Mouse models of breast cancer metastasis to bone

Cancer and Metastasis Reviews

Volumn 31, Issue 3-4, 2012, Pages 579-583

  Kretschmann, Kelsi L ^a   Welm, Alana L ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Bone metastasis; Breast cancer; Mouse model

Indexed keywords

DENOSUMAB; GREEN FLUORESCENT PROTEIN;

ANIMAL MODEL; ARTICLE; BIOLUMINESCENCE; BONE METASTASIS; BONE TUMOR; BREAST CANCER; CANCER GRAFT; MICRO-COMPUTED TOMOGRAPHY; MOLECULAR IMAGING; MOLECULAR PROBE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; TRANSGENIC MOUSE; X RAY;

ANIMALS; BONE NEOPLASMS; BREAST NEOPLASMS; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MICE; NEOPLASM TRANSPLANTATION; X-RAY MICROTOMOGRAPHY;

EID: 84867978881     PISSN: 01677659     EISSN: 15737233     Source Type: Journal    
DOI: 10.1007/s10555-012-9378-4     Document Type: Article

References (37)

1. American Cancer Society. (2012). Cancer facts and figures 2012. Atlanta: American Cancer Society.
2. Colman, R. E. (2002). Future directions in the treatment and prevention of bone metastasis. American Journal of Clinical Oncology, 25, S32-S38.
3. Mundy, G. R. (2002). Metastasis to bone: causes, consequences and therapeutic opportunities. Nature Reviews Cancer, 2, 584-593.
4. Deil, I. J.; Solomayer, E. F.; & Bastert, G. (2000). Treatment of metastatic bone disease in breast cancer, bisphophonates. Clinical Breast Cancer, 1, 43-51.
5. Tsukamoto, A. S.; Grosschedl, R.; Guzman, R. C.; et al. (1988). Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. Cell, 55, 619-625.
6. Guy, C. T.; Webster, M. A.; Schaller, M.; et al. (1992). Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease. Proceedings of the National Academy of Sciences of the United States of America, 89, 10578-10582.
7. Bouchard, L.; Lamarre, L.; Tremblay, P. T.; et al. (1989). Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene. Cell, 57, 931-936.
8. Muller, W. J.; Sinn, E.; Pattengale, P. K.; et al. (1988). Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene. Cell, 54, 105-115.
9. Nielsen, L. L.; Discafani, C. M.; Gurnan, M.; et al. (1991). Histopathology of salivary and mammary gland tumors in transgenic mice expressing a human Ha-ras oncogene. Cancer Research, 51, 3762-3767.
10. Sinn, E.; Muller, W.; Pattengale, P.; et al. (1987). Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo. Cell, 49, 465-475.
11. Goldstein, R. H.; Weinberg, R. A.; & Rosenblatt, M. (2010). Of mice and (wo)men: mouse models of breast cancer metastasis to bone. Journal of Bone and Mineral Research, 25, 431-436.
12. Guy, C. T.; Cardiff, R. D.; & Muller, W. J. (1992). Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease. Molecular and Cellular Biology, 12, 954-961.
13. Ichaso, N.; & Dilworth, S. M. (2001). Cell transformation by the middle T-antigen of polyoma virus. Oncogene, 20, 7908-7916.
14. Lin, E. Y.; Jones, J. G.; Li, P.; et al. (2003). Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. American Journal of Pathology, 163, 2113-2126.
15. Fluck, M. M.; & Haslam, S. Z. (1996). Mammary tumors induced by polyomavirus. Breast Cancer Research and Treatment, 39, 45-56.
16. Welm, A. L.; Sneddon, J. B.; Taylor, C.; et al. (2007). The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans. Proceedings of the National Academy of Sciences of the United States of America, 104, 7570-7575.
17. Kang, Y.; Siegel, P. M.; Shu, W.; et al. (2003). A multigenic program mediating breast cancer metastasis to bone. Cancer Cell, 3, 537-549.
