Arrhythmogenic right ventricular cardiomyopathy 2012: Diagnostic challenges and treatment

Journal of Cardiovascular Electrophysiology

Volumn 23, Issue 10, 2012, Pages 1149-1153

  Marcus, Frank I ^a   Abidov, Aiden ^a  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

arrhythmogenic right ventricular cardiomyopathy; implantable cardioverter defibrillator; RV dysplasia; sudden death; ventricular tachycardia

Indexed keywords

AMIODARONE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; FLECAINIDE; SOTALOL;

AGE; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CARDIOVASCULAR RISK; CATHETER ABLATION; COMPUTER ASSISTED TOMOGRAPHY; ELECTROCARDIOGRAM; FAINTNESS; HEART LEFT VENTRICLE FAILURE; HEART PALPITATION; HEART RIGHT VENTRICLE DYSPLASIA; HEART RIGHT VENTRICLE FUNCTION; HEART RIGHT VENTRICLE HYPERTROPHY; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HEART VENTRICLE WALL MOTION; HUMAN; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; MEDICAL HISTORY; NONHUMAN; PRIORITY JOURNAL; RISK MANAGEMENT; T WAVE INVERSION; TWO DIMENSIONAL ECHOCARDIOGRAPHY;

ADULT; AGE FACTORS; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; BIOPSY; CATHETER ABLATION; DEATH, SUDDEN, CARDIAC; DEFIBRILLATORS, IMPLANTABLE; DIAGNOSTIC IMAGING; ELECTRIC COUNTERSHOCK; ELECTROCARDIOGRAPHY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; PHENOTYPE; PREDICTIVE VALUE OF TESTS; RISK FACTORS; TACHYCARDIA, VENTRICULAR; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT; VENTRICULAR FUNCTION, RIGHT;

EID: 84867742914     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2012.02412.x     Document Type: Article

References (35)

