Polyamidoamine dendron-bearing lipid assemblies: Their morphologies and gene transfection ability

Journal of Biomaterials Applications

Volumn 27, Issue 4, 2012, Pages 445-456

  Iwashita, Shinki ^a   Hiramatsu, Yoshie ^a   Otani, Takayuki ^a   Amano, Chie ^a   Hirai, Masahiko ^a   Oie, Kazunori ^a   Yuba, Eiji ^b   Kono, Kenji ^b   Miyamoto, Masaaki ^c   Igarashi, Koichi ^a  

^a RandD Division   (Japan)

^b Osaka Prefecture University   (Japan)

^c KOBE UNIVERSITY   (Japan)

Author keywords

Assembly morphology; cationic liposome; lipoplexes; non viral vector; nucleic acids delivery; polyamidoamine dendron bearing lipid; transfection

Indexed keywords

CATIONIC LIPOSOMES; LIPOPLEXES; NONVIRAL VECTORS; POLYAMIDOAMINES; TRANSFECTION;

AGGLOMERATION; BIOMOLECULES; LIPIDS; MORPHOLOGY; NUCLEIC ACIDS; TRANSMISSION ELECTRON MICROSCOPY;

DENDRIMERS;

DENDRIMER; DNA; LIPID; PAMAM STARBURST;

ANIMAL; ARTICLE; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; GENETIC TRANSFECTION; GENETICS; HELA CELL; HUMAN; PLASMID; SYNTHESIS;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DENDRIMERS; DNA; HELA CELLS; HUMANS; LIPIDS; PLASMIDS; TRANSFECTION;

EID: 84868159365     PISSN: 08853282     EISSN: 15308022     Source Type: Journal    
DOI: 10.1177/0885328211411955     Document Type: Article

References (36)

