메뉴 건너뛰기




Volumn 28, Issue 6, 2012, Pages 2131-2137

1,25-dihydroxyvitamin D3 inhibits growth of the breast cancer cell line MCF-7 and downregulates cytochrome P4501B1 through the COX-2/PGE2 pathway

Author keywords

1,25 dihydroxyvitamin D3; Breast cancer; COX 2 PGE2 pathway; Cytochrome P4501B1

Indexed keywords

CALCITRIOL; CYCLOOXYGENASE 2; CYTOCHROME P450 1B1; ESTROGEN RECEPTOR ALPHA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN E2;

EID: 84868142199     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.2031     Document Type: Conference Paper
Times cited : (31)

References (20)
  • 2
    • 67349103053 scopus 로고    scopus 로고
    • Vitamin D and breast cancer
    • Bertone-Johnson ER: Vitamin D and breast cancer. Ann Epidemiol 19:462-467, 2009.
    • (2009) Ann Epidemiol , vol.19 , pp. 462-467
    • Bertone-Johnson, E.R.1
  • 4
    • 77954760178 scopus 로고    scopus 로고
    • Vitamin D and breast cancer: Inhibition of estrogen synthesis and signaling
    • Krishnan AV, Swami S and Feldman D: Vitamin D and breast cancer: inhibition of estrogen synthesis and signaling. J Steroid Biochem Mol Biol 121:343-348, 2010.
    • (2010) J Steroid Biochem Mol Biol , vol.121 , pp. 343-348
    • Krishnan, A.V.1    Swami, S.2    Feldman, D.3
  • 5
    • 41249097591 scopus 로고    scopus 로고
    • EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells. Evidence of a BRCA1 and p300 exchange
    • Subbaramaiah K, Hudis C, Chang SH, Hla T and Dannenberg AJ: EP2 and EP4 receptors regulate aromatase expression in human adipocytes and breast cancer cells. Evidence of a BRCA1 and p300 exchange. J Biol Chem 283:3433-3444, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 3433-3444
    • Subbaramaiah, K.1    Hudis, C.2    Chang, S.H.3    Hla, T.4    Dannenberg, A.J.5
  • 6
    • 77951567623 scopus 로고    scopus 로고
    • Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERα pathway in human breast cancer cells
    • Han EH, Kim HG, Hwang YP, Song GY and Jeong HG: Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERα pathway in human breast cancer cells. Toxicol Sci 114:204-216, 2010.
    • (2010) Toxicol Sci , vol.114 , pp. 204-216
    • Han, E.H.1    Kim, H.G.2    Hwang, Y.P.3    Song, G.Y.4    Jeong, H.G.5
  • 7
    • 0036782045 scopus 로고    scopus 로고
    • Effects of estrogenic compounds on immunoglobulin production by mouse splenocytes
    • DOI 10.1248/bpb.25.1263
    • Han D, Denison MS, Tachibana H and Yamada K: Effects of estrogenic compounds on immunoglobulin production by mouse splenocytes. Biol Pharm Bull 25:1263-1267, 2002. (Pubitemid 39663182)
    • (2002) Biological and Pharmaceutical Bulletin , vol.25 , Issue.10 , pp. 1263-1267
    • Han, D.1    Denison, M.S.2    Tachibana, H.3    Yamada, K.4
  • 8
    • 67650151005 scopus 로고    scopus 로고
    • Cancer-related inflammation, the seventh hallmark of cancer: Links to genetic instability
    • Colotta F, Allavena P, Sica A, Garlanda C and Mantovani A: Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability. Carcinogenesis 30:1073-1081, 2009
    • (2009) Carcinogenesis , vol.30 , pp. 1073-1081
    • Colotta, F.1    Allavena, P.2    Sica, A.3    Garlanda, C.4    Mantovani, A.5
  • 10
    • 33748578972 scopus 로고    scopus 로고
    • Expression of COX-2 and steroid converting enzymes in breast cancer
    • Gunnarsson C, Jansson A, Holmlund B, et al: Expression of COX-2 and steroid converting enzymes in breast cancer. Oncol Rep 16:219-224, 2006.
    • (2006) Oncol Rep , vol.16 , pp. 219-224
    • Gunnarsson, C.1    Jansson, A.2    Holmlund, B.3
  • 11
    • 1942443627 scopus 로고    scopus 로고
    • Analysis of Vitamin D-Regulated Gene Expression in LNCaP Human Prostate Cancer Cells Using cDNA Microarrays
    • DOI 10.1002/pros.20006
