메뉴 건너뛰기




Volumn 27, Issue 11, 2012, Pages 2039-2048

Phosphate homeostasis and its role in bone health

Author keywords

Chondrocytes; FGF 23; Growth plate; Parathyroid hormone; Phosphate; Vitamin D

Indexed keywords


EID: 84868019347     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-012-2175-z     Document Type: Review
Times cited : (321)

References (50)
  • 1
    • 77955362086 scopus 로고    scopus 로고
    • Phosphate homeostasis and the renal-gastrointestinal axis
    • 20534868 10.1152/ajprenal.00508.2009 1:CAS:528:DC%2BC3cXhtVOgsr%2FN
    • Marks J, Edward S, Debnam ES, Unwi RJ (2010) Phosphate homeostasis and the renal-gastrointestinal axis. Am J Physiol Renal Physiol 299:F285-F296
    • (2010) Am J Physiol Renal Physiol , vol.299
    • Marks, J.1    Edward, S.2    Debnam, E.S.3    Unwi, R.J.4
  • 2
    • 34547443884 scopus 로고    scopus 로고
    • Evidence for a signaling axis by which intestinal phosphate rapidly modulates renal phosphate reabsorption
    • 17566100 10.1073/pnas.0704446104 1:CAS:528:DC%2BD2sXnsVymsbo%3D
    • Berndt T, Thomas LF, Craig TA, Sommer S, Li X, Bergstralh EJ, Kumar R (2007) Evidence for a signaling axis by which intestinal phosphate rapidly modulates renal phosphate reabsorption. Proc Natl Acad Sci USA 104:11085-11090
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 11085-11090
    • Berndt, T.1    Thomas, L.F.2    Craig, T.A.3    Sommer, S.4    Li, X.5    Bergstralh, E.J.6    Kumar, R.7
  • 3
    • 46949085020 scopus 로고    scopus 로고
    • Regulation of phosphate homeostasis by the phosphatonins and other novel mediators
    • 18288501 10.1007/s00467-008-0751-z
    • Shaikh A, Berndt T, Kumar R (2008) Regulation of phosphate homeostasis by the phosphatonins and other novel mediators. Pediatr Nephrol 23:1203-1210
    • (2008) Pediatr Nephrol , vol.23 , pp. 1203-1210
    • Shaikh, A.1    Berndt, T.2    Kumar, R.3
  • 5
    • 77952892243 scopus 로고    scopus 로고
    • Expression of renal and intestinal Na/Pi cotransporters in the absence of GABARAP
    • 10.1007/s00424-010-0832-2
    • Reining SC, Liesegang A, Betz H, Biber J, Murer H, Hernando N (2010) Expression of renal and intestinal Na/Pi cotransporters in the absence of GABARAP. Pflügers Arch 460:201-217
    • (2010) Pflügers Arch , vol.460 , pp. 201-217
    • Reining, S.C.1    Liesegang, A.2    Betz, H.3    Biber, J.4    Murer, H.5    Hernando, N.6
  • 6
    • 73949096454 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and its role in phosphate homeostasis
    • 19776202 10.1530/EJE-09-0597 1:CAS:528:DC%2BC3cXntFOqsA%3D%3D
    • Ramon I, Kleynen P, Jean-Jacques Body J, Karmali R (2010) Fibroblast growth factor 23 and its role in phosphate homeostasis. Eur J Endocrinol 162:1-10
    • (2010) Eur J Endocrinol , vol.162 , pp. 1-10
    • Ramon, I.1    Kleynen, P.2    Jean-Jacques Body, J.3    Karmali, R.4
  • 7
    • 77951259224 scopus 로고    scopus 로고
    • Regulation of phosphate transport by fibroblast growth factor 23 (FGF-23): Implications for disorders of phosphate metabolism
    • 19669798 10.1007/s00467-009-1273-z
    • Gattineni J, Baum M (2010) Regulation of phosphate transport by fibroblast growth factor 23 (FGF-23): implications for disorders of phosphate metabolism. Pediatr Nephrol 25:591-601
    • (2010) Pediatr Nephrol , vol.25 , pp. 591-601
