Exposure to organochlorine pesticides is an independent risk factor of hepatocellular carcinoma: A casecontrol study

Journal of Exposure Science and Environmental Epidemiology

Volumn 22, Issue 6, 2012, Pages 541-548

  Zhao, Benhua ^a   Shen, Heqing ^b   Liu, Feng ^b   Liu, Sheng ^a   Niu, Jianjun ^c   Guo, Fei ^a   Sun, Xueli ^d  

^a XIAMEN UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c Xiamen Center for Disease Control and Prevention   (China)

^d Zhangzhou Center for Disease Control and Prevention   (China)

Author keywords

case control study; human exposure; organochlorine pesticides; primary hepatocellular carcinoma; risk factor interaction.

Indexed keywords

CHLORINATED HYDROCARBON; PESTICIDE;

ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CHEMICALLY INDUCED DISORDER; FEMALE; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; MIDDLE AGED; PATHOLOGY; RISK FACTOR;

ADULT; AGED; CARCINOMA, HEPATOCELLULAR; CASE-CONTROL STUDIES; FEMALE; HUMANS; HYDROCARBONS, CHLORINATED; LIVER NEOPLASMS; MALE; MIDDLE AGED; PESTICIDES; RISK FACTORS;

HEPATITIS B VIRUS;

EID: 84867898815     PISSN: 15590631     EISSN: 1559064X     Source Type: Journal    
DOI: 10.1038/jes.2011.29     Document Type: Article

References (55)

