Lack of evidence for reduced fitness of clinical staphylococcus aureus isolates with reduced susceptibility to Triclosan

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 11, 2012, Pages 6068-6069

  Oggioni, Marco Rinaldo ^a   Ciusa, Maria Laura ^a   Furi, Leonardo ^a   Baldassarri, Lucilla ^b   Orefici, Graziella ^b   Cirasola, Daniela ^c   Martinez, Jose Luis ^d   Morrissey, Ian ^e   Borghi, Elisa ^c  

^a UNIVERSITY OF SIENA   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^e Quotient Bioresearch Ltd   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TRICLOSAN;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; GALLERIA MELLONELLA; LETTER; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BIOFILMS; STAPHYLOCOCCUS AUREUS; TRICLOSAN;

EID: 84868021559     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01055-12     Document Type: Letter

References (5)

1. Bayston R, Ashraf W, Smith T. 2007. Triclosan resistance in meticillinresistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics. J. Antimicrob. Chemother. 59:848-853.
2. Ciusa ML, et al. 2012. A novel resistance mechanism to triclosan that suggests horizontal gene transfer and demonstrates a potential selective pressure for reduced biocide susceptibility in clinical strains of Staphylococcus aureus. Int. J. Antimicrob. Agents 40:210-220.
3. Latimer J, Forbes S, McBain AJ. 2012. Attenuated virulence and biofilm formation in Staphylococcus aureus following sublethal exposure to triclosan. Antimicrob. Agents Chemother. 56:3092-3100.
4. Seaman PF, Ochs D, Day MJ. 2007. Small-colony variants: a novel mechanism for triclosan resistance in methicillin-resistant Staphylococcus aureus. J. Antimicrob. Chemother. 59:43-50.
5. Suller MT, Russell AD. 2000. Triclosan and antibiotic resistance in Staphylococcus aureus. J. Antimicrob. Chemother. 46:11-18.