    • Gattineni, J.1    Baum, M.2
  • 8
    • 33644818657 scopus 로고    scopus 로고
    • Hypophosphatemia: An evidence-based approach to its clinical consequences and management
    • 16932412 10.1038/ncpneph0124 1:CAS:528:DC%2BD28XivFCltLc%3D
    • Amanzadeh J, Reilly RF Jr (2006) Hypophosphatemia: an evidence-based approach to its clinical consequences and management. Nat Clin Pract Nephrol 2:136-148
    • (2006) Nat Clin Pract Nephrol , vol.2 , pp. 136-148
    • Amanzadeh, J.1    Reilly, Jr.R.F.2
  • 9
    • 67749113165 scopus 로고    scopus 로고
    • Hypophosphatemia: The common denominator of all rickets
    • 19504043 10.1007/s00774-009-0079-1
    • Tiosano D, Hochberg Z (2009) Hypophosphatemia: the common denominator of all rickets. J Bone Miner Metab 27:392-401
    • (2009) J Bone Miner Metab , vol.27 , pp. 392-401
    • Tiosano, D.1    Hochberg, Z.2
  • 10
    • 27944491618 scopus 로고    scopus 로고
    • Phosphatonins and the regulation of phosphorus homeostasis
    • 16275744 10.1152/ajprenal.00072.2005 1:CAS:528:DC%2BD28XlslKhtQ%3D%3D
    • Berndt TJ, Schiavi S, Kumar R (2005) Phosphatonins and the regulation of phosphorus homeostasis. Am J Physiol Renal Physiol 289:F1170-F1182
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Berndt, T.J.1    Schiavi, S.2    Kumar, R.3
  • 11
    • 78049369446 scopus 로고    scopus 로고
    • Hereditary disorders of renal phosphate wasting
    • 20924400 10.1038/nrneph.2010.121 1:CAS:528:DC%2BC3cXhtlCjsL%2FM
    • Alizadeh Naderi AS, Reilly RF (2010) Hereditary disorders of renal phosphate wasting. Nat Rev Nephrol 6:657-665
    • (2010) Nat Rev Nephrol , vol.6 , pp. 657-665
    • Alizadeh Naderi, A.S.1    Reilly, R.F.2
  • 12
    • 77950297228 scopus 로고    scopus 로고
    • Recent advances in renal phosphate handling
    • 20177401 10.1038/nrneph.2010.17
    • Farrow EG, White KE (2010) Recent advances in renal phosphate handling. Nat Rev Nephrol 6:207-217
    • (2010) Nat Rev Nephrol , vol.6 , pp. 207-217
    • Farrow, E.G.1    White, K.E.2
  • 13
    • 77951920659 scopus 로고    scopus 로고
    • Regulation of phosphate homeostasis by PTH, vitamin D and FGF-23
    • 20059333 10.1146/annurev.med.051308.111339 1:CAS:528:DC%2BC3cXisFylsL4%3D
    • Bergwitz C, Huppner H (2010) Regulation of phosphate homeostasis by PTH, vitamin D and FGF-23. Annu Rev Med 61:91-104
    • (2010) Annu Rev Med , vol.61 , pp. 91-104
    • Bergwitz, C.1    Huppner, H.2
  • 14
    • 79955597653 scopus 로고    scopus 로고
    • Clinical practice: Fibroblast growth factor (FGF)23: A new hormone
    • 21193927 10.1007/s00431-010-1382-5 1:CAS:528:DC%2BC3MXovFChtLg%3D
    • Alon US (2011) Clinical practice: Fibroblast growth factor (FGF)23: a new hormone. Eur J Pediatr 170:545-554
    • (2011) Eur J Pediatr , vol.170 , pp. 545-554
    • Alon, U.S.1
  • 15
    • 0036084055 scopus 로고    scopus 로고
    • Age-dependent regulation of rat intestinal type IIb sodium-phosphate cotransporter by 1,25-(OH)2 vitamin D3
    • 11832333 1:CAS:528:DC%2BD38Xit1GitLk%3D
    • Xu H, Bai L, Collins JF, Ghishan FK (2002) Age-dependent regulation of rat intestinal type IIb sodium-phosphate cotransporter by 1,25-(OH)2 vitamin D3. Am J Physiol Cell Physiol 282:C487-C493
    • (2002) Am J Physiol Cell Physiol , vol.282
