Preventing protein adsorption and macrophage uptake of gold nanoparticles via a hydrophobic shield

ACS Nano

Volumn 6, Issue 10, 2012, Pages 9182-9190

  Larson, Timothy A ^a   Joshi, Pratixa P ^a   Sokolov, Konstantin ^a,b  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

cellular interaction; gold nanoparticles; polyethylene glycol; protein adsorption

Indexed keywords

ALKYL LINKERS; BIOLOGICAL APPLICATIONS; CELL UPTAKE; CELLULAR INTERACTION; GOLD NANOPARTICLE; GOLD NANOPARTICLES; GOLD SURFACES; NON-SPECIFIC INTERACTIONS; PHYSIOLOGICAL CONCENTRATIONS; PROTEIN ADSORPTION; SHIELD LAYERS; STEALTH PROPERTY; SURFACE COATINGS;

AMINO ACIDS; COATINGS; HYDROPHOBICITY; MACROPHAGES; METAL NANOPARTICLES; MOTION PICTURE EXPERTS GROUP STANDARDS; POLYETHYLENE GLYCOLS;

GOLD;

BIOMATERIAL; GOLD; MACROGOL DERIVATIVE; METAL NANOPARTICLE;

ADSORPTION; ANIMAL; ARTICLE; CELL CULTURE; CHEMICAL PHENOMENA; CHEMISTRY; DIFFUSION; MACROPHAGE; MATERIALS TESTING; MOUSE; ULTRASTRUCTURE;

ADSORPTION; ANIMALS; CELLS, CULTURED; COATED MATERIALS, BIOCOMPATIBLE; DIFFUSION; GOLD; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MACROPHAGES; MATERIALS TESTING; METAL NANOPARTICLES; MICE; POLYETHYLENE GLYCOLS;

EID: 84867800614     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn3035155     Document Type: Article

References (71)

