Effect of chronic administration of endothelin receptor type a antagonist (BQ-610) on functional lifespan of the corpus luteum in sheep

Revista Cientifica de la Facultad de Ciencias Veterinarias de la Universidad del Zulia

Volumn 22, Issue 4, 2012, Pages 321-331

  Ganchou, Fernando Perea ^a   Mankey, Julie Elizabeth ^b   Goravanahally, Madhusudan Puttaswamy ^c   Inskeep, Emmett Keith ^b   Flores, Jorge Antonio ^c  

^a UNIVERSIDAD DE LOS ANDES   (Venezuela)

^b Forestry and Consumer Sciences   (United States)

^c WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

Endothelin receptor type A; Progesterone; Prostaglandin F 2 ; Sheep; Spontaneous luteolysis

Indexed keywords

EID: 84867728971     PISSN: 07982259     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. ACOSTA, T.J.; YOSHIZAWA, N.; OHTANI, M.; MIYAMOTO, A. Local changes in blood flow within the early and midcycle corpus luteum after prostaglandin F(2 alpha) injection in the cow. Biol. Reprod. 66:651-658. 2002.
2. BRADEN, T.D.; GAMBONI, F.; NISWENDER, G.D. Effects of prostaglandin F2 alpha-induced luteolysis on the populations of cells in the ovine corpus luteum. Biol. Reprod. 39:245-253. 1988.
3. CHAMI, M.; PRANDINI, A.; CAMPANELLA, M.; PINTON, P.; SZABADKAI, G.; REED, J.C.; RIZZUTO, R. Bcl-2 and Bax exert opposing effects on Ca2+ signaling, which do not depend on their putative pore-forming region. J. Biol. Chem. 279:54581-54589. 2004.
4. CHOUDHARY, E.; COSTINE, B,A.; WILSON, M.E.; INSKEEP, E,K.; FLORES, J.A. Prostaglandin F2 (PGF2) independent and dependent regulation of the bovine luteal endothelin system. Dom. Anim. Endocrinol. 27:63-79. 2004.
5. 2α-stimulated increases in intracellular calcium concentrations in small and large ovine luteal cells. Biol. Reprod. 82:282-288. 2010.
6. DOERR, M.D.; GORAVANAHALLY, M.P.; RHINEHART, J.D.; INSKEEP, E.K.; FLORES, J.A. Effects of endothelin receptor type-A and type-B antagonists on prostaglandin F2alpha-induced luteolysis of the sheep corpus luteum. Biol. Reprod. 78:688-696. 2008.
7. GIRSH, E.; MILVAE, R.A.; WANG, W.; MEIDAN, R. Effect of endothelin-1 on bovine luteal cell function: role in prostaglandin PGF2-induced antisteroidogenic action. Endocrinol. 137:1306-1312. 1996.
8. GIRSH, E.; WANG, W.; MAMLUK, R.; ARDITI, F.; FRIEDMAN, A.; MILVAE, R.A.; MEIDAN, R. Regulation of endothelin-1 expression in the bovine corpus luteum: elevation by prostaglandin PGF2α. Endocrinol. 137:5191-5196. 1996.
9. GORAVANAHALLY, M.P.; SALEM, M.; YAO, J.; INSKEEP, E.K.; FLORES J.A. Differential gene expression in the bovine corpus luteum during transition from early to mid-phase and its potential role in acquisition of luteolytic sensitivity to prostaglandin F2α. Biol. Reprod. 80:980-988. 2009.
10. HARMS, P.G.; MALVEN, P.V.; NISWENDER, G. Progesterone and luteinizing hormone secretion during luteal inhibition by exogenous oxytocin Biol. Reprod. 3:228-233. 1969.
