-
1
-
-
37449007904
-
The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake
-
C. Addy, H. Wright, K. Van Laere, I. Gantz, N. Erondu, and B.J. Musser The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake Cell Metab 7 2008 68 78
-
(2008)
Cell Metab
, vol.7
, pp. 68-78
-
-
Addy, C.1
Wright, H.2
Van Laere, K.3
Gantz, I.4
Erondu, N.5
Musser, B.J.6
-
3
-
-
20144364615
-
Metabotropic glutamate receptor mGlu5 is a mediator of appetite and energy balance in rats and mice
-
M.J. Bradbury, U. Campbell, D. Giracello, D. Chapman, C. King, and L. Tehrani Metabotropic glutamate receptor mGlu5 is a mediator of appetite and energy balance in rats and mice J Pharmacol Exp Ther 313 2005 395 402
-
(2005)
J Pharmacol Exp Ther
, vol.313
, pp. 395-402
-
-
Bradbury, M.J.1
Campbell, U.2
Giracello, D.3
Chapman, D.4
King, C.5
Tehrani, L.6
-
4
-
-
33746649732
-
Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation
-
C. Bucherelli, E. Baldi, C. Mariottini, M.B. Passani, and P. Blandina Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation Learn Mem 13 2006 426 430
-
(2006)
Learn Mem
, vol.13
, pp. 426-430
-
-
Bucherelli, C.1
Baldi, E.2
Mariottini, C.3
Passani, M.B.4
Blandina, P.5
-
5
-
-
3042685523
-
The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl] pyridine (MTEP) in rodent models of anxiety
-
C. Busse, J. Brodkin, D. Tattersall, J.J. Anderson, N. Warren, and L. Tehrani The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl] pyridine (MTEP) in rodent models of anxiety Neuropsychopharmacology 29 2004 1971 1979
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1971-1979
-
-
Busse, C.1
Brodkin, J.2
Tattersall, D.3
Anderson, J.J.4
Warren, N.5
Tehrani, L.6
-
6
-
-
63849228542
-
Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory
-
P. Campolongo, B. Roozendaal, V. Trezza, D. Hauer, G. Schelling, and J.L. McGaugh Endocannabinoids in the rat basolateral amygdala enhance memory consolidation and enable glucocorticoid modulation of memory Proc Natl Acad Sci U S A 106 2009 4888 4893
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4888-4893
-
-
Campolongo, P.1
Roozendaal, B.2
Trezza, V.3
Hauer, D.4
Schelling, G.5
McGaugh, J.L.6
-
8
-
-
36048995288
-
Efficacy and safety of the weight-loss drug rimonabant: A meta-analysis of randomised trials
-
[Erratum in: Lancet 2008;71:558]
-
R. Christensen, P.K. Kristensen, E.M. Bartels, H. Bliddal, and A. Astrup Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials Lancet 370 2007 1706 1713 [Erratum in: Lancet 2008;71:558]
-
(2007)
Lancet
, vol.370
, pp. 1706-1713
-
-
Christensen, R.1
Kristensen, P.K.2
Bartels, E.M.3
Bliddal, H.4
Astrup, A.5
-
9
-
-
43849090366
-
MGlu5 antagonism impairs exploration and memory of spatial and non-spatial stimuli in rats
-
G.R.J. Christoffersen, A. Simonyi, T.R. Schachtman, B. Clausen, D. Clement, and V.K. Bjerre MGlu5 antagonism impairs exploration and memory of spatial and non-spatial stimuli in rats Behav Brain Res 191 2008 235 245
-
(2008)
Behav Brain Res
, vol.191
, pp. 235-245
-
-
Christoffersen, G.R.J.1
Simonyi, A.2
Schachtman, T.R.3
Clausen, B.4
Clement, D.5
Bjerre, V.K.6
-
10
-
-
33644919174
-
1 receptor, inhibits the induction of long-term potentiation and induces retrograde amnesia in rats
-
1 receptor, inhibits the induction of long-term potentiation and induces retrograde amnesia in rats Brain Res 1075 2006 60 67
-
(2006)
Brain Res
, vol.1075
, pp. 60-67
-
-
De Oliveira, A.L.1
Pasqualini, G.B.2
Vaz, B.R.3
Pedroso, M.F.4
Costa Da Costa, J.5
Quillfeldt, J.A.6
-
11
-
-
44649153860
-
Differential role of the hippocampal endocannabinoid system in the memory consolidation and retrieval mechanisms
-
A.L. De Oliveira, B.P. Genro, F. Diehl, and J.A. Quillfeldt Differential role of the hippocampal endocannabinoid system in the memory consolidation and retrieval mechanisms Neurobiol Learn Mem 90 2008 1 9