1. Ghosh, P.; Han, G.; De, M.; Kim, C. K.; Rotello, V. M. Gold Nanoparticles in Delivery Applications Adv. Drug Delivery Rev. 2008, 60, 1307-1315
2. Huang, X.; Jain, P. K.; El-Sayed, I. H.; El-Sayed, M. A. Gold Nanoparticles: Interesting Optical Properties and Recent Applications in Cancer Diagnostics and Therapy Nanomedicine 2007, 2, 681-693 (Pubitemid 350268247)
3. Sokolov, K.; Follen, M.; Aaron, J.; Pavlova, I.; Malpica, A.; Lotan, R.; Richards-Kortum, R. Real-Time Vital Optical Imaging of Precancer Using Anti-Epidermal Growth Factor Receptor Antibodies Conjugated to Gold Nanoparticles Cancer Res. 2003, 63, 1999-2004 (Pubitemid 36538596)
4. Skala, M. C.; Crow, M. J.; Wax, A.; Izatt, J. A. Photothermal Optical Coherence Tomography of Epidermal Growth Factor Receptor in Live Cells Using Immunotargeted Gold Nanospheres Nano Lett. 2008, 8, 3461-3467
5. Rana, S.; Bajaj, A.; Mout, R.; Rotello, V. M. Monolayer Coated Gold Nanoparticles for Delivery Applications Adv. Drug Delivery Rev. 2012, 64, 200-216
6. Mallidi, S.; Larson, T.; Aaron, J.; Sokolov, K.; Emelianov, S. Molecular Specific Optoacoustic Imaging with Plasmonic Nanoparticles Opt. Express 2007, 15, 6583-6588 (Pubitemid 46827656)
7. Li, W.; Cai, X.; Kim, C.; Sun, G.; Zhang, Y.; Deng, R.; Yang, M.; Chen, J.; Achilefu, S.; Wang, L. V. et al. Gold Nanocages Covered with Thermally-Responsive Polymers for Controlled Release by High-Intensity Focused Ultrasound Nanoscale 2011, 3, 1724-1730
8. Dykman, L.; Khlebtsov, N. Gold Nanoparticles in Biomedical Applications: Recent Advances and Perspectives Chem. Soc. Rev. 2012, 41, 2256-2282
9. Dreaden, E. C.; Austin, L. A.; Mackey, M. A.; El-Sayed, M. A. Size Matters: Gold Nanoparticles in Targeted Cancer Drug Delivery Ther. Delivery 2012, 3, 457-478
10. Curry, A.; Crow, M. J.; Wax, A. Molecular Imaging of Epidermal Growth Factor Receptor in Live Cells with Refractive Index Sensitivity Using Dark-Field Microspectroscopy and Immunotargeted Nanoparticles J. Biomed. Opt. 2008, 13, 014022/1-014022/7
11. Chanda, N.; Kattumuri, V.; Shukla, R.; Zambre, A.; Katti, K.; Upendran, A.; Kulkarni, R. R.; Kan, P.; Fent, G. M.; Casteel, S. W. et al. Bombesin Functionalized Gold Nanoparticles Show in Vitro and in Vivo Cancer Receptor Specificity Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 8760-8765
12. Aaron, J.; Nitin, N.; Travis, K.; Kumar, S.; Collier, T.; Park, S. Y.; Jose-Yacaman, M.; Coghlan, L.; Follen, M.; Richards-Kortum, R. et al. Plasmon Resonance Coupling of Metal Nanoparticles for Molecular Imaging of Carcinogenesis in Vivo J. Biomed. Opt. 2007, 12, 034007/1-034007/11
13. Tkachenko, A. G.; Xie, H.; Coleman, D.; Glomm, W.; Ryan, J.; Anderson, M. F.; Franzen, S.; Feldheim, D. L. Multifunctional Gold Nanoparticle-Peptide Complexes for Nuclear Targeting J. Am. Chem. Soc. 2003, 125, 4700-4701 (Pubitemid 36505350)
14. Kim, D.; Jeong, Y. Y.; Jon, S. A Drug-Loaded Aptamer-Gold Nanoparticle Bioconjugate for Combined CT Imaging and Therapy of Prostate Cancer ACS Nano 2010, 4, 3689-3696
15. Jain, P. K.; Lee, K. S.; El-Sayed, I. H.; El-Sayed, M. A. Calculated Absorption and Scattering Properties of Gold Nanoparticles of Different Size, Shape, and Composition: Applications in Biological Imaging and Biomedicine J. Phys. Chem. B 2006, 110, 7238-7248
16. Seekell, K.; Crow, M. J.; Marinakos, S.; Ostrander, J.; Chilkoti, A.; Wax, A. Hyperspectral Molecular Imaging of Multiple Receptors Using Immunolabeled Plasmonic Nanoparticles J. Biomed. Opt. 2011, 16, 116003/116001-116003/116012
17. Young, J. K.; Figueroa, E. R.; Drezek, R. A. Tunable Nanostructures as Photothermal Theranostic Agents Ann. Biomed. Eng. 2012, 40, 438-459