    • Xu, H.1    Bai, L.2    Collins, J.F.3    Ghishan, F.K.4
  • 16
    • 23944521772 scopus 로고    scopus 로고
    • Regulation of phosphorus homeostasis by the type IIa Na/phosphate cotransporter
    • 16011465 10.1146/annurev.nutr.25.050304.092642 1:CAS:528: DC%2BD2MXpvF2mtr0%3D
    • Tenenhouse HS (2005) Regulation of phosphorus homeostasis by the type IIa Na/phosphate cotransporter. Annu Rev Nutr 25:197-214
    • (2005) Annu Rev Nutr , vol.25 , pp. 197-214
    • Tenenhouse, H.S.1
  • 17
    • 77951253593 scopus 로고    scopus 로고
    • FGF-23 in bone biology
    • 20012997 10.1007/s00467-009-1384-6
    • Wesseling-Perry K (2010) FGF-23 in bone biology. Pediatr Nephrol 25:603-608
    • (2010) Pediatr Nephrol , vol.25 , pp. 603-608
    • Wesseling-Perry, K.1
  • 18
    • 0034999861 scopus 로고    scopus 로고
    • Regulation of the human sodium-phosphate cotransporter NaPi-IIb gene promoter by epidermal growth factor
    • 11171583 1:CAS:528:DC%2BD3MXjtVWrurc%3D
    • Xu H, Collins JF, Bai L, Kiela PR, Ghishan FK (2001) Regulation of the human sodium-phosphate cotransporter NaPi-IIb gene promoter by epidermal growth factor. Am J Physiol Cell Physiol 280:C628-C636
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Xu, H.1    Collins, J.F.2    Bai, L.3    Kiela, P.R.4    Ghishan, F.K.5
  • 21
    • 13844322105 scopus 로고    scopus 로고
    • Regulation of intestinal phosphate transport. II. Metabolic acidosis stimulates Na+-dependent phosphate absorption and expression of the Na+-Pi cotransporter NaPi-IIb in small intestine
    • 15701624 10.1152/ajpgi.00168.2004 1:CAS:528:DC%2BD2MXisVKqsbk%3D
    • Stauber A, Radanovic T, Stange G, Murer H, Wagner CA, Biber J (2005) Regulation of intestinal phosphate transport. II. Metabolic acidosis stimulates Na+-dependent phosphate absorption and expression of the Na+-Pi cotransporter NaPi-IIb in small intestine. Am J Physiol Gastrointest Liver Physiol 288:G501-G506
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.288
    • Stauber, A.1    Radanovic, T.2    Stange, G.3    Murer, H.4    Wagner, C.A.5    Biber, J.6
  • 22
    • 1242317643 scopus 로고    scopus 로고
    • The sodium phosphate cotransporter family SLC34
    • 12750889 10.1007/s00424-003-1072-5 1:CAS:528:DC%2BD2cXhtVygsLg%3D
    • Murer H, Forster I, Biber J (2004) The sodium phosphate cotransporter family SLC34. Pflügers Arch 447:763-767
    • (2004) Pflügers Arch , vol.447 , pp. 763-767
    • Murer, H.1    Forster, I.2    Biber, J.3
  • 23
    • 2942635904 scopus 로고    scopus 로고
    • Intestinal Na-P(i) cotransporter adaptation to dietary P(i) content in vitamin D receptor null mice
    • 14996670 10.1152/ajprenal.00375.2003 1:CAS:528:DC%2BD2cXmtVektr0%3D
    • Segawa H, Kaneko I, Yamanaka S, Ito M, Kuwahata M, Inoue Y, Kato S, Miyamoto K (2004) Intestinal Na-P(i) cotransporter adaptation to dietary P(i) content in vitamin D receptor null mice. Am J Physiol Renal Physiol 287:F39-F47
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Segawa, H.1    Kaneko, I.2    Yamanaka, S.3    Ito, M.4    Kuwahata, M.5    Inoue, Y.6    Kato, S.7    Miyamoto, K.8
  • 24
    • 12144274056 scopus 로고    scopus 로고
    • Intestinal and renal adaptation to a low-Pi diet of type II NaPi cotransporters in vitamin D receptor- and 1 OHase-deficient mice
