasinska-Morawiec M, et al. Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer. J Clin Oncol. 2011;29(31):4113-4120.
-
(2011)
J Clin Oncol
, vol.29
, Issue.31
, pp. 4113-4120
-
-
Brugger, W.1
Triller, N.2
Blasinska-Morawiec, M.3
-
55
-
-
77649222572
-
Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: Data from the randomized phase III INTEREST trial
-
Douillard JY, Shepherd FA, Hirsh V, et al. Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: data from the randomized phase III INTEREST trial. J Clin Oncol. 2010;28(5): 744-752.
-
(2010)
J Clin Oncol
, vol.28
, Issue.5
, pp. 744-752
-
-
Douillard, J.Y.1
Shepherd, F.A.2
Hirsh, V.3
-
56
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman P, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med. 2011; 364(26):2507-2516.
-
(2011)
N Engl J Med
, vol.364
, Issue.26
, pp. 2507-2516
-
-
Chapman, P.1
Hauschild, A.2
Robert, C.3
-
57
-
-
78649723255
-
PLX4032 in metastatic colorectal cancer patients with mutant BRAF tumors [abstract]
-
Kopetz S, Desai J, Chan E, et al. PLX4032 in metastatic colorectal cancer patients with mutant BRAF tumors [abstract]. J Clin Oncol. 2010;28(15 suppl): 3534.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 SUPPL..
, pp. 3534
-
-
Kopetz, S.1
Desai, J.2
Chan, E.3
-
58
-
-
79956310674
-
Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: The OPUS study
-
Bokemeyer C, Bondarenko I, Hartmann JT, et al. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol. 2011;22(7):1535- 1546.
-
(2011)
Ann Oncol
, vol.22
, Issue.7
, pp. 1535-1546
-
-
Bokemeyer, C.1
Bondarenko, I.2
Hartmann, J.T.3
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