메뉴 건너뛰기




Volumn 28, Issue 11, 2012, Pages 522-529

Phenotypic and genotypic characterisation of drug-resistant Plasmodium vivax

Author keywords

Chloroquine; Clinical trials; Drug resistance; Genotyping; In vitro drug susceptibility test; Malaria; Molecular markers; Plasmodium vivax

Indexed keywords

BIOLOGICAL MARKER; CHLOROQUINE; FOLIC ACID ANTAGONIST; MEFLOQUINE; PIPERAQUINE; PRIMAQUINE;

EID: 84867891053     PISSN: 14714922     EISSN: 14715007     Source Type: Journal    
DOI: 10.1016/j.pt.2012.08.005     Document Type: Review
Times cited : (67)

References (90)
  • 2
    • 0024387301 scopus 로고
    • Plasmodium vivax resistance to chloroquine?
    • Rieckmann K.H., et al. Plasmodium vivax resistance to chloroquine?. Lancet 1989, 2:1183-1184.
    • (1989) Lancet , vol.2 , pp. 1183-1184
    • Rieckmann, K.H.1
  • 3
    • 0025916839 scopus 로고
    • Resistance to chloroquine by Plasmodium vivax in Irian Jaya, Indonesia
    • Baird J.K., et al. Resistance to chloroquine by Plasmodium vivax in Irian Jaya, Indonesia. Am. J. Trop. Med. Hyg. 1991, 44:547-552.
    • (1991) Am. J. Trop. Med. Hyg. , vol.44 , pp. 547-552
    • Baird, J.K.1
  • 4
    • 84873077842 scopus 로고    scopus 로고
    • Diagnosis and treatment of Plasmodium vivax malaria
    • Adv. Parasitol. (in press)
    • Baird, J.K. et al. Diagnosis and treatment of Plasmodium vivax malaria. Adv. Parasitol. (in press).
    • Baird, J.K.1
  • 5
    • 40049109886 scopus 로고    scopus 로고
    • Vivax malaria: neglected and not benign
    • Price R.N., et al. Vivax malaria: neglected and not benign. Am. J. Trop. Med. Hyg. 2007, 77:79-87.
    • (2007) Am. J. Trop. Med. Hyg. , vol.77 , pp. 79-87
    • Price, R.N.1
  • 6
    • 66949112575 scopus 로고    scopus 로고
    • Vivax malaria: a major cause of morbidity in early infancy
    • Poespoprodjo J.R., et al. Vivax malaria: a major cause of morbidity in early infancy. Clin. Infect. Dis. 2009, 48:1704-1712.
    • (2009) Clin. Infect. Dis. , vol.48 , pp. 1704-1712
    • Poespoprodjo, J.R.1
  • 7
    • 42549139438 scopus 로고    scopus 로고
    • Adverse pregnancy outcomes in an area where multidrug-resistant Plasmodium vivax and Plasmodium falciparum infections are endemic
    • Poespoprodjo J.R., et al. Adverse pregnancy outcomes in an area where multidrug-resistant Plasmodium vivax and Plasmodium falciparum infections are endemic. Clin. Infect. Dis. 2008, 46:1374-1381.
    • (2008) Clin. Infect. Dis. , vol.46 , pp. 1374-1381
    • Poespoprodjo, J.R.1
  • 8
    • 77950937335 scopus 로고    scopus 로고
    • Severe congenital malaria acquired in utero
    • Poespoprodjo J.R., et al. Severe congenital malaria acquired in utero. Am. J. Trop. Med. Hyg. 2010, 82:563-565.
    • (2010) Am. J. Trop. Med. Hyg. , vol.82 , pp. 563-565
    • Poespoprodjo, J.R.1
  • 9
    • 65349181325 scopus 로고    scopus 로고
    • The pathophysiology of vivax malaria
    • Anstey N.M., et al. The pathophysiology of vivax malaria. Trends Parasitol. 2009, 25:220-227.
    • (2009) Trends Parasitol. , vol.25 , pp. 220-227
    • Anstey, N.M.1
  • 10
    • 46349102897 scopus 로고    scopus 로고
    • Multidrug-resistant Plasmodium vivax Associated with severe and fatal malaria: a prospective study in Papua, Indonesia
    • Tjitra E., et al. Multidrug-resistant Plasmodium vivax Associated with severe and fatal malaria: a prospective study in Papua, Indonesia. PLoS Med. 2008, 5:e128.
    • (2008) PLoS Med. , vol.5
    • Tjitra, E.1
  • 11
    • 46349109749 scopus 로고    scopus 로고
    • Plasmodium vivax and mixed infections are associated with severe malaria in children: a prospective cohort study from Papua New Guinea
    • Genton B., et al. Plasmodium vivax and mixed infections are associated with severe malaria in children: a prospective cohort study from Papua New Guinea. PLoS Med. 2008, 5:e127.