-
(2008)
Neurobiol Learn Mem
, vol.90
, pp. 1-9
-
-
De Oliveira, A.L.1
Genro, B.P.2
Diehl, F.3
Quillfeldt, J.A.4
-
12
-
-
84868560312
-
-
Fda
-
FDA FDA briefing document, NDA 21-888, Zimulti (rimonabant) tablets, 20 mg, Sanofi Aventis Advisory Committee - June 13, 2007 http://www.fda.gov/ohrms/ dockets/AC/07/briefing/2007-4306b1-fda-backgrounder.pdf
-
FDA Briefing Document, NDA 21-888, Zimulti (Rimonabant) Tablets, 20 Mg, Sanofi Aventis Advisory Committee - June 13, 2007
-
-
-
13
-
-
16444361969
-
Effects of mGlu1 and mGlu5 receptor antagonists on negatively reinforced learning
-
A. Gravius, M. Pietraszek, D. Schafer, W.J. Schmidt, and W. Danysz Effects of mGlu1 and mGlu5 receptor antagonists on negatively reinforced learning Behav Pharmacol 16 2005 113 121
-
(2005)
Behav Pharmacol
, vol.16
, pp. 113-121
-
-
Gravius, A.1
Pietraszek, M.2
Schafer, D.3
Schmidt, W.J.4
Danysz, W.5
-
14
-
-
2942650911
-
Functional interaction between NMDA and mGlu5 receptors: Effects on working memory, instrumental learning, motor behaviors, and dopamine release
-
H. Homayoun, M.R. Stefani, B.W. Adams, G.D. Tamagan, and B. Moghaddam Functional interaction between NMDA and mGlu5 receptors: effects on working memory, instrumental learning, motor behaviors, and dopamine release Neuropsychopharmacology 29 2004 1259 1269
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1259-1269
-
-
Homayoun, H.1
Stefani, M.R.2
Adams, B.W.3
Tamagan, G.D.4
Moghaddam, B.5
-
15
-
-
4644331847
-
Cannabinoid physiology and pharmacology: 30 years of progress
-
A.C. Howlett, C.S. Breivogel, S.R. Childers, S.A. Deadwyler, R.E. Hampson, and L.J. Porrino Cannabinoid physiology and pharmacology: 30 years of progress Neuropharmacology 47 2004 345 358
-
(2004)
Neuropharmacology
, vol.47
, pp. 345-358
-
-
Howlett, A.C.1
Breivogel, C.S.2
Childers, S.R.3
Deadwyler, S.A.4
Hampson, R.E.5
Porrino, L.J.6
-
16
-
-
35548973512
-
Rapid direct excitation and long-lasting enhancement of NMDA response by group i metabotropic glutamate receptor activation of hypothalamic melanin-concentrating hormone neurons
-
H. Huang, and A.N. van den Pol Rapid direct excitation and long-lasting enhancement of NMDA response by group I metabotropic glutamate receptor activation of hypothalamic melanin-concentrating hormone neurons J Neurosci 27 2007 11560 11572
-
(2007)
J Neurosci
, vol.27
, pp. 11560-11572
-
-
Huang, H.1
Van Den Pol, A.N.2
-
17
-
-
34247895688
-
Cannabinoids excite hypothalamic melanin-concentrating hormone but inhibit hypocretin/orexin neurons: Implications for cannabinoid actions on food intake and cognitive arousal
-
H. Huang, C. Acuna-Goycolea, Y. Li, H.M. Cheng, K. Obrietan, and A.N. van den Pol Cannabinoids excite hypothalamic melanin-concentrating hormone but inhibit hypocretin/orexin neurons: implications for cannabinoid actions on food intake and cognitive arousal J Neurosci 27 2007 4870 4881
-
(2007)
J Neurosci
, vol.27
, pp. 4870-4881
-
-
Huang, H.1
Acuna-Goycolea, C.2
Li, Y.3
Cheng, H.M.4
Obrietan, K.5
Van Den Pol, A.N.6
-
18
-
-
65649122618
-
Cannabinoid receptor antagonists: Pharmacological opportunities, clinical experience, and translational prognosis
-
D.R. Janero, and A. Makriyannis Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis Expert Opin Emerg Drugs 14 2009 43 65
-
(2009)
Expert Opin Emerg Drugs
, vol.14
, pp. 43-65
-
-
Janero, D.R.1
Makriyannis, A.2
-
19
-
-
0037451844
-
22-kHz ultrasonic vocalization in rats as an index of anxiety but not fear: Behavioral and pharmacological modulation of affective state
-
P. Jelen, S. Soltysik, and J. Zagrodzka 22-kHz ultrasonic vocalization in rats as an index of anxiety but not fear: behavioral and pharmacological modulation of affective state Behav Brain Res 141 2003 63 72
