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Volumn 78, Issue 3, 2012, Pages 239-244

Bevacizumab and erlotinib (BE) first-line therapy in advanced non-squamous non-small-cell lung cancer (NSCLC) (stage IIIB/IV) followed by platinum-based chemotherapy (CT) at disease progression: A multicenter phase II trial (SAKK 19/05)

(18)  Zappa, Francesco a   Droege, Cornelia b   Betticher, Daniel c   von Moos, Roger d   Bubendorf, Lukas b   Ochsenbein, Adrian e   Gautschi, Oliver e   Oppliger Leibundgut, Elisabeth e   Froesch, Patrizia a   Stahel, Rolf f   Hess, Thomas g   Rauch, Daniel d   Schmid, Petra h   Mayer, Michael i   Crowe, Susanne i   Brauchli, Peter i   Ribi, Karin j   Pless, Miklos g  


Author keywords

Bevacizumab; Erlotinib; First line regimen; Metastatic; Non squamous NSCLC; Translational research

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CISPLATIN; ERLOTINIB; GEMCITABINE;

EID: 84868301289     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2012.08.017     Document Type: Article
Times cited : (33)

References (30)
  • 1
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer
    • Schiller J.H., et al. Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med 2002, 346(2):92-98.
    • (2002) N Engl J Med , vol.346 , Issue.2 , pp. 92-98
    • Schiller, J.H.1
  • 2
    • 3042673101 scopus 로고    scopus 로고
    • Cytotoxic chemotherapy in advanced non-small cell lung cancer: a review of standard treatment paradigms
    • Socinski M.A. Cytotoxic chemotherapy in advanced non-small cell lung cancer: a review of standard treatment paradigms. Clin Cancer Res 2004, 10(12 (Pt 2)):4210s-4214s.
    • (2004) Clin Cancer Res , vol.10 , Issue.12 PART 2
    • Socinski, M.A.1
  • 3
    • 77954601010 scopus 로고    scopus 로고
    • Targeted therapies for non-small cell lung cancer: an evolving landscape
    • Pal S.K., Figlin R.A., Reckamp K. Targeted therapies for non-small cell lung cancer: an evolving landscape. Mol Cancer Ther 2010, 9(7):1931-1944.
    • (2010) Mol Cancer Ther , vol.9 , Issue.7 , pp. 1931-1944
    • Pal, S.K.1    Figlin, R.A.2    Reckamp, K.3
  • 4
    • 45849133426 scopus 로고    scopus 로고
    • Bevacizumab for the treatment of advanced non-small-cell lung cancer
    • Manegold C. Bevacizumab for the treatment of advanced non-small-cell lung cancer. Expert Rev Anticancer Ther 2008, 8(5):689-699.
    • (2008) Expert Rev Anticancer Ther , vol.8 , Issue.5 , pp. 689-699
    • Manegold, C.1
  • 5
    • 62449124416 scopus 로고    scopus 로고
    • Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil
    • Reck M., et al. Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol 2009, 27(8):1227-1234.
    • (2009) J Clin Oncol , vol.27 , Issue.8 , pp. 1227-1234
    • Reck, M.1
  • 6
    • 33845490014 scopus 로고    scopus 로고
    • Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
    • Sandler A., et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006, 355(24):2542-2550.
    • (2006) N Engl J Med , vol.355 , Issue.24 , pp. 2542-2550
    • Sandler, A.1
  • 7
    • 77951473661 scopus 로고    scopus 로고
    • Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL)
    • Reck M., et al. Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL). Ann Oncol 2010, 21(9):1804-1809.
    • (2010) Ann Oncol , vol.21 , Issue.9 , pp. 1804-1809
    • Reck, M.1
  • 8
    • 77955268612 scopus 로고    scopus 로고
    • Safety and efficacy of first-line bevacizumab-based therapy in advanced non-squamous non-small-cell lung cancer (SAiL, MO19390): a phase 4 study
    • Crino L., et al. Safety and efficacy of first-line bevacizumab-based therapy in advanced non-squamous non-small-cell lung cancer (SAiL, MO19390): a phase 4 study. Lancet Oncol 2010, 11(8):733-740.
    • (2010) Lancet Oncol , vol.11 , Issue.8 , pp. 733-740
    • Crino, L.1
  • 9
    • 22044445517 scopus 로고    scopus 로고
    • Erlotinib in previously treated non-small-cell lung cancer
    • Shepherd F.A., et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med 2005, 353(2):123-132.
    • (2005) N Engl J Med , vol.353 , Issue.2 , pp. 123-132
    • Shepherd, F.A.1
  • 10
    • 41549125361 scopus 로고    scopus 로고
    • Multicenter phase II trial of gefitinib first-line therapy followed by chemotherapy in advanced non-small-cell lung cancer (NSCLC): SAKK protocol 19/03