    • (2008) PLoS Med. , vol.5
    • Genton, B.1
  • 12
    • 0042307256 scopus 로고    scopus 로고
    • Very high risk of therapeutic failure with chloroquine for uncomplicated Plasmodium falciparum and Plasmodium falciparum malaria in Indonesian Papua
    • Sumawinata I.W., et al. Very high risk of therapeutic failure with chloroquine for uncomplicated Plasmodium falciparum and Plasmodium falciparum malaria in Indonesian Papua. Am. J. Trop. Med. Hyg. 2003, 68:416-420.
    • (2003) Am. J. Trop. Med. Hyg. , vol.68 , pp. 416-420
    • Sumawinata, I.W.1
  • 13
    • 33846783000 scopus 로고    scopus 로고
    • Therapeutic response of multidrug-resistant Plasmodium falciparum and Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia
    • Ratcliff A., et al. Therapeutic response of multidrug-resistant Plasmodium falciparum and Plasmodium falciparum to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia. Trans. R. Soc. Trop. Med. Hyg. 2007, 101:351-359.
    • (2007) Trans. R. Soc. Trop. Med. Hyg. , vol.101 , pp. 351-359
    • Ratcliff, A.1
  • 14
    • 57749116211 scopus 로고    scopus 로고
    • A trial of combination antimalarial therapies in children from Papua New Guinea
    • Karunajeewa H.A., et al. A trial of combination antimalarial therapies in children from Papua New Guinea. N. Engl. J. Med. 2008, 359:2545-2557.
    • (2008) N. Engl. J. Med. , vol.359 , pp. 2545-2557
    • Karunajeewa, H.A.1
  • 15
    • 70349158714 scopus 로고    scopus 로고
    • New developments in Plasmodium vivax malaria: severe disease and the rise of chloroquine resistance
    • Price R.N., et al. New developments in Plasmodium vivax malaria: severe disease and the rise of chloroquine resistance. Curr. Opin. Infect. Dis. 2009, 22:430-435.
    • (2009) Curr. Opin. Infect. Dis. , vol.22 , pp. 430-435
    • Price, R.N.1
  • 16
    • 77952605533 scopus 로고    scopus 로고
    • Artemisinin combination therapy for vivax malaria
    • Douglas N.M., et al. Artemisinin combination therapy for vivax malaria. Lancet Infect. Dis. 2010, 10:405-416.
    • (2010) Lancet Infect. Dis. , vol.10 , pp. 405-416
    • Douglas, N.M.1
  • 17
    • 84873081460 scopus 로고    scopus 로고
    • Genotyping to identify parasite populations
    • World Health Organization and Medicines for Malaria Venture, World Health Organization
    • World Health Organization and Medicines for Malaria Venture Genotyping to identify parasite populations. Methods and Techniques for Clinical Trials on Antimalarial Drug Efficacy 2008, World Health Organization. http://www.who.int/malaria/publications/atoz/9789241596305/en/.
    • (2008) Methods and Techniques for Clinical Trials on Antimalarial Drug Efficacy
  • 18
    • 21444453280 scopus 로고    scopus 로고
    • Practical PCR genotyping protocols for Plasmodium vivax using Pvcs and Pvmsp1
    • Imwong M., et al. Practical PCR genotyping protocols for Plasmodium vivax using Pvcs and Pvmsp1. Malar. J. 2005, 4:20.
    • (2005) Malar. J. , vol.4 , pp. 20
    • Imwong, M.1
  • 19
    • 33947393043 scopus 로고    scopus 로고
    • Relapses of Plasmodium vivax infection result from clonal hypnozoites activated at predetermined intervals
    • Chen N., et al. Relapses of Plasmodium vivax infection result from clonal hypnozoites activated at predetermined intervals. J. Infect. Dis. 2007, 195:934-941.
    • (2007) J. Infect. Dis. , vol.195 , pp. 934-941
    • Chen, N.1
  • 20
    • 65549115512 scopus 로고    scopus 로고
    • Evaluation of Plasmodium vivax genotyping markers for molecular monitoring in clinical trials
    • Koepfli C., et al. Evaluation of Plasmodium vivax genotyping markers for molecular monitoring in clinical trials. J. Infect. Dis. 2009, 199:1074-1080.
    • (2009) J. Infect. Dis. , vol.199 , pp. 1074-1080
    • Koepfli, C.1
  • 21
    • 80051826924 scopus 로고    scopus 로고
    • Characterization of treatment failure in efficacy trials of drugs against Plasmodium vivax by genotyping neutral and drug resistance-associated markers
    • Barnadas C., et al. Characterization of treatment failure in efficacy trials of drugs against Plasmodium vivax by genotyping neutral and drug resistance-associated markers. Antimicrob. Agents Chemother. 2011, 55:4479-4481.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 4479-4481
    • Barnadas, C.1
  • 22
    • 33947431664 scopus 로고    scopus 로고
    • Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites
    • Imwong M., et al. Relapses of Plasmodium vivax infection usually result from activation of heterologous hypnozoites. J. Infect. Dis. 2007, 195:927-933.