11. HINCKLEY, S.T.; MILVAE, R.A. Endothelin-1 mediates prostaglandin F2α-induced luteal regression in the ewe. Biol. Reprod. 64:1619-1623. 2001.
12. JAROSZEWSKI, J.J.; SKARZYNSKI, D.J.; HANSEL, W. Nitric oxide as a local mediator of prostaglandin F2α-induced regression in bovine corpus luteum: an in vivo study. Exp. Biol. Med. 228:1057-1062. 2003.
13. JUENGEL, J.L.; HAWORTH, J.D.; ROLLYSON, M.K.; SILVA, P,J.; SAWYER, H.R.; NISWENDER, G.D. Effect of dose of prostaglandin F(2alpha) on steroidogenic components and oligonucleosomes in ovine luteal tissue. Biol. Reprod. 62:1047-1051. 2000.
14. KANE, D.J.; SARAFIAN, T.A.; ANTON, R.; HAHN, H.; GRALLA, E.B.; VALENTINE, J.S.; ORD, T.; BREDESEN, D.E. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Sci. 262:1274-1277. 1993.
15. KEATOR, C.S.; SCHREIBER, D.T.; HOAGLAND, T.A.; MCCRACKEN, J.A.; MILVAE, R.A. Intrauterine infusion of BQ-610, an endothelin type A receptor antagonist, delays luteolysis in dairy heifers. Dom. Anim. Endocrinol. 34:411-418. 2008.
16. KEDZIERSKI, R.M.; YANAGISAWA, M. Endothelin system: the double-edged sword in health and disease. Annu. Rev. Pharmacol. Toxicol. 41:851-876. 2001.
17. LEWIS, G.S.; WILSON, L. JR.; WILKS, J.W.; PEXTON, J.E.; FOGWELL, R.L.; FORD, S.P.; BUTCHER, R.L.; THAYNE, W.V.; INSKEEP, E.K. PGF2 alpha and its metabolites in uterine and jugular venous plasma and endometrium of ewes during early pregnancy. J. Anim. Sci. 45:320-327. 1977.
18. MAMLUK, R.; LEVY, N.; RUEDA, B.; DAVIS, J.S.; MEIDAN, R. Characterization and regulation of type A endothelin receptor gene expression in bovine luteal cell type. Endocrinol. 140:2110-2116. 1999.
19. McCRACKEN, J.A.; GLEW, M.E.; SCARAMUZZI, R. Corpus luteum regression induced by prostaglandin F2. J. Clin. Endocrinol. Metab. 30:544-546. 1970.
20. MIYAMOTO, A.; KOBAYASHI, S.; ARATA, S.; OHTANI, M.; FUKUI, Y.; SCHAMS, D. Prostaglandin F2α promotes the inhibititory action of endothelin-1 on the bovine luteal function in vitro. J. Endocrinol. 152:R7-R11. 1997.
21. MURDOCH, W.J. Microtubular dynamics in granulosa cells of periovulatory follicles and granulosa-derived (large) lutein cells of sheep: relationships to the steroidogenic folliculo-luteal shift and functional luteolysis. Biol. Reprod. 54:1135-1140. 1996.
22. NETT, T.M.; McCLELLAN, M.C.; NISWENDER, G.D. Effects of prostaglandins on the ovine corpus luteum: bloodflow, secretion of progesterone and morphology. Biol. Reprod. 15:66-78. 1976.
23. NETT, T.M.; STAIGMILLER, R.B.; AKBAR, A.M.; DIEKMAN, M.A.; ELLINWOOD, W.E.; NISWENDER, G.D. Secretion of prostaglandin F2alpha in cycling and pregnant ewes. J. Anim. Sci. 42:876-880. 1976.
24. NEUVIANS, T.P.; SCHAMS, D.; BERISHA, B.; PFAFFL, M.W. Involvement of pro-inflammatory cytokines, mediators of inflammation, and basic fibroblast growth factor in prostaglandin F2alpha-induced luteolysis in bovine corpus luteum. Biol. Reprod. 70:473-480. 2004.
