Trans-resveratrol in nutraceuticals: Issues in retail quality and effectiveness

Molecules

Volumn 17, Issue 10, 2012, Pages 12393-12405

  Rossi, Damiano ^a   Guerrini, Alessandra ^a   Bruni, Renato ^b   Brognara, Eleonora ^a   Borgatti, Monica ^a   Gambari, Roberto ^a   Maietti, Silvia ^a   Sacchetti, Gianni ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF PARMA   (Italy)

Author keywords

Dietary supplements; Food supplements; Nutraceuticals; Quality control; Resveratrol

Indexed keywords

ANTIOXIDANT; BIFLAVONOID; CATECHIN; FLAVONOID; POLYPHENOL; PROANTHOCYANIDIN; PROCYANIDIN; RESVERATROL; STILBENE DERIVATIVE;

ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN K 562; COMMERCIAL PHENOMENA; CYTOLOGY; DIET SUPPLEMENTATION; DISCRIMINANT ANALYSIS; DRUG EFFECT; ERYTHROID CELL; FOOD PACKAGING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; REGRESSION ANALYSIS; STANDARD;

ANTIOXIDANTS; BIFLAVONOIDS; CATECHIN; CELL DIFFERENTIATION; CELL PROLIFERATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COMMERCE; DIETARY SUPPLEMENTS; DISCRIMINANT ANALYSIS; ERYTHROID CELLS; FLAVONOIDS; FOOD LABELING; HUMANS; K562 CELLS; LEAST-SQUARES ANALYSIS; POLYPHENOLS; PROANTHOCYANIDINS; STILBENES;

EID: 84868120047     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules171012393     Document Type: Article

References (34)