    • (2007) J. Infect. Dis. , vol.195 , pp. 927-933
    • Imwong, M.1
  • 23
    • 34249997585 scopus 로고    scopus 로고
    • Contrasting genetic structure in Plasmodium vivax populations from Asia and South America
    • Imwong M., et al. Contrasting genetic structure in Plasmodium vivax populations from Asia and South America. Int. J. Parasitol. 2007, 37:1013-1022.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 1013-1022
    • Imwong, M.1
  • 24
    • 80053624564 scopus 로고    scopus 로고
    • Determinants of relapse periodicity in Plasmodium vivax malaria
    • White N.J. Determinants of relapse periodicity in Plasmodium vivax malaria. Malar. J. 2011, 10:297.
    • (2011) Malar. J. , vol.10 , pp. 297
    • White, N.J.1
  • 25
    • 0030877592 scopus 로고    scopus 로고
    • Diagnosis of resistance to chloroquine by Plasmodium vivax: timing of recurrence and whole blood chloroquine levels
    • Baird J.K., et al. Diagnosis of resistance to chloroquine by Plasmodium vivax: timing of recurrence and whole blood chloroquine levels. Am. J. Trop. Med. Hyg. 1997, 56:621-626.
    • (1997) Am. J. Trop. Med. Hyg. , vol.56 , pp. 621-626
    • Baird, J.K.1
  • 26
    • 0036790841 scopus 로고    scopus 로고
    • The assessment of antimalarial drug efficacy
    • White N.J. The assessment of antimalarial drug efficacy. Trends Parasitol. 2002, 18:458-464.
    • (2002) Trends Parasitol. , vol.18 , pp. 458-464
    • White, N.J.1
  • 27
    • 80054767617 scopus 로고    scopus 로고
    • Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial
    • Phyo A.P., et al. Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial. Clin. Infect. Dis. 2011, 53:977-984.
    • (2011) Clin. Infect. Dis. , vol.53 , pp. 977-984
    • Phyo, A.P.1
  • 28
    • 33846849862 scopus 로고    scopus 로고
    • Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison
    • Ratcliff A., et al. Two fixed-dose artemisinin combinations for drug-resistant falciparum and vivax malaria in Papua, Indonesia: an open-label randomised comparison. Lancet 2007, 369:757-765.
    • (2007) Lancet , vol.369 , pp. 757-765
    • Ratcliff, A.1
  • 29
    • 35248823116 scopus 로고    scopus 로고
    • World Antimalarial Resistance Network (WARN) II: in vitro antimalarial drug susceptibility
    • Bacon D.J., et al. World Antimalarial Resistance Network (WARN) II: in vitro antimalarial drug susceptibility. Malar. J. 2007, 6:120.
    • (2007) Malar. J. , vol.6 , pp. 120
    • Bacon, D.J.1
  • 30
    • 33847158906 scopus 로고    scopus 로고
    • Short-term in vitro culture of field isolates of Plasmodium vivax using umbilical cord blood
    • Udomsangpetch R., et al. Short-term in vitro culture of field isolates of Plasmodium vivax using umbilical cord blood. Parasitol. Int. 2007, 56:65-69.
    • (2007) Parasitol. Int. , vol.56 , pp. 65-69
    • Udomsangpetch, R.1
  • 31
    • 0030927831 scopus 로고    scopus 로고
    • Continuous in vitro propagation of the malaria parasite Plasmodium vivax
    • Golenda C.F., et al. Continuous in vitro propagation of the malaria parasite Plasmodium vivax. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:6786-6791.
    • (1997) Proc. Natl. Acad. Sci. U.S.A. , vol.94 , pp. 6786-6791
    • Golenda, C.F.1
  • 32
    • 33644845894 scopus 로고    scopus 로고
    • Clinical-parasitological response and in-vitro sensitivity of Plasmodium vivax to chloroquine and quinine on the western border of Thailand
    • Tasanor O., et al. Clinical-parasitological response and in-vitro sensitivity of Plasmodium vivax to chloroquine and quinine on the western border of Thailand. Trans. R. Soc. Trop. Med. Hyg. 2006, 100:410-418.
    • (2006) Trans. R. Soc. Trop. Med. Hyg. , vol.100 , pp. 410-418
    • Tasanor, O.1
  • 33
    • 12244307892 scopus 로고    scopus 로고
    • Simple in vitro assay for determining the sensitivity of Plasmodium vivax isolates from fresh human blood to antimalarials in areas where Plasmodium falciparum is endemic
    • Russell B.M., et al. Simple in vitro assay for determining the sensitivity of Plasmodium vivax isolates from fresh human blood to antimalarials in areas where Plasmodium falciparum is endemic. Antimicrob. Agents Chemother. 2003, 47:170-173.
