Pediatric epilepsy surgery: Long-term 5-year seizure remission and medication use

Neurosurgery

Volumn 71, Issue 5, 2012, Pages 985-993

  Hauptman, Jason S ^a   Pedram, Kayvon ^a   Sison, Christia Angela ^a   Sankar, Raman ^b,c   Salamon, Noriko ^d   Vinters, Harry V ^b,e   Mathern, Gary W ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Department of Neurology ^*  (United States)

^c Division of Pediatric Neurology   (United States)

^d Division of Neuroradiology   (United States)

^e MATTEL CHILDREN S HOSPITAL   (United States)

Author keywords

Children; Epilepsy; Focal; Hemispherectomy; Infantile spasms; Surgery

Indexed keywords

ANTICONVULSIVE AGENT;

ADULT; ALEXANDER DISEASE; ARTICLE; BENIGN CHILDHOOD EPILEPSY; BRAIN CORTEX; CHILD; DEATH; DRUG THERAPY; FEMALE; HEMISPHERE; HEMISPHERECTOMY; HIPPOCAMPAL SCLEROSIS; HUMAN; MAJOR CLINICAL STUDY; MALE; NEOPLASM; PRIORITY JOURNAL; RECURRENT DISEASE; REMISSION; TREATMENT OUTCOME;

ADOLESCENT; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; EPILEPSY; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; INFANT; LOGISTIC MODELS; MAGNETIC RESONANCE IMAGING; MALE; PEDIATRICS; POSITRON-EMISSION TOMOGRAPHY; RECURRENCE; TIME FACTORS; TREATMENT OUTCOME;

EID: 84868193277     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/NEU.0b013e31826cdd5a     Document Type: Article

References (47)