1. Altekruse S.F., McGlynn K.A., and Reichman M.E. Hepatocellular carcinoma incidence, mortality, and survival trends in the united states from 1975 to 2005. J Clin Oncol 2009: 27: 1485-1491.
2. Chu F.S., and Li G.Y. Simultaneous occurrence of fumonisin B-1 and other mycotoxins in moldy corn collected from the Peoples-Republic-Of-China in regions with high incidences of esophageal cancer. Appl Environ Microbiol 1994: 60: 847-852. (Pubitemid 24077972)
3. Codru N., Schymura M.J., Negoita S., Rej R., Carpenter D.O., and Env A.T.F. Diabetes an relation to serum levels of polychlorinated biphenyls and chlorinated pesticides an adult native Americans. Environ Health Perspect 2007: 115: 1442-1447. (Pubitemid 47618086)
4. Cocco P., Blair A., Congia P., Saba G., Flore C., and Ecca M.R., et al. Proportional mortality of dichloro-diphenyl-trichloroethane (DDT) workers: A preliminary report. Arch Environ Health 1997: 52: 299-303. (Pubitemid 27265641)
5. Cocco P., Fadda D., Billai B., D'Atri M., Melis M., and Blair A. Cancer mortality among men occupationally exposed to dichlorodiphenyltrichloroethane. Cancer Res 2005: 65: 9588-9594. (Pubitemid 41508030)
6. Cocco P., Kazerouni N., and Zahm S.H. Cancer mortality and environmental exposure to DDE in the United States. Environ Health Perspect 2000: 108: 1-4. (Pubitemid 30064088)
7. Dekoning E.P., and Karmaus W. PCB exposure in utero and via breast milk. A review. J Expo Anal Environ Epidemiol 2000: 10: 285-293. (Pubitemid 30463349)
8. Deng Z.L., Ma Y., Pan L.X., and Peng H.Z. A molecular epidemiologic marker of hepatocellular carcinoma from aflatoxin B1 contaminated area in the Southwest of Guangxi, China. J Cancer Res 1997: 9: 167-169.
9. Donato F., Tagger A., Gelatti U., Parrinello G., Boffetta P., and Albertini A., et al. Alcohol and hepatocellular carcinoma: the effect of lifetime intake and hepatitis virus infections in men and women. Amer J Epidemiol 2002: 155: 323-331. (Pubitemid 34132050)
10. El-Serag H.B., and Rudolph L. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007: 132: 2557-2576. (Pubitemid 46890874)
11. El-Shahawi M.S., Hamza A., Bashammakh A.S., and Al-Saggaf W.T. An overview on the accumulation, distribution, transformations, toxicity and analytical methods for the monitoring of persistent organic pollutants. Talanta 2010: 80: 1587-1597.
12. Eskenazi B., Chevrier J., Rosas L.G., Anderson H.A., Bornman M.S., and Bouwman H., et al. The pine river statement: human health consequences of DDT use. Environ Health Perspect 2009: 117: 1359-1367.
13. Figatalamanca I., Mearelli I., and Valente P. Mortality in a cohort of pesticide applicators in an urban setting. Int J Epidemiol 1993: 22: 674-676. (Pubitemid 23247570)
14. Garcia M., Jemal A., Ward E.M., Center M.M., Hao Y., and Siegel R.L., et al. Global Cancer Facts & Figures 2007. American Cancer Society, Atlanta, GA, 2007.
15. Hassan M.M., Spitz M.R., Thomas M.B., El-Deeb A.S., Glover K.Y., and Nguyen N.T. et al. Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: case-control study. Int J Cancer 2008: 123: 1883-1891.
16. Imai Y., Tamura S., Tanaka H., Hiramatsu N., Kiso S., and Doi Y., et al. Reduced risk of hepatocellular carcinoma after interferon therapy in aged patients with chronic hepatitis C is limited to sustained virological responders. J Viral Hepatitis 2010: 17: 185-191.
17. Jaga K., and Dharmani C. Global surveillance of DDTand DDE levels in human tissues. Int J Occup Med Environ Health 2003: 16: 7-20. (Pubitemid 36458532)
18. Jemal A., Siegel R., Ward E., Hao Y., Xu J., and Thun M.J. Cancer statistics 2009. CA Cancer J Clin 2009: 59: 225-249.
19. Parkin D.M., Bray F., Ferlay J., and Pisani P. Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001: 94: 153-156. (Pubitemid 32911406)
20. Kä llberg H., Ahlbom A., and Alfredsson L. Calculating measures of biological interaction using R. Eur J Epidemiol 2006 21 571-573.