    • (2003) Antimicrob. Agents Chemother. , vol.47 , pp. 170-173
    • Russell, B.M.1
  • 34
    • 1942501224 scopus 로고    scopus 로고
    • In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand
    • Chotivanich K., et al. In vitro efficacy of antimalarial drugs against Plasmodium vivax on the western border of Thailand. Am. J. Trop. Med. Hyg. 2004, 70:395-397.
    • (2004) Am. J. Trop. Med. Hyg. , vol.70 , pp. 395-397
    • Chotivanich, K.1
  • 35
    • 34250219978 scopus 로고    scopus 로고
    • Improved assessment of Plasmodium vivax response to antimalarial drugs by a colorimetric double-site Plasmodium lactate dehydrogenase antigen capture enzyme-linked immunosorbent assay
    • Druilhe P., et al. Improved assessment of Plasmodium vivax response to antimalarial drugs by a colorimetric double-site Plasmodium lactate dehydrogenase antigen capture enzyme-linked immunosorbent assay. Antimicrob. Agents Chemother. 2007, 51:2112-2116.
    • (2007) Antimicrob. Agents Chemother. , vol.51 , pp. 2112-2116
    • Druilhe, P.1
  • 36
    • 40549118492 scopus 로고    scopus 로고
    • Determinants of in vitro drug susceptibility testing of Plasmodium vivax
    • Russell B., et al. Determinants of in vitro drug susceptibility testing of Plasmodium vivax. Antimicrob. Agents Chemother. 2008, 52:1040-1045.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 1040-1045
    • Russell, B.1
  • 37
    • 33746874044 scopus 로고    scopus 로고
    • Plasmodium vivax: isotopic, PicoGreen, and microscopic assays for measuring chloroquine sensitivity in fresh and cryopreserved isolates
    • Kosaisavee V., et al. Plasmodium vivax: isotopic, PicoGreen, and microscopic assays for measuring chloroquine sensitivity in fresh and cryopreserved isolates. Exp. Parasitol. 2006, 114:34-39.
    • (2006) Exp. Parasitol. , vol.114 , pp. 34-39
    • Kosaisavee, V.1
  • 38
    • 84859738849 scopus 로고    scopus 로고
    • A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development
    • Malleret B., et al. A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development. Sci. Rep. 2011, 1:118.
    • (2011) Sci. Rep. , vol.1 , pp. 118
    • Malleret, B.1
  • 39
    • 0036092745 scopus 로고    scopus 로고
    • Sensitivity of Plasmodium vivax to chloroquine in Sa Kaeo Province, Thailand
    • Congpuong K., et al. Sensitivity of Plasmodium vivax to chloroquine in Sa Kaeo Province, Thailand. Acta Trop. 2002, 83:117-121.
    • (2002) Acta Trop. , vol.83 , pp. 117-121
    • Congpuong, K.1
  • 40
    • 40549103634 scopus 로고    scopus 로고
    • Chloroquine resistant Plasmodium vivax: in vitro characterisation and association with molecular polymorphisms
    • Suwanarusk R., et al. Chloroquine resistant Plasmodium vivax: in vitro characterisation and association with molecular polymorphisms. PLoS ONE 2007, 2:e1089.
    • (2007) PLoS ONE , vol.2
    • Suwanarusk, R.1
  • 41
    • 47149090556 scopus 로고    scopus 로고
    • Plasmodium vivax trophozoites insensitive to chloroquine
    • Sharrock W.W., et al. Plasmodium vivax trophozoites insensitive to chloroquine. Malar. J. 2008, 7:94.
    • (2008) Malar. J. , vol.7 , pp. 94
    • Sharrock, W.W.1
  • 42
    • 84865957899 scopus 로고    scopus 로고
    • An analytical method for assessing stage-specific drug activity in Plasmodium vivax malaria: implications for ex vivo drug susceptibility testing
    • Kerlin D.H., et al. An analytical method for assessing stage-specific drug activity in Plasmodium vivax malaria: implications for ex vivo drug susceptibility testing. PLoS Negl. Trop. Dis. 2012, 6:e1772.
    • (2012) PLoS Negl. Trop. Dis. , vol.6
    • Kerlin, D.H.1
  • 43
    • 62949122535 scopus 로고    scopus 로고
    • In vivo and in vitro efficacy of amodiaquine monotherapy for treatment of infection by chloroquine-resistant Plasmodium vivax
    • Hasugian A.R., et al. In vivo and in vitro efficacy of amodiaquine monotherapy for treatment of infection by chloroquine-resistant Plasmodium vivax. Antimicrob. Agents Chemother. 2009, 53:1094-1099.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 1094-1099
    • Hasugian, A.R.1
  • 44
    • 54949093986 scopus 로고    scopus 로고
    • Amplification of pvmdr1 associated with multidrug-resistant Plasmodium vivax
    • Suwanarusk R., et al. Amplification of pvmdr1 associated with multidrug-resistant Plasmodium vivax. J. Infect. Dis. 2008, 198:1558-1564.