1. Marshall E. Gene therapy death prompts review of adenovirus vector. Science. 1999 ; 286: 2244-2245
2. Marshall E. FDA halts all gene therapy trials at penn. Science. 2000 ; 287: 565-567
3. Marshall E. Gene therapy a suspect in leukemia-like disease. Science. 2002 ; 298: 34-35
4. Kaiser J. Seeking the cause of induced leukemias in X-SCID trial. Science. 2003 ; 299: 495-495
5. Hama S, Akita H, Iida S, Mizuguchi H, Harashima H. Quantitative and mechanism-based investigation of post-nuclear delivery events between adenovirus and lipoplex. Nucleic Acids Res. 2007 ; 35: 1533-1543
6. Zabner J, Fasbender AJ, Moninger T, Poellinger KA, Welsh MJ. Cellular and molecular barriers to gene transferby a cationic lipid. J Biol Chem. 1995 ; 270: 18997-9007-18997-9007
7. Brunner S, Sauer T, Carotta S, Cotton M, Saltik M, Wagner E. Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus. Gene Ther. 2000 ; 7: 401-407
8. Bielinska AU, Kukowska-Latallo JF, Baker JR. Theinteraction of plasmid DNA with polyamidoamine dendrimers mechanism of complex formation and analysis of alterations induced in nuclease sensitivity and transcriptional activity of the complexed DNA. Biochem Biophys Acta. 1997 ; 1353: 180-190
9. Van de Wetering P, Moret EE, Schuurmans-Nieuwenbroek ME, van Steenbergen MJ, Hennink WE. Structure-activity relationships of water-soluble cationic methacrylate/methacrylamide polymers for nonviral gene delivery. Bioconjugate Chem. 1999 ; 10: 589-597
10. Yamada Y, Nomura T, Harashima H, Yamashita A, Katoono R, Yui N. Intranuclear DNA release is a determinant of transfection activity for a non-viral vector: biocleavable polyrotaxane as a supramolecularly dissociative condenser for efficient intranuclear DNA release. Biol Pharm Bull. 2010 ; 33: 1218-1222
11. Colombo MG, Citti L, Basta G, Caterina RD, Biagini A, Rainaldi G. Differential ability of human endothelial cells to internalize and express exogenous DNA. Cardiovasc Drugs Ther. 2001 ; 15: 25-29
12. Parente RA, Nir S, Szoka FC. Mechanism of leakage of phospholipid vesicle contents induced by the peptide GALA. Biochemistry. 1990 ; 18: 8720-8728
13. Kakudo T, Chaki S, Futaki S, Nakase I, Akaji K, Kawakami T, et al. Transferrin-modified liposomes equipped with a pH-sensitive fusogenic peptide: an artificial viral-like delivery system. Biochemistry. 2004 ; 43: 5618-5628
14. Xu Y, Szoka FC. Mechanism of DNA release from cationic liposome/DNA complexes used in cell transfection. Biochemistry. 1996 ; 35: 5616-5623
15. Boussif O, Lezoualc'h F, Zanta MA, Mergny MD, Scherman D, Demeneix B, et al. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine. Proc Natl Acad Sci USA. 1995 ; 92: 7297-7301
16. Haensler J, Szoka FC. Polyamidoamine cascade polymers mediate efficient transfection of cells in culture. Bioconjugate Chem. 1993 ; 4: 372-379
17. Koynova R, Wang L, MacDonald RC. An intracellular lamellar-nonlamellar phase transition rationalizes the superior performance of some cationic lipid transfection agents. Proc Natl Acad Sci USA. 2006 ; 103: 14373-14378
18. Caracciolo G, Marchini C, Pozzi D, Caminiti R, Amenitsch H, Montani M, et al. Structural stability against disintegration by anionic lipids rationalizes theefficiency of cationic liposome/DNA complexes. Langmuir. 2007 ; 23: 8713-8717
19. Obata Y, Suzuki D, Takeoka S. Evaluation of cationic assemblies constructed with amino acid based lipids for plasmid DNA delivery. Bioconjugate Chem. 2008 ; 19: 1055-1063
20. Tros de Ilarduya C, Sun Y, Düzgüne N. Gene delivery by lipoplexes and polyplexes. Eur J Pharm Sci. 2010 ; 40: 159-170
21. Sonawana ND, Szoka FC, Verkman AS. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. J Biol Chem. 2003 ; 278: 44826-44831
22. Heinze M, Brezesinski G, Dobner B, Langner A. Novel cationic lipids based on malonic acid amides backbone: transfection efficacy and cell toxicity properties. Bioconjugate Chem. 2010 ; 21: 696-708
23. Takahashi T, Kono K, Itoh T, Emi N, Takagishi T. Synthesis of novel cationic lipids having polyamidoamine dendrons and their transfection activity. Bioconjugate Chem. 2003 ; 14: 764-773
24. Agrawal A, Min DH, Singh N, Zhu H, Birjiniuk A, von Maltzahn G, et al. Functional delivery of siRNA in mice using dendriworms. ACS Nano. 2009 ; 22: 2495-2504
25. Jones RA, Cheung CY, Black FE, Zia JK, Stayton PS, Hoffman AS, et al. Poly(2-alkylacrylic acid) polymers deliver molecules to the cytosol by pH-sensitive disruption of endosomal vesicles. Biochem J. 2003 ; 15: 65-75
26. Hu Y, Litwin T, Nagaraja AR, Kwong B, Katz J, Watson N, et al. Cytosolic delivery of membrane-impermeable molecules in dendritic cells using pH-responsive core-shell nanoparticles. Nano lett. 2007 ; 7: 3056-3064
27. Takahashi T, Harada A, Emi N, Kono K. Preparation of efficient gene carriers using a polyamidoamine dendron-bearing lipids: improvement of serum resistance. Bioconjugate Chem. 2005 ; 16: 1160-1165
28. Percec V, Wilson DA, Leowanawat P, Wilson CJ, Hughes AD, Kaucher MS, et al. Self-assembly of Janus dendrimers into uniform dendrimersomes and other complex architectures. Science. 2010 ; 21: 1009-1014
29. van Hest JC, Delnoye DA, Baars MW, van Genderen MH, Meijer EW. Polystyrene-dendrimer amphiphilicblock copolymers with a generation-dependent Aggregation. Science. 1995 ; 268: 1592-1595
30. Almgren M. Mixed micelles and other structures in the solubilization of bilayer lipid membranes by surfactants. Biochim Biophys Acta. 2000 ; 1508: 146-163
31. Niculescu-Duvaz D, Heyes J, Springer CJ. Structure-activity relationship in cationic lipid mediated gene transfection. Curr Med Chem. 2003 ; 10: 1233-1261
32. Almgren M, Edwards K, Karlsson G. Cryo transmission electron microscopy of liposomes and related structures. Coll Surf Physicochem Eng Aspects. 2000 ; 174: 3-21
33. Caracciolo G, Pozzi D, Caminiti R, Castellano AC. Structural characterization of a new lipid/DNA complex showing a selective transfection efficiency in ovarian cancer cells. Eur Phys J. 2003 ; E10: 331-336
34. Zhao QQ, Chen JL, Lv TF, He CX, Tang GP, Liang WQ, et al. N/P ratio significantly influences the transfection efficiency and cytotoxicity of a polyethylenimine/chitosan/DNA complex. Biol Pharm Bull. 2009 ; 32: 706-710
35. Rejman J, Oberle V, Zuhorn IS, Hoekstra D. Size-dependent internalization of particles via the pathways of clathrin-and caveolae-mediated endocytosis. Biochem J. 2004 ; 377: 159-169
36. Zelphati O, Szoka FC. Mechanism of oligonucleotide release from cationic Liposomes. Proc Natl Acad Sci USA. 1996 ; 93: 11493-11498