21. Kirk G.D., Camus-Randon A.M.,MendyM., Goedert J.J., Merle P., and Trepo C., et al. Ser-249 p53 mutations in plasma DNA of patients with hepatocellular carcinoma from The Gambia. J Natl Cancer Inst 2000: 92: 148-153. (Pubitemid 30089872)
22. Kitagawa T., Hino O., Nomura K., and Sugano H. Dose-response studies on promoting and anticarcinogenic effects of phenobarbital and DDT in the rat hepatocarcinogenesis. Carcinogenesis 1984: 5: 1653-1656. (Pubitemid 15127033)
23. Li F.Q., Yoshizawa T., Kawamura O., Luo X.Y., and Li Y.W. Aflatoxins and fumonisins in corn from the high-incidence area for human hepatocellular carcinoma in Guangxi, China. J Agric Food Chem 2001: 49: 4122-4126. (Pubitemid 32822745)
24. Liu L.F., Zhang J.L., Chen Q., Chang Y., and Lin J.S. Cyclooxygenase-2 gene-1195G/A genotype is associated with the risk of HBV-induced HCC: a casecontrol study in Han Chinese people. Front Med China 2010: 4: 6.
25. Liu Y., andWu F. Global burden of aflatoxin-induced hepatocellular carcinoma: a risk assessment. Environ Health Perspect 2010: 118: 818-824.
26. McGlynn K.A., Abnet C.C., Zhang M., Sun X.D., Fan J.H., and O'Brien T.R., et al. Serum concentrations of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) and risk of primary liver cancer. J Natl Cancer Inst 2006: 98: 1005-1010. (Pubitemid 44288165)
27. McGlynn K.A., and London W.T. Epidemiology and natural history of hepatocellular carcinoma. Best Pract Res Clin Gastroenterol 2005: 19: 3-23. (Pubitemid 40331495)
28. Morgan D.P., and Roan C.C. Absorption, storage, and metabolic conversion of ingested DDT and DDT metabolites in man. Arch Environ Health 1971: 22: 301-308.
29. Niu J.J., Su Y.H., Han Y.F., Zhao R., Sun X.L., and Guo F., et al. Synergistic effects of different types of smoking and other risk factors on risk of hepatocellular carcinoma in Xiamen, China. Chin J Epidemiol 2010: 31: 6.
30. Onishchenko N., Karpova N., Sabri F., Castren E., and Ceccatelli S. Long-lasting depression-like behavior and epigenetic changes of BDNF gene expression induced by perinatal exposure to methylmercury. J Neurochem 2008: 106: 1378-1387.
31. Parkin D.M., Bray F., Ferlay J., and Pisani P. Global cancer statistics 2002. CA Cancer J Clin 2005: 55: 74-108.
32. POPRC. Risk Profile on Beta Hexachlorocyclohexane, Addendum of the Report of the Persistent Organic Pollutants Review Committee (POPRC) on the Work of its Third Meeting, Geneva, Switzerland, 2007. http://www.pops.int/documents/ meetings/poprc/POPRC3-report.htm (accessed on 22 July 2010).
33. Qian G.S., Ross R.K., Yu M.C., Yuan J.M., Gao Y.T., and Henderson B.E., et al. A follow-up study of urinary markers of aflatoxin exposure and liver cancer risk in Shanghai, People's Republic of China. Cancer Epidemiol Biomarkers Prev 1994: 3: 3-10. (Pubitemid 24172514)
34. Qiu X., Zhu T., Yao B., Hu J., and Hu S. Contribution of dicofol to the current DDT pollution in China. Environ Sci Technol 2005: 39: 4385-4390. (Pubitemid 40853119)
35. Qu C.X., Kamangar F., Fan J.H., Yu B., Sun X.D., and Taylor P.R., et al. Chemoprevention of primary liver cancer: a randomized, double-blind trial in Linxian, China. J Natl Cancer Inst 2007: 99: 1240-1247. (Pubitemid 47299902)
36. Ruzzin J., Petersen R., Meugnier E., Madsen L., Lock E.J., and Lillefosse H., et al. Persistent organic pollutant exposure leads to insulin resistance syndrome. Environ Health Perspect 2010: 118: 465-471.
37. Shen H., Maine K.M., Andersson A.M., Damgaard I.N., Virtanen H.E., and Skakkebaek N.E., et al. Concentrations of persistent organochlorine compounds in human milk and placenta are higher in Denmark than in Finland. Hum Reprod 2008: 23: 201-210. (Pubitemid 351767306)
38. Shen F.M., Lee M.K., Gong H.M., Cai X.Q., and King M.C. Complex segregation analysis of primary hepatocellular carcinoma in Chinese families: interaction of inherited susceptibility and hepatitis B viral infection. Am J Hum Genet 1991: 49: 88-93. (Pubitemid 21891656)
