-
1
-
-
47749099634
-
Myostatin as a therapeutic target for musculoskeletal disease
-
L. Bradley, P.J. Yaworsky, and F.S. Walsh Myostatin as a therapeutic target for musculoskeletal disease Cell Mol. Life Sci. 65 2008 2119 2124
-
(2008)
Cell Mol. Life Sci.
, vol.65
, pp. 2119-2124
-
-
Bradley, L.1
Yaworsky, P.J.2
Walsh, F.S.3
-
2
-
-
72149090398
-
Receptors for myelin inhibitors: Structures and therapeutic opportunities
-
Z. Cao, Y. Gao, K. Deng, G. Williams, P. Doherty, and F.S. Walsh Receptors for myelin inhibitors: structures and therapeutic opportunities Mol. Cell Neurosci. 43 2010 1 14
-
(2010)
Mol. Cell Neurosci.
, vol.43
, pp. 1-14
-
-
Cao, Z.1
Gao, Y.2
Deng, K.3
Williams, G.4
Doherty, P.5
Walsh, F.S.6
-
4
-
-
77953811009
-
Dissection of the IgNAR v domain: Molecular scanning and orthologue database mining define novel IgNAR hallmarks and affinity maturation mechanisms
-
B.J. Fennell, A. Darmanin-Sheehan, S.E. Hufton, V. Calabro, L. Wu, M.R. Müller, W. Cao, D. Gill, O. Cunningham, and W.J. Finlay Dissection of the IgNAR V domain: molecular scanning and orthologue database mining define novel IgNAR hallmarks and affinity maturation mechanisms J. Mol. Biol. 400 2010 155 170
-
(2010)
J. Mol. Biol.
, vol.400
, pp. 155-170
-
-
Fennell, B.J.1
Darmanin-Sheehan, A.2
Hufton, S.E.3
Calabro, V.4
Wu, L.5
Müller, M.R.6
Cao, W.7
Gill, D.8
Cunningham, O.9
Finlay, W.J.10
-
6
-
-
0030029277
-
Amyotrophic Lateral Sclerosis: Current and future therapeutic strategies
-
B.W. Festoff Amyotrophic Lateral Sclerosis: current and future therapeutic strategies Drugs 51 1996 28 44
-
(1996)
Drugs
, vol.51
, pp. 28-44
-
-
Festoff, B.W.1
-
7
-
-
77955474140
-
Protein pharmaceuticals: Discovery and preclinical development
-
D.S. Gill Protein pharmaceuticals: discovery and preclinical development Adv. Exp. Med. Biol. 655 2009 28 36
-
(2009)
Adv. Exp. Med. Biol.
, vol.655
, pp. 28-36
-
-
Gill, D.S.1
-
8
-
-
84856223048
-
New drugs for ALS: How do we get there?
-
J.D. Glass New drugs for ALS: how do we get there? Exp. Neurol. 233 2012 112 117
-
(2012)
Exp. Neurol.
, vol.233
, pp. 112-117
-
-
Glass, J.D.1
-
9
-
-
0028962371
-
A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks
-
A.S. Greenberg, D. Avila, M. Hughes, A. Hughes, E.C. McKinney, and M.F. Flajnik A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks Nature 374 1995 168 173
-
(1995)
Nature
, vol.374
, pp. 168-173
-
-
Greenberg, A.S.1
Avila, D.2
Hughes, M.3
Hughes, A.4
McKinney, E.C.5
Flajnik, M.F.6
-
10
-
-
33747223762
-
Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis
-
E.L. Holzbaur, D.S. Howland, N. Weber, K. Wallace, Y. She, S. Kwak, L.A. Tchistiakova, E. Murphy, J. Hinson, R. Karim, X.Y. Tan, P. Kelley, K.C. McGill, G. Williams, C. Hobbs, P. Doherty, M.M. Zaleska, M.N. Pangalos, and F.S. Walsh Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis Neurobiol. Dis. 23 2006 697 707
-
(2006)
Neurobiol. Dis.
, vol.23
, pp. 697-707
-
-
Holzbaur, E.L.1
Howland, D.S.2
Weber, N.3
Wallace, K.4
She, Y.5
Kwak, S.6
Tchistiakova, L.A.7
Murphy, E.8
Hinson, J.9
Karim, R.10
Tan, X.Y.11
Kelley, P.12
McGill, K.C.13
Williams, G.14
Hobbs, C.15
Doherty, P.16
Zaleska, M.M.17
Pangalos, M.N.18
Walsh, F.S.19
-
11
-
-
79551661945
-
Transforming growth factor-β signaling in motor neuron diseases
-
M. Katsuno, H. Adachi, H. Banno, K. Suzuki, F. Tanaka, and G. Sobue Transforming growth factor-β signaling in motor neuron diseases Curr. Mol. Med. 11 2011 48 56
-
(2011)
Curr. Mol. Med.
