The influence of gastric emptying kinetics on the drug release from enteric coated pellets in fasted state: An in vitro/in vivo correlation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 82, Issue 2, 2012, Pages 376-382

  Stefanic M ^a   Locatelli, I ^b   Vrecer F ^a,b   Sever, T ^a   Mrhar, A ^b   Bogataj, M ^b  

^a KRKA D D   (Slovenia)

^b UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Enteric coated pellets; Gastric emptying; In vitro dissolution; In vivo dissolution prediction; IVIVC; Multiparticulate systems

Indexed keywords

LANSOPRAZOLE;

ARTICLE; DRUG ABSORPTION; DRUG DEGRADATION; DRUG RELEASE; DRUG SOLUBILITY; ENTERIC COATED TABLET; IN VITRO STUDY; IN VIVO STUDY; KINETICS; MATHEMATICAL MODEL; MEAN RESIDENCE TIME; STOMACH EMPTYING; TABLET FORMULATION;

BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; GASTRIC EMPTYING; HUMANS; HYDROGEN-ION CONCENTRATION; INTESTINAL ABSORPTION; INTESTINE, SMALL; KINETICS; MODELS, BIOLOGICAL; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; SOLUBILITY; TABLETS;

EID: 84867860406     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2012.07.011     Document Type: Article

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