    • 15643054 10.1152/ajpcell.00331.2004 1:CAS:528:DC%2BD2MXhsVCksbs%3D
    • Capuano P, Radanovic T, Wagner CA, Bacic D, Kato S, Uchiyama Y, St Arnoud R, Murer H, Biber J (2005) Intestinal and renal adaptation to a low-Pi diet of type II NaPi cotransporters in vitamin D receptor- and 1 OHase-deficient mice. Am J Physiol Cell Physiol 288:C429-C434
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Capuano, P.1    Radanovic, T.2    Wagner, C.A.3    Bacic, D.4    Kato, S.5    Uchiyama, Y.6    St Arnoud, R.7    Murer, H.8    Biber, J.9
  • 25
    • 2142818149 scopus 로고    scopus 로고
    • Phosphate is a specific signal for ATDC5 chondrocyte maturation and apoptosis-associated mineralization: Possible implication of apoptosis in the regulation of endochondral ossification
    • 12929932 10.1359/jbmr.2003.18.8.1430 1:CAS:528:DC%2BD3sXmslSgu7c%3D
    • Magne D, Bluteau G, Faucheux C, Palmer G, Vignes-Colombeix C, Pilet P, Rouillon T, Caverzasio J, Weiss P, Daculsi G, Guicheux J (2003) Phosphate is a specific signal for ATDC5 chondrocyte maturation and apoptosis-associated mineralization: possible implication of apoptosis in the regulation of endochondral ossification. J Bone Miner Res 18:1430-1442
    • (2003) J Bone Miner Res , vol.18 , pp. 1430-1442
    • Magne, D.1    Bluteau, G.2    Faucheux, C.3    Palmer, G.4    Vignes-Colombeix, C.5    Pilet, P.6    Rouillon, T.7    Caverzasio, J.8    Weiss, P.9    Daculsi, G.10    Guicheux, J.11
  • 26
    • 33747719260 scopus 로고    scopus 로고
    • Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men
    • 16735491 10.1210/jc.2006-0021 1:CAS:528:DC%2BD28XosFGht78%3D
    • Antoniucci DM, Yamashita T, Portale AA (2006) Dietary phosphorus regulates serum fibroblast growth factor-23 concentrations in healthy men. J Clin Endocrinol Metab 91:3144-3149
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 3144-3149
    • Antoniucci, D.M.1    Yamashita, T.2    Portale, A.A.3
  • 27
    • 31544469808 scopus 로고    scopus 로고
    • The renal Na+/phosphate cotransporter NaPi-IIa is internalized via the receptor-mediated endocytic route in response to parathyroid hormone
    • 16514432 10.1038/sj.ki.5000148 1:CAS:528:DC%2BD28XnsV2rug%3D%3D
    • Bacic D, Lehir M, Biber J, Kaissling B, Murer H, Wagner CA (2006) The renal Na+/phosphate cotransporter NaPi-IIa is internalized via the receptor-mediated endocytic route in response to parathyroid hormone. Kidney Int 69:495-503
    • (2006) Kidney Int , vol.69 , pp. 495-503
    • Bacic, D.1    Lehir, M.2    Biber, J.3    Kaissling, B.4    Murer, H.5    Wagner, C.A.6
  • 28
    • 65949096839 scopus 로고    scopus 로고
    • The Na+-Pi cotransporter PiT-2 (SLC20A2) is expressed in the apical membrane of rat renal proximal tubules and regulated by dietary Pi
    • 19073637 10.1152/ajprenal.90623.2008 1:CAS:528:DC%2BD1MXkvVyns7c%3D
    • Villa-Bellosta R, Ravera S, Sorribas V, Stange G, Levi M, Murer H, Biber J, Forster IC (2009) The Na+-Pi cotransporter PiT-2 (SLC20A2) is expressed in the apical membrane of rat renal proximal tubules and regulated by dietary Pi. Am J Physiol Renal Physiol 296:F691-F699
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Villa-Bellosta, R.1    Ravera, S.2    Sorribas, V.3    Stange, G.4    Levi, M.5    Murer, H.6    Biber, J.7    Forster, I.C.8
  • 29