-
(2003)
Behav Brain Res
, vol.141
, pp. 63-72
-
-
Jelen, P.1
Soltysik, S.2
Zagrodzka, J.3
-
20
-
-
77957679410
-
Bariatric surgery: A primer
-
S. Karmali, C.J. Stoklossa, A. Sharma, J. Stadnyk, S. Christiansen, and D. Cottreau Bariatric surgery: a primer Can Fam Physician 56 2010 873 879
-
(2010)
Can Fam Physician
, vol.56
, pp. 873-879
-
-
Karmali, S.1
Stoklossa, C.J.2
Sharma, A.3
Stadnyk, J.4
Christiansen, S.5
Cottreau, D.6
-
21
-
-
3042683441
-
Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABAA signaling
-
A. Klodzinska, E. Tatarczynska, E. Chojnacka-Wojcik, G. Nowak, N.D.P. Cosford, and A. Pilc Anxiolytic-like effects of MTEP, a potent and selective mGlu5 receptor agonist does not involve GABAA signaling Neuropharmacology 47 2004 342 350
-
(2004)
Neuropharmacology
, vol.47
, pp. 342-350
-
-
Klodzinska, A.1
Tatarczynska, E.2
Chojnacka-Wojcik, E.3
Nowak, G.4
Cosford, N.D.P.5
Pilc, A.6
-
22
-
-
33745800099
-
Cannabinoids potentiate emotional learning plasticity in neurons of the medial prefrontal cortex through basolateral amygdala inputs
-
S.R. Laviolette, and A.A. Grace Cannabinoids potentiate emotional learning plasticity in neurons of the medial prefrontal cortex through basolateral amygdala inputs J Neurosci 26 2006 6458 6468
-
(2006)
J Neurosci
, vol.26
, pp. 6458-6468
-
-
Laviolette, S.R.1
Grace, A.A.2
-
23
-
-
0036682222
-
The endogenous cannabinoid system controls extinction of aversive memories
-
G. Marsicano, C.T. Wotjak, S.C. Azad, T. Bisogno, G. Rammes, and M.G. Cascio The endogenous cannabinoid system controls extinction of aversive memories Nature 418 2002 530 534
-
(2002)
Nature
, vol.418
, pp. 530-534
-
-
Marsicano, G.1
Wotjak, C.T.2
Azad, S.C.3
Bisogno, T.4
Rammes, G.5
Cascio, M.G.6
-
25
-
-
34250855669
-
Stress-induced hyperthermia: Effects of acute and repeated dosing of MPEP
-
R.E. Nordquist, S. Durkin, G. Jaeschke, and W. Spooren Stress-induced hyperthermia: effects of acute and repeated dosing of MPEP Eur J Pharmacol 568 2007 199 202
-
(2007)
Eur J Pharmacol
, vol.568
, pp. 199-202
-
-
Nordquist, R.E.1
Durkin, S.2
Jaeschke, G.3
Spooren, W.4
-
27
-
-
33746110406
-
Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole - LH 21
-
F.J. Pavon, A. Bilbao, L. Hernández-Folgado, A. Cippitelli, N. Jagerovic, and G. Abellán Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4- dichlorophenyl)-3-hexyl-1H-1,2,4-triazole - LH 21 Neuropharmacology 51 2006 58 366
-
(2006)
Neuropharmacology
, vol.51
, pp. 58-366
-
-
Pavon, F.J.1
Bilbao, A.2
Hernández-Folgado, L.3
Cippitelli, A.4
Jagerovic, N.5
Abellán, G.6
-
28
-
-
27144537834
-
Fenobam: A clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity
-
R.H. Porter, G. Jaeschke, W. Spooren, T.M. Ballard, B. Buttelmann, and S. Kolczewski Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity J Pharmacol Exp Ther 315 2005 711 721
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 711-721
-
-
Porter, R.H.1
Jaeschke, G.2
Spooren, W.3
Ballard, T.M.4
Buttelmann, B.5
Kolczewski, S.6
-
29
-
-
50249146943
-
Endocannabinoid modulation of fear responses: Learning and state-dependent performance effects
-
C.G. Reich, M.H. Mohammadi, and B.E. Alger Endocannabinoid modulation of fear responses: learning and state-dependent performance effects J Psychopharmacol 22 2008 769 777
-
(2008)
J Psychopharmacol
, vol.22
, pp. 769-777
-
-
Reich, C.G.1
Mohammadi, M.H.2
Alger, B.E.3
-
30
-
-
35748971423
-
1 receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats
-
1 receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats Eur J Neurosci 26 2007 2643 2653
-
(2007)
Eur J Neurosci
, vol.26
, pp. 2643-2653
-
-
Roche, M.1
O'Connor, E.2
Diskin, C.3
Finn, D.P.4
-
31
-
-
0037470253
-
Stress-induced vocalisation in adult animals. A valid model of anxiety?