1. Hooyenga, P.A.; Witkamp, R.F.; Groen, K. Herbal products: Marketing strategies and legislation. Int. J. Green Pharm. 2009, 3, 270-276.
2. Morris, C.A. Internet marketing of herbal products. JAMA 2003, 290, 1505-1509.
3. Bech-Larsen, T.; Grunert, K.G. The perceived healthiness of functional foods: A conjoint study of Danish, Finnish and American consumers perception of functional foods. Appetite 2003, 40, 9-14.
4. Bagchi, D. Nutraceuticals and functional foods regulations in the United States and around the world. Toxicology 2006, 221, 1-3.
5. Zhao, J. Nutraceuticals, Nutritional Therapy, Phytonutrients, and Phytotherapy for Improvement of Human Health: A Perspective on Plant Biotechnology Application. Rec. Pat. Biotechnol. 2007, 1, 75-97.
6. European Pharmacopoeia. Commission directive 2003/63/EC. Off. J. Eur. Un. 2003, L159/46-L159/94.
7. Boniglia, C.; Carratù, B.; Gargiulo, R.; Giammarioli, S.; Mosca, M.; Sanzini, E. Content of phytoestrogens in soy-based dietary supplements. Food Chem. 2009, 11 5, 1389-1392.
8. Cassinese, C.; De Combarieu, E.; Falzoni, M.; Fuzzati, N.; Pace, R.; Sardone, N. New liquid chromatography method with ultraviolet detection for analysis of anthocyanins and anthocyanidins in Vaccinium myrtillus fruit dry extracts and commercial preparations. J. AOAC Int. 2007, 90, 911-919.
9. Lockwood, G.B. The quality of commercially available nutraceutical supplements and food sources. J. Pharm. Pharmacol. 2011, 63, 3-10.
10. Renaud, S.; de Lorgeril, M. Wine, Alcohol, Platelets, And the French paradox for coronary heart disease. Lancet 1992, 8808, 1523-1526.
11. Jerkovic, V.; Collin, S. Occurrence of resveratrol and piceid in American and European hop cones. J. Agric. Food Chem. 2007, 55, 8754-8758.
12. Alarcon De la Lastra, C.A.; Villegas, I. Resveratrol as an anti-inflammatory and anti-aging agent: mechanisms and clinical implications. Mol. Nutr. Food Res. 2005, 49, 405-430.
13. Baur, J.; Sinclair, D. Therapeutic potential of resveratrol: The in vivo evidence. Nat. Rev. Drug Disc. 2006, 5, 493-506.
14. Scott, E.; Steward, W.P.; Gescher, A.J.; Brown, K. Resveratrol in human cancer chemoprevention\Choosing the "right" dose. Mol. Nutr. Food Res. 2012, 56, 7-13.
15. Signorelli, P.; Ghidoni, R. Resveratrol as an anticancer nutrient: Molecular basis, Open questions and promises. J. Nutr. Biochem. 2005, 16, 449-466.
16. Smoliga, J.M.; Baur, J.; Hausenblas, H. Resveratrol and health\A comprehensive review of human clinical trials. Mol. Nutr. Food Res. 2011, 55, 1129-1141.
17. Szkudelska, K.; Szkudelski, T. Resveratrol, Obesity and diabetes. Eur. J. Pharmacol. 2010, 635, 1-8.
18. Vang, O.; Ahmad, N.; Baile, C.; Baur, J.; Brown, K.; Csiszar, A.; Das, D.K.; Delmas, D.; Gottfried, C.; Lin, H.; et al. What is new for an old molecule? Systematic review and recommendations on the use of resveratrol. PLoS One 2011, 6, e19881.
19. Juan, M.E.; Alfaras, I.; Planas, J.M. Colorectal cancer chemoprevention by trans-resveratrol. Pharm. Res. 2012, 65, 584-591.
20. Timmers, S.; Konings, E.; Bilet, L.; Houtkooper, R.H.; van de Weijer, T.; Goossens, G.H.; Hoeks, J.; van der Krieken, S.; Ryu, D.; Kersten, S.; et al. Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans. Cell Metab. 2011, 14, 612-622.
21. Trela, B.C.; Waterhouse, A.L. Resveratrol: Isomeric molar absorptivities and stability. J. Agric. Food Chem. 1996, 44, 1253-1257.
22. Bertelli, A.A.; Giovannini, L.; Bernini, W.; Migliori, M.; Fregoni, M.; Bavaresco, L.; Bertelli, A. Antiplatelet activity of cis-resveratrol. Drugs Exp. Clin. Res. 1996, 22, 61-63.
23. Reagan-Shaw, S.; Nihal, M.; Ahmad, N. Dose translation from animal to human studies revisited. FASEB J. 2008, 22, 659-661.
24. Athar, M.; Back, J.H.; Tang, X.; Kim, K.H.; Kopelovich, L.; Bickers, R.; Kim, A.L. Resveratrol: A review of pre-clinical studies for human cancer prevention. Toxicol. Appl. Pharmacol. 2007, 224, 274-283.
25. Rodriguez, C.M.; Arous, N.; Bachir, D.; Smith-Ravin, J.; Romeo, P.H.; Galacteros, F.; Garel, M. C. Resveratrol, A natural dietary phytoalexin, Possesses similar properties to hydroxyurea towards erythroid differentiation. Br. J. Haematol. 2001, 113, 500-507.
26. Liu, B.Q.; Gao, Y.Y.; Niu, X.F.; Xie, J.S.; Meng, X.; Guan, Y.; Wang, H.Q. Implication of unfolded protein response in resveratrol-induced inhibition of K562 cell proliferation. Biochem. Biophys. Res. Comm. 2010, 391, 778-782.
27. Fibach, E.; Prus, E.; Bianchi, N.; Zuccato, C.; Breveglieri, G.; Salvatori, F.; Finotti, A.; Lipucci di Paola, M.; Brognara, E.; Lampronti, I.; et al. Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β-thalassemia patients. Int. J. Mol. Med. 2012, 29, 974-982.
28. Lopez Hernandez, J.; Paseiro Losada, P.; Sanches-Silva, A.T.; Lage-Yusty, M.A. Study of the changes of trans-resveratrol caused by ultraviolet light and determination of trans-and cis-resveratrol in Spanish white wines. Eur. Food Res. Technol. 2007, 225, 789-796.
29. Chaovanalikit, A.; Wrolstad, R.E. Total antocyanins and total phenolics of fresh and processed cherries and their antioxidant properties. Food Chem. Toxicol. 2004, 69, 67-72.
30. Scartezzini, P.; Antognoni, F.; Poli F.; Sabbioni, C. Vitamin C content and antioxidant activity of the fruit and of the ayurvedic preparation of Emblica officinalis Gaertn. J. Ethnopharmacol. 2005, 104, 113-118.
31. Porter, L.J.; Hrstich, L.N.; Chan, B.C. The conversion of procyanidins and prodelphinidins to cyanidins and delphinidins. Phytochemistry 1986, 25, 225-330.
32. Bruni, R.; Rossi, D.; Muzzoli, M.; Romagnoli, C.; Paganetto, G.; Besco, E.; Choquecillo, F.; Peralta, K.; Lora, W.S.; Sacchetti, G. Antimutagenic, Antioxidant and antimicrobial properties of Maytenus krukovii bark. Fitoterapia 2006, 77, 538-545.
33. Luximon-Ramma, A.; Bahorun, T.; Soobrattee, M.A.; Aruoma, O.I. Antioxidant activities of phenolic, proanthocyanidin, and flavonoid components in extracts of Cassia fistula. J. Agric. Food Chem. 2002, 50, 5042-5047.
34. Bianchi, N.; Chiarabelli, C.; Borgatti, M.; Mischiati, C.; Fibach, E.; Gambari, R. Accumulation of γ-globin mRNA and induction erythroid differentiation after treatment of human leukaemic K562 cells with tallimustine. Br. J. Haematol. 2001, 113, 951-961.