-
1
-
-
84884002531
-
Physiology and molecular biology of the relaxin peptide family
-
In: (Secondary Bathgate RAD, Hsueh AJ, Sherwood OD) (Neill JD, ed. 3rd ed. San Diego: Elsevier
-
Bathgate RAD, Hsueh AJ, Sherwood OD 2006 Physiology and molecular biology of the relaxin peptide family. In: (Secondary Bathgate RAD, Hsueh AJ, Sherwood OD) (Neill JD, ed. Physiology of reproduction. 3rd ed. San Diego: Elsevier; 679-770
-
(2006)
Physiology of reproduction.
, pp. 679-770
-
-
Bathgate, R.A.D.1
Hsueh, A.J.2
Sherwood, O.D.3
-
2
-
-
33644589069
-
International Union of Pharmacology: Recommendations for the nomenclature of receptors for relaxin family peptides
-
Bathgate RA, Ivell R, Sanborn BM, Sherwood OD, Summers RJ 2006 International Union of Pharmacology: recommendations for the nomenclature of receptors for relaxin family peptides. Pharmacol Rev 58:7-31
-
(2006)
Pharmacol Rev
, vol.58
, pp. 7-31
-
-
Bathgate, R.A.1
Ivell, R.2
Sanborn, B.M.3
Sherwood, O.D.4
Summers, R.J.5
-
3
-
-
0000437998
-
Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seventransmembrane region
-
Hsu SY, Liang SG, Hsueh AJ 1998 Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seventransmembrane region. Mol Endocrinol 12:1830-1845
-
(1998)
Mol Endocrinol
, vol.12
, pp. 1830-1845
-
-
Hsu, S.Y.1
Liang, S.G.2
Hsueh, A.J.3
-
4
-
-
33845933437
-
Characterization of novel splice variants of LGR 7 and LGR 8 reveals that receptor signaling is mediated by their unique LDLa modules
-
Scott DJ, Layfield S, Yan Y, Sudo S, Hsueh AJ, Tregear GW, Bathgate RA 2006 Characterization of novel splice variants of LGR 7 and LGR 8 reveals that receptor signaling is mediated by their unique LDLa modules. J Biol Chem 281:34942-34954
-
(2006)
J Biol Chem
, vol.281
, pp. 34942-34954
-
-
Scott, D.J.1
Layfield, S.2
Yan, Y.3
Sudo, S.4
Hsueh, A.J.5
Tregear, G.W.6
Bathgate, R.A.7
-
5
-
-
33947501041
-
The NMR solution structure of the relaxin (RXFP 1) receptor lipoprotein receptor class A module and identification of key residues in the N-terminal region of the module that mediate receptor activation
-
Hopkins EJ, Layfield S, Ferraro T, Bathgate RA, Gooley PR 2007 The NMR solution structure of the relaxin (RXFP 1) receptor lipoprotein receptor class A module and identification of key residues in the N-terminal region of the module that mediate receptor activation. J Biol Chem 282:4172-4184
-
(2007)
J Biol Chem
, vol.282
, pp. 4172-4184
-
-
Hopkins, E.J.1
Layfield, S.2
Ferraro, T.3
Bathgate, R.A.4
Gooley, P.R.5
-
6
-
-
33847071711
-
The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): Its role in signaling and trafficking to the cell membrane
-
Kern A, Agoulnik AI, Bryant-Greenwood GD 2007 The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane. Endocrinology 148:1181-1194
-
(2007)
Endocrinology
, vol.148
, pp. 1181-1194
-
-
Kern, A.1
Agoulnik, A.I.2
Bryant-Greenwood, G.D.3
-
7
-
-
34347270603
-
Defining the LGR 8 residues involved in binding insulin-like peptide 3
-
Scott DJ, Wilkinson TN, Zhang S, Ferraro T, Wade JD, Tregear GW, Bathgate RA 2007 Defining the LGR 8 residues involved in binding insulin-like peptide 3. Mol Endocrinol 21:1699-1712