18. Albanese, A.; Chan, W. C. W. Effect of Gold Nanoparticle Aggregation on Cell Uptake and Toxicity ACS Nano 2011, 5, 5478-5489
19. Corbierre, M. K.; Cameron, N. S.; Sutton, M.; Mochrie, S. G. J.; Lurio, L. B.; Rühm, A.; Lennox, R. B. Polymer-Stabilized Gold Nanoparticles and Their Incorporation into Polymer Matrices J. Am. Chem. Soc. 2001, 123, 10411-10412 (Pubitemid 32979800)
20. Zhao, W.; Brook, M. A.; Li, Y. Design of Gold Nanoparticle-Based Colorimetric Biosensing Assays ChemBioChem 2008, 9, 2363-2371
21. Krpetić, Z. e.; Nativo, P.; Porta, F.; Brust, M. A Multidentate Peptide for Stabilization and Facile Bioconjugation of Gold Nanoparticles Bioconjugate Chem. 2009, 20, 619-624
22. Kumar, S.; Aaron, J.; Sokolov, K. V. Directional Conjugation of Antibodies to Nanoparticles for Synthesis of Multiplexed Optical Contrast Agents with Both Delivery and Targeting Moieties Nat. Protoc. 2008, 3, 314-320 (Pubitemid 351266515)
23. Nune, S. K.; Chanda, N.; Shukla, R.; Katti, K.; Kulkarni, R. R.; Thilakavathy, S.; Mekapothula, S.; Kannan, R.; Katti, K. V. Green Nanotechnology from Tea: Phytochemicals in Tea as Building Blocks for Production of Biocompatible Gold Nanoparticles J. Mater. Chem. 2009, 19, 2912-2920
24. Tam, N. C. M.; Scott, B. M. T.; Voicu, D.; Wilson, B. C.; Zheng, G. Facile Synthesis of Raman Active Phospholipid Gold Nanoparticles Bioconjugate Chem. 2010, 21, 2178-2182
25. Shon, Y.-S.; Mazzitelli, C.; Murray, R. W. Unsymmetrical Disulfides and Thiol Mixtures Produce Different Mixed Monolayer-Protected Gold Clusters Langmuir 2001, 17, 7735-7741 (Pubitemid 35330941)
26. Eck, W.; Craig, G.; Sigdel, A.; Ritter, G.; Old, L. J.; Tang, L.; Brennan, M. F.; Allen, P. J.; Mason, M. D. Pegylated Gold Nanoparticles Conjugated to Monoclonal F19 Antibodies as Targeted Labeling Agents for Human Pancreatic Carcinoma Tissue ACS Nano 2008, 2, 2263-2272
27. Knop, K.; Hoogenboom, R.; Fischer, D.; Schubert, U. S. Poly(Ethylene Glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives Angew. Chem., Int. Ed.. 2010, 49, 6288-6308
28. Arnida; Malugin, A.; Ghandehari, H. Cellular Uptake and Toxicity of Gold Nanoparticles in Prostate Cancer Cells: A Comparative Study of Rods and Spheres J. Appl. Toxicol. 2010, 30, 212-217
29. Walkey, C. D.; Olsen, J. B.; Guo, H.; Emili, A.; Chan, W. C. W. Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake J. Am. Chem. Soc. 2011, 134, 2139-2147
30. Larson, T.; Bankson, J. A.; Aaron, J.; Sokolov, K. Hybrid Plasmonic Magnetic Nanoparticles as Molecular Specific Agents for Mri/Optical Imaging and Photothermal Therapy of Cancer Cells Nanotechnology 2007, 18, 325101/1-325101/8
31. Mallidi, S.; Larson, T.; Tam, J.; Joshi, P. P.; Karpiouk, A.; Sokolov, K.; Emelianov, S. Multiwavelength Photoacoustic Imaging and Plasmon Resonance Coupling of Gold Nanoparticles for Selective Detection of Cancer Nano Lett. 2009, 9, 2825-2831
32. Walkey, C. D.; Chan, W. C. W. Understanding and Controlling the Interaction of Nanomaterials with Proteins in a Physiological Environment Chem. Soc. Rev. 2012, 41, 2780-2799
33. Perrault, S. D.; Walkey, C.; Jennings, T.; Fischer, H. C.; Chan, W. C. W. Mediating Tumor Targeting Efficiency of Nanoparticles through Design Nano Lett. 2009, 9, 1909-1915
34. Brannon-Peppas, L.; Blanchette, J. O. Nanoparticle and Targeted Systems for Cancer Therapy Adv. Drug Delivery Rev. 2004, 56, 1649-1659 (Pubitemid 39177694)
35. Choi, C. H. J.; Alabi, C. A.; Webster, P.; Davis, M. E. Mechanism of Active Targeting in Solid Tumors with Transferrin-Containing Gold Nanoparticles Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 1235-1240
