Poly(propylene imine) dendrimers modified with maltose or maltotriose protect phosphorothioate oligodeoxynucleotides against nuclease activity

Biochemical and Biophysical Research Communications

Volumn 427, Issue 1, 2012, Pages 197-201

  Drzewińska, Joanna ^a   Appelhans, Dietmar ^b   Voit, Brigitte ^b   Bryszewska, Maria ^a   Klajnert, Barbara ^a  

^a UNIVERSITY OF LODZ   (Poland)

^b LEIBNIZ INSTITUTE OF POLYMER RESEARCH DRESDEN   (Germany)

Author keywords

Dendrimer; Maltotriose; Nuclease; Phosphorothioate oligonucleotides; Poly(propylene imine); PPI

Indexed keywords

DENDRIMER; MALTOSE; MALTOTRIOSE; NUCLEASE S1; OLIGONUCLEOTIDE PHOSPHOROTHIOATE; POLY(PROPYLENE IMINE); UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVITY; PH; PRIORITY JOURNAL; PROTEIN CLEAVAGE;

ANTI-HIV AGENTS; DENDRIMERS; DEOXYRIBONUCLEASES; DRUG STABILITY; HUMANS; MALTOSE; NUCLEASE PROTECTION ASSAYS; OLIGONUCLEOTIDES, ANTISENSE; PHOSPHOROTHIOATE OLIGONUCLEOTIDES; POLYPROPYLENES; TRISACCHARIDES;

EID: 84867652685     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.09.043     Document Type: Article

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