    • D'Addario G., et al. Multicenter phase II trial of gefitinib first-line therapy followed by chemotherapy in advanced non-small-cell lung cancer (NSCLC): SAKK protocol 19/03. Ann Oncol 2008, 19(4):739-745.
    • (2008) Ann Oncol , vol.19 , Issue.4 , pp. 739-745
    • D'Addario, G.1
  • 11
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok T.S., et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009, 361(10):947-957.
    • (2009) N Engl J Med , vol.361 , Issue.10 , pp. 947-957
    • Mok, T.S.1
  • 12
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial
    • Rosell R., et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012, 13(3):239-246.
    • (2012) Lancet Oncol , vol.13 , Issue.3 , pp. 239-246
    • Rosell, R.1
  • 13
    • 28044433677 scopus 로고    scopus 로고
    • Epidermal growth factor receptor and angiogenesis: opportunities for combined anticancer strategies
    • van Cruijsen H., Giaccone G., Hoekman K. Epidermal growth factor receptor and angiogenesis: opportunities for combined anticancer strategies. Int J Cancer 2005, 117(6):883-888.
    • (2005) Int J Cancer , vol.117 , Issue.6 , pp. 883-888
    • van Cruijsen, H.1    Giaccone, G.2    Hoekman, K.3
  • 14
    • 20244381389 scopus 로고    scopus 로고
    • Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer
    • Herbst R.S., et al. Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lung cancer. J Clin Oncol 2005, 23(11):2544-2555.
    • (2005) J Clin Oncol , vol.23 , Issue.11 , pp. 2544-2555
    • Herbst, R.S.1
  • 15
    • 0034594628 scopus 로고    scopus 로고
    • New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
    • Therasse P., et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000, 92(3):205-216.
    • (2000) J Natl Cancer Inst , vol.92 , Issue.3 , pp. 205-216
    • Therasse, P.1
  • 16
    • 0028267598 scopus 로고
    • Measurement of quality of life in patients with lung cancer in multicenter trials of new therapies. Psychometric assessment of the Lung Cancer Symptom Scale
    • Hollen P.J., et al. Measurement of quality of life in patients with lung cancer in multicenter trials of new therapies. Psychometric assessment of the Lung Cancer Symptom Scale. Cancer 1994, 73(8):2087-2098.
    • (1994) Cancer , vol.73 , Issue.8 , pp. 2087-2098
    • Hollen, P.J.1
  • 17
    • 58149206195 scopus 로고
    • Quality of life assessment in individuals with lung cancer: testing the Lung Cancer Symptom Scale (LCSS)
    • Hollen P.J., et al. Quality of life assessment in individuals with lung cancer: testing the Lung Cancer Symptom Scale (LCSS). Eur J Cancer 1993, 29A(Suppl. 1):S51-S58.
    • (1993) Eur J Cancer , vol.29 A , Issue.SUPPL. 1
    • Hollen, P.J.1
  • 18
    • 0036137886 scopus 로고    scopus 로고
    • Patients' estimation of overall treatment burden: why not ask the obvious?
    • Bernhard J., et al. Patients' estimation of overall treatment burden: why not ask the obvious?. J Clin Oncol 2002, 20(1):65-72.
    • (2002) J Clin Oncol , vol.20 , Issue.1 , pp. 65-72
    • Bernhard, J.1
  • 19
    • 17744369809 scopus 로고    scopus 로고
    • Clinical vs Statistical Significance: Using the LCSS Quality of Life Instrument and Karnofsky Performance Status (KPS) to Approach the Problem in Patients with Non-Small Cell Lung Cancer (NSCLC)
    • (abstr 2510)
    • Hollen P.J., Gralla R.J. Clinical vs Statistical Significance: Using the LCSS Quality of Life Instrument and Karnofsky Performance Status (KPS) to Approach the Problem in Patients with Non-Small Cell Lung Cancer (NSCLC). J Clin Oncol 2000, 19(Suppl.). (abstr 2510).
    • (2000) J Clin Oncol , vol.19 , Issue.SUPPL.
    • Hollen, P.J.1    Gralla, R.J.2
  • 20
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
    • Scagliotti G.V., et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 2008, 26(21):3543-3551.
    • (2008) J Clin Oncol , vol.26 , Issue.21 , pp. 3543-3551
    • Scagliotti, G.V.1
  • 21
    • 77953541527 scopus 로고    scopus 로고
    • Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study
    • Cappuzzo F., et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol 2010, 11(6):521-529.
    • (2010) Lancet Oncol , vol.11 , Issue.6 , pp. 521-529
    • Cappuzzo, F.1
  • 22
    • 70350225538 scopus 로고    scopus 로고
    • Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study
    • Ciuleanu T., et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study. Lancet 2009, 374(9699):1432-1440.
