Differential HIV-1 endocytosis and susceptibility to virus infection in human macrophages correlate with cell activation status

Journal of Virology

Volumn 86, Issue 19, 2012, Pages 10399-10407

  Gobeil, Lise Andrée ^a   Lodge, Robert ^a,b   Tremblay, Michel J ^a,b  

^a LAVAL UNIVERSITY   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CLATHRIN; GAMMA INTERFERON; INTERLEUKIN 4; LIPOPOLYSACCHARIDE;

ANTIGEN BINDING; ARTICLE; CELL ACTIVATION; ENDOCYTOSIS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; M1 ACTIVATED MACROPHAGE; M2A ACTIVATED MACROPHAGE; MACROPHAGE; MONOCYTE; MONOCYTE DERIVED MACROPHAGE; PRIORITY JOURNAL; VIRAL PHENOMENA AND FUNCTIONS; VIRUS ATTACHMENT; VIRUS DEGRADATION; VIRUS INFECTIVITY;

ANTIGENS, CD4; CELL MEMBRANE; CELL SURVIVAL; CLATHRIN; ENDOCYTOSIS; ENDOSOMES; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HELA CELLS; HIV INFECTIONS; HIV-1; HUMANS; MACROPHAGES; MODELS, GENETIC; RECEPTORS, CCR5;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84868130969     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01051-12     Document Type: Article

References (41)

