Optimal Mode of clearance in critically ill patients with Acute Kidney Injury (OMAKI) - A pilot randomized controlled trial of hemofiltration versus hemodialysis: A Canadian Critical Care Trials Group project

Critical Care

Volumn 16, Issue 5, 2012, Pages

  Wald, Ron ^a,b   Friedrich, Jan O ^a,b,c   Bagshaw, Sean M ^d   Burns, Karen E A ^a,b,c   Garg, Amit X ^e   Hladunewich, Michelle A ^f,g   House, Andrew A ^e   Lapinsky, Stephen ^c,h   Klein, David ^a,b,c,i   Pannu, Neesh I ^j   Pope, Karen ⁱ   Richardson, Robert M ^k   Thorpe, Kevin ⁱ   Adhikari, Neill K J ^c,f  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

^e LONDON HEALTH SCIENCES CENTRE   (Canada)

^f SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^g Sunnybrook Health Sciences Centre   (Canada)

^h MOUNT SINAI HOSPITAL   (Canada)

ⁱ ST MICHAEL'S HOSPITAL   (Canada)

^j UNIVERSITY OF ALBERTA HOSPITAL   (Canada)

^k UNIVERSITY HEALTH NETWORK   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; CANADA; CONTINUOUS HEMODIALYSIS; CONTINUOUS HEMOFILTRATION; CONTROLLED STUDY; CRITICAL ILLNESS; DISEASE SEVERITY; FEASIBILITY STUDY; FEMALE; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE; SOLUTE; TREATMENT OUTCOME; ACUTE KIDNEY INJURY; CLINICAL TRIAL; EPIDEMIOLOGY; HEMODIALYSIS; HEMOFILTRATION; INTENSIVE CARE UNIT; MIDDLE AGED; MORTALITY; MULTICENTER STUDY;

ACUTE KIDNEY INJURY; CANADA; CRITICAL ILLNESS; FEMALE; HEMOFILTRATION; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; PILOT PROJECTS; RENAL DIALYSIS;

EID: 84867664976     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc11835     Document Type: Article

References (25)