    • 64549093430 scopus 로고    scopus 로고
    • Regulation of phosphate transport in proximal tubules
    • 18758808 10.1007/s00424-008-0580-8 1:CAS:528:DC%2BD1MXktVGksL4%3D
    • Biber J, Hernando N, Forster I, Murer H (2009) Regulation of phosphate transport in proximal tubules. Pflügers Arch 458:39-52
    • (2009) Pflügers Arch , vol.458 , pp. 39-52
    • Biber, J.1    Hernando, N.2    Forster, I.3    Murer, H.4
  • 31
    • 64949097327 scopus 로고    scopus 로고
    • Latest findings in phosphate homeostasis
    • 19190675 10.1038/ki.2008.643 1:CAS:528:DC%2BD1MXks1Sjt74%3D
    • Prie D, Urena TP, Friedlander G (2009) Latest findings in phosphate homeostasis. Kidney Int 75:882-889
    • (2009) Kidney Int , vol.75 , pp. 882-889
    • Prie, D.1    Urena, T.P.2    Friedlander, G.3
  • 32
    • 14044250225 scopus 로고    scopus 로고
    • Internalization of renal type IIc Na-Pi cotransporter in response to a high-phosphate diet
    • 15561978 10.1152/ajprenal.00097.2004 1:CAS:528:DC%2BD2MXisVOjurs%3D
    • Segawa H, Yamanaka S, Ito M, Kuwahata M, Shono M, Yamamoto T, Miyamoto K (2005) Internalization of renal type IIc Na-Pi cotransporter in response to a high-phosphate diet. Am J Physiol Renal Physiol 288:F587-F596
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Segawa, H.1    Yamanaka, S.2    Ito, M.3    Kuwahata, M.4    Shono, M.5    Yamamoto, T.6    Miyamoto, K.7
  • 35
    • 77949885535 scopus 로고    scopus 로고
    • Compensatory regulation of the sodium/phosphate cotransporters NaPi-IIc (SCL34A3) and Pit-2 (SLC20A2) during Pi deprivation and acidosis
    • 19841935 10.1007/s00424-009-0746-z 1:CAS:528:DC%2BC3cXps1WqtQ%3D%3D
    • Villa-Bellosta R, Sorribas V (2010) Compensatory regulation of the sodium/phosphate cotransporters NaPi-IIc (SCL34A3) and Pit-2 (SLC20A2) during Pi deprivation and acidosis. Pflügers Arch 459:499-508
    • (2010) Pflügers Arch , vol.459 , pp. 499-508
    • Villa-Bellosta, R.1    Sorribas, V.2
  • 36
    • 77957260363 scopus 로고    scopus 로고
    • FGF-23 and the parathyroid glands
    • 20526631 10.1007/s00467-010-1565-3
    • Silver J, Naveh-Many T (2010) FGF-23 and the parathyroid glands. Pediatr Nephrol 25:2241-2245
    • (2010) Pediatr Nephrol , vol.25 , pp. 2241-2245
    • Silver, J.1    Naveh-Many, T.2
  • 37
    • 77951255990 scopus 로고    scopus 로고
    • Overview of the FGF-23 -Klotho axis
    • 19626341 10.1007/s00467-009-1260-4
    • Kuro-o M (2010) Overview of the FGF-23 -Klotho axis. Pediatr Nephrol 25:583-590
    • (2010) Pediatr Nephrol , vol.25 , pp. 583-590
    • Kuro-O, M.1
  • 39
    • 28444486604 scopus 로고    scopus 로고
    • 1 α,25-Dihydroxyvitamin D3 upregulates FGF-23 gene expression in bone: The final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport
    • 16020653 10.1152/ajpgi.00243.2005 1:CAS:528:DC%2BD28XlslOjtw%3D%3D
    • Kolek OI, Hines ER, Jones MD, LeSueur LK, Lipko MA, Kiela PR, Collins JF, Haussler MR, Ghishan FK (2005) 1 α,25-Dihydroxyvitamin D3 upregulates FGF-23 gene expression in bone: the final link in a renal-gastrointestinal- skeletal axis that controls phosphate transport. Am J Physiol Gastrointest Liver Physiol 289:G1036-G1042
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289
    • Kolek, O.I.1    Hines, E.R.2    Jones, M.D.3    Lesueur, L.K.4    Lipko, M.A.5    Kiela, P.R.6    Collins, J.F.7    Haussler, M.R.8    Ghishan, F.K.9
