Neutron diffraction studies of the interaction between amphotericin B and lipid-sterol model membranes

Scientific Reports

Volumn 2, Issue , 2012, Pages

  Foglia, Fabrizia ^a   Lawrence, M Jayne ^a   Demee, Bruno ^b   Fragneto, Giovanna ^b   Barlow, David ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b Institut de Laue Langevin   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; CHOLESTEROL; ERGOSTEROL; LIPID; MEMBRANE LIPID; STEROL;

ARTICLE; CHEMISTRY; NEUTRON DIFFRACTION;

AMPHOTERICIN B; CHOLESTEROL; ERGOSTEROL; LIPIDS; MEMBRANE LIPIDS; NEUTRON DIFFRACTION; STEROLS;

EID: 84868271598     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep00778     Document Type: Article

References (38)

1. Enoch, D.A., Ludlam, H. A. & Brown, N. M.Invasive fungal infections: areview of epidemiology and management options. J Med. Microbiol. 55, 809-818 (2006). (Pubitemid 43974685)
2. Warnock, D. W. Trends in the epidemiology of invasive fungal infections. J. Med. Mycol. 48, 809-818 (2007).
3. Lass-Flo, C. The changing face of epidemiology of invasive fungal disease in Europe. Mycoses 52, 197-205 (2009).
4. White, T. C., Marr, K. A. & Bowden, R. A. Clinical, cellular, and molecular factors that contribute to antifungal drug resistance. Clinical Microbiol. Rev. 11, 382-402 (1998). (Pubitemid 28197359)
5. Vandeputte, P., Ferrari, S. & Coste, A. T. Antifungal resistance and new strategies to control fungal infections. Int. J. Microbiol. 2012, Article ID 713687 (2012).
6. Pfaller, M. A. Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatment. Am. J. Med. 125 (Suppl 1), S3-S13 (2012).
7. Shin, J. H. et al. Detection of amphotericin B resistance in Candida haemulonii and closely related species by use of the Etest, Vitek-2 yeast susceptibility system, and CLSI and EUCAST broth microdilution methods. J Clinical Microbiol. 50, 1852-5 (2012).
8. Sutton, D. A. et al. In vitro amphotericin B resistance in clinical isolates of Aspergillus terreus, with a head-to-head comparison to voriconazole. J. Clinical Microbiol. 37, 2343-2345 (1999). (Pubitemid 29277804)
9. Hadrich, I. et al. Amphotericin B resistance is associated with fatal Aspergillus flavus infection. Medical Mycology 2012, EPUB 1-6 (2012).
10. Gallis, H. A., Drew, R. H. & Pickard, W. W. Amphotericin B: 30 years of clinical experience. Rev. Infect. Diseases 12, 308-329.
11. Deray, G. Amphotericin B nephrotoxicity. J. Antimicr. Chemother. 49 (Suppl. S1), 37-41 (2002). (Pubitemid 34162655)
12. Finkelstein, A. & Holz, R. Aqueous pores created in thin lipid membranes by the polyene antibiotics nystatin and amphotericin B. Membranes 2, 377-348 (1973).
13. Hsuchen, C.-C. & Feingold, D. S. Selective membrane toxicity of the polyene antibiotics: studies on lecithin model membranes (liposomes). Antimicrob. Agents Chemother. 4, 309-315 (1973).
14. Marty, A. & Finkelstein, A. Pores formed by nystatin. differences in its one-side and two-side action. J. Gen. Physiol. 65, 515-526 (1975).
15. Cohen, B. E. A sequential mechanism for the formation of aqueous channels by amphotericin-B in liposomes-the effect of sterols and phospholipid- composition, Biochim. Biophys. Acta-Biomembranes 1108, 49-58 (1992).
16. Cotero, B. V., Rebolledo-Antunez, S. & Ortega-Blake, I. On the role of sterol in the formation ofthe amphotericinBchannel. Biochim. Biophys. Acta-Biomembranes 1375, 43-51 (1998). (Pubitemid 28514428)
17. Venegas, B., González-Damián, J., Celis, H. & Ortega-Blake, I. Amphotericin B channels in the bacterial membrane: role of sterol and temperature. Biophys. J. 85, 2323-2332 (2003). (Pubitemid 37210782)
18. Wang, M. M., Sugar, I. P. & Chong, P. L. G. Role of the sterol superlattice in the partitioning of the antifungal drug nystatin into lipid membranes. Biochem. 37, 11797-11805 (1998). (Pubitemid 28400051)