-
C. Sanchez Stress-induced vocalisation in adult animals. A valid model of anxiety? Eur J Pharmacol 463 2003 133 143
-
(2003)
Eur J Pharmacol
, vol.463
, pp. 133-143
-
-
Sanchez, C.1
-
32
-
-
0002897958
-
Metabotropic glutamate receptors immunocytochemical and in situ hybridization analyses
-
O.P. Ottersen, J. Storm-Mathisen, Glutamate Elsevier
-
R. Shigemoto, and N. Mizuno Metabotropic glutamate receptors immunocytochemical and in situ hybridization analyses O.P. Ottersen, J. Storm-Mathisen, Handbook of chemical neuroanatomy Glutamate vol. 18 2000 Elsevier 63 98
-
(2000)
Handbook of Chemical Neuroanatomy
, vol.18
, pp. 63-98
-
-
Shigemoto, R.1
Mizuno, N.2
-
33
-
-
77952554442
-
1 antagonist AM4113, enhances retention of contextual fear conditioning in rats
-
1 antagonist AM4113, enhances retention of contextual fear conditioning in rats Pharmacol Biochem Behav 95 2010 479 484
-
(2010)
Pharmacol Biochem Behav
, vol.95
, pp. 479-484
-
-
Sink, K.S.1
Segovia, K.N.2
Collins, L.E.3
Markus, E.J.4
Vemuri, V.K.5
Makriyannis, A.6
-
34
-
-
24344483151
-
Metabotropic glutamate receptor 1 blockade impairs acquisition and retention in a spatial water maze task
-
T. Steckler, A.F.M. Oliveira, C. Van Dyck, H. Van Craenendonck, A.M.A. Mateus, and X. Langlois Metabotropic glutamate receptor 1 blockade impairs acquisition and retention in a spatial water maze task Behav Brain Res 164 2005 52 60
-
(2005)
Behav Brain Res
, vol.164
, pp. 52-60
-
-
Steckler, T.1
Oliveira, A.F.M.2
Van Dyck, C.3
Van Craenendonck, H.4
Mateus, A.M.A.5
Langlois, X.6
-
35
-
-
77952802123
-
1 receptor transmission within the amygdala-prefrontal cortical pathway modulates neuronal plasticity and emotional memory encoding
-
1 receptor transmission within the amygdala-prefrontal cortical pathway modulates neuronal plasticity and emotional memory encoding Cereb Cortex 20 2010 1486 1496
-
(2010)
Cereb Cortex
, vol.20
, pp. 1486-1496
-
-
Tan, H.1
Lauzon, N.M.2
Bishop, S.F.3
Bechard, M.A.4
Laviolette, S.R.5
-
36
-
-
33746490030
-
1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake
-
1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake Pharmacol Biochem Behav 84 2006 353 359
-
(2006)
Pharmacol Biochem Behav
, vol.84
, pp. 353-359
-
-
Thornton-Jones, Z.D.1
Kennett, G.A.2
Benwell, K.R.3
Revell, D.F.4
Misra, A.5
Sellwood, D.M.6
-
37
-
-
58049106258
-
-
Who
-
WHO Fact sheet N°311 http://www.who.int/mediacentre/factsheets/fs311/ en/index.html 2006
-
(2006)
Fact Sheet N°311
-
-
-
38
-
-
0037177601
-
Endocannabinoid signaling in the brain
-
R.I. Wilson, and R.A. Nicoll Endocannabinoid signaling in the brain Science 296 2002 678 682
-
(2002)
Science
, vol.296
, pp. 678-682
-
-
Wilson, R.I.1
Nicoll, R.A.2
-
39
-
-
84855502083
-
Effects of endocannabinoid system modulation on cognitive and emotional behavior
-
C. Zanettini, V. Leigh, L.V. Panlilio, M. Alicki, S.R. Goldberg, and J. Haller Effects of endocannabinoid system modulation on cognitive and emotional behavior Front Behav Neurosci 5 2011 1 21
-
(2011)
Front Behav Neurosci
, vol.5
, pp. 1-21
-
-
Zanettini, C.1
Leigh, V.2
Panlilio, L.V.3
Alicki, M.4
Goldberg, S.R.5
Haller, J.6
|