25. NISHIMURA, R.; KOMIYAMA, J.; TASAKI, Y.; ACOSTA, T.J.; OKUDA, K. Hypoxia promotes luteal cell death in bovine corpus luteum. Biol. Reprod. 78:529-536. 2007.
26. NISWENDER, G.D.; MOORE, R.T.; AKBAR, A.M.; NETT, T.M.; DIEKMAN, M.A. Flow of blood to the ovaries of ewes throughout the estrous cycle. Biol Reprod. 13:381-388. 1975.
27. NISWENDER, G.; JUENGEL, J.L.; SILVA, P.J.; ROLLYSON, M.K.; MCINTUSH, E.W. Mechanism controlling the function and life span of the corpus luteum. Physiol. Rev. 80:1-29. 2000.
28. NUSSDORFER, G.G.; ROSSI, G.P.; MALENDOWICZ, L.K.; MAZZOCCHI, G. Autocrine-paracrine endothelin system in physiology and pathology of steroid-secreting tissues. Pharmacol. Rev. 51:403-437. 1999.
29. NUTT, L.K.; PATAER, A.; PAHLER, J.; FANG, B.; ROTH, J.; MCCONKEY, D.J.; SWISHER, S.G. Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores. J. Biol. Chem. 277:9219-9225. 2002.
30. OKUDA, K.; KORZEKWA, A.; SHIBA,Y.AM.; MURAKAMI, S.; NISHIMURA, R.; TSUBOUCHI, M.; WOCLAWEK-POTOCKA, I.; SKARZYNSKI, D.J. Progesterone is a suppressor of apoptosis in bovine luteal cells. Biol. Reprod. 71:2065-2071. 2004.
31. PATE, J.L.; LANDIS K., P. Immune cells in the corpus luteum: friends or foes? Reprod. 122:665-676. 2001.
32. PFAFFL. M. W. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic. Acids. Res. 29:e45. 2001.
33. PINTON, P.; FERRARI, D.; MAGALHÃES, P.; SCHULZE-OSTHOFF, K.; DI VIRGILIO, F.; POZZAN, T.; RIZZUTO, R. Reduced loading of intracellular Ca(2+) stores and downregulation of capacitative Ca(2+) influx in Bcl-2-overexpressing cells. J. Cell. Biol. 148:857-862. 2000.
34. ROZEN, S.; SKALETSKY, H. Primer3 on the WWW for general users and for biologist programmers. Meth. Mol. Biol. 132:365-386. 2000.
35. RUEDA, B.R.; HENDRY, I.R.; HENDRY III, W.J.; STORMSHAK, F.; SLAYDEN, O.D.; DAVIS, J.S. Decreased progesterone levels and progesterone receptor antagonists promote apoptotic cell death in bovine luteal cells. Biol. Reprod. 62:269-276. 2000.
36. RUEDA, B.R.; TILLY, K.I.; BOTROS, I.W.; JOLLY, P.D.; HANSEN, T.R.; HOYER, P.B.; TILLY, J.L. Increased bax and interleukin-1beta-converting enzyme messenger ribonucleic acid levels coincide with apoptosis in the bovine corpus luteum during structural regression. Biol. Reprod. 56:186-193. 1997.
37. SAWYER, H.R.; NISWENDER., K.D.; BRADEN, T.D.; NISWENDER, G.D. Nuclear changes in ovine luteal cells in response to PGF2α. Dom. Anim. Endocrinol. 7:229-237. 1990.
38. SHEFFEL, C.E.; PRATT, B.R.; FERRELL, W.L.; INSKEEP, E.K. Induced corpora lutea in the postpartum beef cow. II. Effects of treatment with progestogen and gonadotropins. J. Anim. Sci. 54:830-836. 1982.
39. SHIRASUNA, K.; ASAOKA, H.; ACOSTA, T.J.; WIJAYAGUNAWARDANE, M.P.; OHTANI, M.; HAYASHI, M.; MATSUI, M.; MIYAMOTO, A. Real-time relationships in intraluteal release among prostaglandin F2α, endothelin-1, and angiotensin II during spontaneous luteolysis in the cow. Biol. Reprod. 71:1706-1711. 2004.
