Ampicillin alone and in combination with riboflavin modulates Staphylococcus aureus infection induced septic arthritis in mice

Indian Journal of Experimental Biology

Volumn 50, Issue 10, 2012, Pages 677-689

  Mal, Pinky ^a   Ghosh, Deboshree ^a   Bandyopadhyay, Debasish ^a   Dutta, Kallol ^a,b   Bishayi, Biswadev ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b NATIONAL BRAIN RESEARCH CENTRE   (India)

Author keywords

Ampicillin; Antioxidant enzymes; Cytokines; Inflammation; Reactive oxygen species; Riboflavin; S. aureus; Septic arthritis; Synovial inflammation; Toxic shock syndrome toxin

Indexed keywords

AMPICILLIN; ANTIINFECTIVE AGENT; ANTIOXIDANT; BACTERIAL DNA; CATALASE; CYTOKINE; GLUTATHIONE; PHOTOSENSITIZING AGENT; RIBOFLAVIN; SUPEROXIDE DISMUTASE;

ANIMAL; ARTICLE; DRUG COMBINATION; DRUG EFFECT; GENETICS; INFECTIOUS ARTHRITIS; MALE; METABOLISM; MICROBIOLOGY; MOUSE; NEUTROPHIL; OXIDATIVE STRESS; PATHOGENICITY; SPLEEN; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SYNOVIAL FLUID; WESTERN BLOTTING;

AMPICILLIN; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIOXIDANTS; ARTHRITIS, INFECTIOUS; BLOTTING, WESTERN; CATALASE; CYTOKINES; DNA, BACTERIAL; DRUG THERAPY, COMBINATION; GLUTATHIONE; MALE; MICE; NEUTROPHILS; OXIDATIVE STRESS; PHOTOSENSITIZING AGENTS; RIBOFLAVIN; SPLEEN; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SUPEROXIDE DISMUTASE; SYNOVIAL FLUID;