, vol.11
, pp. 48-56
-
-
Katsuno, M.1
Adachi, H.2
Banno, H.3
Suzuki, K.4
Tanaka, F.5
Sobue, G.6
-
12
-
-
60549106515
-
Single muscle fiber contractile properties in adults with muscular dystrophy treated with MYO-029
-
L.S. Krivickas, R. Walsh, and A.A. Amato Single muscle fiber contractile properties in adults with muscular dystrophy treated with MYO-029 Muscle Nerve 39 2009 3 9
-
(2009)
Muscle Nerve
, vol.39
, pp. 3-9
-
-
Krivickas, L.S.1
Walsh, R.2
Amato, A.A.3
-
13
-
-
77950835644
-
Motor neuron disease: Focusing the mind on ALS: Updated practice parameters
-
P.N. Leigh, and L.C. Wijesekera Motor neuron disease: focusing the mind on ALS: updated practice parameters Nat. Rev. Neurol. 6 2010 191 192
-
(2010)
Nat. Rev. Neurol.
, vol.6
, pp. 191-192
-
-
Leigh, P.N.1
Wijesekera, L.C.2
-
14
-
-
24344452642
-
Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice
-
S. McCroskery, M. Thomas, L. Platt, A. Hennebry, T. Nishimura, L. McLeay, M. Sharma, and R. Kambadur Improved muscle healing through enhanced regeneration and reduced fibrosis in myostatin-null mice J. Cell Sci. 118 2005 3531 3541
-
(2005)
J. Cell Sci.
, vol.118
, pp. 3531-3541
-
-
McCroskery, S.1
Thomas, M.2
Platt, L.3
Hennebry, A.4
Nishimura, T.5
McLeay, L.6
Sharma, M.7
Kambadur, R.8
-
15
-
-
0031010050
-
Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
-
A.C. McPherron, A.M. Lawler, and S.J. Lee Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member Nature 387 1997 83 90
-
(1997)
Nature
, vol.387
, pp. 83-90
-
-
McPherron, A.C.1
Lawler, A.M.2
Lee, S.J.3
-
16
-
-
33845876647
-
Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis
-
T.M. Miller, S.H. Kim, K. Yamanaka, M. Hester, P. Umapathi, H. Arnson, L. Rizo, J.R. Mendell, F.H. Gage, D.W. Cleveland, and B.K. Kaspar Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis Proc. Natl. Acad. Sci. USA 103 2006 19546 19551
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19546-19551
-
-
Miller, T.M.1
Kim, S.H.2
Yamanaka, K.3
Hester, M.4
Umapathi, P.5
Arnson, H.6
Rizo, L.7
Mendell, J.R.8
Gage, F.H.9
Cleveland, D.W.10
Kaspar, B.K.11
-
17
-
-
84856905668
-
Current and prospective disease-modifying therapies for amyotrophic lateral sclerosis
-
J.A. Morren, and N. Galves-Jiminez Current and prospective disease-modifying therapies for amyotrophic lateral sclerosis Expert Opin. Investig. Drugs 21 2012 297 320
-
(2012)
Expert Opin. Investig. Drugs
, vol.21
, pp. 297-320
-
-
Morren, J.A.1
Galves-Jiminez, N.2
-
18
-
-
67349251521
-
A soluble activin type IIB receptor improves function in a mouse model of amyotrophic lateral sclerosis
-
B.M. Morrison, J.L. Lachey, L.C. Warsing, B.L. Ting, A.E. Pullen, K.W. Underwood, R. Kumar, D. Sako, A. Grinberg, V. Wong, E. Colantuoni, J.S. Seehra, and K.R. Wagner A soluble activin type IIB receptor improves function in a mouse model of amyotrophic lateral sclerosis Exp. Neurol. 217 2009 258 268
-
(2009)
Exp. Neurol.
, vol.217
, pp. 258-268
-
-
Morrison, B.M.1
Lachey, J.L.2
Warsing, L.C.3
Ting, B.L.4
Pullen, A.E.5
Underwood, K.W.6
Kumar, R.7
Sako, D.8
Grinberg, A.9
Wong, V.10
Colantuoni, E.11
Seehra, J.S.12
Wagner, K.R.13
-
19
-
-
0022542291
-
Purification of a membrane protein distributed in a topographic gradient in chicken retina
-
J.R. Moskal, D. Trisler, M.D. Schneider, and M. Nirenberg Purification of a membrane protein distributed in a topographic gradient in chicken retina Proc. Natl. Acad. Sci. USA 83 1986 4730 4733
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4730-4733
-
-
Moskal, J.R.1
Trisler, D.2
Schneider, M.D.3
Nirenberg, M.4
-
20
-
-
54849406976
-
Display scaffolds: Protein engineering for novel therapeutics
-
S.B. Nuttall, and R.B. Walsh Display scaffolds: protein engineering for novel therapeutics Curr. Opin. Pharmacol. 8 2008 609 615
-
(2008)
Curr. Opin. Pharmacol.