    • (2008) J. Infect. Dis. , vol.198 , pp. 1558-1564
    • Suwanarusk, R.1
  • 45
    • 66949175940 scopus 로고    scopus 로고
    • Antimalarial drug susceptibility of Plasmodium vivax in the Republic of Korea
    • Chotivanich K., et al. Antimalarial drug susceptibility of Plasmodium vivax in the Republic of Korea. Am. J. Trop. Med. Hyg. 2009, 80:902-904.
    • (2009) Am. J. Trop. Med. Hyg. , vol.80 , pp. 902-904
    • Chotivanich, K.1
  • 46
    • 46249098615 scopus 로고    scopus 로고
    • Stronger activity of human immunodeficiency virus type 1 protease inhibitors against clinical isolates of Plasmodium vivax than against those of P. falciparum
    • Lek-Uthai U., et al. Stronger activity of human immunodeficiency virus type 1 protease inhibitors against clinical isolates of Plasmodium vivax than against those of P. falciparum. Antimicrob. Agents Chemother. 2008, 52:2435-2441.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 2435-2441
    • Lek-Uthai, U.1
  • 47
    • 79952341758 scopus 로고    scopus 로고
    • Ex vivo activity of histone deacetylase inhibitors against multidrug-resistant clinical isolates of Plasmodium falciparum and Plasmodium falciparum
    • Marfurt J., et al. Ex vivo activity of histone deacetylase inhibitors against multidrug-resistant clinical isolates of Plasmodium falciparum and Plasmodium falciparum. Antimicrob. Agents Chemother. 2011, 55:961-966.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 961-966
    • Marfurt, J.1
  • 48
    • 80051807653 scopus 로고    scopus 로고
    • Ex vivo drug susceptibility of ferroquine against chloroquine-resistant isolates of Plasmodium falciparum and Plasmodium falciparum
    • Marfurt J., et al. Ex vivo drug susceptibility of ferroquine against chloroquine-resistant isolates of Plasmodium falciparum and Plasmodium falciparum. Antimicrob. Agents Chemother. 2011, 55:4461-4464.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 4461-4464
    • Marfurt, J.1
  • 49
    • 78649685500 scopus 로고    scopus 로고
    • In vitro activity of pyronaridine against multidrug resistant Plasmodium falciparum and Plasmodium falciparum
    • Price R.N., et al. In vitro activity of pyronaridine against multidrug resistant Plasmodium falciparum and Plasmodium falciparum. Antimicrob. Agents Chemother. 2010, 51:5146-5150.
    • (2010) Antimicrob. Agents Chemother. , vol.51 , pp. 5146-5150
    • Price, R.N.1
  • 50
    • 84866314696 scopus 로고    scopus 로고
    • Artemisinin-based combination therapy against Plasmodium falciparum: Comparative ex vivo activity of next-generation endoperoxides in multidrug resistant field isolates
    • Marfurt J., et al. Artemisinin-based combination therapy against Plasmodium falciparum: Comparative ex vivo activity of next-generation endoperoxides in multidrug resistant field isolates. Antimicrob. Agents Chemother. 2012, 10.1128/AAC.00283-12.
    • (2012) Antimicrob. Agents Chemother.
    • Marfurt, J.1
  • 51
    • 0035371224 scopus 로고    scopus 로고
    • Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria
    • Nomura T., et al. Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria. J. Infect. Dis. 2001, 183:1653-1661.
    • (2001) J. Infect. Dis. , vol.183 , pp. 1653-1661
    • Nomura, T.1
  • 52
    • 33750617911 scopus 로고    scopus 로고
    • Expression and function of pvcrt-o, a Plasmodium vivax ortholog of pfcrt, in Plasmodium falciparum and Dictyostelium discoideum
    • Sa J.M., et al. Expression and function of pvcrt-o, a Plasmodium vivax ortholog of pfcrt, in Plasmodium falciparum and Dictyostelium discoideum. Mol. Biochem. Parasitol. 2006, 150:219-228.
    • (2006) Mol. Biochem. Parasitol. , vol.150 , pp. 219-228
    • Sa, J.M.1
  • 53
    • 57049181505 scopus 로고    scopus 로고
    • Plasmodium vivax resistance to chloroquine in Madagascar: clinical efficacy and polymorphisms in pvmdr1 and pvcrt-o genes
    • Barnadas C., et al. Plasmodium vivax resistance to chloroquine in Madagascar: clinical efficacy and polymorphisms in pvmdr1 and pvcrt-o genes. Antimicrob. Agents Chemother. 2008, 52:4233-4240.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 4233-4240
    • Barnadas, C.1
  • 54
    • 65649098015 scopus 로고    scopus 로고
    • Increased expression levels of the pvcrt-o and pvmdr1 genes in a patient with severe Plasmodium vivax malaria
    • Fernandez-Becerra C., et al. Increased expression levels of the pvcrt-o and pvmdr1 genes in a patient with severe Plasmodium vivax malaria. Malar. J. 2009, 8:55.