  • 41
  • 44
    • 44449118964 scopus 로고    scopus 로고
    • Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro
    • 18282132 10.1359/jbmr.080220 1:CAS:528:DC%2BD1cXnvVGjsL4%3D
    • Wang H, Yoshiko Y, Yamamoto R, Minamizaki T, Kozai K, Tanne K, Aubin JE, Maeda N (2008) Overexpression of fibroblast growth factor 23 suppresses osteoblast differentiation and matrix mineralization in vitro. J Bone Miner Res 23:939-948
    • (2008) J Bone Miner Res , vol.23 , pp. 939-948
    • Wang, H.1    Yoshiko, Y.2    Yamamoto, R.3    Minamizaki, T.4    Kozai, K.5    Tanne, K.6    Aubin, J.E.7    Maeda, N.8
  • 45
    • 0025726307 scopus 로고
    • Rearrangement of the metaphyseal vasculature of the rat growth plate in rickets and rachitic reversal: A model of vascular arrest and angiogenesis renewed
    • 1710878 10.1002/ar.1092290404 1:STN:280:DyaK3M3msVamsg%3D%3D
    • Hunter WL, Arsenault AL, Hodsman AB (1991) Rearrangement of the metaphyseal vasculature of the rat growth plate in rickets and rachitic reversal: a model of vascular arrest and angiogenesis renewed. Anat Rec 229:453-461
    • (1991) Anat Rec , vol.229 , pp. 453-461
    • Hunter, W.L.1    Arsenault, A.L.2    Hodsman, A.B.3
  • 46
    • 0036212302 scopus 로고    scopus 로고
    • Extracellular Ca(2+)-sensing receptors modulate matrix production and mineralization in chondrogenic RCJ3.1C5.18 cells
    • 11897705 10.1210/en.143.4.1467 1:CAS:528:DC%2BD38XisFGisbo%3D
    • Chang W, Tu C, Pratt S, Chen TH, Shoback D (2002) Extracellular Ca(2+)-sensing receptors modulate matrix production and mineralization in chondrogenic RCJ3.1C5.18 cells. Endocrinology 143:1467-1474
    • (2002) Endocrinology , vol.143 , pp. 1467-1474
    • Chang, W.1    Tu, C.2    Pratt, S.3    Chen, T.H.4    Shoback, D.5
  • 47
    • 22144495738 scopus 로고    scopus 로고
    • Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes
    • 15976027 10.1073/pnas.0502249102 1:CAS:528:DC%2BD2MXmsVaktLs%3D
    • Sabbagh Y, Carpenter TO, Demay MB (2005) Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes. Proc Natl Acad Sci USA 102:9637-9642
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 9637-9642
    • Sabbagh, Y.1    Carpenter, T.O.2    Demay, M.B.3
  • 48
    • 0000524953 scopus 로고    scopus 로고
    • Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice
    • 9751523 10.1210/en.139.10.4391 1:CAS:528:DyaK1cXmsVGms7Y%3D
    • Li YC, Amling M, Pirro AE, Priemel M, Meuse J, Baron R, Delling G, Demay MB (1998) Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice. Endocrinology 139:4391-4396
    • (1998) Endocrinology , vol.139 , pp. 4391-4396
    • Li, Y.C.1    Amling, M.2    Pirro, A.E.3    Priemel, M.4    Meuse, J.5    Baron, R.6    Delling, G.7    Demay, M.B.8
  • 50
    • 77953317000 scopus 로고    scopus 로고
    • Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation
    • 20404333 10.1074/jbc.M109.098616 1:CAS:528:DC%2BC3cXmvFarurY%3D
    • Miedlich SU, Zalutskaya A, Zhu ED, Demay MB (2010) Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation. J Biol Chem 285:18270-18275
    • (2010) J Biol Chem , vol.285 , pp. 18270-18275
    • Miedlich, S.U.1    Zalutskaya, A.2    Zhu, E.D.3    Demay, M.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.