Cranial irradiation increases risk of stroke in pediatric brain tumor survivors

Stroke

Volumn 43, Issue 11, 2012, Pages 3035-3040

  Campen, Cynthia J ^a,b   Kranick, Sarah M ^a   Kasner, Scott E ^b   Kessler, Sudha K ^b   Zimmerman, Robert A ^a   Lustig, Robert ^c   Phillips, Peter C ^a,b   Storm, Phillip B ^a,b   Smith, Sabrina E ^a,b   Ichord, Rebecca ^a,b   Fisher, Michael J ^a,b  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

childhood brain tumors; stroke; treatment related stroke

Indexed keywords

AGE DISTRIBUTION; ARTICLE; BRAIN CIRCULUS ARTERIOSUS; BRAIN RADIATION; BRAIN TUMOR; CANCER RADIOTHERAPY; CANCER SURVIVAL; CANCER SURVIVOR; CEREBROVASCULAR ACCIDENT; CHILD; CHILDHOOD CANCER; COHORT ANALYSIS; CONTROLLED STUDY; DATA BASE; FEMALE; HUMAN; HYPOTHESIS; MAJOR CLINICAL STUDY; MALE; ONCOLOGY; PRIORITY JOURNAL; RADIATION EXPOSURE; RADIATION INJURY; RETROSPECTIVE STUDY; RISK ASSESSMENT; SCHOOL CHILD; TERTIARY HEALTH CARE; TRANSIENT ISCHEMIC ATTACK;

ADOLESCENT; BRAIN NEOPLASMS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; CRANIAL IRRADIATION; FEMALE; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; MALE; RETROSPECTIVE STUDIES; RISK FACTORS; STROKE; SURVIVORS; YOUNG ADULT;

EID: 84868159268     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.112.661561     Document Type: Article

References (33)