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1699-1712
-
-
Scott, D.J.1
Wilkinson, T.N.2
Zhang, S.3
Ferraro, T.4
Wade, J.D.5
Tregear, G.W.6
Bathgate, R.A.7
-
8
-
-
17144426920
-
The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7
-
Büllesbach EE, Schwabe C 2005 The trap-like relaxin-binding site of the leucine-rich G-protein-coupled receptor 7. J Biol Chem 280: 14051-14056
-
(2005)
J Biol Chem
, vol.280
, pp. 14051-14056
-
-
Büllesbach, E.E.1
Schwabe, C.2
-
9
-
-
0037169071
-
Activation of orphan receptors by the hormone relaxin
-
Hsu SY, Nakabayashi K, Nishi S, Kumagai J, Kudo M, Sherwood OD, Hsueh AJ 2002 Activation of orphan receptors by the hormone relaxin. Science 295:671-674
-
(2002)
Science
, vol.295
, pp. 671-674
-
-
Hsu, S.Y.1
Nakabayashi, K.2
Nishi, S.3
Kumagai, J.4
Kudo, M.5
Sherwood, O.D.6
Hsueh, A.J.7
-
10
-
-
0037424265
-
H 3 relaxin is a specific ligand for LGR 7 and activates the receptor by interacting with both the ectodomain and the exoloop 2
-
Sudo S, Kumagai J, Nishi S, Layfield S, Ferraro T, Bathgate RA, Hsueh AJ 2003 H 3 relaxin is a specific ligand for LGR 7 and activates the receptor by interacting with both the ectodomain and the exoloop 2. J Biol Chem 278:7855-7862
-
(2003)
J Biol Chem
, vol.278
, pp. 7855-7862
-
-
Sudo, S.1
Kumagai, J.2
Nishi, S.3
Layfield, S.4
Ferraro, T.5
Bathgate, R.A.6
Hsueh, A.J.7
-
11
-
-
18044378198
-
Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR 7 and LGR 8)
-
Halls ML, Bond CP, Sudo S, Kumagai J, Ferraro T, Layfield S, Bathgate RA, Summers RJ 2005 Multiple binding sites revealed by interaction of relaxin family peptides with native and chimeric relaxin family peptide receptors 1 and 2 (LGR 7 and LGR 8). J Pharmacol Exp Ther 313:677-687
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 677-687
-
-
Halls, M.L.1
Bond, C.P.2
Sudo, S.3
Kumagai, J.4
Ferraro, T.5
Layfield, S.6
Bathgate, R.A.7
Summers, R.J.8
-
12
-
-
64549155679
-
Resolving the unconventional mechanisms underlying RXFP 1 and RXFP 2 receptor function
-
Hartley BJ, Scott DJ, Callander GE, Wilkinson TN, Ganella DE, Kong CK, Layfield S, Ferraro T, Petrie EJ, Bathgate RAD 2009 Resolving the unconventional mechanisms underlying RXFP 1 and RXFP 2 receptor function. Ann NY Acad Sci 1160:67-73
-
(2009)
Ann NY Acad Sci
, vol.1160
, pp. 67-73
-
-
Hartley, B.J.1
Scott, D.J.2
Callander, G.E.3
Wilkinson, T.N.4
Ganella, D.E.5
Kong, C.K.6
Layfield, S.7
Ferraro, T.8
Petrie, E.J.9
Bathgate, R.A.D.10
-
14
-
-
33748762210
-
Solution structure and characterization of the receptor binding surface of insulin-like peptide 3
-
Rosengren KJ, Zhang S, Lin F, Daly NL, Scott DJ, Hughes RA, Bathgate RA, Craik DJ, Wade JD 2006 Solution structure and characterization of the receptor binding surface of insulin-like peptide 3. J Biol Chem 281:28287-28295
-
(2006)
J Biol Chem
, vol.281
, pp. 28287-28295
-
-
Rosengren, K.J.1
Zhang, S.2
Lin, F.3
Daly, N.L.4
Scott, D.J.5
Hughes, R.A.6
Bathgate, R.A.7
Craik, D.J.8
Wade, J.D.9
-
15
-
-
47749156401
-
Solid-phase synthesis of europium-labeled human INSL 3 as a novel probe for the study of ligand-receptor interactions
-