36. Soo Choi, H.; Liu, W.; Misra, P.; Tanaka, E.; Zimmer, J. P.; Itty Ipe, B.; Bawendi, M. G.; Frangioni, J. V. Renal Clearance of Quantum Dots Nat. Biotechnol. 2007, 25, 1165-1170 (Pubitemid 47538116)
37. Hirsch, L. R.; Stafford, R. J.; Bankson, J. A.; Sershen, S. R.; Rivera, B.; Price, R. E.; Hazle, J. D.; Halas, N. J.; West, J. L. Nanoshell-Mediated Near-Infrared Thermal Therapy of Tumors under Magnetic Resonance Guidance Proc. Natl. Acad. Sci. U.S.A. 2003, 100, 13549-13554 (Pubitemid 37444779)
38. Niidome, T.; Yamagata, M.; Okamoto, Y.; Akiyama, Y.; Takahashi, H.; Kawano, T.; Katayama, Y.; Niidome, Y. Peg-Modified Gold Nanorods with a Stealth Character for in Vivo Applications J. Controlled Release 2006, 114, 343-347 (Pubitemid 44310822)
39. Akiyama, Y.; Mori, T.; Katayama, Y.; Niidome, T. The Effects of Peg Grafting Level and Injection Dose on Gold Nanorod Biodistribution in the Tumor-Bearing Mice J. Controlled Release 2009, 139, 81-84
40. von Maltzahn, G.; Park, J.-H.; Agrawal, A.; Bandaru, N. K.; Das, S. K.; Sailor, M. J.; Bhatia, S. N. Computationally Guided Photothermal Tumor Therapy Using Long-Circulating Gold Nanorod Antennas Cancer Res. 2009, 69, 3892-3900
41. Paciotti, G. F.; Myer, L.; Weinreich, D.; Goia, D.; Pavel, N.; McLaughlin, R. E.; Tamarkin, L. Colloidal Gold: A Novel Nanoparticle Vector for Tumor Directed Drug Delivery Drug Delivery 2004, 11, 169-183 (Pubitemid 38720414)
42. Lipka, J.; Semmler-Behnke, M.; Sperling, R. A.; Wenk, A.; Takenaka, S.; Schleh, C.; Kissel, T.; Parak, W. J.; Kreyling, W. G. Biodistribution of Peg-Modified Gold Nanoparticles Following Intratracheal Instillation and Intravenous Injection Biomaterials 2010, 31, 6574-6581
43. Oishi, M.; Nakaogami, J.; Ishii, T.; Nagasaki, Y. Smart Pegylated Gold Nanoparticles for the Cytoplasmic Delivery of siRNA to Induce Enhanced Gene Silencing Chem. Lett. 2006, 35, 1046-1047 (Pubitemid 44859908)
44. Li, N.; Larson, T.; Nguyen, H. H.; Sokolov, K. V.; Ellington, A. D. Directed Evolution of Gold Nanoparticle Delivery to Cells Chem. Commun. (Cambridge, U. K.) 2010, 46, 392-394
45. Sato, K.; Hosokawa, K.; Maeda, M. Non-Cross-Linking Gold Nanoparticle Aggregation as a Detection Method for Single-Base Substitutions Nucleic Acids Res. 2005, 33, e4
46. Dröge, W.; Eck, H. P.; Gmünder, H.; Mihm, S. Modulation of Lymphocyte Functions and Immune Responses by Cysteine and Cysteine Derivatives Am. J. Med. 1991, 91, S140-S144
47. Gmunder, H.; Eck, H. P.; Benninghoff, B.; Roth, S.; Droge, W. Macrophages Regulate Intracellular Glutathione Levels of Lymphocytes. Evidence for an Immunoregulatory Role of Cysteine Cell. Immunol. 1990, 129, 32-46 (Pubitemid 20233611)
48. Jacob, N.; Bruckert, E.; Giral, P.; Foglietti, M. J.; Turpin, G. Cysteine Is a Cardiovascular Risk Factor in Hyperlipidemic Patients Atherosclerosis 1999, 146, 53-59 (Pubitemid 29371861)
49. Muller, F.; Svardal, A.; Aukrust, P.; Berge, R.; Ueland, P.; Froland, S. Elevated Plasma Concentration of Reduced Homocysteine in Patients with Human Immunodeficiency Virus Infection Am. J. Clin. Nutr. 1996, 63, 242-248 (Pubitemid 26036246)
50. Murphy, G.; Fan, J.-H.; Mark, S. D.; Dawsey, S. M.; Selhub, J.; Wang, J.; Taylor, P. R.; Qiao, Y.-L.; Abnet, C. C. Prospective Study of Serum Cysteine Levels and Oesophageal and Gastric Cancers in China Gut 2011, 60, 618-623
51. Özkan, Y.; Özkan, E.; Şimşek, B. Plasma Total Homocysteine and Cysteine Levels as Cardiovascular Risk Factors in Coronary Heart Disease Int. J. Cardiol. 2002, 82, 269-277 (Pubitemid 34241583)
52. Turkevich, J.; Stevenson, P. C.; Hillier, J. The Formation of Colloidal Gold J. Phys. Chem. 1953, 57, 670-673