EID: 84867786936     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Goldenberg D L, A recent review of nongonococcal and gonococcal arthritis, Lancet, 351 (1998) 197.
2. Esterhai J L Jr & Gelb I, Adult septic arthritis, Orthop Clin North Am, 22 (1991) 503.
3. Bremell T, Abdelnour A & Tarkowski A, Histopathological and serological progression of experimental Staphylococcus aureus arthritis, Infect Immun, 60 (1992) 2976.
4. Abdelnour A, Bremell T, Holmdahl R & Tarkowski A, Role of T lymphocytes in experimental Staphylococcus aureus arthritis, Scand J Immunol. 39 (1994) 403.
5. Kelley W N, Harris E D, Ruddy S & Sledge C B, Bacterial arthritis, in Text Book of Rheumatology(W. B. Saunders Co., Philadelphia) 1997, 1435.
6. Abbas M & Monireh M, The role of reactive oxygen species in immunopathogenesis of rheumatoid arthritis, Iran J Allergy Asthma Immunol, 7 (2008) 195.
7. Warner A, Bencosme A, Healy D & Verme C, Prognostic role of antioxidant enzymes in sepsis: preliminary assessment, Clin Chem, 41 (1995) S.867.
8. Greenwald R A, Oxygen radicals, inflammation, and arthritis: pathophysiological considerations and implications for treatment, Semin Arthritis Rheum, 20 (1991) 219.
9. Guzik T J, Korbut R & Guzik T A. Nitric oxide andsuperoxide in inflammation and immune regulation, J Physio Pharmacol, 54 (2003) 469.
10. Shull S, Heintz N H, Periasamy M, Manohar M, Janssen Y M, Marsh J P & Mossman B T, Differential regulation of antioxidant enzymes in response to oxidants, J Biol Chem, 266 (1991) 24398.
11. Knight J A, Review: free radicals, antioxidants, and the immune system, Ann Clin Lab Sci, 30 (2000) 45.
12. Brennan F M, Role of cytokines in experimental arthritis, Clin Exp Immunol, 97 (1994) 1.
13. Tarkowski A, Infectious arthritis, Best Pract Res Clin Rheumatol, 20 (2006) 1029.
14. Benedicte F & Dana J P, Recognition of Staphylococcus aureus by the innate immune system, Clin Microb Rev, 18 (2005) 521.
15. Sakiniene E, Bremell T & Tarkowski A, Addition of corticosteroids ameliorates the course of experimental Staphylococcus aureus arthritis, Arthritis Rheum, 39 (1996) 1596.
16. Tarkowski A & Wagner H, Arthritis and sepsis caused by Staphylococcus aureus: can the tissue injury be reduced by modulating the host's immune system. Mol Med Today, 4 (1998) 15.
17. Nizet V, Understanding how leading bacterial pathogens subvert innate immunity to reveal novel therapeutic targets, Molecular mechanisms in allergy and clinical immunology, J Allergy Clin Immunol, 120 (2007) 13.
18. Cheng C H, Chang S L, Lee B J, Lin K L & Huang Y C, Vitamin B6 supplementation increases immune responses in critically ill Patients, Eur J Clin Nutr, 60 (2006) 1207.
19. Seekamp A, Hultquist D E & Till G O. Protection by vitamin B2 against oxidant-mediated acute lung injury, Inflammation, 23 (1999) 449.
20. Verdrengh M & Tarkowski A, Riboflavin in innate and acquired immune responses, Inflamm Res, 4 (2005) 390.
21. Sakiniene E & Collins L V, Combined antibiotic and free radical trap treatment is effective at combating Staphylococcus aureus induced septic arthritis, Arthritis Res, 4 (2002) 196-200.
22. Snyder J R, Pascoe J R & Hirsh D C. Antimicrobial susceptibility of microorganisms isolated from equine orthopedic patients, Vet Surg, 16 (1987) 197.
23. Sen R, Das D & Bishayi B. Staphylococcal catalase regulates its virulence and induces arthritis in catalase deficient mice, Indian J Physiol Pharmacol, 53 (2009) 307.
24. Majumdar S, Dutta K, Manna S K, Basu A & Bishayi B, Possible protective role of chloramphenicol in TSST-1 and coagulase-positive Staphylococcus aureus-induced septic arthritis with altered levels of inflammatory mediators, Inflammation, 34 (2011) 269.
25. Grunberg E R, Cleeland G, Beskid G, & DeLorenzo W, In vivo activity of amoxicillin and ampicillin against Grampositive bacteria: results of prophylactic studies, J Infect Dis, 138 (1978) 872.
26. Hultgren O, Eugster H P, Sedgwick J D, Korner H & Tarkowski A, TNF/lymphotoxin-alpha double-mutant mice resist septic arthritis but display increased mortality in response to Staphylococcus aureus, J Immunol, 161 (1998) 5937.
27. Burchill M A, Nardelli D T, England D M, DeCoster D J, Christopherson J A, Callister S M & Schell R F, Inhibition of Interleukin-17 Prevents the Development of Arthritis in Vaccinated Mice Challenged with Borrelia burgdorferi, Infect Immun, 71(2003) 3437.
28. Reitman S & Frankel A, Colorimetric method for the determination of serum glutamic oxalo acetic acid and glutamic pyruvic transaminases, Am J Clin Pathol, 28 (1957) 56.
29. Chattopadhyay A, Biswas S, Bandyopadhyay D, Sarkar C & Datta A G, Effect of isoproterenol on lipid peroxidation and antioxidant enzymes of myocardial tissue of mice and protection by quinidine, Mol Cell Biochem, 245 (2003) 43.
30. Sedlak J & Lindsay R H, Estimation of total protein bound and non-protein sulfhydryl groups in tissue with Ellman's Reagent, Anal Biochem, 25 (1968) 192.
31. Martin J P, Dailey Jr M M & Sugarman E, Negative and positive assays of superoxide dismutase based on hematoxylin autooxidation, Arch Biochem Biophys, 255 (1987) 3329.
32. Beers R F & Sizer I W, A spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase, J Biol Chem, 195 (1952) 133.
33. Johnson W M, Tyler S D, Ewan E P, Ashton F E, Pollard D R & Rozee K R, Detection of genes for enterotoxins, exfoliative toxins, and toxic shock syndrome toxin 1 in Staphylococcus aureus by the polymerase chain reaction, J Clin Microbiol, 29 (1991) 426.
34. Becker K, Rotn R & Peters G, Rapid and specific detection of toxicogenic S. aureus. Use of two multiplex PCR enzyme immunoassay for amplification and hybridization of staphylococcal enterotoxin gene, exfoliative toxin gene, and toxic shock syndrome toxin 1 gene, J Clin Microbiol, 36 (1998) 2548.
35. Das D & Das A, Analysis of variance, in Statistics in Biology and Psychology (Academic Publisher, Calcutta) 2005, 280.
36. Weston V C, Jones A C, Bradbury N, Fawthrop F & Doherty M, Clinical features and outcome of septic arthritis in a single UK health district 1982-1991, Ann Rheum Dis, 58 (1999) 214.
37. Gjertsson I, Hultgren O H & Tarkowski A, Interleukin-10 ameliorates the outcome of Staphylococcus aureus arthritis by promoting bacterial clearance, Clin Exp Immunol, 130 (2002) 409.
38. Sasaki S, Nishikawa S, Miura T, Mizuki M, Yamada K, Madarame H, Tagawa Y I, Iwakura Y & Nakane A, Interleukin-4 and Interleukin-10 are involved in host resistance to Staphylococcus aureus infection through regulation of gamma interferon, Infect Immun, 68 (2000) 2424.
39. Iwanaga K, Hasegawa T, Hultquist D E, Harada H, Yoshikawa Y, Yanamadala S, Liao H, Visovatti SH & Pinsky DJ, Riboflavin-mediated reduction of oxidant injury, rejection, and vasculopathy after cardiac allotransplantation, Transplantation, 83 (2007) 747.
40. Bonomi H R, Marchesini M I, Klinke S, Ugalde J E, Zylberman V, Ugalde R A, Comerci D J & Goldbaum F A, An atypical riboflavin pathway is essential for Brucella abortus virulence, PLoS One, 5 (2010) 1.