    • (2009) Malar. J. , vol.8 , pp. 55
    • Fernandez-Becerra, C.1
  • 55
    • 48749090640 scopus 로고    scopus 로고
    • Molecular markers of in vivo Plasmodium vivax resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1
    • Marfurt J., et al. Molecular markers of in vivo Plasmodium vivax resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1. J. Infect. Dis. 2008, 198:409-417.
    • (2008) J. Infect. Dis. , vol.198 , pp. 409-417
    • Marfurt, J.1
  • 56
    • 14744302634 scopus 로고    scopus 로고
    • Plasmodium vivax: allele variants of the mdr1 gene do not associate with chloroquine resistance among isolates from Brazil, Papua, and monkey-adapted strains
    • Sa J.M., et al. Plasmodium vivax: allele variants of the mdr1 gene do not associate with chloroquine resistance among isolates from Brazil, Papua, and monkey-adapted strains. Exp. Parasitol. 2005, 109:256-259.
    • (2005) Exp. Parasitol. , vol.109 , pp. 256-259
    • Sa, J.M.1
  • 57
    • 79957971747 scopus 로고    scopus 로고
    • Therapeutic efficacy of chloroquine in Plasmodium vivax and the pvmdr1 polymorphisms in the Republic of Korea under mass chemoprophylaxis
    • Kim Y.K., et al. Therapeutic efficacy of chloroquine in Plasmodium vivax and the pvmdr1 polymorphisms in the Republic of Korea under mass chemoprophylaxis. Am. J. Trop. Med. Hyg. 2011, 84:532-534.
    • (2011) Am. J. Trop. Med. Hyg. , vol.84 , pp. 532-534
    • Kim, Y.K.1
  • 58
    • 46249096629 scopus 로고    scopus 로고
    • Gene amplification of Plasmodium vivax multidrug resistance 1 gene in Thailand, Laos, and Myanmar
    • Imwong M., et al. Gene amplification of Plasmodium vivax multidrug resistance 1 gene in Thailand, Laos, and Myanmar. Antimicrob. Agents Chemother. 2008, 52:2657-2659.
    • (2008) Antimicrob. Agents Chemother. , vol.52 , pp. 2657-2659
    • Imwong, M.1
  • 59
    • 33750619950 scopus 로고    scopus 로고
    • Amino acid mutations in Plasmodium vivax DHFR and DHPS from several geographical regions and susceptibility to antifolate drugs
    • Auliff A., et al. Amino acid mutations in Plasmodium vivax DHFR and DHPS from several geographical regions and susceptibility to antifolate drugs. Am. J. Trop. Med. Hyg. 2006, 75:617-621.
    • (2006) Am. J. Trop. Med. Hyg. , vol.75 , pp. 617-621
    • Auliff, A.1
  • 60
    • 12944316449 scopus 로고    scopus 로고
    • Novel Plasmodium vivax dhfr alleles from the Indonesian Archipelago and Papua New Guinea: association with pyrimethamine resistance determined by a Saccharomyces cerevisiae expression system
    • Hastings M.D., et al. Novel Plasmodium vivax dhfr alleles from the Indonesian Archipelago and Papua New Guinea: association with pyrimethamine resistance determined by a Saccharomyces cerevisiae expression system. Antimicrob. Agents Chemother. 2005, 49:733-740.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 733-740
    • Hastings, M.D.1
  • 61
    • 42949158717 scopus 로고    scopus 로고
    • Geographical distribution of amino acid mutations in Plasmodium vivax DHFR and DHPS from malaria endemic areas of Thailand
    • Rungsihirunrat K., et al. Geographical distribution of amino acid mutations in Plasmodium vivax DHFR and DHPS from malaria endemic areas of Thailand. Am. J. Trop. Med. Hyg. 2008, 78:462-467.
    • (2008) Am. J. Trop. Med. Hyg. , vol.78 , pp. 462-467
    • Rungsihirunrat, K.1
  • 62
    • 62149095320 scopus 로고    scopus 로고
    • Molecular characterization of antifolates resistance-associated genes, (dhfr and dhps) in Plasmodium vivax isolates from the Middle East
    • Zakeri S., et al. Molecular characterization of antifolates resistance-associated genes, (dhfr and dhps) in Plasmodium vivax isolates from the Middle East. Malar. J. 2009, 8:20.