19. Gray, K. C. et al. Amphotericin primarily kills yeast by simply binding ergosterol. Proc. Natl. Acad. Sci. (U.S.A) 109, 2234-2239 (2012).
20. Foglia, F. F. et al. Small angle neutron scattering studies of the effects of amphotericin B on phospholipid and phospholipid-sterol membrane structure. Biochim. Biophys. Acta-Biomembranes 1808, 1574-1580 (2010).
21. 31P-NMR spectroscopy. Biochim. Biophys. Acta-Biomembranes 1238, 163-176 (1995).
22. Katarzyna, H. W. & Patrycja, D. L. Interaction between nystatin and natural membrane lipids in Langmuir monolayers-The role of a phospholipid in the mechanism of polyenes' mode of action. Biophys. Chem. 123, 154-161 (2006).
23. Minones, J., Conde, O., Dynarowicz-Latka, P. & Casas, M. Penetration of amphotericinBinto DOPC monolayers containing sterols of cellular membranes. Colloids & Surfaces A 270, 129-137 (2005). (Pubitemid 41726410)
24. Herec, M., Islamov, A., Kuklin, A., Gagoś, M. & Gruszecki, W. I. Effect of antibiotic amphotericin B on structural and dynamic properties of lipid membranes formed with egg yolk phosphatidylcholine. Chem. Phys. Lipids 147, 78-86 (2007). (Pubitemid 46818168)
25. Gagoś, M., Gabrielska, J., Dalla Serra, M. & Gruszecki, W. I. Binding of antibiotic amphotericin B to lipid membranes: monomolecular layer technique and linear dichroism-FTIR studies. Mol. Membrane Biol. 22, 433-442 (2005). (Pubitemid 41747105)
26. van Hoogevest, P. & de Kruijff, B. Effect of amphotericin on cholesterol-containing liposomes of egg phosphatidylcholine and didocosenoyl phosphatidylcholine. Biochim. Biophys. Acat-Biomembranes 511, 397-407 (1978).
27. Matsumori, N., Sawada, Y. & Murata, M. Mycosamine Orientation of amphotericin B controlling interaction with ergosterol: sterol-dependent activity of conformation-restricted derivatives with an amino-carbonyl bridge. J. Am. Chem. Soc. 127, 10667-10675 (2005). (Pubitemid 41061440)
28. Schneck, E. et al. Mechanical properties of interacting lipopolysaccharide membranes from bacteria mutants studied by specular and off-specular neutron scattering. Phys. Rev. E 80, 041929/1 (2009).
29. Tristram-Nagle, S. et al. Biophys. J. 64, 1097 (1993).
30. Tristram-Nagle, S., Liu, Y., Legleiter, J. & Nagle, J. F. Structure of gel pahse DMPC determined by X-ray diffraction. Biophys. J. 83, 3324-3335 (2002). (Pubitemid 36041950)
31. Franks, N. P. & Lieb, W. R. Structures of lipid bilayers and the effects of general anaesthetics: X-ray and neutron diffraction study. J. Mol. Biol. 133, 469-500 (1979). (Pubitemid 10157903)
32. Han, X. & Hirstova, K. Viewing the bilayer hydrophobic core using neutron diffraction. J. Membrane Biol. 227, 123-131 (2009).
33. www.ncnr.nist.gov/instruments/bt1/neutron.html
34. Gogol, E. P., Engelman, D. M. & Zaccai, G. Neutron diffraction analysis of cytochrom b5 reconstituted in deuterated lipid bilayers. Biophys. J. 43, 285-292 (1983).
35. Zaccai, G., Blasie, J. K. & Schoenborn, B. P. Neutron diffraction studies on location of water in lecithin bilayer model membranes. Proc. Natl. Acad. Sci. (USA) 72, 376-380 (1975).
36. Jacobs, R. E. & White, S. H. The nature of the hydrophobic binding of small peptides at the bilayer interface-implications for the insertion of transbilayer helices. Biochem. 28, 3421-3437 (1989). (Pubitemid 19121937)
37. Worcester, D. L. & Frank, N. P. Structural analysis of hydrated egg lecithin and cholesterol bilayers 2. Neutron diffraction. J. Mol. Biol. 100, 359-378 (1976).
38. Léonard, A. et al. Location of cholesterol in DMPC membranes: a comparative study by neutron diffraction and molecular mechanics simulation. Langmuir 17, 2019-2030 (2001). (Pubitemid 35330089)