53. Ji, X.; Song, X.; Li, J.; Bai, Y.; Yang, W.; Peng, X. Size Control of Gold Nanocrystals in Citrate Reduction: The Third Role of Citrate J. Am. Chem. Soc. 2007, 129, 13939-13948 (Pubitemid 350106084)
54. Ojea-Jiménez, I.; Bastús, N. G.; Puntes, V. Influence of the Sequence of the Reagents Addition in the Citrate-Mediated Synthesis of Gold Nanoparticles J. Phys. Chem. C 2011, 115, 15752-15757
55. Frens, G. Controlled Nucleation for the Regulation of the Particle Size in Monodisperse Colloid Suspensions Nature 1973, 241, 20-22
56. Zheng, D.; Seferos, D. S.; Giljohann, D. A.; Patel, P. C.; Mirkin, C. A. Aptamer Nano-flares for Molecular Detection in Living Cells Nano Lett. 2009, 9, 3258-3261
57. Schneider, G.; Decher, G.; Nerambourg, N.; Praho, R.; Werts, M. H. V.; Blanchard-Desce, M. Distance-Dependent Fluorescence Quenching on Gold Nanoparticles Ensheathed with Layer-by-Layer Assembled Polyelectrolytes Nano Lett. 2006, 6, 530-536
58. Yi, D. K.; Sun, I.-C.; Ryu, J. H.; Koo, H.; Park, C. W.; Youn, I.-C.; Choi, K.; Kwon, I. C.; Kim, K.; Ahn, C.-H. Matrix Metalloproteinase Sensitive Gold Nanorod for Simultaneous Bioimaging and Photothermal Therapy of Cancer Bioconjugate Chem. 2010, 21, 2173-2177
59. Lee, S.; Cha, E.-J.; Park, K.; Lee, S.-Y.; Hong, J.-K.; Sun, I.-C.; Kim, S. Y.; Choi, K.; Kwon, I. C.; Kim, K. et al. A Near-Infrared-Fluorescence- Quenched Gold-Nanoparticle Imaging Probe for in Vivo Drug Screening and Protease Activity Determination Angew. Chem. 2008, 120, 2846-2849
60. Grönbeck, H.; Curioni, A.; Andreoni, W. Thiols and Disulfides on the Au(111) Surface: The Headgroup-Gold Interaction J. Am. Chem. Soc. 2000, 122, 3839-3842 (Pubitemid 30241585)
61. Reyes, E. n.; Madueño, R.; Blázquez, M.; Pineda, T. Facile Exchange of Ligands on the 6-Mercaptopurine-Monolayer Protected Gold Clusters Surface J. Phys. Chem. C 2010, 114, 15955-15962
62. Caragheorgheopol, A.; Chechik, V. Mechanistic Aspects of Ligand Exchange in Au Nanoparticles Phys. Chem. Chem. Phys. 2008, 10, 5029-5041
63. Maus, L.; Dick, O.; Bading, H.; Spatz, J. P.; Fiammengo, R. Conjugation of Peptides to the Passivation Shell of Gold Nanoparticles for Targeting of Cell-Surface Receptors ACS Nano 2010, 4, 6617-6628
64. Marazzi, J.; Kleyer, J.; Paredes, J. M. V.; Gertsch, J. Endocannabinoid Content in Fetal Bovine Sera-Unexpected Effects on Mononuclear Cells and Osteoclastogenesis J. Immunol. Methods 2011, 373, 219-228
65. Lundqvist, M.; Stigler, J.; Cedervall, T.; Berggård, T.; Flanagan, M. B.; Lynch, I.; Elia, G.; Dawson, K. The Evolution of the Protein Corona around Nanoparticles: A Test Study ACS Nano 2011, 5, 7503-7509
66. Casals, E.; Pfaller, T.; Duschl, A.; Oostingh, G. J.; Puntes, V. Time Evolution of the Nanoparticle Protein Corona ACS Nano 2010, 4, 3623-3632
67. Doty, R. C.; Tshikhudo, T. R.; Brust, M.; Fernig, D. G. Extremely Stable Water-Soluble Ag Nanoparticles Chem. Mater. 2005, 17, 4630-4635 (Pubitemid 41362492)
68. Read, S. M.; Northcote, D. H. Minimization of Variation in the Response to Different Proteins of the Coomassie Blue G Dye-Binding Assay for Protein Anal. Biochem. 1981, 116, 53-64 (Pubitemid 12176725)
69. Mosmann, T. Rapid Colorimetric Assay for Cellular Growth and Survival: Application to Proliferation and Cytotoxicity Assays J. Immunol. Methods 1983, 65, 55-63 (Pubitemid 14203433)
70. Ralph, P.; Moore, M. A.; Nilsson, K. Lysozyme Synthesis by Established Human and Murine Histiocytic Lymphoma Cell Lines J. Exp. Med. 1976, 143, 1528-1533
71. Zhang, D.; Neumann, O.; Wang, H.; Yuwono, V. M.; Barhoumi, A.; Perham, M.; Hartgerink, J. D.; Wittung-Stafshede, P.; Halas, N. J. Gold Nanoparticles Can Induce the Formation of Protein-Based Aggregates at Physiological pH Nano Lett. 2009, 9, 666-671