1. Crossen JR, Garwood D, Glatstein E, Neuwelt EA. Neurobehavioral sequelae of cranial irradiation in adults: a review of radiation-induced encephalopathy. J Clin Oncol. 1994;12:627-642.
2. Fouladi M, Gilger E, Kocak M, Wallace D, Buchanan G, Reeves C, et al. Intellectual and functional outcome of children 3 years old or younger who have CNS malignancies. J Clin Oncol. 2005;23:7152-7160.
3. Monje ML, Vogel H, Masek M, Ligon KL, Fisher PG, Palmer TD. Impaired human hippocampal neurogenesis after treatment for central nervous system malignancies. Ann Neurol. 2007;62:515-520.
4. Gurney JG, Kadan-Lottick NS, Packer RJ, Neglia JP, Sklar CA, Punyko JA, et al. Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors: Childhood Cancer Survivor Study. Cancer. 2003;97:663-673.
5. Burn S, Gunny R, Phipps K, Gaze M, Hayward R. Incidence of cavernoma development in children after radiotherapy for brain tumors.J Neurosurg. 2007;106:379-383.
6. Fouladi M, Lagston J, Mulhern R, Jones D, Xiong X, Yang J, et al. Silent lacunar lesions detected by magnetic resonance imaging of children with brain tumors: a late sequela of therapy. J Clin Oncol. 2000;18:824-883.
7. Belka C, Budach W, Kortmann RD, Bamberg M. Radiation induced CNS toxicity-molecular and cellular mechanisms. Br J Cancer. 2001;85:1233-1239.
8. Giglio P, Gilbert MR. Cerebral radiation necrosis. Neurologist. 2003;9:180-188.
9. Bitzer M, Topka H. Progressive cerebral occlusive disease after radiation therapy. Stroke. 1995;26:131-136.
10. Grenier Y, Tomita T, Marymont MH, Byrd S, Burrowes DM. Late postirradiation occlusive vasculopathy in childhood medulloblastoma. J Neurosurg. 1998;89:460-464.
11. Rogers LR. Cerebrovascular complications in cancer patients. Neurol Clin. 2003;21:167-192.
12. CBTRUS (2010). CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2004-2006. Central Brain Tumor Registry of the United States website. Available at: www.cbtrus.org. Accessed September 21, 2011.
13. Nishizawa S, Ryu H, Yokoyama T, Ninchoji T, Shimoyama I, Yamamoto S, et al. Post-irradiation vasculopathy of intracranial major arteries in children. Neurol Med Chir. 1991;31:336-341.
14. Muthukrishnan A, Bajoghli M, Mountz JM. Delayed development of radiation vasculopathy of the brain stem confirmed by F-18 FDG PET in a case of anaplastic astrocytoma. Clin Nucl Med. 2007;32:527-531.
15. Maher CO, Raffel C. Early vasculopathy following radiation in a child with medulloblastoma. Pediatr Neurosurg. 2000;32:255-258.
16. Brant-Zawadzki M, Anderson M, DeArmond SJ, Conley FK, Jahnke RW. Radiation-induced large vessel occlusive vasculopathy. AJR Am J Roentgenol. 1980;134:51-55.
17. Epstein MA, Packer RJ, Rorke LB, Zimmerman RA, Goldwein JW, Sutton LN, et al. Vascular malformation with radiation vasculopathy after treatment of chiasmatic/hypothalamic glioma. Cancer. 1992;70:887-893.
18. Penagaricano JA, Linskey ME, Ratanatharathorn V. Accelerated cerebral vasculopathy after radiation therapy to the brain. Neurol India. 2004;52:482-486.
19. Salih ISM, Higgins NJN, Warburton EA, Baron JC. Lacunar stroke attributable to radiation-induced intracranial arteriopathy. Eur J Neurol. 2007;14:937-939.
20. Omura M, Aida N, Sekido K, Kakehi M, Matsubara S. Large intracranial vessel occlusive vasculopathy after radiation therapy in children: clinical features and usefulness of magnetic resonance imaging. Int J Radiat Oncol Biol Phys. 1997;38:241-249.
21. Bowers DC, Liu Y, Leisenring W, McNeil E, Stovall M, Gurney JG, et al. Late occurring stroke among long-term survivors of childhood leukemia and brain tumors: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2006;24:5277-5282.
22. Ullrich NJ, Robertson R, Kinnamon DD, Scot RM, Kieran MW, Turner CD, et al. Moyamoya following cranial irradiation for primary brain tumors in children. Neurology. 2007;68:932-938.
23. Bowers DC, Mulne AF, Reisch JS, Elterman Rd, Munoz L, Booth T, et al. Nonperioperative strokes in children with central nervous system tumors. Cancer. 2002;94:1094-1101.
24. Haddy N, Mousannif A, Tukenova M, Guibout C, Grill J, Dhermain F, et al. Relationship between the brain radiation dose for the treatment of childhood cancer and the risk of long-term cerebrovascular mortality. Brain. 2011;134:1362-1372.
25. Shellhaas RA, Smith SE, O'Toole E, Licht DJ, Ichord RN. Mimics of childhood stroke: characteristics of a prospective cohort. Pediatrics. 2006;118:704-709.
26. Hilal SK, Solomon GE, Gold AP, Carter S. Primary cerebral arterial occlusive disease in children: Part II. Neurocutaneous syndromes. Radiology. 1971;99:87-93.
27. Rosser TL, Vezina G, Packer RJ. Cerebrovascular abnormalities in a population of children with neurofibromatosis type 1. Neurology. 2005;8:553-555.
28. Agarwal NS, Johnston C, Wu YW, Sidney S, Fullerton HJ. Imaging data reveal a higher pediatric stroke incidence than prior US estimates. Stroke. 2009;40:3415-3421.
29. Lynch JK, Hirtz DG, deVeber G, Nelson KB. Report of the National Institute of Neurological Disorders and Stroke workshop on perinatal and childhood stroke. Pediatrics. 2002;109:116-123.
30. Monje ML, Palmer T. Radiation injury and neurogenesis. Curr Opin Neurol. 2003;16:129-134.
31. Bowers DC, McNeil DE, Liu Y, Yasui Y, Stovall M, Gurney JG, et al. Stroke as a late treatment effect of Hodgkin's disease: a report from the Childhood Cancer Survivor Study. J Clin Oncol. 2005;23:6508-6515.
32. Meattini I, Scotti V, Pescini F, Livi L, Sulprizio S, Palumbo V, et al. Ischemic stroke during cisplatin-based chemotherapy for testicular germ cell tumor: case report and review of the literature. J Chemother. 2010;22:134-136.
33. Li SH, Chen WH, Tang Y, Rau KM, Chen YY, Huang TL, et al. Incidence of ischemic stroke post-chemotherapy: a retrospective review of 10,963 patients. Clin Neurol Neurosurg. 2006;108:150-156.