18. Garcia, T.; Jackson, A.; Bachelier, R.; et al. (2008). A convenient clinically relevant model of human breast cancer to bone metastasis. Clinical & Experimental Metastasis, 25, 33-42.
19. Tavazoie, S. F.; Alarcon, C.; Oskarsson, T.; et al. (2008). Endogenous human microRNAs that suppress breast cancer metastasis. Nature, 451, 147-152.
20. Minn, A. J.; Gupta, G. P.; Siegel, P. M.; et al. (2005). Genes that mediate breast cancer metastasis to lung. Nature, 436, 518-524.
21. Bos, P. D.; Zhang, X. H.; Nadal, C.; et al. (2009). Genes that mediate breast cancer metastasis to brain. Nature, 459, 1005-1009.
22. Kakiuchi, S.; Daigo, Y.; Tsunoda, T.; et al. (2003). Genome-wide analysis of organ-preferential metastasis of human small cell lung cancer in mice. Molecular Cancer Research, 1, 485-499.
23. Juarez, P.; & Guise, T. A. (2011). TGF-β in cancer and bone: implications for treatment of bone metastasis. Bone, 48, 23-29.
24. Mundy, G. R.; Yoneda, T.; & Hiraga, T. (2001). Preclinical studies with zoledronic acid and other bisphosphonates: impact on the bone microenvironment. Seminars in Oncology, 28(2 Suppl 6), 35-44.
25. Canon, J. R.; Roudier, M.; Bryant, R.; et al. (2008). Inhibition of RANKL blocks skeletal tumor progression and improves survival in a mouse model of breast cancer bone metastasis. Clinical & Experimental Metastasis, 25, 119-129.
26. Valastyan, S.; & Weinberg, R. A. (2011). Tumor metastasis: molecular insights and evolving paradigms. Cell, 147, 275-292.
27. Lelekakis, M.; Moseley, J. M.; Martin, T. J.; et al. (1999). A novel orthotopic model of breast cancer metastasis to bone. Clinical & Experimental Metastasis, 17, 163-170.
28. Miller, F. R.; Miller, B. E.; & Heppner, G. H. (1983). Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor:heterogeneity in phenotypic stability. Invasion and Metastasis, 3, 22-31.
29. DeNardo, D. G.; & Coussens, L. M. (2007). Inflammation and breast cancer-balancing immune response: crosstalk between adaptive and innate immune cells during breast cancer progression. Breast Cancer Research, 9, 212.
30. Kuperwasser, C.; Chavarria, T.; Wu, M.; et al. (2004). Reconstitution of functionally normal and malignant human breast tissues in mice. Proceedings of the National Academy of Sciences of the United States of America, 101, 4966-4972.
31. Kuperwasser, C.; Dessain, S.; Bierbaum, B. E.; et al. (2005). A mouse model of human breast cancer metastasis to human bone. Cancer Research, 65, 6130-6138.
32. Moreau, J. E.; Anderson, K.; Mauney, J. R.; et al. (2007). Tissue-engineered bone serves as a target for metastasis of human breast cancer in a mouse model. Cancer Research, 67, 10304-10308.
33. DeRose, Y. S.; Wang, G.; Lin, Y. C.; et al. (2011). Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nature Medicine, 17, 1514-1520.
34. Weissleder, R.; Tung, C. H.; Mahmood, U.; et al. (1999). In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nature Biotechnology, 17, 375-378.
35. Henriquez, N. V.; van Overveld, P. G.; Que, I.; et al. (2007). Advances in optical imaging and novel systems for cancer metastasis research. Clinical & Experimental Metastasis, 24, 699-705.
36. Serganova, I.; Moroz, E.; Vider, J.; et al. (2009). Multimodality imaging of TGFbeta signaling in breast cancer metastases. The FASEB Journal, 23, 2662-2672.
37. Korpal, M.; Yan, J.; Lu, X.; et al. (2009). Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis. Nature Medicine, 15(8), 960-966.