1. Hauer RNW, Marcus FI, Cox MGJP,: Arrhythmogenic right ventricular dysplasia/cadiomyopathy. In:, Chatterjee K, Abboud F, Anderson M, Heistad D, Kerber R, eds. Cardiology-An Illustrated Text book. London: JP Medical LTD; pp. 705-716.
2. Marcus FI, Zareba W,: The electrocardiogram in right ventricular cardiomyopathy/dysplasia. How can the electrocardiogram assist in understanding the pathologic and functional changes of the heart in this disease? J Electrocardiology 2009; 42: 136.el-136.e5.
3. 1 in young normal individuals and usefulness for the diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia. Am J Cardiol 2005; 95: 1070-1071.
4. Papadakis M, Carre F, Kervio G, Rawlins J, Panoulas VF, Chandra N, Basavarajaiah S, Carby L, Fonesca T, Sharma S,: The prevalence, distribution, and clinical outcomes of electrocardiographic repolarization patterns in male athletes of African/Afro-Caribbean origin. Eur Heart J 2011; 32: 2304-2313.
5. Morin DP, Mauer AC, Gear K, Zareba W, Markowitz SM, Marcus FI, Lerman BB,: Usefulness of precordial T-wave inversion to distinguish arrhythmogenic right ventricular cardiomyopathy from idiopathic ventricular tachycardia arising from the right ventricular outflow tract. Am J Cardiol 2010; 105: 1821-1824.
6. Ainsworth CD, Skanes AC, Klein GJ, Gula LJ, Yee R, Krahn AD,: Differentiating arrhythmogenic right ventricular cardiomyopathy from right ventricular outflow tract ventricular tachycardia using multilead QRS duration and axis. Heart Rhythm 2006; 3: 416-423.
7. Hoffmayer KS, Machado ON, Marcus GM, Yang Y, Johnson CJ, Ermakov S, Vittinghoff E, Pandurangi U, Calkins H, Cannom D, Gear KC, Tichnell C, Park Y, Zareba W, Marcus FI, Scheinman MM,: Electrocardiographic comparison of ventricular arrhythmias in patients with arrhythmogenic right ventricular cardiomyopathy and right ventricular outflow tract tachycardia. J Am Coll Cardiol 2011; 58: 831-838.
8. Pezawas T, Stix G, Kastner J, Schneider B, Woltz M, Schmidinger H,: Ventricular tachycardia in arrhythmogenic right ventricular dysplasia/ cardiomyopathy: Clinical presentation, risk stratification and results of long-term follow-up. Int J Cardiol 2006; 107: 360-368.
9. Fontaine G, Fontaliran F, Hébert JL, Chemla D, Zenati O, Lecarpentier Y, Frank R,: Arrhythmogenic right ventricular dysplasia. Annu Rev Med 1999; 50: 17-35.
10. Polin GM, Haqqani H, Tzou W, Hutchinson MD, Garcia FC, Callans DJ, Zado ES, Marchlinski FE,: Endocardial unipolar voltage mapping to identify epicardial substrate in arrhythmogenic right ventricular cardiomyopathy/dysplasia. Heart Rhythm 2011; 8: 76-83.
11. Avella A, D'Amati G, Pappalardo A, Re F, Silenzi PF, Laurenzi F, De Girolamo P, Pelargonio G, Russo AD, Baratta P, Messina G, Zecchi P, Zachara E, Tondo C,: Diagnostic value of endomyocardial biopsy guided by electroanatomic voltage mapping in arrhythmogenic right ventricular cardiomyopathy/dysplasia. J Cardiovasc Electrophysiol 2008; 19: 1127-1134.
12. Corrado D, Basso C, Leoni L, Tokajuk B, Bauce B, Frigo G, Tarantini G, Napodano M, Turrini P, Ramondo A, Daliento L, Nava A, Buja G, Iliceto S, Thiene G,: Three-dimensional electroanatomic voltage mapping increases accuracy of diagnosing arrhythmogenic right ventricular cardiomyopathy/dysplasia. Circulation 2005; 111: 3042-3050.
13. Basso C, Ronco F, Marcus FI, Abudureheman A, Rizzo S, Frigo AC, Bauce B, Maddalena F, Nava A, Corrado D, Grigoletto F, Thiene G,: Quantitative assessment of endomyocardial biopsy in arrhythmogenic right ventricular cardiomyopathy/dysplasia: An in vitro validation of diagnostic criteria. Eur Heart J 2008; 29: 2760-2771.
14. Basso C, Corrado D, Marcus FI, Nava A, Thiene G,: Arrhythmogenic right ventricular cardiomyopathy. Lancet 2009; 373: 1289-1300.
15. Indik JH, Dallas WJ, Gear K, Tandri H, Bluemke DA, Moukabary T, Marcus FI,: Right ventricular volume analysis by angiography in right ventricular cardiomyopathy. Int J of Cardiovasc Imaging 2012; 28: 995-1001.
16. Asimaki A, Tandri H, Huang H, Haushka MK, Gautam S, Basso C, Thiene G, Tsatsopoulou A, Protonotarios N, McKenna WJ, Calkins H, Saffitz JE,: A new diagnostic test for arrhythmogenic right ventricular cardiomyopathy. N Engl J Med 2009; 360: 1075-1084.
17. Sen-Chowdhry S, Syrris P, Ward D, Asimaki A, Sevdalis E, McKenna WJ,: Clinical and genetic characterization of families with arrhythmogenic right ventricular dysplasia/cardiomyopathy provides novel insights into patterns of disease expression. Circulation 2007; 115: 1710-1720.
18. Marcus FI, McKenna WJ, Sherrill D, Basso C, Bauce B, Bluemke DA, Calkins H, Corrado D, Cox MGPJ, Daubert JP, Fontaine G, Gear K, Hauer R, Nava A, Picard MH, Protonotarios N, Saffitz JE, Sanborn DMY, Steinberg JS, Tandri H, Thiene G, Towbin JA, Tsatsopoulou A, Wichter T, Zareba W,: Diagnosis of arrhythmogenic right ventricular cardiomyopathy/dysplasia: Proposed modification of the Task Force Criteria. Circulation 2010; 121: 1533-1541.
