Antidiabetic ellagitannins from pomegranate flowers: Inhibition of α-glucosidase and lipogenic gene expression

Organic Letters

Volumn 14, Issue 20, 2012, Pages 5358-5361

  Yuan, Tao ^a   Ding, Yuanqing ^b   Wan, Chunpeng ^a   Li, Liya ^a   Xu, Jialin ^a   Liu, Ke ^c   Slitt, Angela ^a   Ferreira, Daneel ^b   Khan, Ikhlas A ^b   Seeram, Navindra P ^a  

^a UNIVERSITY OF RHODE ISLAND   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c UNIVERSITY OF KANSAS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GLUCOSIDASE; ANTIDIABETIC AGENT; ENZYME INHIBITOR; TANNIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; FLOWER; GENE EXPRESSION; ISOLATION AND PURIFICATION; LIPOGENESIS; LYTHRACEAE;

ALPHA-GLUCOSIDASES; ENZYME INHIBITORS; FLOWERS; GENE EXPRESSION; HYDROLYZABLE TANNINS; HYPOGLYCEMIC AGENTS; LIPOGENESIS; MOLECULAR STRUCTURE; PUNICACEAE;

EID: 84867700323     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol302548c     Document Type: Article

References (18)

1. Zimmet, P.; Alberti, K. G.; Shaw, J. Nature 2001, 414, 782-787
2. Huang, T. H. W.; Peng, G.; Kota, B. P.; Li, G. Q.; Yamahara, J.; Roufogalis, B. D.; Li, Y. Toxicol. Appl. Pharmacol. 2005, 207, 160-169
3. Li, Y.; Wen, S.; Kota, B. P.; Peng, G.; Li, G. Q.; Yamahara, J.; Roufogalis, B. D. J. Ethnopharmacol. 2005, 99, 239-244
4. Xie, Y.; Morikawa, T.; Ninomiya, K.; Imura, K.; Muraoka, O.; Yuan, D.; Yoshikawa, M. Chem. Pharm. Bull. 2008, 56, 1628-1631
5. Wang, R.; Wang, W.; Wang, L.; Liu, R.; Ding, Y.; Du, L. Fitoterapia 2006, 77, 534-537
6. Yuan, T.; Wan, C.; Liu, K.; Seeram, N. P. Tetrahedron 2012, 68, 959-964
7. Wan, C.; Yuan, T.; Li, L.; Kandhi, V.; Cech, N. B.; Xie, M.; Seeram, N. P. Bioorg. Med. Chem. Lett. 2012, 22, 597-600
8. Liu, X.; Cui, C.; Zhao, M.; Wang, J.; Luo, W.; Yang, B.; Jiang, Y. Food Chem. 2008, 109, 909-915
9. Immel, S.; Khanbabaee, K. Tetrahedron: Asymmetry 2000, 11, 2495-2507
10. Jiang, Z. H.; Wen, X. Y.; Tanaka, T.; Wu, S. Y.; Liu, Z.; Iwata, H.; Hirose, Y.; Wu, S.; Kouno, I. J. Nat. Prod. 2008, 71, 719-723
11. Farina, F.; Maestro, M. C.; Mattín, M. V.; Soria, M. L. Tetrahedron 1987, 43, 4007-4014
12. Okuda, T.; Yoshida, T.; Hatano, T.; Ito, H. In Chemistry and Biology of Ellagitannins, An Underestimated Class of Bioactive Plant Polyphenols; Quideau, S., Ed.; World Scientific Publishing: Singapore, 2009; Vol. 1, pp 1-54.
13. Ding, Y.; Li, X. C.; Ferreira, D. J. Nat. Prod. 2009, 72, 327-335
14. Diedrich, C.; Grimme, S. J. Phys. Chem. A 2003, 107, 2524-2539
15. Mayer, W.; Hoffmann, E. H.; Lösch, N.; Wolf, H.; Wolter, B.; Schilling, G. Liebigs Ann. Chem. 1984, 5, 929-938
16. Zang, M.; Zuccollo, A.; Hou, X.; Nagata, D.; Walsh, K.; Herscovitz, H.; Brecher, P.; Ruderman, N. B.; Cohen, R. A. J. Biol. Chem. 2004, 279, 47898-47905
17. Miyazaki, M.; Kim, Y. C.; Ntambi, J. M. J. Lipid Res. 2001, 42, 1018-1024
18. Krammer, J.; Digel, M.; Ehehalt, F.; Stremmel, W.; Fullekrug, J.; Ehehalt, R. Int. J. Med. Sci. 2011, 8, 599-614