    • (2009) Malar. J. , vol.8 , pp. 20
    • Zakeri, S.1
  • 63
    • 0036896964 scopus 로고    scopus 로고
    • Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations
    • Tjitra E., et al. Therapeutic efficacies of artesunate-sulfadoxine-pyrimethamine and chloroquine-sulfadoxine-pyrimethamine in vivax malaria pilot studies: relationship to Plasmodium vivax dhfr mutations. Antimicrob. Agents Chemother. 2002, 46:3947-3953.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 3947-3953
    • Tjitra, E.1
  • 64
    • 77956097961 scopus 로고    scopus 로고
    • Defining the role of mutations in Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene using an episomal Plasmodium falciparum transfection system
    • Auliff A.M., et al. Defining the role of mutations in Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene using an episomal Plasmodium falciparum transfection system. Antimicrob. Agents Chemother. 2010, 54:3927-3932.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 3927-3932
    • Auliff, A.M.1
  • 65
    • 34447651337 scopus 로고    scopus 로고
    • A novel Plasmodium falciparum expression system for assessing antifolate resistance caused by mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase
    • O'Neil M.T., et al. A novel Plasmodium falciparum expression system for assessing antifolate resistance caused by mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase. J. Infect. Dis. 2007, 196:467-474.
    • (2007) J. Infect. Dis. , vol.196 , pp. 467-474
    • O'Neil, M.T.1
  • 66
    • 84863624025 scopus 로고    scopus 로고
    • Functional analysis of Plasmodium vivax dihydrofolate reductase-thymidylate synthase genes through stable transformation of Plasmodium falciparum
    • Auliff A.M., et al. Functional analysis of Plasmodium vivax dihydrofolate reductase-thymidylate synthase genes through stable transformation of Plasmodium falciparum. PLoS ONE 2012, 7:e40416.
    • (2012) PLoS ONE , vol.7
    • Auliff, A.M.1
  • 67
    • 25844506182 scopus 로고    scopus 로고
    • Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand
    • Imwong M., et al. Limited polymorphism in the dihydropteroate synthetase gene (dhps) of Plasmodium vivax isolates from Thailand. Antimicrob. Agents Chemother. 2005, 49:4393-4395.
    • (2005) Antimicrob. Agents Chemother. , vol.49 , pp. 4393-4395
    • Imwong, M.1
  • 68
    • 33846795683 scopus 로고    scopus 로고
    • Linkage Group Selection - a fast approach to the genetic analysis of malaria parasites
    • Carter R., et al. Linkage Group Selection - a fast approach to the genetic analysis of malaria parasites. Int. J. Parasitol. 2007, 37:285-293.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 285-293
    • Carter, R.1
  • 69
    • 77956563692 scopus 로고    scopus 로고
    • Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites
    • Hunt P., et al. Experimental evolution, genetic analysis and genome re-sequencing reveal the mutation conferring artemisinin resistance in an isogenic lineage of malaria parasites. BMC Genomics 2010, 11:499.
    • (2010) BMC Genomics , vol.11 , pp. 499
    • Hunt, P.1
  • 70
    • 79960572208 scopus 로고    scopus 로고
    • An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing
    • Auburn S., et al. An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing. PLoS ONE 2011, 6:e22213.
    • (2011) PLoS ONE , vol.6
    • Auburn, S.1
  • 71
    • 77953665105 scopus 로고    scopus 로고
    • Recent progress in functional genomic research in Plasmodium falciparum
    • Mu J., et al. Recent progress in functional genomic research in Plasmodium falciparum. Curr. Genomics 2010, 11:279-286.
    • (2010) Curr. Genomics , vol.11 , pp. 279-286
    • Mu, J.1
  • 72
    • 84864655057 scopus 로고    scopus 로고
    • Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite
    • Park D.J., et al. Sequence-based association and selection scans identify drug resistance loci in the Plasmodium falciparum malaria parasite. Proc. Natl. Acad. Sci. U.S.A. 2012, 109:13052-13057.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109 , pp. 13052-13057
    • Park, D.J.1
  • 73
    • 79955632728 scopus 로고    scopus 로고
    • Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum
    • Van Tyne D., et al. Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. PLoS Genet. 2011, 7:e1001383.
    • (2011) PLoS Genet. , vol.7
    • Van Tyne, D.1
  • 74
    • 0037167852 scopus 로고    scopus 로고
    • Detecting recent positive selection in the human genome from haplotype structure
    • Sabeti P.C., et al. Detecting recent positive selection in the human genome from haplotype structure. Nature 2002, 419:832-837.
    • (2002) Nature , vol.419 , pp. 832-837
    • Sabeti, P.C.1
  • 75
    • 84867761314 scopus 로고    scopus 로고
    • SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum Malaria Parasites
    • Amambua-Ngwa A., et al. SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum Malaria Parasites. Mol. Biol. Evol. 2012, 10.1093/molbev/mss151.
    • (2012) Mol. Biol. Evol.
    • Amambua-Ngwa, A.1
  • 76
    • 35349012592 scopus 로고    scopus 로고
    • Genome-wide detection and characterization of positive selection in human populations
    • Sabeti P.C., et al. Genome-wide detection and characterization of positive selection in human populations. Nature 2007, 449:913-918.
