JAK-STAT pathway modulates the roles of iNOS and COX-2 in the cytoprotection of early phase of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress

Neuroscience Letters

Volumn 529, Issue 2, 2012, Pages 166-171

  Yu, Huimin ^a   Liu, Zhicheng ^b   Zhou, Hongzu ^b   Dai, Wei ^a   Chen, Si ^a   Shu, Yuanlan ^a   Feng, Jianqiang ^c  

^a SHENZHEN UNIVERSITY   (China)

^b SZ Hospital of Traditional Chinese Medicine   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

COX 2; Cytoprotection; Early phase; H2O2 preconditioning; INOS; JAK STAT

Indexed keywords

AMINOGUANIDINE; CYCLOOXYGENASE 2; HYDROGEN PEROXIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; JANUS KINASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NITRIC OXIDE SYNTHASE INHIBITOR; STAT PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME REGULATION; INSTRUMENTAL CONDITIONING; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; APOPTOSIS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYTOPROTECTION; ENZYME ACTIVATION; HYDROGEN PEROXIDE; JANUS KINASES; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PC12 CELLS; RATS; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 84867989104     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.09.013     Document Type: Article

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