Rational formulation design

International Journal of Cosmetic Science

Volumn 34, Issue 6, 2012, Pages 496-501

  Lane, Majella E ^a   Hadgraft, J ^a   Oliveira, G ^a   Vieira, R ^a   Mohammed, D ^a   Hirata, K ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

formulating for efficacy; formulation; permeation; solubility; solvent

Indexed keywords

1 METHYL 2 PYRROLIDINONE; ACID; CARBENOXOLONE; CLONIDINE; COSMETIC; DIETHYLENE GLYCOL MONOETHYL ETHER; DIMETHYL ISOSORBIDE; DRUG VEHICLE; FENTANYL; GLYCEROL; IBUPROFEN; ISOSORBIDE DERIVATIVE; LAURIC ACID DERIVATIVE; MIGLYOL; MINERAL OIL; MYRISTIC ACID ISOPROPYL ESTER; NICOTINAMIDE; NICOTINIC ACID METHYL ESTER; OXYBUTYNIN; PROPYLENE GLYCOL; PROPYLENE GLYCOL LAURATE; PROPYLENE GLYCOL MONOLAURATE; SALICYLIC ACID OCTYL ESTER; SCOPOLAMINE; SOLVENT; STEROID; UNCLASSIFIED DRUG; WATER;

DIFFUSION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DISPOSITION; DRUG EFFICACY; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG TRANSPORT; HUMAN; LIPOPHILICITY; MONITORING; PARTITION COEFFICIENT; PERMEABILITY BARRIER; REVIEW; SIMULATION; SKIN PENETRATION; SOLVENT EFFECT; STRATUM CORNEUM; THERMODYNAMICS;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; COSMETICS; HUMANS; PHARMACEUTICAL VEHICLES; SKIN ABSORPTION; SOLUBILITY; THERMODYNAMICS;

EID: 84868302012     PISSN: 01425463     EISSN: 14682494     Source Type: Journal    
DOI: 10.1111/j.1468-2494.2012.00747.x     Document Type: Review

References (14)

1. Scot, R. The Discoverie of Witchcraft, Book III, chap 1; Book X, chap 8. Elliot Stock, London (1886).
2. Higuchi, T. Physical chemical analysis of percutaneous absorption process from creams and ointments. J. Soc. Cosmet. Chem. 11, 8597 (1960).
3. Katz, M. and Poulsen, B.J. Corticosteroid, vehicle and skin interaction in percutaneous absorption. J. Soc. Cosmet. Chem. 23, 565-590 (1972).
4. Hadgraft, J.; Hadgraft, J.W. and Sarkany, I. Proceedings: the effect of thermodynamic activity on the percutaneous absorption of methyl nicotinate from water glycerol mixtures. J. Pharm. Pharmacol. 25(Suppl), 122-123 (1973).
5. Coldman, M.F.; Poulsen, B.J. and Higuchi, T. Enhancement of percutaneous absorption by the use of volatile: non-volatile systems as vehicles. J. Pharm. Sci. 58, 10981102 (1969)
6. Davis, A.F. and Hadgraft, J. Effect of supersaturation on membrane transport. 1. Hydrocortisone acetate. Int. J. Pharm. 76, 1 8 (1991).
7. Marks, R.; Dykes, P.J.; Gordon, J.; Hanlan, G. and Davis, A.F. Percutaneous penetration from a low dose supersaturated hydrocortisone acetate formulation. Br. J. Dermatol. 127, 433 (1992).
8. Feldmann, R.J. Maibach, H.I. Regional variation in percutaneous penetration of 14C cortisol in man. J. Invest. Dermatol. 48, 181-183 (1967).
9. Wiechers, J.W.; Kelly, C.L.; Blease, T.G. and Dederen, J.C. Formulating for efficacy. Int. J. Cosmet. Sci. 26, 173182 (2004).
10. Santos, P.; Watkinson, A.C.; Hadgraft, J. and Lane, M.E. Oxybutynin permeation in skin: the influence of drug and solvent activity. Int. J. Pharm. 384, 6772 (2010).
11. Abbott, S. An integrated approach to optimizing skin delivery of cosmetic and pharmaceutical actives. Int. J. Cosmet. Sci. 34, 217222 (2012).
12. Hirata, K.. Topical formulation strategies for a model acidic and model basic drug. PhD. Thesis, University of London (2011).
13. Mohammed, D.; Matts, P.J.; Hadgraft, J. and Lane, M.E. Development and evaluation of topical niacinamide formulations. In press (2012).
14. Melot, M.; Pudney, P.D.; Williamson, A.M.; Caspers, P.J.; Van Der Pol, A. and Puppels, G.J. Studying the effectiveness of penetration enhancers to deliver retinol through the stratum cornum by in vivo confocal Raman spectroscopy. J. Control. Release 138, 3239 (2009).