A method for detecting covalent modification of sensor proteins associated with 1,4-naphthoquinone-induced activation of electrophilic signal transduction pathways

Journal of Toxicological Sciences

Volumn 37, Issue 5, 2012, Pages 891-898

  Hirose, Reiko ^a   Miura, Takashi ^b   Sha, Ryo ^b   Shinkai, Yasuhiro ^a,b   Tanaka Kagawa, Toshiko ^c   Kumagai, Yoshito ^a,b  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TSUKUBA   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

1,4 Naphthoquinone; Covalent modification; Electrophilic signal transduction; Immunochemical detection; Naphthalene

Indexed keywords

1,4 NAPHTHOQUINONE; CARBONYL DERIVATIVE; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 90; HEAT SHOCK TRANSCRIPTION FACTOR 1; NAPHTHALENE; POLYCLONAL ANTIBODY; QUINONE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; COVALENT BOND; CROSS REACTION; DOT HYBRIDIZATION; ELECTROPHILICITY; FEMALE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; ISOTOPE LABELING; MASS SPECTROMETRY; MOLECULAR SENSOR; NONHUMAN; PROTEIN MODIFICATION; PROTEIN TARGETING; SIGNAL TRANSDUCTION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84867844916     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.37.891     Document Type: Article

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