    • Krishnan AV, Shinghal R, Raghavachari N, Brooks JD, Peehl DM and Feldman D: Analysis of vitamin D-regulated gene expression in LNCaP human prostate cancer cells using cDNA microarrays. Prostate 59:243-251, 2004 (Pubitemid 38509756)
    • (2004) Prostate , vol.59 , Issue.3 , pp. 243-251
    • Krishnan, A.V.1    Shinghal, R.2    Raghavachari, N.3    Brooks, J.D.4    Peehl, D.M.5    Feldman, D.6
  • 12
    • 73649116021 scopus 로고    scopus 로고
    • Tissue-selective regulation of aromatase expression by calcitriol: Implications for breast cancer therapy
    • Krishnan AV, Swami S, Peng L, Wang J, Moreno J and Feldman D: Tissue-selective regulation of aromatase expression by calcitriol: implications for breast cancer therapy. Endocrinology 151:32-42, 2010.
    • (2010) Endocrinology , vol.151 , pp. 32-42
    • Krishnan, A.V.1    Swami, S.2    Peng, L.3    Wang, J.4    Moreno, J.5    Feldman, D.6
  • 13
    • 24744452645 scopus 로고    scopus 로고
    • Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells
    • DOI 10.1158/0008-5472.CAN-05-1435
    • Moreno J, Krishnan AV, Swami S, Nonn L, Peehl DM and Feldman D: Regulation of prostaglandin metabolism by calcitriol attenuates growth stimulation in prostate cancer cells. Cancer Res 65:7917-7925, 2005 (Pubitemid 41297270)
    • (2005) Cancer Research , vol.65 , Issue.17 , pp. 7917-7925
    • Moreno, J.1    Krishnan, A.V.2    Swami, S.3    Nonn, L.4    Peehl, D.M.5    Feldman, D.6
  • 14
    • 62349138124 scopus 로고    scopus 로고
    • The COX-2/PGE2 pathway: Key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
    • Greenhough A, Smartt HJ, Moore AE, et al: The COX-2/PGE2 pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment. Carcinogenesis 30:377-386, 2009
    • (2009) Carcinogenesis , vol.30 , pp. 377-386
    • Greenhough, A.1    Smartt, H.J.2    Moore, A.E.3
  • 16
    • 0035134504 scopus 로고    scopus 로고
    • Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway
    • DOI 10.1210/me.15.1.32
    • Feng W, Webb P, Nguyen P, et al: Potentiation of estrogen receptor activation function 1 (AF-1) by Src/JNK through a serine 118-independent pathway. Mol Endocrinol 15:32-45, 2001. (Pubitemid 32156039)
    • (2001) Molecular Endocrinology , vol.15 , Issue.1 , pp. 32-45
    • Feng, W.1    Webb, P.2    Nguyen, P.3    Liu, X.4    Li, J.5    Karin, M.6    Kushner, P.J.7
  • 17
    • 0032906876 scopus 로고    scopus 로고
    • Phosphorylation of human estrogen receptor α by protein kinase A regulates dimerization
    • Chen D, Pace PE, Coombes RC and Ali S: Phosphorylation of human estrogen receptor α by protein kinase A regulates dimerization. Mol Cell Biol 19:1002-1015, 1999 (Pubitemid 29046844)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.2 , pp. 1002-1015
    • Chen, D.1    Pace, P.E.2    Coombes, R.C.3    Ali, S.4
  • 19
    • 34249930470 scopus 로고    scopus 로고
    • Targeting cytochrome P450 enzymes: A new approach in anti-cancer drug development
    • DOI 10.1016/j.bmc.2007.05.046, PII S0968089607004622
    • Bruno RD and Njar VC: Targeting cytochrome P450 enzymes: a new approach in anti-cancer drug development. Bioorg Med Chem 15:5047-5060, 2007 (Pubitemid 46880385)
    • (2007) Bioorganic and Medicinal Chemistry , vol.15 , Issue.15 , pp. 5047-5060
    • Bruno, R.D.1    Njar, V.C.O.2
  • 20
    • 2342516193 scopus 로고    scopus 로고
    • Human CYP1B1 Is Regulated by Estradiol via Estrogen Receptor
    • DOI 10.1158/0008-5472.CAN-04-0166
    • Tsuchiya Y, Nakajima M, Kyo S, Kanaya T, Inoue M and Yokoi T: Human CYP1B1 is regulated by estradiol via estrogen receptor. Cancer Res 64:3119-3125, 2004 (Pubitemid 38581412)
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 3119-3125
    • Tsuchiya, Y.1    Nakajima, M.2    Kyo, S.3    Kanaya, T.4    Inoue, M.5    Yokoi, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.