    • (2009) Lancet , vol.374 , Issue.9699 , pp. 1432-1440
    • Ciuleanu, T.1
  • 23
    • 59149092945 scopus 로고    scopus 로고
    • Phase III study of immediate compared with delayed docetaxel after front-line therapy with gemcitabine plus carboplatin in advanced non-small-cell lung cancer
    • Fidias P.M., et al. Phase III study of immediate compared with delayed docetaxel after front-line therapy with gemcitabine plus carboplatin in advanced non-small-cell lung cancer. J Clin Oncol 2009, 27(4):591-598.
    • (2009) J Clin Oncol , vol.27 , Issue.4 , pp. 591-598
    • Fidias, P.M.1
  • 24
    • 84857507055 scopus 로고    scopus 로고
    • Maintenance therapy with pemetrexed plus best supportive care versus placebo plus best supportive care after induction therapy with pemetrexed plus cisplatin for advanced non-squamous non-small-cell lung cancer (PARAMOUNT): a double-blind, phase 3, randomised controlled trial
    • Paz-Ares L., et al. Maintenance therapy with pemetrexed plus best supportive care versus placebo plus best supportive care after induction therapy with pemetrexed plus cisplatin for advanced non-squamous non-small-cell lung cancer (PARAMOUNT): a double-blind, phase 3, randomised controlled trial. Lancet Oncol 2012, 13(3):247-255.
    • (2012) Lancet Oncol , vol.13 , Issue.3 , pp. 247-255
    • Paz-Ares, L.1
  • 25
    • 84865154870 scopus 로고    scopus 로고
    • First-line erlotinib followed by second-line cisplatin-gemcitabine chemotherapy in advanced non-small-cell lung cancer: the TORCH randomized trial
    • Gridelli C., et al. First-line erlotinib followed by second-line cisplatin-gemcitabine chemotherapy in advanced non-small-cell lung cancer: the TORCH randomized trial. J Clin Oncol 2012.
    • (2012) J Clin Oncol
    • Gridelli, C.1
  • 26
    • 56249109644 scopus 로고    scopus 로고
    • Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial
    • Kim E.S., et al. Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial. Lancet 2008, 372(9652):1809-1818.
    • (2008) Lancet , vol.372 , Issue.9652 , pp. 1809-1818
    • Kim, E.S.1
  • 27
    • 56749173617 scopus 로고    scopus 로고
    • Bevacizumab and erlotinib: a promising new approach to the treatment of advanced NSCLC
    • Herbst R.S., Sandler A. Bevacizumab and erlotinib: a promising new approach to the treatment of advanced NSCLC. Oncologist 2008, 13(11):1166-1176.
    • (2008) Oncologist , vol.13 , Issue.11 , pp. 1166-1176
    • Herbst, R.S.1    Sandler, A.2
  • 28
    • 79952031192 scopus 로고    scopus 로고
    • First-line erlotinib and bevacizumab in patients with locally advanced and/or metastatic non-small-cell lung cancer: a phase II study including molecular imaging
    • Dingemans A.M., et al. First-line erlotinib and bevacizumab in patients with locally advanced and/or metastatic non-small-cell lung cancer: a phase II study including molecular imaging. Ann Oncol 2011, 22(3):559-566.
    • (2011) Ann Oncol , vol.22 , Issue.3 , pp. 559-566
    • Dingemans, A.M.1
  • 29
    • 84861973944 scopus 로고    scopus 로고
    • Innovations: randomized phase II trial of erlotinib (E)/bevacizumab (B) compared with cisplatin (P)/gemcitabine (G) plus B in first-line treatment of advanced nonsquamous (NS) non-small cell lung cancer (NSCLC)
    • abstr 7504
    • Thomas M., et al. Innovations: randomized phase II trial of erlotinib (E)/bevacizumab (B) compared with cisplatin (P)/gemcitabine (G) plus B in first-line treatment of advanced nonsquamous (NS) non-small cell lung cancer (NSCLC). J Clin Oncol 2011, 29(Suppl.). abstr 7504.
    • (2011) J Clin Oncol , vol.29 , Issue.SUPPL.
    • Thomas, M.1
  • 30
    • 79957823572 scopus 로고    scopus 로고
    • Efficacy of bevacizumab plus erlotinib versus erlotinib alone in advanced non-small-cell lung cancer after failure of standard first-line chemotherapy (BeTa): a double-blind, placebo-controlled, phase 3 trial
    • Herbst R.S., et al. Efficacy of bevacizumab plus erlotinib versus erlotinib alone in advanced non-small-cell lung cancer after failure of standard first-line chemotherapy (BeTa): a double-blind, placebo-controlled, phase 3 trial. Lancet 2011, 377(9780):1846-1854.
    • (2011) Lancet , vol.377 , Issue.9780 , pp. 1846-1854
    • Herbst, R.S.1


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