Discovery of small molecules that inhibit melanogenesis via regulation of tyrosinase expression

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 22, 2012, Pages 6943-6946

  Song, Jiho ^a   Lee, Hyun E ^b   Kim, Young Jin ^a   Kim, Su Yeon ^b   Kim, Dong Seok ^b   Min, Kyung Hoon ^a  

^a Chung Ang University   (South Korea)

^b Chung Ang University College of Medicine   (South Korea)

Author keywords

Isoxazole; Melanogenesis; Small molecule; Tyrosinase

Indexed keywords

5,6,7,8 TETRAHYDRO 4H CYCLOHEPTA [D] ISOXAZOLE DERIVATIVE; ALPHA INTERMEDIN; ENZYME INHIBITOR; KOJIC ACID; MONOPHENOL MONOOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DOWN REGULATION; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; IN VITRO STUDY; MELANOGENESIS; MELANOMA CELL; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION; WESTERN BLOTTING;

ALPHA-MSH; ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CYCLOHEPTANES; DOWN-REGULATION; DRUG EVALUATION, PRECLINICAL; ISOXAZOLES; MICE; MONOPHENOL MONOOXYGENASE; PIPERAZINES; PYRONES;

EID: 84867855807     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.09.003     Document Type: Article

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