Shabanpoor F, Hughes RA, Bathgate RA, Zhang S, Scanlon DB, Lin F, Hossain MA, Separovic F, Wade JD 2008 Solid-phase synthesis of europium-labeled human INSL 3 as a novel probe for the study of ligand-receptor interactions. Bioconjug Chem 19:1456-1463
-
(2008)
Bioconjug Chem
, vol.19
, pp. 1456-1463
-
-
Shabanpoor, F.1
Hughes, R.A.2
Bathgate, R.A.3
Zhang, S.4
Scanlon, D.B.5
Lin, F.6
Hossain, M.A.7
Separovic, F.8
Wade, J.D.9
-
16
-
-
3843146246
-
An efficient one-step site-directed and site-saturation mutagenesis protocol
-
Zheng L, Baumann U, Reymond JL 2004 An efficient one-step site-directed and site-saturation mutagenesis protocol. Nucleic Acids Res 32:e115
-
(2004)
Nucleic Acids Res
, vol.32
-
-
Zheng, L.1
Baumann, U.2
Reymond, J.L.3
-
17
-
-
64149101159
-
Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL 7) that exhibit full biological activity
-
Hossain MA, Rosengren KJ, Zhang S, Bathgate RA, Tregear GW, van Lierop BJ, Robinson AJ, Wade JD 2009 Solid phase synthesis and structural analysis of novel A-chain dicarba analogs of human relaxin-3 (INSL 7) that exhibit full biological activity. Org Biomol Chem 7:1547-1553
-
(2009)
Org Biomol Chem
, vol.7
, pp. 1547-1553
-
-
Hossain, M.A.1
Rosengren, K.J.2
Zhang, S.3
Bathgate, R.A.4
Tregear, G.W.5
van Lierop, B.J.6
Robinson, A.J.7
Wade, J.D.8
-
18
-
-
46049108362
-
Identification of the N-linked glycosylation sites of the human relaxin receptor and effect of glycosylation on receptor function
-
Yan Y, Scott DJ, Wilkinson TN, Ji J, Tregear GW, Bathgate RA 2008 Identification of the N-linked glycosylation sites of the human relaxin receptor and effect of glycosylation on receptor function. Biochemistry 47:6953-6968
-
(2008)
Biochemistry
, vol.47
, pp. 6953-6968
-
-
Yan, Y.1
Scott, D.J.2
Wilkinson, T.N.3
Ji, J.4
Tregear, G.W.5
Bathgate, R.A.6
-
19
-
-
0028947365
-
A colorimetric assay for measuring activation of Gs-and Gq-coupled signaling pathways
-
Chen W, Shields TS, Stork PJ, Cone RD 1995 A colorimetric assay for measuring activation of Gs-and Gq-coupled signaling pathways. Anal Biochem 226:349-354
-
(1995)
Anal Biochem
, vol.226
, pp. 349-354
-
-
Chen, W.1
Shields, T.S.2
Stork, P.J.3
Cone, R.D.4
-
20
-
-
0037442962
-
HADDOCK: A protein-protein docking approach based on biochemical or biophysical information
-
Dominguez C, Boelens R, Bonvin AM 2003 HADDOCK: a protein-protein docking approach based on biochemical or biophysical information. J Am Chem Soc 125:1731-1737
-
(2003)
J Am Chem Soc
, vol.125
, pp. 1731-1737
-
-
Dominguez, C.1
Boelens, R.2
Bonvin, A.M.3
-
21
-
-
33748746259
-
The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G proteinactivated receptor 8
-
Büllesbach EE, Schwabe C 2006 The mode of interaction of the relaxin-like factor (RLF) with the leucine-rich repeat G proteinactivated receptor 8. J Biol Chem 281:26136-26143
-
(2006)
J Biol Chem
, vol.281
, pp. 26136-26143
-
-
Büllesbach, E.E.1
Schwabe, C.2
-
22
-
-
0038325765
-
Structure of the Nogo receptor ectodomain: A recognition module implicated in myelin inhibition
-
He XL, Bazan JF, McDermott G, Park JB, Wang K, Tessier-Lavigne M, He Z, Garcia KC 2003 Structure of the Nogo receptor ectodomain: a recognition module implicated in myelin inhibition. Neuron 38:177-185
