Bile salts increase epithelial cell proliferation through HuR-induced c-Myc expression

Journal of Surgical Research

Volumn 178, Issue 1, 2012, Pages 155-164

  Perrone, Erin E ^a,b   Liu, Lan ^a   Turner, Douglas J ^a   Strauch, Eric D ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

c Myc; HuR; Intestinal injury; Mucosal integrity; Proliferation; Taurodeoxycholic acid (TDCA)

Indexed keywords

BILE SALT; HUR PROTEIN; MESSENGER RNA; MYC PROTEIN; SMALL INTERFERING RNA; TAURODEOXYCHOLIC ACID;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; CRITICAL ILLNESS; CYTOPLASM; EPITHELIUM CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN TRANSPORT; REGULATORY MECHANISM;

3' UNTRANSLATED REGIONS; ANIMALS; BILE ACIDS AND SALTS; CELL LINE; CELL PROLIFERATION; CYTOPLASM; ENTEROCYTES; EPITHELIAL CELLS; GENE EXPRESSION; HU PARANEOPLASTIC ENCEPHALOMYELITIS ANTIGENS; INTESTINAL MUCOSA; MALE; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER; RNA, SMALL INTERFERING; TAURODEOXYCHOLIC ACID;

EID: 84868124390     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.02.029     Document Type: Article

References (44)

