Load-reducing therapy prevents development of arrhythmogenic right ventricular cardiomyopathy in plakoglobin-deficient mice

Journal of the American College of Cardiology

Volumn 57, Issue 6, 2011, Pages 740-750

  Fabritz, Larissa ^a   Hoogendijk, Mark G ^b   Scicluna, Brendon P ^b   Van Amersfoorth, Shirley C M ^b   Fortmueller, Lisa ^a   Wolf, Susanne ^a   Laakmann, Sandra ^a   Kreienkamp, Nina ^a   Piccini, Ilaria ^a   Breithardt, Gnter ^a   Ruiz Noppinger, Patricia ^c   Witt, Henning ^c   Ebnet, Klaus ^d   Wichter, Thomas ^e   Levkau, Bodo ^f   Franke, Werner W ^g   Pieperhoff, Sebastian ^g   De Bakker, Jacques M T ^b,h   Coronel, Ruben ^b   Kirchhof, Paulus ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

^c DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^d ZMBE   (Germany)

^e Klinisches Herzzentrum Osnabrck Bad Rothenfelde ^*  (Germany)

^f UNIVERSITY HOSPITAL ESSEN   (Germany)

^g GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^h ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

Author keywords

arrhythmogenic right ventricular cardiomyopathy; plakoglobin; pre load reduction; transgenic mice

Indexed keywords

BETA CATENIN; CONNEXIN 43; DRINKING WATER; FUROSEMIDE; ISOSORBIDE DINITRATE; MOLSIDOMINE; NERVE CELL ADHESION MOLECULE; NITRATE; PLACEBO; PLAKOGLOBIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DRUG TOLERABILITY; ECHOCARDIOGRAPHY; ELECTROPHYSIOLOGY; HEART RIGHT VENTRICLE DYSPLASIA; HEART VENTRICLE TACHYCARDIA; HETEROZYGOSITY; IMMUNOHISTOLOGY; ISOLATED HEART; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; CARDIAC VOLUME; CONNEXIN 43; DISEASE MODELS, ANIMAL; DIURETICS; FUROSEMIDE; GAMMA CATENIN; HYPERTROPHY, RIGHT VENTRICULAR; MICE; MYOCARDIUM; NITRATES; PHOSPHORYLATION; PHYSICAL CONDITIONING, ANIMAL; RANDOM ALLOCATION; TACHYCARDIA, VENTRICULAR; VENTRICULAR PRESSURE;

EID: 79551542005     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2010.09.046     Document Type: Article

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