-
(2003)
Neuron
, vol.38
, pp. 177-185
-
-
He, X.L.1
Bazan, J.F.2
McDermott, G.3
Park, J.B.4
Wang, K.5
Tessier-Lavigne, M.6
He, Z.7
Garcia, K.C.8
-
23
-
-
17644415042
-
LGR 8 signal activation by the relaxin-like factor
-
Büllesbach EE, Schwabe C 2005 LGR 8 signal activation by the relaxin-like factor. J Biol Chem 280:14586-14590
-
(2005)
J Biol Chem
, vol.280
, pp. 14586-14590
-
-
Büllesbach, E.E.1
Schwabe, C.2
-
24
-
-
47749116027
-
The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors
-
Hossain MA, Rosengren KJ, Haugaard-Jönsson LM, Zhang S, Layfield S, Ferraro T, Daly NL, Tregear GW, Wade JD, Bathgate RA 2008 The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors. J Biol Chem 283:17287-17297
-
(2008)
J Biol Chem
, vol.283
, pp. 17287-17297
-
-
Hossain, M.A.1
Rosengren, K.J.2
Haugaard-Jönsson, L.M.3
Zhang, S.4
Layfield, S.5
Ferraro, T.6
Daly, N.L.7
Tregear, G.W.8
Wade, J.D.9
Bathgate, R.A.10
-
25
-
-
33744955536
-
Analogs of insulin-like peptide 3 (INSL 3) B-chain are LGR 8 antagonists in vitro and in vivo
-
Del Borgo MP, Hughes RA, Bathgate RA, Lin F, Kawamura K, Wade JD 2006 Analogs of insulin-like peptide 3 (INSL 3) B-chain are LGR 8 antagonists in vitro and in vivo. J Biol Chem 281:13068-13074
-
(2006)
J Biol Chem
, vol.281
, pp. 13068-13074
-
-
Del Borgo, M.P.1
Hughes, R.A.2
Bathgate, R.A.3
Lin, F.4
Kawamura, K.5
Wade, J.D.6
-
26
-
-
33847136099
-
Design, synthesis and pharmacological evaluation of cyclic mimetics of the insulin-like peptide 3 (INSL 3) B-chain
-
Shabanpoor F, Bathgate RA, Hossain MA, Giannakis E, Wade JD, Hughes RA 2007 Design, synthesis and pharmacological evaluation of cyclic mimetics of the insulin-like peptide 3 (INSL 3) B-chain. J Pept Sci 13:113-120
-
(2007)
J Pept Sci
, vol.13
, pp. 113-120
-
-
Shabanpoor, F.1
Bathgate, R.A.2
Hossain, M.A.3
Giannakis, E.4
Wade, J.D.5
Hughes, R.A.6
-
27
-
-
79959805619
-
Design and development of analogues of dimers of insulin-like peptide 3 Bchain as high-affinity antagonists of the RXFP 2 receptor
-
Shabanpoor F, Zhang S, Hughes RA, Hossain MA, Layfield S, Ferraro T, Bathgate RA, Separovic F, Wade JD 2011 Design and development of analogues of dimers of insulin-like peptide 3 Bchain as high-affinity antagonists of the RXFP 2 receptor. Biopolymers 96:81-87
-
(2011)
Biopolymers
, vol.96
, pp. 81-87
-
-
Shabanpoor, F.1
Zhang, S.2
Hughes, R.A.3
Hossain, M.A.4
Layfield, S.5
Ferraro, T.6
Bathgate, R.A.7
Separovic, F.8
Wade, J.D.9
-
28
-
-
12744280744
-
Structure of human follicle-stimulating hormone in complex with its receptor
-
Fan QR, Hendrickson WA 2005 Structure of human follicle-stimulating hormone in complex with its receptor. Nature 433:269-277
-
(2005)
Nature
, vol.433
, pp. 269-277
-
-
Fan, Q.R.1
Hendrickson, W.A.2
-
29
-
-
84864502784
-
Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor
-
13491-12496
-
Jiang X, Liu H, Chen X, Chen PH, Fischer D, Sriraman V, Yu HN, Arkinstall S, He X 2012 Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor. Proc Natl Acad Sci USA 109:13491-12496
-
(2012)
Proc Natl Acad Sci USA
, vol.109
-
-
Jiang, X.1
Liu, H.2
Chen, X.3
Chen, P.H.4
Fischer, D.5
Sriraman, V.6
Yu, H.N.7
Arkinstall, S.8
He, X.9
|