A randomized phase II trial of intra-arterial chemotherapy using SM-11355 (Miriplatin) for hepatocellular carcinoma

Investigational New Drugs

Volumn 30, Issue 5, 2012, Pages 2015-2025

  Okusaka, Takuji ^a   Kasugai, Hiroshi ^b   Ishii, Hiroshi ^c   Kudo, Masatoshi ^d   Sata, Michio ^e   Tanaka, Katsuaki ^f   Shioyama, Yasukazu ^g   Chayama, Kazuaki ^h   Kumada, Hiromitsu ⁱ   Yoshikawa, Masaharu ^j   Seki, Toshihito ^k   Saito, Hidetugu ^l   Hayashi, Naoaki ^m   Shiratori, Keiko ^m   Okita, Kiwamu ⁿ   Sakaida, Isao ⁿ   Honda, Masao ^o   Kusumoto, Yukio ^p   Tsutsumi, Takuya ^p   Sakata, Kenji ^q  

^a NATIONAL CANCER CENTER HOSPITAL   (Japan)

^b OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^c CANCER INSTITUTE HOSPITAL   (Japan)

^d KINKI UNIVERSITY   (Japan)

^e KURUME UNIVERSITY   (Japan)

^f YOKOHAMA CITY UNIVERSITY HOSPITAL   (Japan)

^g DOKKYO MEDICAL UNIVERSITY   (Japan)

^h HIROSHIMA UNIVERSITY   (Japan)

ⁱ TORANOMON HOSPITAL   (Japan)

^j CHIBA UNIVERSITY   (Japan)

^k KANSAI MEDICAL UNIVERSITY   (Japan)

^l KEIO UNIVERSITY HOSPITAL   (Japan)

^m TOKYO WOMEN S MEDICAL UNIVERSITY MEDICAL CENTER EAST   (Japan)

ⁿ YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^o KANAZAWA UNIVERSITY   (Japan)

^p Nagasaki Municipal Hospital   (Japan)

^q Department of Anesthesiology   (Japan)

more..

Author keywords

Iodized oil; Liver cancer; MIRIPLA; Parallel study; Suspension

Indexed keywords

ALPHA FETOPROTEIN; IODINATED POPPYSEED OIL; MIRIPLATIN; ZINOSTATIN MALEIC ACID STYRENE COPOLYMER;

ABDOMINAL PAIN; ACUTE HEART INFARCTION; ADULT; AGED; ANTINEOPLASTIC ACTIVITY; ARTICLE; BILE DUCT DILATATION; BILE DUCT DISEASE; BLOOD SAMPLING; CANCER GROWTH; CANCER RECURRENCE; CANCER SURVIVAL; CHEMOEMBOLIZATION; CHILL; CHOLESTASIS; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CREATININE URINE LEVEL; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG FEVER; DRUG SAFETY; DRUG STRUCTURE; EOSINOPHIL; EOSINOPHILIA; ESOPHAGUS VARICES BLEEDING; FATIGUE; FEMALE; GLUCOSE BLOOD LEVEL; HEART INFARCTION; HEPATOBILIARY DISEASE; HUMAN; HYPERBILIRUBINEMIA; HYPERGLYCEMIA; HYPOTENSION; INJECTION SITE PAIN; INOPERABLE CANCER; LEUKOCYTE; LEUKOPENIA; LIVER ATROPHY; LIVER CELL CARCINOMA; LIVER DYSFUNCTION; LIVER FAILURE; LIVER INJURY; LYMPHOCYTE; MAJOR CLINICAL STUDY; MALE; MONOCYTE; MULTICENTER STUDY; NEUTROPENIA; NEUTROPHIL; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROTHROMBIN TIME; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY DISTRESS; SEPSIS; SIDE EFFECT; SURVIVAL TIME; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THROMBOCYTE; THROMBOCYTOPENIA; TUMOR VOLUME; VOMITING;

AGED; CARCINOMA, HEPATOCELLULAR; DRUG ADMINISTRATION SCHEDULE; FEMALE; HEPATIC ARTERY; HUMANS; INFUSIONS, INTRA-ARTERIAL; LIVER NEOPLASMS; MALE; MIDDLE AGED; ORGANOPLATINUM COMPOUNDS; SURVIVAL RATE;

EID: 84867849811     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-011-9776-4     Document Type: Article

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