39. Shen H., Main K.M., Virtanen H.E., Damggard I.N., Haavisto A.M., and Kaleva M., et al. From mother to child: Investigation of prenatal and postnatal exposure to persistent bioaccumulating toxicants using breast milk and placenta biomonitoring. Chemosphere 2007: 67: S256-S262. (Pubitemid 46367162)
40. Sundberg S.E., Ellington J.J., and Evans J.J. A simple and fast extraction method for organochlorine pesticides and polychlorinated biphenyls in small volumes of avian serum. J Chromatogr B 2006: 831: 99-104. (Pubitemid 43158389)
41. Szymanska K., Chen J.G., Cui Y., Gong Y.Y., Turner P.C., and Villar S., et al. TP53 R249S mutations, exposure to aflatoxin, and occurrence of hepatocellular carcinoma in a cohort of chronic hepatitis B virus carriers from Qidong, China. Cancer Epidemiol Biomarkers Prev 2009: 18: 1638-1643.
42. Vetter W, and Schurig V. Enantioselective determination of chiral organochlorine compounds in biota by gas chromatography on modified cyclodextrins. J Chromatogr A 1997: 774: 143-175. (Pubitemid 27300245)
43. Wang J., and Liu X.M. Contamination of aflatoxins in different kinds of foods in China. Biomed Environ Sci 2007: 20: 483-487. (Pubitemid 351224812)
44. Wang J.S., Huang T., Su J.J., Liang F., Wei Z.L., and Liang Y.Q., et al. Hepatocellular carcinoma and aflatoxin exposure in Zhuqing Village, Fusui County, People's Republic of China. Cancer Epidemiol Biomarker Prev 2001: 10: 143-146. (Pubitemid 32172434)
45. Wang X.Q., Gao P.Y., Lin Y.Z., and Chen C.M. Studies on hexachlorocyclohexane and DDTcontents in human cerumen and their relationships to cancer mortality. Biomed Environ Sci 1988: 1: 138-151.
46. Welzel T.M., Katki H.A., Sakoda L.C., Evans A.A., LondonW.T., and Chen G., et al. Blood folate levels and risk of liver damage and hepatocellular carcinoma in a prospective high-risk cohort. Cancer Epidemiol Biomarkers Prev 2007: 16: 1279-1282. (Pubitemid 46984971)
47. WHO. Environmental Health Criteria 123, Alpha-and beta- Hexachlorocyclohexanes, Geneva, Switzerland, 1992. http://www.inchem.org/ documents/ehc/ehc/ehc123.htm (accessed on 2 November 2010).
48. WHO/IDF. Definition and Diagnosis of Diabetes Mellitus and Intermediate Hyperglycemia: A Report of WHO/IDF Consultation, Geneva, Switzerland, 2006. http://www.who.int/diabetes/publications/en/(accessed on 28 July 2010).
49. Willett K.L., Ulrich E.M., and Hites R.A. Differential toxicity and environmental fates of hexachlorocyclohexane isomers. Environ Sci Technol 1998: 32: 2197-2207. (Pubitemid 28359854)
50. Williams G.M., and Numoto S. Promotion of mouse liver neoplasms by the organochlorine pesticides chlordane and heptachlor in comparison to dichlorodiphenyltrichloroethane. Carcinogenesis 1984: 5: 1689-1696. (Pubitemid 15127038)
51. Wu H.C., Wang Q., Wang L.W., Yang H.I., Ahsan H., and Tsai W.Y., et al. Polycyclic aromatic hydrocarbon-and aflatoxin-albumin adducts, hepatitis B virus infection and hepatocellular carcinoma in Taiwan. Cancer Lett 2007: 252: 104-114. (Pubitemid 46734557)
52. Wu H.C., Wang Q., Yang H.I., Ahsan H., Tsai W.Y., and Wang L.Y., et al. Urinary 15-F-2t-isoprostane, aflatoxin B-1 exposure and hepatitis B virus infection and hepatocellular carcinoma in Taiwan. Carcinogenesis 2008: 29: 971-976. (Pubitemid 351982242)
53. Yang L., Parkin D.M., Whelan S., Zhang S., Chen Y., and Lu F., et al. Statistics on cancer in China: cancer registration in 2002. Eur J Cancer Prev 2005: 14: 329-335. (Pubitemid 41104940)
54. Yeh F.S., Yu M.C., Mo C.C., Luo S., Tong M.J., and Henderson B.E. Hepatitis B virus, aflatoxins, and hepatocellular carcinoma in southern Guangxi, China. Cancer Res 1989: 49: 2506-2509. (Pubitemid 19125586)
55. Zhao B.H., Guo F., Liu S., and Pan L.L. The study on the interactions between polycyclic aromatic hydrocarbon-albumin adducts and various risk factors to primary hepatocellular carcinoma. Chin J Prev Med 2010: 44: 427-432.