1. C.S. Potten, C. Booth, and D.M. Pritchard The intestinal epithelial stem cell: The mucosal governor Int J Exp Pathol 78 1997 219
2. C.S. Potten Epithelial cell growth and differentiation. II. Intestinal apoptosis Am J Physiol 273 1997 G253
3. A.F. Hofmann Intesinal absorption of bile acids and biliary constituents L.R. Johnson, Physiology of the gastrointestinal tract 1994 Raven Press New York 1845
4. K. Cheng, and J.P. Raufman Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors Biochem Pharmacol 70 2005 1035
5. J.D. Martinez, E.D. Stratagoules, and J.M. LaRue Different bile acids exhibit distinct biological effects: The tumor promoter deoxycholic acid induces apoptosis and the chemopreventive agent ursodeoxycholic acid inhibits cell proliferation Nutr Cancer 31 1998 111
6. V. D'Addio, J.M. Sayles, and C. Alvarez Bile: A trophic factor for rabbit esophageal epithelium in vitro Surg Forum 647 1996 125
7. W.D. Ford, J.E. De Vries, and J.S. Ross Effect of luminal contents on postresectional longitudinal and mucosal growth in the ileum of suckling rats Surgery 98 1985 935
8. R.C. Williamson, F.L. Bauer, and J.S. Ross Contributions of bile and pancreatic juice to cell proliferation in ileal mucosa Surgery 83 1978 570
9. M.Y. Al-Mukhtar, G.R. Sagor, and M.A. Ghatei The role of pancreatico-biliary secretions in intestinal adaptation after resection, and its relationship to plasma enteroglucagon Br J Surg 70 1983 398
10. J.S. Thompson, and D.C. Ferguson Effect of the distal remnant on ileal adaptation J Gastrointest Surg 4 2000 430
11. C.C. Roy, G. Laurendeau, and G. Doyon The effect of bile and of sodium taurocholate on the epithelial cell dynamics of the rat small intestine Proc Soc Exp Biol Med 149 1975 1000
12. M. Sayan, A. Alponat, and N. Yavuz The effect of oral sodium taurocholate on endotoxemia and intestinal anastomotic wound healing in rats with obstructive jaundice Surg Today 27 1997 953
13. E.D. Strauch, J.Y. Wang, and B.L. Bass Bile salt stimulates intestinal epithelial cell migration through TGF-beta after wounding J Surg Res 97 2001 49
14. E.D. Strauch, B.L. Bass, and J.N. Rao NF-kappaB regulates intestinal epithelial cell and bile salt-induced migration after injury Ann Surg 237 2003 494
15. A. Toledo, J. Yamaguchi, and J.Y. Wang Taurodeoxycholate stimulates intestinal cell proliferation and protects against apoptotic cell death through activation of NF-kappaB Dig Dis Sci 49 2004 1664
16. J. Yamaguchi, A. Toledo, and B.L. Bass Taurodeoxycholate increases intestinal epithelial cell proliferation through c-myc expression Surgery 135 2004 215
17. K.B. Marcu, S.A. Bossone, and A.J. Patel myc function and regulation Annu Rev Biochem 61 1992 809
18. H.E. Varmus The molecular genetics of cellular oncogenes Annu Rev Genet 18 1984 553
19. R. Heikkila, G. Schwab, and E. Wickstrom A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1 Nature 328 1987 445
20. J.T. Holt, R.L. Redner, and A.W. Nienhuis An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation Mol Cell Biol 8 1988 963
21. L.M. Facchini, and L.Z. Penn The molecular role of Myc in growth and transformation: Recent discoveries lead to new insights FASEB J 12 1998 633
22. B. Amati, M.W. Brooks, and N. Levy Oncogenic activity of the c-Myc protein requires dimerization with Max Cell 72 1993 233
23. B. Amati, T.D. Littlewood, and G.I. Evan The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max EMBO J 12 1993 5083
24. E.M. Blackwood, B. Luscher, and R.N. Eisenman Myc and Max associate in vivo Genes Dev 6 1992 71
25. C.M. Brennan, and J.A. Steitz HuR and mRNA stability Cell Mol Life Sci 58 2001 266
26. M. Gorospe HuR in the mammalian genotoxic response: Post-transcriptional multitasking Cell Cycle 2 2003 412
27. I.E. Gallouzi, and J.A. Steitz Delineation of mRNA export pathways by the use of cell-permeable peptides Science 294 2001 1895
28. K. Mazan-Mamczarz, S. Galban, and I. Lopez de Silanes RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation Proc Natl Acad Sci U S A 100 2003 8354
29. T. Zou, K. Mazan-Mamczarz, and J.N. Rao Polyamine depletion increases cytoplasmic levels of RNA-binding protein HuR leading to stabilization of nucleophosmin and p53 mRNAs J Biol Chem 281 2006 19387
30. A. Quaroni, J. Wands, and R.L. Trelstad Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria J Cell Biol 80 1979 248
31. U.K. Laemmli Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 227 1970 680
32. W.J. Ma, S. Cheng, and C. Campbell Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein J Biol Chem 271 1996 8144
33. L. Tao, P.M. Kramer, and W. Wang Altered expression of c-myc, p16 and p27 in rat colon tumors and its reversal by short-term treatment with chemopreventive agents Carcinogenesis 23 2002 1447
34. C.D. Davis, and E.G. Snyderwine Analysis of EGFR, TGF-alpha, neu and c-myc in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary tumors using RT-PCR Carcinogenesis 16 1995 3087
35. L. Xiao, J.N. Rao, and T. Zou Polyamines regulate the stability of activating transcription factor-2 mRNA through RNA-binding protein HuR in intestinal epithelial cells Mol Biol Cell 18 2007 4579
36. L.R. Johnson Regulation of gastrointestinal mucosal growth Physiol Rev 68 1988 456
37. E.D. Strauch, J. Yamaguchi, and B.L. Bass Bile salts regulate intestinal epithelial cell migration by nuclear factor-kappa B-induced expression of transforming growth factor-beta J Am Coll Surg 197 2003 974
38. M. Heinonen, P. Bono, and K. Narko Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma Cancer Res 65 2005 2157
39. R. Gryfe, C. Swallow, and B. Bapat Molecular biology of colorectal cancer Curr Probl Cancer 21 1997 233
40. J.G. Christensen, T.L. Goldsworthy, and R.C. Cattley Dysregulation of apoptosis by c-myc in transgenic hepatocytes and effects of growth factors and nongenotoxic carcinogens Mol Carcinog 25 1999 273
41. G. Yander, H. Halsey, and M. Kenna Amplification and elevated expression of c-myc in a chemically induced mouse colon tumor Cancer Res 45 1985 4433
42. G.G. Finley, N.T. Schulz, and S.A. Hill Expression of the myc gene family in different stages of human colorectal cancer Oncogene 4 1989 963
43. K. Cheng, and J.P. Raufman Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors Biochem Pharmacol 70 2005 1035
44. D.J. Turner, S.M. Alaish, and T. Zou Bile salts induce resistance to apoptosis through NF-kappaB-mediated XIAP expression Ann Surg 245 2007 415