1. Wiebe S, Blume WT, Girvin JP, Eliasziw M. A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med. 2001;345(5):311-318.
2. Kwan P, Schachter SC, Brodie MJ. Drug-resistant epilepsy. N Engl J Med. 2011; 365(10):919-926.
3. Kwan P, Arzimanoglou A, Berg AT, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia. 2010;51(6):1069-1077.
4. Cross JH, Jayakar P, Nordli D, et al. Proposed criteria for referral and evaluation of children for epilepsy surgery: recommendations of the Subcommission for Pediatric Epilepsy Surgery. Epilepsia. 2006;47(6):952-959.
5. Harvey AS, Cross JH, Shinnar S, Mathern BW. Defining the spectrum of international practice in pediatric epilepsy surgery patients. Epilepsia. 2008;49(1): 146-155.
6. Jonas R, Nguyen S, Hu B, et al. Cerebral hemispherectomy: hospital course, seizure, developmental, language, and motor outcomes. Neurology. 2004;62(10): 1712-1721.
7. Jonas R, Asarnow RF, LoPresti C, et al. Surgery for symptomatic infant-onset epileptic encephalopathy with and without infantile spasms. Neurology. 2005;64 (4):746-750.
8. Cepeda C, André VM, Flores-Hernández J, et al. Pediatric cortical dysplasia: correlations between neuroimaging, electrophysiology and location of cytomegalic neurons and balloon cells and glutamate/GABA synaptic circuits. Dev Neurosci. 2005;27(1):59-76.
9. Vinters HV. Histopathology of brain tissue from patients with infantile spasms. Int Rev Neurobiol. 2002;49:63-76.
10. Salamon N, Kung J, Shaw SJ, et al. FDG-PET/MRI coregistration improves detection of cortical dysplasia in patients with epilepsy. Neurology. 2008;71(20): 1594-1601.
11. Wu JY, Sankar R, Lerner JT, et al. Removing interictal fast ripples on electrocorticography linked with seizure freedom in children. Neurology. 2010; 75(19):1686-1694.
12. Wu JY, Sutherling WW, Koh S, et al. Magnetic source imaging localizes epileptogenic zone in children with tuberous sclerosis complex. Neurology. 2006; 66(8):1270-1272.
13. Chandra PS, Salamon N, Huang J, et al. FDG-PET/MRI coregistration and diffusion-tensor imaging distinguish epileptogenic tubers and cortex in patients with tuberous sclerosis complex: a preliminary report. Epilepsia. 2006;47(9): 1543-1549.
14. Prakash N, Uhlemann F, Sheth SA, Bookheimer S, Martin N, Toga AW. Current trends in intraoperative optical imaging for functional brain mapping and delineation of lesions of language cortex. Neuroimage. 2009;47(suppl 2):T116-T126.
15. Hemb M, Velasco TR, Parnes MS, et al. Improved outcomes in pediatric epilepsy surgery: the UCLA experience, 1986-2008. Neurology. 2010;74(22):1768-1775.
16. Mathern GW, Giza CC, Yudovin S, et al. Postoperative seizure control and antiepileptic drug use in pediatric epilepsy surgery patients: the UCLA experience, 1986-1997. Epilepsia. 1999;40(12):1740-1749
17. Guidelines for epidemiologic studies on epilepsy. Commission on epidemiology and prognosis, international League against epilepsy. Epilepsia. 1993;34(4):592-596.
18. Sillanpää M, Shinnar S. Long-term mortality in childhood-onset epilepsy. N Engl J Med. 2010;363(26):2522-2529.
19. Berg AT, Mathern GW, Bronen RA, et al. Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy. Brain. 2009;132():2785-2797.
20. Nolan MA, Redoblado MA, Lah S, et al. Intelligence in childhood epilepsy syndromes. Epilepsy Res. 2003;53(1-2):139-150.
21. Spencer S, Huh L. Outcomes of epilepsy surgery in adults and children. Lancet Neurol. 2008;7(6):525-537.
22. Skirrow C, Cross JH, Cormack F, et al. Long-term intellectual outcome after temporal lobe surgery in childhood. Neurology. 2011;76(15):1330-1337.
23. Racoosin JA, Feeney J, Burkhart G, Boehm G. Mortality in antiepileptic drug development programs. Neurology. 2001;56(4):514-519.
24. Benifla M, Rutka JT, Otsubo H, et al. Long-term seizure and social outcomes following temporal lobe surgery for intractable epilepsy during childhood. Epilepsy Res. 2008;82(2-3):133-138.
25. Lopez-Gonzalez MA, Gonzalez-Martinez JA, Jehi L, Kotagal P, Warbel A, Bingaman W. Epilepsy surgery of the temporal lobe in pediatric population: a retrospective analysis. Neurosurgery. 2012;70(3):684-692.
26. Lerner JT, Salamon N, Hauptman JS, et al. Assessment and surgical outcomes for mild type I and severe type II cortical dysplasia: a critical review and the UCLA experience. Epilepsia. 2009;50(6):1310-1335.
27. Loddenkemper T, Holland KD, Stanford LD, et al. Developmental outcome after epilepsy surgery in infancy. Pediatrics. 2007;119(5):930-935.
28. Elsharkawy AE, Behne F, Oppel F, et al. Long-term outcome of extratemporal epilepsy surgery among 154 adult patients. J Neurosurg. 2008;108(4):676-686.
29. Elsharkawy AE, Alabbasi AH, Pannek H, et al. Long-term outcome after temporal lobe epilepsy surgery in 434 consecutive adult patients. J Neurosurg. 2009;110(6): 1135-1146.
30. Phi JH, Kim SK, Cho BK, et al. Long-term surgical outcomes of temporal lobe epilepsy associated with low-grade brain tumors. Cancer. 2009;115(24):5771-5779.
31. Tanriverdi T, Olivier A, Poulin N, Andermann F, Dubeau F. Long-term seizure outcome after mesial temporal lobe epilepsy surgery: cortical amygdalohippo-campectomy versus selective amygdalohippocampectomy. J Neurosurg. 2008;108 (3):517-524.
32. Tezer FI, Akalan N, Oguz KK, et al. Predictive factors for postoperative outcome in temporal lobe epilepsy according to two different classifications. Seizure. 2008; 17(6):549-560.
33. Cohen-Gadol AA, Wilhelmi BG, Collignon F, et al. Long-term outcome of epilepsy surgery among 399 patients with nonlesional seizure foci including mesial temporal lobe sclerosis. J Neurosurg. 2006;104(4):513-524.
34. Dupont S, Tanguy ML, Clemenceau S, et al. Long-term prognosis and psychosocial outcomes after surgery for MTLE. Epilepsia. 2006;47(12):2115-2124.
35. Téllez-Zenteno JF, Dhar R, Wiebe S. Long-term seizure outcomes following epilepsy surgery: a systematic review and meta-analysis. Brain. 2005;128(pt 5):1188-1198.
36. Wieser HG, Ortega M, Friedman A, Yonekawa Y. Long-term seizure outcomes following amygdalohippocampectomy. J Neurosurg. 2003;98(4):751-763.
37. McIntosh AM, Kalnins RM, Mitchell LA, Fabinyi GC, Briellmann RS, Berkovic SF. Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence. Brain. 2004;127(pt 9):2018-2030.
38. Yoon HH, Kwon HL, Mattson RH, Spencer DD, Spencer SS. Long-term seizure outcome in patients initially seizure-free after resective epilepsy surgery. Neurology. 2003;61(4):445-450.
39. Hamiwka L, Jayakar P, Resnick T, et al. Surgery for epilepsy due to cortical malformations: ten-year follow-up. Epilepsia. 2005;46(4):556-560.
40. Téllez-Zenteno JF, Dhar R, Hernandez-Ronquillo L, Wiebe S. Long-term outcomes in epilepsy surgery: antiepileptic drugs, mortality, cognitive and psychosocial aspects. Brain. 2007;130(pt 2):334-345.
41. Lachhwani DK, Loddenkemper T, Holland KD, et al. Discontinuation of medications after successful epilepsy surgery in children. Pediatr Neurol. 2008;38 (5):340-344.
42. Hoppe C, Poepel A, Sassen R, Elger CE. Discontinuation of anticonvulsant medication after epilepsy surgery in children. Epilepsia. 2006;47(3):580-583.
43. Rathore C, Panda S, Sarma PS, Radhakrishnan K. How safe is it to withdraw antiepileptic drugs following successful surgery for mesial temporal lobe epilepsy? Epilepsia. 2011;52(3):627-635.
44. Schmidt D, Stavem K. Long-term seizure outcome of surgery versus no surgery for drug-resistant partial epilepsy: a review of controlled studies. Epilepsia. 2009;50(6): 1301-1309.
45. Wu JY, Salamon N, Kirsch HE, et al. Noninvasive testing, early surgery, and seizure freedom in tuberous sclerosis complex. Neurology. 2010;74(5):392-398.
46. Elsharkawy AE, Pietilä TA, Alabbasi AH, Pannek H, Ebner A. Long term outcome in patients not initially seizure free after resective epilepsy surgery. Seizure. 2011;20 (5):419-424.
47. Perry MS, Dunoyer C, Dean P, et al. Predictors of seizure freedom after incomplete resection in children. Neurology. 2010;75(16):1448-1453.