    • (2007) Nature , vol.449 , pp. 913-918
    • Sabeti, P.C.1
  • 77
    • 78650552144 scopus 로고    scopus 로고
    • Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes
    • Dharia N.V., et al. Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:20045-20050.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 20045-20050
    • Dharia, N.V.1
  • 78
    • 67650658803 scopus 로고    scopus 로고
    • Effective and cheap removal of leukocytes and platelets from Plasmodium vivax infected blood
    • Sriprawat K., et al. Effective and cheap removal of leukocytes and platelets from Plasmodium vivax infected blood. Malar. J. 2009, 8:115.
    • (2009) Malar. J. , vol.8 , pp. 115
    • Sriprawat, K.1
  • 79
    • 84862492581 scopus 로고    scopus 로고
    • Whole genome sequencing analysis of Plasmodium vivax using whole genome capture
    • Bright A.T., et al. Whole genome sequencing analysis of Plasmodium vivax using whole genome capture. BMC Genomics 2012, 13:262.
    • (2012) BMC Genomics , vol.13 , pp. 262
    • Bright, A.T.1
  • 80
    • 84863982076 scopus 로고    scopus 로고
    • Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
    • Manske M., et al. Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing. Nature 2012, 10.1038/nature11174.
    • (2012) Nature
    • Manske, M.1
  • 81
    • 53649104458 scopus 로고    scopus 로고
    • Comparative genomics of the neglected human malaria parasite Plasmodium vivax
    • Carlton J.M., et al. Comparative genomics of the neglected human malaria parasite Plasmodium vivax. Nature 2008, 455:757-763.
    • (2008) Nature , vol.455 , pp. 757-763
    • Carlton, J.M.1
  • 82
    • 84865681782 scopus 로고    scopus 로고
    • The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum
    • Neafsey D.E., et al. The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum. Nat. Genet. 2012, 10.1038/ng.2373.
    • (2012) Nat. Genet.
    • Neafsey, D.E.1
  • 83
    • 34047213680 scopus 로고    scopus 로고
    • Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia
    • Ferreira M.U., et al. Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia. J. Infect. Dis. 2007, 195:1218-1226.
    • (2007) J. Infect. Dis. , vol.195 , pp. 1218-1226
    • Ferreira, M.U.1
  • 84
    • 40649121266 scopus 로고    scopus 로고
    • Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax
    • Karunaweera N.D., et al. Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax. Gene 2008, 410:105-112.
    • (2008) Gene , vol.410 , pp. 105-112
    • Karunaweera, N.D.1
  • 85
    • 77954623570 scopus 로고    scopus 로고
    • Single-nucleotide polymorphism, linkage disequilibrium and geographic structure in the malaria parasite Plasmodium vivax: prospects for genome-wide association studies
    • Orjuela-Sanchez P., et al. Single-nucleotide polymorphism, linkage disequilibrium and geographic structure in the malaria parasite Plasmodium vivax: prospects for genome-wide association studies. BMC Genet. 2010, 11:65.
    • (2010) BMC Genet. , vol.11 , pp. 65
    • Orjuela-Sanchez, P.1
  • 86
    • 35649027303 scopus 로고    scopus 로고
    • Neglect of Plasmodium vivax malaria
    • Baird J.K. Neglect of Plasmodium vivax malaria. Trends Parasitol. 2007, 23:533-539.
    • (2007) Trends Parasitol. , vol.23 , pp. 533-539
    • Baird, J.K.1
  • 87
    • 68949106269 scopus 로고    scopus 로고
    • Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite
    • Mueller I., et al. Key gaps in the knowledge of Plasmodium vivax, a neglected human malaria parasite. Lancet Infect. Dis. 2009, 9:555-566.
    • (2009) Lancet Infect. Dis. , vol.9 , pp. 555-566
    • Mueller, I.1
  • 88
    • 11844274676 scopus 로고    scopus 로고
    • Identification of the Plasmodium vivax mdr-like gene (pvmdr1) and analysis of single-nucleotide polymorphisms among isolates from different areas of endemicity
    • Brega S., et al. Identification of the Plasmodium vivax mdr-like gene (pvmdr1) and analysis of single-nucleotide polymorphisms among isolates from different areas of endemicity. J. Infect. Dis. 2005, 191:272-277.
    • (2005) J. Infect. Dis. , vol.191 , pp. 272-277
    • Brega, S.1
  • 89
    • 2542506444 scopus 로고    scopus 로고
    • Sulfadoxine resistance in Plasmodium vivax is associated with a specific amino acid in dihydropteroate synthase at the putative sulfadoxine-binding site
    • Korsinczky M., et al. Sulfadoxine resistance in Plasmodium vivax is associated with a specific amino acid in dihydropteroate synthase at the putative sulfadoxine-binding site. Antimicrob. Agents Chemother. 2004, 48:2214-2222.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , pp. 2214-2222
    • Korsinczky, M.1
  • 90
    • 78650647223 scopus 로고    scopus 로고
    • In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia
    • Siswantoro H., et al. In vivo and in vitro efficacy of chloroquine against Plasmodium malariae and P. ovale in Papua, Indonesia. Antimicrob. Agents Chemother. 2011, 55:197-202.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 197-202
    • Siswantoro, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.