, vol.8
, pp. 609-615
-
-
Nuttall, S.B.1
Walsh, R.B.2
-
21
-
-
0030837018
-
The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse
-
S.P. Oh, and E. Li The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse Genes Dev. 14 1997 1812 1826
-
(1997)
Genes Dev.
, vol.14
, pp. 1812-1826
-
-
Oh, S.P.1
Li, E.2
-
22
-
-
0034719477
-
Inhibitor of neurite outgrowth in humans
-
R. Prinjha, S.E. Moore, M. Vinson, S. Blake, R. Morrow, G. Christie, D. Michalovich, D.L. Simmons, and F.S. Walsh Inhibitor of neurite outgrowth in humans Nature 403 2000 383 384
-
(2000)
Nature
, vol.403
, pp. 383-384
-
-
Prinjha, R.1
Moore, S.E.2
Vinson, M.3
Blake, S.4
Morrow, R.5
Christie, G.6
Michalovich, D.7
Simmons, D.L.8
Walsh, F.S.9
-
23
-
-
84898336877
-
Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases
-
A.J. Russell, J.J. Hartman, A.C. Hinken, A.R. Muci, R. Kawas, L. Driscoll, G. Godinez, K.H. Lee, D. Marquez, W.F. Browne, M.M. Chen, D. Clarke, S.E. Collibee, M. Garard, R. Hansen, Z. Jia, P. Lu, H. Rodriguez, K.G. Saikali, J. Schaletzky, V. Vijayakumar, D.L. Albertus, D.R. Claflin, D.J. Morgans, B.P. Morgan, and F. Malik Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseases Nature Med. 378 2011 667 675
-
(2011)
Nature Med.
, vol.378
, pp. 667-675
-
-
Russell, A.J.1
Hartman, J.J.2
Hinken, A.C.3
Muci, A.R.4
Kawas, R.5
Driscoll, L.6
Godinez, G.7
Lee, K.H.8
Marquez, D.9
Browne, W.F.10
Chen, M.M.11
Clarke, D.12
Collibee, S.E.13
Garard, M.14
Hansen, R.15
Jia, Z.16
Lu, P.17
Rodriguez, H.18
Saikali, K.G.19
Schaletzky, J.20
Vijayakumar, V.21
Albertus, D.L.22
Claflin, D.R.23
Morgans, D.J.24
Morgan, B.P.25
Malik, F.26
more..
-
24
-
-
0028985272
-
Molecular cloning of TOPAP: A topographically graded protein in the developing chick visual system
-
J.M. Savitt, D. Trisler, and D.C. Hilt Molecular cloning of TOPAP: a topographically graded protein in the developing chick visual system Neuron 14 1995 253 261
-
(1995)
Neuron
, vol.14
, pp. 253-261
-
-
Savitt, J.M.1
Trisler, D.2
Hilt, D.C.3
-
25
-
-
35448995279
-
Neurotrophic factors: A tool for therapeutic strategies in neurological, neuropsychiatric and neuroimmunological diseases?
-
O. Schulte-Herbrüggen, A. Braun, S. Rochlitzer, M.C. Jockers-Scherübl, and R. Hellweg Neurotrophic factors: a tool for therapeutic strategies in neurological, neuropsychiatric and neuroimmunological diseases? Curr. Med. Chem. 14 2007 2318 2329
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 2318-2329
-
-
Schulte-Herbrüggen, O.1
Braun, A.2
Rochlitzer, S.3
Jockers-Scherübl, M.C.4
Hellweg, R.5
-
26
-
-
78651127719
-
Chemoaffinity in the orderly growth of nerve fibre patterns and connections
-
R.W. Sperry Chemoaffinity in the orderly growth of nerve fibre patterns and connections Proc. Natl. Acad. Sci. USA 50 1963 703 710
-
(1963)
Proc. Natl. Acad. Sci. USA
, vol.50
, pp. 703-710
-
-
Sperry, R.W.1
-
27
-
-
27644475866
-
Structure of a shark IgNAR antibody variable domain and modeling of an early-developmental isotype
-
V.A. Streltsov, J.A. Carmichael, and S.D. Nuttall Structure of a shark IgNAR antibody variable domain and modeling of an early-developmental isotype Protein Sci. 14 2005 2901 2909
-
(2005)
Protein Sci.
