Neoangiogenesis is reduced in chronic tendinopathies of type 2 diabetic patients

International Journal of Immunopathology and Pharmacology

Volumn 25, Issue 3, 2012, Pages 757-761

  Abate, M ^a   Schiavone, C ^a   Salini, V ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

Diabetes; Neoangiogenesis; Tendinopathy; Ultrasonography; Vascular endothelial growth factor

Indexed keywords

ADULT; AGED; ANGIOGENESIS; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DIABETIC PATIENT; DOPPLER ECHOGRAPHY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVALENCE; PRIORITY JOURNAL; RADIOGRAPHY; RETROSPECTIVE STUDY; TENDINITIS;

EID: 84868014563     PISSN: 03946320     EISSN: None     Source Type: Journal    
DOI: 10.1177/039463201202500322     Document Type: Article

References (16)

1. Abate M, Silbernagel KG, Siljeholm C, Di Iorio A, De Amicis D, Salini V, Werner S, Paganelli R. Pathogenesis of tendinopathies: inflammation or degeneration? Arthritis Res Ther 2009; 11( 3): 235.
2. Oliva F, Gatti S, Porcellini G, Forsyth NR, Maffulli N. Growth factors and tendon healing. Med Sport Sei 2012; 57: 53-64.
3. Abate M, Schiavone C, Pelotti P, Salini V. Limited joint mobility in diabetes and ageing: recent advances in pathogenesis and therapy. Int J Immunopathol Pharmacol 2010; 23( 4): 997-1003.
4. Brem H, Kodra A, Golinko MS, et al. Mechanism of sustained release of vascular endothelial growth factor in accelerating experimental diabetic healing. J Invest Dermatol 2009; 129( 9): 2275-87.
5. Ahluwalia A, Narula J, Jones MK, Deng X, Tarnawski AS. Impaired angiogenesis in aging myocardial microvascular endothelial cells is associated with reduced importin alpha and decreased nuclear transport of HIF1 alpha: mechanistic implications. J Physiol Pharmacol 2010; 61( 2): 133-9.
6. ADA (American Diabetes Association). Diagnosis and classification of diabetes mellitus. Diabetes Care 2011; 34( S): 62-69.
7. Grassi W, Filippucci E, Farina A, Cervini C. Sonographic imaging of tendons. Arthritis Rheum 2000; 43(5):969-76. (Pubitemid 30368172)
8. Ohberg L, Lorentzon R, Alfredson H. Neovascularisation in Achilles tendons with painful tendinosis but not in normal tendons: an ultrasonographic investigation. Knee Surg Sports Traumatol Arthrose 2001; 9(4):233-8. (Pubitemid 33684355)
9. Pufe T, Petersen WJ, Mentlein R, Tillmann BN. The role of vasculature and angiogenesis for the pathogenesis of degenerative tendons disease. Scand J Med Sci Sports 2005; 15(4):211-22. (Pubitemid 41032385)
10. Chbinou N, Frenette J. Insulin-dependent diabetes impairs the inflammatory response and delays angiogenesis following Achilles tendon injury. Am J Physiol Regul Integr Comp Physiol 2004; 286(5):R952-7. (Pubitemid 38506843)
11. Rivard A, Silver M, Chen D, Kearney M, Magner M, Annex B, Peters K, Isner JM. Rescue of diabetesrelated impairment of angiogenesis by intramuscular gene therapy with adeno-VEGF. Am J Pathol 1999; 154(2):355-63. (Pubitemid 29094086)
12. Lerman OZ, Galiano RD, Armour M, Levine JP, Gurtner GC. Cellular dysfunction in the diabetic fibroblast: impairment in migration, vascular endothelial growth factor production, and response to hypoxia. Am J Pathol 2003; 162(1):303-12. (Pubitemid 36042012)
13. Thangarajah H, Vial IN, Grogan RH, et al. HIFlalpha dysfunction in diabetes. Cell Cycle 2010; 9( 1): 75-79.
14. Shoji T, Koyama H, Morioka T, et al. Receptor for advanced glycation end products is involved in impaired angiogenic response in diabetes. Diabetes 2006; 55(8):2245-55. (Pubitemid 44743621)
15. Franke S, Sommer M, Rüster C, Bondeva T, Marticke J, Hofmann G, Hein G, Wolf G. Advanced glycation end products induce cell cycle arrest and proinflammatory changes in osteoarthritic fibroblast like synovial cells. Arthritis Res Ther 2009; 11( 5): R136.
16. van Sterkenburg MN, de Jonge MC, Sierevelt IN, van Dijk CN. Less promising results with sclerosing ethoxysclerol injections for midportion achilles tendinopathy: a retrospective study. Am J Sports Med 2010; 38( 11): 2226-32.