1. Hoste EA, Schurgers M. Epidemiology of acute kidney injury: how big is the problem?. Crit Care Med 2008, 36:S146-151. 10.1097/CCM.0b013e318168c590, 18382186.
2. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C. Acute renal failure in critically ill patients: a multinational, multicenter study. Jama 2005, 294:813-818. 10.1001/jama.294.7.813, 16106006.
3. Vinsonneau C, Camus C, Combes A, Costa de Beauregard MA, Klouche K, Boulain T, Pallot JL, Chiche JD, Taupin P, Landais P, Dhainaut JF. Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial. Lancet 2006, 368:379-385. 10.1016/S0140-6736(06)69111-3, 16876666.
4. Palevsky PM, Zhang JH, O'Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RM, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P. Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 2008, 359:7-20. 2574780, 18492867.
5. Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lo S, McArthur C, McGuinness S, Myburgh J, Norton R, Scheinkestel C, Su S. Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med 2009, 361:1627-1638.
6. Ricci Z, Ronco C, D'Amico G, De Felice R, Rossi S, Bolgan I, Bonello M, Zamperetti N, Petras D, Salvatori G, Dan M, Piccinni P. Practice patterns in the management of acute renal failure in the critically ill patient: an international survey. Nephrol Dial Transplant 2006, 21:690-696. 10.1093/ndt/gfi296, 16326743.
7. Depner TA. "Artificial" hemodialysis versus "natural" hemofiltration. Am J Kidney Dis 2008, 52:403-406. 10.1053/j.ajkd.2008.07.007, 18725013.
8. Schulz KF, Altman DG, Moher D. CONSORT 2010 statement: updated guidelines for reporting parallel group randomized trials. Ann Intern Med 152:726-732.
9. Ferreira FL, Bota DP, Bross A, Melot C, Vincent JL. Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA 2001, 286:1754-1758. 10.1001/jama.286.14.1754, 11594901.
10. Doig GS, Simpson F. Randomization and allocation concealment: a practical guide for researchers. J Crit Care 2005, 20:187-191. discussion 191-183, 10.1016/j.jcrc.2005.04.005, 16139163.
11. Cappi SB, Sakr Y, Vincent JL. Daily evaluation of organ function during renal replacement therapy in intensive care unit patients with acute renal failure. J Crit Care 2006, 21:179-183. 10.1016/j.jcrc.2005.07.003, 16769463.
12. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992, 101:1644-1655. 10.1378/chest.101.6.1644, 1303622.
13. Brunet S, Leblanc M, Geadah D, Parent D, Courteau S, Cardinal J. Diffusive and convective solute clearances during continuous renal replacement therapy at various dialysate and ultrafiltration flow rates. Am J Kidney Dis 1999, 34:486-492. 10.1016/S0272-6386(99)70076-4, 10469859.
14. De Vriese AS, Colardyn FA, Philippe JJ, Vanholder RC, De Sutter JH, Lameire NH. Cytokine removal during continuous hemofiltration in septic patients. J Am Soc Nephrol 1999, 10:846-853.
15. Kellum JA, Johnson JP, Kramer D, Palevsky P, Brady JJ, Pinsky MR. Diffusive vs. convective therapy: effects on mediators of inflammation in patient with severe systemic inflammatory response syndrome. Crit Care Med 1998, 26:1995-2000. 10.1097/00003246-199812000-00027, 9875910.
16. Morgera S, Slowinski T, Melzer C, Sobottke V, Vargas-Hein O, Volk T, Zuckermann-Becker H, Wegner B, Muller JM, Baumann G, Kox WJ, Bellomo R, Neumayer HH. Renal replacement therapy with high-cutoff hemofilters: Impact of convection and diffusion on cytokine clearances and protein status. Am J Kidney Dis 2004, 43:444-453. 10.1053/j.ajkd.2003.11.006, 14981602.
17. Ricci Z, Ronco C, Bachetoni A, D'Amico G, Rossi S, Alessandri E, Rocco M, Pietropaoli P. Solute removal during continuous renal replacement therapy in critically ill patients: convection versus diffusion. Crit Care 2006, 10:R67. 10.1186/cc4903, 1550874, 16646985.
18. Daud KM, Leong G, Visvanathan R. Acute Dialytic Support for the Critically Ill: Continuous Venovenous Haemodialysis versus Continuous Venovenous Haemofiltration. International Medical Journal 2006, 13:37-42.
19. Chang JW, Lee HK, Wang WS, Kim SB, Park S-K, Lee SK, Park JS. No difference in clearance and survival between continuous hemodiltration and hemodiafiltration at the same net effluent in patients with acute renal failure. Crit Care Med 2009, 37:A473.
20. Ronco C, Bellomo R, Homel P, Brendolan A, Dan M, Piccinni P, La Greca G. Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial. Lancet 2000, 356:26-30. 10.1016/S0140-6736(00)02430-2, 10892761.
21. Saudan P, Niederberger M, De Seigneux S, Romand J, Pugin J, Perneger T, Martin PY. Adding a dialysis dose to continuous hemofiltration increases survival in patients with acute renal failure. Kidney Int 2006, 70:1312-1317. 10.1038/sj.ki.5001705, 16850022.
22. Jun M, Heerspink HJ, Ninomiya T, Gallagher M, Bellomo R, Myburgh J, Finfer S, Palevsky PM, Kellum JA, Perkovic V, Cass A. Intensities of renal replacement therapy in acute kidney injury: a systematic review and meta-analysis. Clin J Am Soc Nephrol 2010, 5:956-963. 10.2215/CJN.09111209, 2879310, 20395356.
23. Van Wert R, Friedrich JO, Scales DC, Wald R, Adhikari NK. High-dose renal replacement therapy for acute kidney injury: Systematic review and meta-analysis. Crit Care Med 2010, 38:1360-1369.
24. Claure-Del Granado R, Macedo E, Chertow GM, Soroko S, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. Effluent volume in continuous renal replacement therapy overestimates the delivered dose of dialysis. Clin J Am Soc Nephrol 2011, 6:467-475. 10.2215/CJN.02500310, 3082402, 21115626.
25. Lyndon WD, Wille KM, Tolwani AJ. Solute clearance in CRRT: prescribed dose versus actual delivered dose. Nephrol Dial Transplant 2011, 27:952-956.