40. 2 in heifers. Reprod. 139:673-683. 2010.
41. SILVIA, W.J.; OTTOBRE, J.S.; INSKEEP, E.K. Concentrations of prostaglandins E2, F2 and 6-ketoprostaglandin F1 in the utero-ovarian venous plasma of nonpregnant and early pregnant ewe. Biol. Reprod. 30:936-944. 1984.
42. SMITH, M.F.; RICKE, W.A.; BAKKE, L.J.; DOW, M.P.; SMITH, G.W. Ovarian tissue remodeling: role of matrix metalloproteinases and their inhibitors. Mol. Cell. Endocrinol. 191:45-56. 2002.
43. STATISTICAL ANALYSIS SYSTEMS INSTITUTE (SAS). User's Guide. University North of Caroline, USA. Version 9. 2002.
44. STOCCO, C.; TELLERIA, C.; GIBORI, G. The molecular control of corpus luteum formation, function, and regression. Endocrinol. Rev. 28:117-149. 2007.
45. TILLY, J.L. Apoptosis and ovarian function. Rev. Reprod. 1:162-172. 1996.
46. TSAI, S.J.; ANDERSON, L.E.; JUENGEL, J.; NISWENDER, G.D.; WILTBANK, M.C. Regulation of prostaglandin F2 alpha and E receptor mRNA by prostaglandin F2 alpha in ovine corpora lutea. J. Reprod. Fert. 114:69-75. 1998.
47. TSAI, S.J.; KOT, K.; GINTHER, O.J.; WILTBANK, M.C. Temporal gene expression in bovine corpora lutea after treatment with PGF2alpha based on serial biopsies in vivo. Reprod. 121:905-913. 2001.
48. VINCENT, D.L.; INSKEEP, E.K. Role of progesterone in regulating uteroovarian venous concentrations of PGF2 alpha and PGE2 during the estrous cycle and early pregnancy in ewes. Prostagl. 31:715-733. 1986.
49. WATANABE, S.; SHIRASUNA, K.; MATSUI, M.; YAMAMOTO, D.; BERISHA, B.; SCHAMS, D.; MIYAMOTO, A. Effect of intraluteal injection of endothelin type A receptor antagonist on PGF2alpha-induced luteolysis in the cow. J. Reprod. Dev. 52:551-559. 2006.
50. WEEMS, Y.S.; JOHNSON, D.; UCHIMA, T.; RANEY, A.; LENNON, E.; GOTO, K.; BOWERS, G.; SALDAN, J.; PANG, J.; RANDEL, R.D.; WEEMS, C.W. Is endothelin-1 luteolytic or antiluteolytic in ewes? Prostagl. and Other Lipid Med. 90:63-68. 2009.
51. YADAV, V.K.; LAKSHMI, G.; MEDHAMURTHY, R. Prostaglandin F2alpha-mediated activation of apoptotic signaling cascades in the corpus luteum during apoptosis: involvement of caspase-activated DNase. J. Biol. Chem. 280:10357-10367. 2005.
52. YANAGISAWA, M.; KURIHARA, H.; KIMURA, S.; TOMOBE, Y.; KOBAYASHI, M.; MITSUI, Y.; YAZAKI, Y.; GOTO, K.; MASAKI, T. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature. 332:411-415. 1988.
53. ZARCO, L.; STABENFELDT, G.H.; BASU, S.; BRADFORD, G.E.; KINDAHL, H. Modification of prostaglandin F-2 alpha synthesis and release in the ewe during the initial establishment of pregnancy. J. Reprod. Fert. 83:527-536. 1988.
54. ZARCO, L.; STABENFELDT, G.H.; QUIRKE, J.F.; KINDAHL, H.; BRADFORD, G.E. Release of prostaglandin F-2 alpha and the timing of events associated with luteolysis in ewes with oestrous cycles of different lengths. J. Reprod. Fert. 83:517-526. 1988.