, vol.14
, pp. 2901-2909
-
-
Streltsov, V.A.1
Carmichael, J.A.2
Nuttall, S.D.3
-
28
-
-
0023644081
-
Corresponding spatial gradients of TOP molecules in the developing retina and optic tectum
-
D. Trisler, and F. Collins Corresponding spatial gradients of TOP molecules in the developing retina and optic tectum Science 237 1987 1208 1209
-
(1987)
Science
, vol.237
, pp. 1208-1209
-
-
Trisler, D.1
Collins, F.2
-
29
-
-
44849140764
-
A phase I/II trial of MYO-029 in adult subjects with muscular dystrophy
-
K.R. Wagner, J.L. Fleckenstein, A.A. Amato, R.J. Barohn, K. Bushby, D.M. Escolar, K.M. Flanigan, A. Pestronk, R. Tawil, G.I. Wolfe, M. Eagle, J.M. Florence, W.M. King, S. Pandya, V. Straub, P. Juneau, K. Meyers, C. Csimma, T. Araujo, R. Allen, S.A. Parsons, J.M. Wozney, E.R. Lavallie, and J.R. Mendell A phase I/II trial of MYO-029 in adult subjects with muscular dystrophy Ann. Neurol. 63 2008 5615 5671
-
(2008)
Ann. Neurol.
, vol.63
, pp. 5615-5671
-
-
Wagner, K.R.1
Fleckenstein, J.L.2
Amato, A.A.3
Barohn, R.J.4
Bushby, K.5
Escolar, D.M.6
Flanigan, K.M.7
Pestronk, A.8
Tawil, R.9
Wolfe, G.I.10
Eagle, M.11
Florence, J.M.12
King, W.M.13
Pandya, S.14
Straub, V.15
Juneau, P.16
Meyers, K.17
Csimma, C.18
Araujo, T.19
Allen, R.20
Parsons, S.A.21
Wozney, J.M.22
Lavallie, E.R.23
Mendell, J.R.24
more..
-
30
-
-
0031439129
-
Neural cell adhesion molecules of the immunoglobulin superfamily: Role in axon growth and guidance
-
F.S. Walsh, and P. Doherty Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidance Annu. Rev. Cell Dev. Biol. 13 1997 425 456
-
(1997)
Annu. Rev. Cell Dev. Biol.
, vol.13
, pp. 425-456
-
-
Walsh, F.S.1
Doherty, P.2
-
31
-
-
0037462964
-
Inhibition of myostatin in adult mice increases skeletal muscle mass and strength
-
L.A. Whittemore, K. Song, X. Li, J. Aghajanian, M. Davies, S. Girgenrath, J.J. Hill, M. Jalenak, P. Kelley, A. Knight, R. Maylor, D. O'Hara, A. Pearson, A. Quazi, S. Ryerson, X.Y. Tan, K.N. Tomkinson, G.M. Veldman, A. Widom, J.F. Wright, S. Wudyka, L. Zhao, and N.M. Wolfman Inhibition of myostatin in adult mice increases skeletal muscle mass and strength Biochem. Biophys. Res. Commun. 300 2003 965 971
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.300
, pp. 965-971
-
-
Whittemore, L.A.1
Song, K.2
Li, X.3
Aghajanian, J.4
Davies, M.5
Girgenrath, S.6
Hill, J.J.7
Jalenak, M.8
Kelley, P.9
Knight, A.10
Maylor, R.11
O'Hara, D.12
Pearson, A.13
Quazi, A.14
Ryerson, S.15
Tan, X.Y.16
Tomkinson, K.N.17
Veldman, G.M.18
Widom, A.19
Wright, J.F.20
Wudyka, S.21
Zhao, L.22
Wolfman, N.M.23
more..
-
33
-
-
0017584586
-
Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: Differentiation antigens of rat lymphocytes
-
A.F. Williams, G. Galfrè, and C. Milstein Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes Cell 12 1977 63 73
-
(1977)
Cell
, vol.12
, pp. 63-73
-
-
Williams, A.F.1
Galfrè, G.2
Milstein, C.3
-
34
-
-
79954608945
-
Emerging targets and treatments in amyotrophic lateral sclerosis
-
L. Zinman, and M. Culdowicz Emerging targets and treatments in amyotrophic lateral sclerosis Lancet Neurol. 10 2011 481 490.
-
(2011)
Lancet Neurol.
, vol.10
, pp. 481-490
-
-
Zinman, L.1
Culdowicz, M.2
|