1. Baldwin CL, Jiang X, Fernandes DM. 1993. Macrophage control of Brucella abortus: influence of cytokines and iron. Trends Microbiol. 1:99-104.
2. Bosch B, et al. 2008. A clathrin-dynamin-dependent endocytic pathway for the uptake of HIV-1 by direct T cell-T cell transmission. Antiviral Res. 80:185-193.
3. Bounou S, Leclerc JE, Tremblay MJ. 2002. Presence of host ICAM-1 in laboratory and clinical strains of human immunodeficiency virus type 1 increases virus infectivity and CD4(+)-T-cell depleti on in human lymphoid tissue, a major site of replication in vivo. J. Virol. 76:1004-1014.
4. Bourinbaiar AS, Phillips DM. 1991. Transmission of human immunodeficiency virus from monocytes to epithelia. J. Acquir. Immune Defic.Syndr. 4:56-63.
5. Bowman EJ, Siebers A, Altendorf K. 1988. Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plan
6. Carter GC, Bernstone L, Baskaran D, James W. 2011. HIV-1 infects macrophages by exploiting an endocytic route dependent on dynamin, Rac1 and Pak1. Virology. 409:234-250.
7. Cassol E, Cassetta L, Rizzi C, Alfano M, Poli G. 2009. M1 and M2a polarization of human monocyte-derived macrophages inhibits HIV-1 replication by distinct mechanisms. J. Immunol. 182:6237-6246.
8. Connor RI, Chen BK, Choe S, Landau NR. 1995. Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology 206:935-944.
9. Daecke J, Fackler OT, Dittmar MT, Krausslich HG. 2005. Involvement of clathrin-mediated endocytosis in human immunodeficiency virus type 1 entry. J. Virol. 79:1581-1594.
10. de la Vega M, et al. 2011. Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusion. Retrovirology 8:99.
11. Dornadula G, Zhang H, Shetty S, Pomerantz RJ. 1999. HIV-1 virionsproduced from replicating peripheral blood lymphocytes are more infectious than those from nonproliferating macrophages due to higher levels of intravirion reverse transcripts: implications for pathogenesis and transmission. Virology 253:10-16.
12. Fernandez-Boyanapalli R, et al. 2010. Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-gamma in a nitric oxide-dependent manner. J. Immunol. 185:4030-4041.
13. Gordon S. 2003. Alternative activation of macrophages. Nat. Rev. Immunol. 3:23-35.
14. Herbein G, Varin A. 2010. The macrophage in HIV-1 infection: from activation to deactivation?. Retrovirology 7:33.
15. Janas AM, Dong C, Wang JH, Wu L. 2008. Productive infection of human immunodeficiency virus type 1 in dendritic cells requires fusionmediated viral entry. Virology 375:442-451.
16. Lifson JD, Reyes GR, McGrath MS, Stein BS, Engleman EG. 1986. AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen. Science 232:1123-1127.
17. Mackaness GB. 1964. The immunological basis of acquired cellular resistance. J. Exp. Med. 120:105-120.
18. Mantovani A, et al. 2004. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol. 25:677-686.
19. Maréchal V, Clavel F, Heard JM, Schwartz O. 1998. Cytosolic Gag p24 as an index of productive entry of human immunodeficiency virus type 1. J. Virol. 72:2208-2212.
20. Maréchal V, et al. 2001. Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis. J. Virol. 75:11166-11177.
21. McClure MO, Marsh M, Weiss RA. 1988. Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism. EMBO J. 7:513-518.
22. Miyauchi K, Kim Y, Latinovic O, Morozov V, Melikyan GB. 2009. HIV enters cells via endocytosis and dynamin-dependent fusion with endosomes. Cell 137:433-444.
23. Montaner LJ, et al. 1999. Type 1 and type 2 cytokine regulation of macrophage endocytosis: differential activation by IL-4/IL-13 as opposed to IFN-gamma or IL-10. J. Immunol. 162:4606-4613.
24. Mosser DM. 2003. The many faces of macrophage activation. J. Leukoc. Biol. 73:209-212.
25. Ouellet M, Roy J, Barbeau B, Geleziunas R, Tremblay MJ. 2003. NF-kappaB induction by bisperoxovanadium compounds requires CD45, p36(LAT), PKC, and IKK activity and exhibits kinetics of activation comparable to those of TCR/CD28 coengagement. Biochemistry 42:8260-8271.
26. Pai RK, Askew D, Boom WH, Harding CV. 2002. Regulation of class II MHC expression in APCs: roles of types I, III, and IV class II transactivator. J. Immunol. 169:1326-1333.
27. Pauza CD, Price TM. 1988. Human immunodeficiency virus infection of T cells and monocytes proceeds via receptor-mediated endocytosis. J. Cell Biol. 107:959-968.
28. Permanyer M, Ballana E, Este JA. 2010. Endocytosis of HIV: anything goes. Trends Microbiol. 18:543-551.
29. Platt EJ, Wehrly K, Kuhmann SE, Chesebro B, Kabat D. 1998. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J. Virol. 72:2855-2864.
30. Schaeffer E, Soros VB, Greene WC. 2004. Compensatory link between fusion and endocytosis of human immunodeficiency virus type 1 in human CD4 T lymphocytes. J. Virol. 78:1375-1383.
31. Schuitemaker H, et al. 1992. Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages. J. Clin. Invest. 89:1154-1160.
32. Shaughnessy LM, Swanson JA. 2007. The role of the activated macrophage in clearing Listeria monocytogenes infection. Front. Biosci. 12:2683-2692.
33. Smith AE, Helenius A. 2004. How viruses enter animal cells. Science 304:237-242.
34. Souza KL, Elsner M, Mathias PC, Lenzen S, Tiedge M. 2004. Cytokines activate genes of the endocytotic pathway in insulin-producing RINm5F cells. Diabetologia 47:1292-1302.
35. Stein BS, et al. 1987. pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane. Cell 49:659-668.
36. Vidricaire G, Imbeault M, Tremblay MJ. 2004. Endocytic host cell machinery plays a dominant role in intracellular trafficking of incoming human immunodeficiency virus type 1 in human placental trophoblasts. J. Virol. 78:11904-11915.
37. Vidricaire G, Tremblay MJ. 2007. A clathrin, caveolae, and dynaminindependent endocytic pathway requiring free membrane cholesterol drives HIV-1 internalization and infection in polarized trophoblastic cells. J. Mol. Biol. 368:1267-1283.
38. Wang J, Roderiquez G, Oravecz T, Norcross MA. 1998. Cytokine regulation of human immunodeficiency virus type 1 entry and replication in human monocytes/macrophages through modulation of CCR5 expression. J. Virol. 72:7642-7647.
39. Wei X, et al. 2002. Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrob. Agents Chemother. 46:1896-1905.
40. Wu L, KewalRamani VN. 2006. Dendritic-cell interactions with HIV: infection and viral dissemination. Nat. Rev. Immunol. 6:859-868.s
41. Zhao B, et al. 2006. Constitutive receptor-independent low density lipoprotein uptake and cholesterol accumulation by macrophages differentiated from human monocytes with macrophage-colony-stimulating factor (M-CSF). J. Biol. Chem. 281:15757-15762.