19. Marcus FI, Zareba W, Calkins H, Towbin JA, Basso C, Bluemke DA, Estes M, Picard MH, Sanborn D, Thiene G, Wichter T, Cannom D, Wilber DJ, Scheinman M, Duff H, Daubert J, Talajic M, Krahn A, Sweeney M, Garan H, Sakaguchi S, Lerman BB, Kerr C, Kron J, Steinberg JS, Sherrill D, Gear K, Brown M, Severski P, Polonsky S, McNitt S,: Arrhythmogenic right ventricular cardiomyopathy/dysplasia clinical presentation and diagnostic evaluation: Results from the North American Multidisciplinary Study. Heart Rhythm 2009; 6: 984-992.
20. Cox MGPJ, van der Zwaag PA, van der Werf C, van der Smagt JJMD,;, Noorman M, Bhuiyan ZA, Wiesfeld ACP, Volders PGA, van Langen IM, Atsma DE, Dooijes D, van den Wijngaard A, Houweling AC, Jongbloed JDH, Jordaens L, Cramer MJ, Doevendans PA, de Bakker JMT, Wilde AAM, van Tintelen JP, Hauer RNW,: Arrhythmogenic right ventricular dysplasia/cardiomyopathy. Pathogenic desmosome mutations in index-patients predict outcome of family screening: Dutch arrhythmogenic right ventricular dysplasia/cardiomyopathy genotype-phenotype follow-up study. Circulation 2011; 123: 2690-2700.
21. Corrado D, Basso C, Rizzoli G, Schiavon M, Thiene G,: Does sports activity enhance the risk of sudden death in adolescents and young adults? J Am Coll Cardiol 2003; 42: 1959-1963.
22. Xu T, Yang Z, Vatta M, Rampazzo A, Beffagna G, Pillichou K, Scherer SE, Saffitz J, Kravitz J, Zareba W, Danieli GA, Lorenzon A, Nava A, Bauce B, Thiene G, Basso C, Calkins H, Gear K, Marcus FI, Towbin JA,: Compound and digenic heterozygosity contributes to arrhythmogenic right ventricular cardiomyopathy. J Am Coll Cardiol 2010; 55: 587-597.
23. Quarta G, Muir A, Pantazis A, Syrris P, Gehmlich K, Garcia-Pavia P, Ward D, Sen-Chowdhry S, Elliott PM, McKenna WJ,: Familial evaluation in arrhythmogenic right ventricular cardiomyopathy. Circulation 2011; 123: 2701-2709.
24. Bomma C, Rutberg J, Tandri H, Nasir K, Roguin A, Tichnell C, Rodriguez R, James C, Kasper E, Spevak P, Bluemke DA, Calkins H,: Misdiagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy. J Cardiovasc Electrophysiol 2004; 15: 300-306.
25. Sorrell VL, Kumar S, Kalra N,: Cardiac imaging in right ventricular cardiomyopathy/dysplasia-How does cardiac imaging assist in understanding the morphologic, functional, and electrical changes of the heart in this disease? J Electrocardiol 2009; 42: 137.e1-137.e10.
26. Buechel ERV, Mertens LL,: Imaging the right heart: The use of integrated multimodality imaging. Eur Heart J 2012; 33: 949-960.
27. Yoerger DM, Marcus FI, Sherrill D, Calkins H, Towbin JA, Zareba W, Picard MH,: Echocardiographic findings in patients meeting Task Force Criteria for arrhythmogenic right ventricular dysplasia: New insights from the multidisciplinary study of right ventricular dysplasia. J Am Coll Cardiol 2005; 45: 860-865.
28. Rudski LG, Lai WW, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K, Solomon SD, Louie EK, Schiller NB,: Guidelines for the echocardiographic assessment of the right heart in adults: A report from the American Society of Echocardiography. J Am Soc Echocardiogr 2010; 23: 685-713.
29. Tandri H, Bomma C, Calkins H, Bluemke DA,: Magnetic resonance and computed tomography imaging of arrhythmogenic right ventricular dysplasia. J Magn Reson Imaging 2004; 19: 848-858.
30. Corrado D, Silvano M, Migliore F, Marinelli A, Leoni L, Thiene G, Iliceto S, Buja G,: Implantable cardioverter defibrillator in arrhythmogenic cardiomyopathy. Cardiac Electrophysiology Clinics 2011; 3: 311-321.
31. Bai R, Di Biase L, Shivkumar K, Mohanty P, Tung R, Santangeli P, Saenz LC, Vacca M, Verma A, Khaykin Y, Mohanty S, Burkhardt JD, Hongo R, Beheiry S, Dello Russo A, Casella M, Pelargonio G, Santarelli P, Sanchez J, Tondo C, Natale A,: Ablation of ventricular arrhythmias in arrhythmogenic right ventricular dysplasia/cardiomyopathy: Arrhythmia-free survival after endo-epicardial substrate based mapping ablation. Circulation 2011; 4: 478-485.
32. Sacher F, Roberts-Thomson K, Maury P, Tedrow U, Nault I, Steven D, Hocini M, Koplan B, Leroux L, Derval N, Seiler J, Wright MJ, Epstein L, Haissaguerre M, Jais P, Stevenson WG,: Epicardial ventricular tachycardia ablation: A multicenter safety study. J Am Coll Cardiol 2010; 55: 2366-2372.
33. Wichter T, Borggrefe M, Haverkamp W, Chen X, Breithardt G,: Efficacy of antiarrhythmic drugs in patients with arrhythmogenic right ventricular disease. Results in patients with inducible and noninducible ventricular tachycardia. Circulation 1992; 86: 29-37.
34. Marcus GM, Glidden DV, Polonsky B, Zareba W, Smith LM, Cannom DS, Estes M III, Marcus FI, Scheinman MM,: Efficacy of antiarrhythmic drugs in arrhythmogenic right ventricular cardiomyopathy. J Am Coll Cardiol 2009; 54: 609-617.
35. Fabritz L, Hoogendijk MG, Scicluna BP, van Amersfoorth SCM, Fortmueller L, Wolf S, Laakmann S, Kreienkamp N, Piccini I, Breithardt G, Noppinger PR, Witt H, Ebnet K, Wichter T, Levkau B, Franke WW, Pieperhoff S,: Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice. J Am Coll Cardiol 2011; 57: 740-750.